Humans genome proteins expressed sequence tags. Medical search. Frequent questions

We have catalogued the protein kinase complement of the human genome (the "kinome") using public and proprietary genomic, complementary DNA, and expressed sequence tag (EST) sequences. (nordiag.com)
The genomic organization of the human genes that encode protein prenyltransferases is shown in Figure 1 . (biomedcentral.com)
The gene encoding the Ov-phy-1 open reading frame contained 11 introns, similar in structure to the gene encoding human prolyl 4-hydroxylase isoform I. Genomic Southern blot, EST and genomic PCR studies demonstrated that the O. volvulus genome contained between three and eight genes closely related to Ov-phy-1. (embl.de)
Complete genomic characterization defines human glioblastoma genes and core pathways. (nfkbcell.com)
Further studies on the involvement of 5mC in development and disease require simple methods for its analysis in genomic DNA sequences of interest. (nature.com)
However, after genome sequencing it is critical to identify and demarcate the functional elements in the genome (structural annotation) and to link these genomic elements to biological function (functional annotation). (biomedcentral.com)
Statistics for the chicken and cow genomes compared with the human, mouse and rat genomes (Table 1 ) reveal fundamental problems in genomic structural and functional annotation in livestock genomes. (biomedcentral.com)
This would result in depletion of MHC, trail receptors and IFN receptors at the host cell surface .Viral protein genome-linked: acts as a primer for viral RNA replication and rains covalently bound to viral genomic RNA. (enquirebio.com)
Genomic sequences of TEPs were retrieved after annotation of the B. glabrata genome. (ac.ir)
2009). Proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (Mus domesticus). (geneticsmr.com)
The second + or - indicates the orientation of the matching translated genomic sequence. (noncode.org)
This track may also be configured to display base labeling, a feature that allows the user to display all bases in the aligning sequence or only those that differ from the genomic sequence. (noncode.org)
Only alignments having a base identity level within 0.5% of the best and at least 96% base identity with the genomic sequence were kept. (noncode.org)
Advances in genomic sequencing technology are transforming medical discovery, enabling researchers to conduct comprehensive explorations across whole genomes for individuals and populations. (cdc.gov)

Description: Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification. (nfkbcell.com)
Description: Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification. (nfkbcell.com)
Compared to similar immune magnetic beads, our Protein A/G beads display much more antibody binding sites therefore using less magnetic beads per reaction and ultimately achiving greater cost-efficiency. (nfkbcell.com)
Monoclonal mouse Anti·His Antibodies (5xHis antibodies and 4xHis antibodies), like the RGS·His Antibody, BSA-free, Tetra·His Antibody, BSA-free and Penta·His Antibody, BSA-free are used to detect recombinant protein carrying His tags. (qiagen.com)
For the sensitivity of the three Anti·His Antibodies in detecting this panel of proteins see the figure Sensitivity of anti·His antibodies. Detection of 6xHis-tagged proteins with Anti·His Antibodies (Tetra·His Antibody in the center). A: DHFR; B: DHFR; C: thioredoxin; D: TNF-α; E: TFIIA γ ; F: chaperonin; G DNA polymerase; H: TFIIAαß; for tag location and sequences detected see table 'Proteins detected with QIA express Anti·His Antibodies'. Indicated amounts of pure 6xHis-tagged protein were applied to a nitrocellulose membrane, and detection was carried out with the Anti·His primary antibody indicated diluted 1/2000, followed by chromogenic detection with AP-conjugated rabbit anti-mouse IgG and NBT/BCIP. "> "Sensitivity of QIA express Anti·His Antibodies" ). (qiagen.com)
Anti·His Antibodies enable identification of positive expression clones by colony blotting (see figure Identification of positive expression clones by colony blotting. . "> "Identification of positive expression clones by colony blotting" ) and detection of His-tagged thioredoxin (see figure His-tagged thioredoxin detected by Penta·His Antibody in yeast cells. . "> "His-tagged thioredoxin detected by Penta·His Antibody in yeast cells" ). (qiagen.com)
No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody. (prosci-inc.com)
The Ortho HBc ELISA Test System is a qualitative enzyme-linked immunosorbent assay (ELISA) for the detection of total antibody to anti-HBc in human serum or plasma. (cdc.gov)
After washing to remove unbound material, biotin-tagged HBsAg (B-HBsAg) and rabbit anti-biotin, conjugated with horseradish peroxidase (HRPO), are incubated with the beads to form antigen-antibody-antigen "sandwich" complexes. (cdc.gov)
Qualitative determination of the human antibody directed against hepatitis C virus (anti-HCV) in human serum or plasma is measured using direct solid-phase enzyme immunoassay with the anti-HCV screening ELISA. (cdc.gov)

We report evidence from cDNA isolation and expression analysis as well as analyses of genome, expressed sequence tag (EST), cDNA and expression databases for a new gene named SPRN (shadow of prion protein). (nih.gov)
Its cDNA sequence contained an open reading frame encoding a 431-amino acid peptide that showed a significant homology with members of the P2X family. (aacrjournals.org)
The following PFDN6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). (genscript.com)
These sequences represent the protein coding region of the PFDN6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. (genscript.com)

Here, we introduce Cell Hashing, where oligo-tagged antibodies against ubiquitously expressed surface proteins uniquely label cells from distinct samples, which can be subsequently pooled. (nih.gov)
The person's immune system then recognizes the viral spike protein as foreign and produces antibodies to eliminate it. (nih.gov)
Rapid and comprehensive analysis of putative proteinous allergens ( allergenome ) by applying such a proteomic strategy … With allergenomics, we can not only detect and assign the putative allergens (proteins specifically interacting with IgE antibodies in a patient's blood) in a short time, but also analyze the quantitative and qualitative change of the antigens, depending on the surroundings and environmental conditions of an allergenic causative. (genomicglossaries.com)
For detection, QIA express mouse monoclonal antibodies are produced under conditions that guarantee the highest purity and activity. (qiagen.com)

However, systems biology from functional genomics data is hindered in agricultural species because agricultural genome sequences have relatively poor structural and functional annotation and agricultural research communities are smaller with limited funding compared to many model organism communities. (biomedcentral.com)
Proteomics is highly linked to genomics, since the blueprint for each protein is inscribed on an organism's genes. (cdc.gov)

Automatic comparisons of data from expressed sequence tags (ESTs) with genes (for example using the program Acembly, for which the results are available from the NCBI AceView server [ 2 ]) shows that all the human protein prenyltransferase genes have multiple alternative splice variants. (biomedcentral.com)
Another problem is that, compared to human and mouse, the chicken and cow have 10-fold fewer ESTs to aid in structural annotation and functional analysis. (biomedcentral.com)
It has been estimated that ~100,000 expressed sequence tags ( ESTs ) can be identified in humans. (wikidoc.org)
This track displays translated blat alignments of expressed sequence tags (ESTs) in GenBank from organisms other than human. (noncode.org)
ESTs are single-read sequences, typically about 500 bases in length, that usually represent fragments of transcribed genes. (noncode.org)
For example, to apply the filter to all ESTs expressed in a specific organ, type the name of the organ in the tissue box. (noncode.org)
To generate this track, the ESTs were aligned against the genome using blat. (noncode.org)

1999). Winter flounder expressed sequence tags: Establishment of an EST database and identification of novel fish genes. (geneticsmr.com)

The fish and mammalian sequences are also well conserved, particularly for zebrafish, to beyond the end of the hydrophobic sequence (identity 41-53%, 78 amino acids, zebrafish length). (nih.gov)
Database information indicates expression of SPRN in embryo, brain and retina of mouse and rat, hippocampus of human, and in embryo and retina of zebrafish, and we directly confirmed a strikingly specific expression of the mammalian (human, mouse, rat) transcripts in whole brain. (nih.gov)
This result together with some common structural features led to the suggestive hypothesis of a possible functional link between mammalian PrP and Sho proteins. (nih.gov)

Together, they shape a pore in the host mbrane through which viral genome is translocated to host cell cytoplasm. (enquirebio.com)
Capsid protein VP4 is released, Capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host mbrane through which the viral genome is translocated into the host cell cytoplasm. (enquirebio.com)
In turn, high levels of cyctoplasmic calcium may trigger mbrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication .Protein 2C: Induces and associates with structural rearrangents of intracellular mbranes. (enquirebio.com)

Previous data has reported similarity between human brain and testis gene expression patterns. (karger.com)
Hence, it means that human testis could also play a crucial role in human speciation if these two tissues exhibit similar gene expression patterns. (karger.com)
Determining the large scale anatomy of gene expression patterns of various human tissues could draw a more convincing conclusion, and better our understanding of the correlation/inter-correlation among different tissues. (karger.com)
Among the 17 tissues, the highest similarity in gene expression patterns was between human brain and testis, based on DDD and clustering analysis. (karger.com)
Present results provide evidence to support the proposal that human testis and brain share the highest similarity of gene expression patterns. (karger.com)
Right here we report the interim integrative evaluation of DNA copy quantity, gene expression and DNA methylation aberrations in 206 glioblastomas-the commonest kind of grownup mind cancer-and nucleotide sequence aberrations in 91 of the 206 glioblastomas. (nfkbcell.com)
This modification (methylation) is important not only in gene expression but also in ensuring that there is the right balance in the level of expression of proteins in different cells. (sciencedaily.com)
Entrez is NCBI's primary text search and retrieval system that integrates the PubMed database of biomedical literature with 38 other literature and molecular databases including DNA and protein sequence, structure, gene, genome, genetic variation and gene expression. (nih.gov)

Anticipated orthologous ORFs in the regions above were defined as BLAT (Kent 2002) or SSearch (Pearson and Lipman 1988) sequence matches. (ubc.ca)

This lack of increase contrasts with previous reports as does the mRNA length: this is 50% larger as confirmed by sequencing the 3' end. (embl.de)
When someone receives an mRNA vaccine for COVID-19, it tells the person's own cells to make the SARS-CoV-2 spike protein. (nih.gov)
Some have raised concerns on social media that mRNA vaccines might alter the DNA genome of someone being vaccinated. (nih.gov)
any "of several different forms of the same protein, arising from either single nucleotide polymorphisms, [4] differential splicing of mRNA, or post-translational modifications (e.g. sulfation, glycosylation, etc.)" [5] is called an isoform , or protein isoform . (wikidoc.org)
2003. Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. (berkeley.edu)
After mRNA processing, most transcripts are exported to the cytoplasm for translation into protein. (berkeley.edu)
Each mRNA transcript can serve as template for repeated translation into protein by ribosomes. (berkeley.edu)
The number of protein products produced by any single mRNA can vary widely. (berkeley.edu)

The genes encoding CaaX protein prenyltransferases are considerably longer than those encoding non-CaaX subunits, as a result of longer introns. (biomedcentral.com)
For example, the current Ensembl version proposes a Chiss ortholog of BLU31 (gene responsible for their characteristic blue skin), but further investigation concluded that the "gene" lacks possible introns and thus cannot produce any resemblance of a protein in wookiee. (ubc.ca)

Vaccination with these proteins resulted in an impaired establishment of adult stages and consequently a reduction in the burden of mL1 in BALB/c mice. (westminster.ac.uk)
Mice provide a suitable model for the study of human genetics because more than 95% of the genome is identical. (biomedcentral.com)
Mice are also easy to breed with a short generation time and a short life span allowing direct study of disease development and can accurately eludicidate how genetic sequences may vary in different strains and result in susceptibility to fibrotic pathologies. (biomedcentral.com)
To date, the Mouse Genome Database through The Jackson Laboratory, lists 24 QTL in mice associated with fibrosis of which all but 3 are phenotypes in the lung. (biomedcentral.com)

A collection of different allotypes or allelic protein variants, a new type of protein library. (genomicglossaries.com)
Three transcript variants encoding the same protein have been identified for this gene. (origene.com)
Each of the three variants detects a different His tag epitope. (qiagen.com)
In 2018, the Vijayanand Laboratory published a seminal Cell study that revealed the impact of genetic variants in a set of human immune cells. (ddw-online.com)
ClinVar is a public archive of submitted reports of clinically relevant human genetic variants and their relationships to phenotypes, with supporting evidence. (nih.gov)
Here, through an in-depth phylogenetic clustering analysis of upwards of 200,000 whole-genome sequences, we reveal the presence of previously unreported and hitherto unidentified mutations and recombination breakpoints in Variants of Concern (VOC) and Variants of Interest (VOI) from Brazil, India (Beta, Eta and Kappa) and the USA (Beta, Eta and Lambda). (cdc.gov)
The TAG-VE will continue to critically appraise state-of-the-art methodologies for predicting further evolution of SARS-CoV-2 and will continue to rapidly determine the threat levels posed by new variants. (cdc.gov)
But the virus has changed significantly since Wuhan-Hu-1 was sequenced in January 2020, with variants of concern ranging from Alpha to Omicron. (cdc.gov)
The current variants show that the virus is doing its best to make itself more suitable to ongoing circulation within the human population. (bvsalud.org)

Our protein products do not contain carrier protein or other additives (such as bovine serum albumin (BSA), human serum albumin (HSA) and sucrose, etc., and when lyophilized with the solution with the lowest salt content, they often cannot form A white grid structure, but a small amount of protein is deposited in the tube during the freeze-drying process, forming a thin or invisible transparent protein layer. (betalifesci.com)
2005). A comprehensive radiation hybrid map of the bovine genome comprising 5593 loci. (geneticsmr.com)

To facilitate systems biology in these traditionally agricultural species we have established "AgBase", a curated, web-accessible, public resource http://www.agbase.msstate.edu for structural and functional annotation of agricultural genomes. (biomedcentral.com)
We use experimental data to improve structural annotation of genomes and to functionally characterize gene products. (biomedcentral.com)
The BioProject database is a searcheable collection of complete and incomplete (in-progress) large-scale molecular projects including genome sequencing and assembly, transcriptome, metagenomic, annotation, expression and mapping projects. (nih.gov)

It is also called nucleotide sequence. (lookformedical.com)
Format of DAD entries The standard format of DAD is almost the same as that of the DDBJ nucleotide sequence database except for those described below. (nig.ac.jp)

Furthermore, other near-human species such as Zeltron, Chiss , and Sullustan share the human ortholog of this locus, which supports the inference that the ancestral sequence was noncoding, and that the GLABR has de novo origins in the Wookiee. (ubc.ca)
As Wookiees are a humanoid species, we postulate that when an all-against-all comparison is done with the Wookiee wookiee and Homo Sapien genomes, a portion of the Wookie genome will be distinct. (ubc.ca)
Otherwise, the absence of the phenotypic characteristics of plausible orthologs was attributed to the theorized inactivation within the genomes of other humanoid species. (ubc.ca)
Many agricultural species and their pathogens have sequenced genomes and more are in progress. (biomedcentral.com)
DEFINITION line contains species name and protein name. (nig.ac.jp)

New insights into the genome have led to the emergence of proteomics , the study of the structure and function of an individual's entire set of expressed proteins. (cdc.gov)
Some challenges for translating proteomics include technical issues in measuring proteomic markers, identifying clinically useful markers in patient samples, the need for large sample sizes to be able to distinguish protein variability among samples, and challenges in implementing strict protocols for sample handling. (cdc.gov)

2010). Genome wide scan for quantitative trait loci affecting tick resistance in cattle (Bos taurus x Bos indicus). (geneticsmr.com)
The resulting second generation is phenotyped and genotyped for DNA markers covering the genome so that linkage analysis can be performed and loci identified. (biomedcentral.com)
However, in the mid 1990s, other proteins were also found to accumulate in the abnormal muscle fibers, and molecular genetic studies revealed several chromosomal loci. (medscape.com)

In 2014, scientists developed a draft map of the human proteome , which catalogued proteins encoded by over 17,000 human genes, or about 84% of all protein-coding genes in the human genome. (cdc.gov)

SPRN comprises two exons, with the open reading frame (ORF) contained within exon 2, and codes for a protein of 130-150 amino acids named Shadoo (Japanese shadow), predicted to be extracellular and GPI-anchored. (nih.gov)
The chromosomal locations and number of exons from protein prenyltransferase genes in the major eukaryotic model organisms are shown in Table 2 . (biomedcentral.com)
Current genome assemblies have several thousands of gaps, causing bad gene model predictions due to missing exons and splice sites. (biomedcentral.com)
Sequences of DNA in the genes that are located between the EXONS. (lookformedical.com)

Sequence homology is an indication of the genetic relatedness of different organisms and gene function. (lookformedical.com)

The α subunits of protein prenyltransferases consist of tetratricopeptide repeats and are part of the tetratricopeptide repeat superfamily [ 5 ], which also includes functionally diverse proteins involved in transcription, co-chaperoning, protein transport, cell-cycle control and phosphorylation. (biomedcentral.com)
We use standardized nomenclature following the Human Genome Organization Gene Nomenclature guidelines and are currently functionally annotating chicken, cow and sheep gene products using the Gene Ontology (GO). (biomedcentral.com)

For his vision in using expressed sequence tags in genetic analyses, his unique contributions to the sequencing of microbial genomes, and his leadership in mobilizing new methods and resources for sequencing the human genome. (nasonline.org)
The phylogenetics, functional domain and protein-protein interaction analyses suggest an immunological role for Bg TEP in B. glabrata . (ac.ir)

Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. (nih.gov)
A polymorphism (rs2535629) of ITIH3 showed the strongest association signal with susceptibility to psychiatric disorders in Caucasian populations.Common single nucleotide polymorphisms (SNPs) in or near the inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) gene have been repeatedly associated with schizophrenia and related psychiatric disorders in genome-wide association studies.ITIH3 may be a useful biomarker for early detection of gastric cancer. (betalifesci.com)
The QIA express System provides materials for the expression, purification, detection and assay of 6xHis-tagged proteins. (qiagen.com)

There is paucity of information on functional relationship and characterization of Biomphalaria glabrata thioester-containing proteins ( Bg TEP) to other well-annotated homologues. (ac.ir)
1998). Isolation and characterization of human cathepsin V: a major proteinase in corneal epithelium. (geneticsmr.com)

2001). Remodeling of yeast genome expression in response to environmental changes. (geneticsmr.com)

Expressed sequence tag (EST) analysis and developmental polymerase chain reaction (PCR) studies demonstrated that Ov-phy-1 was expressed in L3 and adult parasites. (embl.de)
High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. (genscript.com)
Acts as a cofactor to stimulate the activity of 3D polymerase, maybe through a nucleid acid chaperone activity .Protein 3A: Localizes the viral replication complex to the surface of mbranous vesicles. (enquirebio.com)
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. (lookformedical.com)
Highly repeated sequences, 100-300 bases long, which contain RNA polymerase III promoters. (lookformedical.com)

This database has been produced by extracting all translated sequences from conventional sequence data of DDBJ periodical release 121.0 and TPA data set (August 2020). (nig.ac.jp)

The genes encoding these proteins are highly conserved within the Trichinellids, are constituents of mL1 ESP and localized in the parasite stichosome. (westminster.ac.uk)

Through cloning of functional p53-binding sites (p53-tagged sites) from the human genome, we isolated a novel gene inducible by wild-type p53. (aacrjournals.org)
You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. (betalifesci.com)
Bg TEP relatedness to its other homologues as well as functional domain and protein-protein interaction analysis was performed. (ac.ir)

It is recommended to use for co-immunoprecipitation and protein purification. (nfkbcell.com)

The recombinant human consists 869 a.a. and predicts a molecular mass of 97.7 kDa. (betalifesci.com)
The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. (betalifesci.com)
How to properly dissolve lyophilized recombinant proteins? (betalifesci.com)

Genes contributing to the similarity include ribosomal protein (RP) genes as well as genes involved in transcription, translation and cell division. (karger.com)
The extracellular sequences of RON contain several domains including an N-terminal semaphorin (sema) domain, followed by the plexin, semaphorin, integrin (PSI) domain, and four immunoglobulin, plexin, transcription factor (IPT) domains. (spandidos-publications.com)
Conserved transcription factor-binding sites within promoter regions of human RON genes were then searched. (spandidos-publications.com)
Transcription activator-like effectors (TALEs) are DNA major-groove binding proteins widely used for genome targeting. (nature.com)
The region of DNA which borders the 3' end of a transcription unit and where a variety of regulatory sequences are located. (lookformedical.com)
Nucleotide sequences, usually upstream, which are recognized by specific regulatory transcription factors, thereby causing gene response to various regulatory agents. (lookformedical.com)

Using a fluorescent sulfhydryl probe as well as a sulfhydryl inhibitor, one observes a strong cell density response, supporting the hypothesis that cellular redox potential could alter protein stability. (embl.de)
By sequencing these tags alongside the cellular transcriptome, we can assign each cell to its original sample, robustly identify cross-sample multiplets, and "super-load" commercial droplet-based systems for significant cost reduction. (nih.gov)
When a cell is perturbed, it responds by altering expressing levels of specific proteins and adjusting cellular functions in response to the new environmental stimuli. (cdc.gov)
Limb-girdle muscular dystrophy (LGMD) protein defects occur in several pathways involved in the biologic function of muscle and can be divided into groups based on cellular localization. (medscape.com)

The Assembly resource provides access to genome assemblies for both submitted data and NCBI RefSeq assemblies. (nih.gov)

ORF sequences can be delivered in our standard vector, pcDNA3.1 + /C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. (genscript.com)
The molecular sequence of this clone aligns with the gene accession number as a point of reference only. (origene.com)
This clone was engineered to express the complete ORF with an expression tag. (origene.com)

Bortoluzzi S, Alessi FD, Romualdi C, Danieli GA: Differential expression of genes coding for ribosomal proteins in different human tissues. (karger.com)
Co-expression of Ov-phy-1 with the O. volvulus homologue of protein disulfide isomerase in a baculovirus system resulted in the production of enzymatically active O. volvulus prolyl 4-hydroxylase. (embl.de)
This gene has no protein-coding homolog in any other genome but its presence is supported by evidence from expression and hybridization data. (ubc.ca)
Although we detected no genetic alteration in the coding sequences, one of four rhabdomyosarcoma cell lines examined had completely lost expression of this gene. (aacrjournals.org)
The localization of the HKE2 gene to the class II region, its cytoplasmic expression and putative protein-binding domain suggest that HKE2 may function in adaptive immunity and cancer. (genscript.com)
Distribution of CD44 variant isoforms in human skin: differential expression in components of benign and malignant epithelia. (geneticsmr.com)

BioSystems currently contains biological pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) and the EcoCyc ( Escherichia coli K-12 MG1655) subset of the BioCyc databases and is designed to accommodate other data in the future. (nih.gov)
Whole-genome studies have provided a useful insight into how gene patterns may influence the development and/or progression of certain pathological pathways, including fibrosis [ 2 ]. (biomedcentral.com)

Inhibits the host nucleus-cytoplasm protein and RNA trafficking by cleaving host mbers of the nuclear pores .Protein 2B: Plays an essential role in the virus replication cycle by acting as a viroporin. (enquirebio.com)

Livestock genomes will always have low build numbers compared with model organisms such as human and mouse and yet they have comparable numbers of genes (UniGene). (biomedcentral.com)

The Most cancers Genome Atlas (TCGA) pilot undertaking goals to evaluate the worth of large-scale multi-dimensional evaluation of those molecular traits in human most cancers and to present the info quickly to the analysis neighborhood. (nfkbcell.com)
Northern blot analysis showed that it was expressed predominantly in skeletal muscle. (aacrjournals.org)
Transcriptome analysis of human gastric cancer. (genscript.com)
In addition, TEP sequences deposited in NCBI protein database were also retrieved and utilized for sequence analysis. (ac.ir)
EU COST Next generation sequencing data analysis network and training consortium. (mpg.de)
Genome sequencing on the Oxford Nanopore platform was performed using the ARTIC approaches for library preparation and bioinformatic analysis. (cdc.gov)

Conserved Domains is a database of protein domains represented by sequence alignments and profiles for protein domains conserved in molecular evolution. (nih.gov)

RON is activated in response to macrophage-stimulating protein (MSP), and then induces an invasive program ( 8 ) consisting of cell proliferation, migration, and invasion, all of which are important at multiple points during tumorigenesis. (spandidos-publications.com)

To begin, we hypothesize that distinct morphological features, in other words, hairiness are a result of Wookiee specific protein-coding gene(s). (ubc.ca)
Estrogen withdrawal or treatment with the established anticancer drug doxorubicin cause the methyl groups to be removed from regulatory regions of specific genes within tens of minutes in human breast cancer cells. (sciencedaily.com)
Allows the capsid to rain inactive before the maturation step .Protein 2A: Cysteine protease that cleaves viral polyprotein and specific host proteins. (enquirebio.com)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
Specific signal sequences, AREs for example[ 17 ], can affect the rate at which the poly-adenosine tail is shortened. (berkeley.edu)
The long term goal of our research is to elucidate the molecular mechanisms by which proteins are targeted to specific and distinct compartments. (stanford.edu)
Such mouse strain studies may prove useful in elucidating the genetic as well as epigenetic factors in humans that could help determine why some people are more susceptible to the development of certain organ specific fibrosis than others. (biomedcentral.com)
Specific protein function and abnormalities are discussed below with each LGMD. (medscape.com)
check also tag CHILD or specific HN - 2008 FX - Adolescent Nutrition FX - Infant Nutrition DH - Maternal Nutrition DI - 052505 MN - SP6.021.072 MS - Nutrition of a mother which affects the health of the INFANT as well as herself. (bvsalud.org)

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (genscript.com)

Hence, we designated the gene P2XM ( P2X specifically expressed in skeletal muscle). (aacrjournals.org)
Trichinella spiralis muscle stage larvae (mL1) produce excretory-secreted products (ESPs), a complex mixture of protein, which are believed to be important for establishing or maintaining an infection niche within skeletal muscle and the intestine. (westminster.ac.uk)

In transfected HEK293 transiently expressing full-length Human PHLDA3 (myc and DYKDDDDK tagged), a band of approx. (prosci-inc.com)

Recent advances in sequencing technology make it possible to comprehensively catalog genetic variation in population samples, creating a foundation for understanding human disease, ancestry and evolution. (nordiag.com)

For leading the development of multiple antibiotics, vitamin B12, and the avermectins, the latter revolutionizing parasite treatment in livestock and humans. (nasonline.org)

The amino acid sequence of one representative TALE repeat is shown on top, with RVD amino acids 12 and 13 marked with a grey box and KQ diresidue at positions 16 and 17 involved in DNA phosphate binding in bold and underlined. (nature.com)
Amino acid sequence of the N-terminal region (NTR) is shown on the bottom with amino acids suspected to be involved in DNA phosphate binding in bold and underlined. (nature.com)

A Global Ethics Council consisting of independent scientists as well as a representative cross section of civil society should be established as a matter of urgency to deal with these gross violations of human rights, privacy and dignity. (i-sis.org.uk)
The scientists used a genome-wide mapping technique to finally see the wiring between the lights and switches. (ddw-online.com)
This track was produced at UCSC from EST sequence data submitted to the international public sequence databases by scientists worldwide. (noncode.org)
Studies of the human proteome have enabled scientists to track protein synthesis, modification, and degradation over time and across different cell types. (cdc.gov)
Because the proteome is a continuously changing set of proteins that differs from cell to cell, it is challenging for scientists to capture and study it. (cdc.gov)
This year, scientists released a more complete map of the human proteome estimated to include more than 90% of the human proteome. (cdc.gov)

Description: Protein A/G Magnetic Beads for immunoprecipitation (IP) are based on a biological nanosurface technology (S-TEC). (nfkbcell.com)
The life cycle of a protein starts with a blueprint transcribed from a gene, followed by folding, which translates the blueprint to a three-dimensional structure that allows it to carry out its biological function, and ends with degradation. (cdc.gov)

Gene structures and chromosomal locations of human protein prenyltransferase subunit genes. (biomedcentral.com)
Human most cancers cells usually harbour a number of chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation. (nfkbcell.com)

Genome Res 7:986-995 (1997). (karger.com)
1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. (geneticsmr.com)

Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. (origene.com)

The derived amino acid sequence of Ov-phy-1 encoded a peptide that was most similar to the two Caenorhabditis elegans prolyl 4-hydroxylase homologues and to the isoform II enzymes of vertebrates. (embl.de)
These include proteins associated with the sarcolemma (see image below), proteins associated with the contractile apparatus (see image below), and various enzymes involved in muscle function. (medscape.com)

DDBJ Amino Acid Sequence Database (DAD) Release 91.0, Sep. (nig.ac.jp)
Introduction This is release 91.0 of DDBJ Amino Acid Sequence Database (DAD). (nig.ac.jp)
When citing an entry in the DAD database, it is appropriate to give the protein_id and its accession number. (nig.ac.jp)

A framework for variation discovery and genotyping using next-generation DNA sequencing data. (nordiag.com)
3. DAD categories DAD entries are classified into 23 categories, adding TPA and TPACON to the 21 divisions of conventional sequence data of DDBJ periodical release. (nig.ac.jp)
DDBJ also makes no legal liability or responsibility of merchantability or fitness for a particular purpose or that the use of the sequence data will not infringe any patent or other rights. (nig.ac.jp)

Anatomy15

Organisms42

Diseases3

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Phenomena and Processes111

Disciplines and Occupations5

Technology, Industry, Agriculture6

Information Science15

Health Care4

Genomic14

Antibody10

CDNA4

Antibodies4

Genomics2

ESTs7

19991

Mammalian3

Viral genome3

Gene Expression8

20021

MRNA8

Introns2

Mice4

Variants9

Bovine2

Annotation3

Nucleotide sequence2

Species5

Proteomics2

Loci3

Genes in the human1

Exons4

Homology1

Functionally2

Analyses2

Detection3

Characterization2

Yeast1

Polymerase5

20201

Highly conserved1

Functional3

Purification1

Recombinant3

Transcription6

Cellular4

RefSeq1

Clone3

Expression6

Pathways2

Cytoplasm1

Organisms1

Analysis6

Alignments1

Induces1

Specific9

Tissues1

Skeletal muscle2

HEK2931

Genetic variation1

Livestock1

Amino acids2

Scientists6

Biological2

Chromosomal2

19972

Alignment1

Enzymes2

Database3

Data3