DNA DamageDNA RepairComet AssayAtaxia Telangiectasia Mutated ProteinsCell Cycle ProteinsUltraviolet RaysDeoxyguanosineCheckpoint Kinase 2Tumor Suppressor Protein p53DNA-Binding ProteinsProtein-Serine-Threonine KinasesDNA Breaks, Double-StrandedOxidative StressCell CycleTumor Suppressor ProteinsGamma RaysApoptosisDNAMethyl MethanesulfonateHistonesMutagensNuclear ProteinsGenomic InstabilityMutationG2 PhaseDNA ReplicationPhosphorylationCell Line, TumorCell LineDose-Response Relationship, RadiationDNA AdductsDNA Repair EnzymesCell SurvivalReactive Oxygen SpeciesHydrogen PeroxideSignal TransductionDNA BreaksProtein KinasesRadiation TolerancePoly(ADP-ribose) PolymerasesGenes, cdcCell Cycle CheckpointsDNA Breaks, Single-StrandedHeLa CellsCells, CulturedRad51 RecombinaseTime FactorsDNA GlycosylasesMolecular Sequence DataSaccharomyces cerevisiae ProteinsS PhaseFibroblastsBRCA1 ProteinModels, BiologicalMitosisMicronucleus TestsSaccharomyces cerevisiaeCell AgingAntioxidantsCell NucleusHydroxyureaIntracellular Signaling Peptides and ProteinsProtein BindingChromatinAlkylating AgentsDNA-Activated Protein KinaseG2 Phase Cell Cycle CheckpointsX-RaysDose-Response Relationship, DrugOxidation-ReductionReplication Protein ABase SequenceRecombinational DNA RepairCell DeathRecombination, GeneticDNA HelicasesRNA, Small InterferingMice, KnockoutDisease Models, AnimalMice, Inbred C57BLPoly Adenosine Diphosphate RiboseBlotting, WesternProto-Oncogene Proteins c-mdm2SOS Response (Genetics)Micronuclei, Chromosome-DefectivePyrimidine DimersTelomereAmino Acid SequenceMitomycinDNA-Formamidopyrimidine GlycosylaseLymphocytesUbiquitinationHCT116 CellsMutagenicity TestsCyclin-Dependent Kinase Inhibitor p21CarcinogensGuanineGene Expression RegulationNucleic Acid Synthesis InhibitorsDNA, Fungal