Humans disease in dogs usually affects choroid diseases. Medical search. Frequent questions

There are a many diseases which can affect the retina. (vetsci.co.uk)
Collie eye anomaly (CEA) - a congenital, inherited, bilateral eye disease of dogs involving the retina, choroid, and sclera. (vetsci.co.uk)
Over 200 mutations in the retina specific member of the ATP-binding cassette transporter superfamily (ABCA4) have been associated with a diverse group of human retinal diseases. (upenn.edu)
Immunocytochemistry of normal canine retina demonstrated specific localization of protein to the RPE basolateral plasma membranes. (upenn.edu)
therefore, the optic nerve must cross through the retina en route to the brain. (wikipedia.org)
[9] Some vertebrates, including humans, have an area of the central retina adapted for high-acuity vision. (wikipedia.org)
The ocular fundus is the back of the eye opposite the pupil and includes the retina, the membrane (the choroid) between the retina and the white of the eye, and the optic disk. (merckvetmanual.com)
Inherited abnormalities may be present at birth or appear later, and are important in the development of diseases of the retina in dogs. (merckvetmanual.com)
The main abnormality is an area of the choroid or the retina and choroid that fails to develop fully. (merckvetmanual.com)
More severely affected dogs may also have abnormalities close to where the optic nerve enters the eye, and some will have detachment of the retina. (merckvetmanual.com)
Vision is not noticeably affected unless detachment of the retina is present. (merckvetmanual.com)
In dogs, the cause most often is a disease-related accumulation of fluid underneath the retina that separates it from the choroid. (furrycritter.com)
Therapy must be instituted as early in the disease process as possible, or the detached retina will deteriorate and the dog will be permanently blind. (furrycritter.com)

When the iris, by itself or together with the ciliary body, is affected, this is called anterior uveitis. (topeyedoctorsnearme.com)
Intermediate uveitis means the ciliary body only is affected. (topeyedoctorsnearme.com)

In the brain, iodine is found in the choroid plexus, the area on the ventricles of the brain where cerebrospinal fluid (CSF) is produced, and in the substantia nigra, an area associated with Parkinson's disease. (westonaprice.org)
Intraventricular hemorrhage (IVH) and post-hemorrhagic hydrocephalus (PHH) have complex pathophysiology involving inflammatory response, ventricular zone and cell-cell junction disruption, and choroid-plexus (ChP) hypersecretion. (researchsquare.com)
PHH is a complex condition that involves neuro-inflammation (8), alterations in ventricular zone (VZ) junctional biology (10-14), and choroid plexus (ChP) hypersecretion (15), among other processes. (researchsquare.com)

Its outer surface is in contact with the choroid and the inner surface with the vitreous body. (lecturio.com)

The hormone insulin is recognized as having actions that affect the trans-membrane transport of different substances, particularly glucose, into numerous different kinds of cells. (weeksmd.com)
Bioactive sphingolipids in health and disease: lipidomic analysis, metabolism and roles in membrane signaling and autophagy. (sphingolipidclub.com)

Abstract- The Human Immunodeficiency Virus (HIV) is the causative agent of AIDS and this has been found to be neurotropic. (weeksmd.com)
Pretreatment Human Immunodeficiency Virus (HIV) Drug Resistance Among Treatment-Naive Infants Newly Diagnosed With HIV in 2016 in Namibia: Results of a Nationally Representative Study. (cdc.gov)

Standardization of canine meningioma grading: Validation of new guidelines for reproducible histopathologic criteria. (unibe.ch)

Posterior uveitis is the term used when the choroid is the affected area. (topeyedoctorsnearme.com)

Canine multifocal retinopathy (cmr) is an autosomal recessive disorder of multiple dog breeds. (upenn.edu)
However, the study did find improvements to microvascular conditions, such as progression of diabetic eye disease (retinopathy), visual acuity, and renal and nerve function. (monroecountyfl.org)

Hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum (HMSN/ACC) is an autosomal recessive disease of the central and peripheral nervous system that presents as early-onset polyneuropathy. (nature.com)

Systemic diseases such as sarcoidosis Sarcoidosis Sarcoidosis is a multisystem inflammatory disease that causes noncaseating granulomas. (lecturio.com)

Felines are the definitive host, but transmission to humans can occur through contact with cat feces or the consumption of contaminated foods. (lecturio.com)
Diseases of the ocular fundus may occur on their own or as a part of generalized diseases. (merckvetmanual.com)
Detached retinas can occur at any age and can affect one or both eyes, depending upon the underlying cause. (furrycritter.com)

The molecules acting through RAS predominantly ARBs and ACEI are found to be effective in various ongoing and completed clinical trials related to cognition, memory, Alzheimer's disease (AD), and pain. (hindawi.com)

Chronic Granulomatous Disease can affect the fetus in utero and present as congenital abnormalities Congenital Abnormalities Malformations of organs or body parts during development in utero. (lecturio.com)
Although CMV is the most common congenital infection in the developed world, affecting approximately 1% of all infants born in the United States, only 10% of all infants born in the United States with congenital CMV infection have symptomatic disease at birth, including chorioretinitis. (medscape.com)

As orthologous genes are commonly mutated in canine models of human blinding disorders, canine ABCA4 appears to be an ideal candidate gene to identify and study sequence changes in dogs affected by various forms of inherited retinal degeneration. (upenn.edu)
Purpose: Mutations in bestrophin 1 (BEST1) are associated with a group of retinal disorders known as bestrophinopathies in man and canine multifocal retinopathies (cmr) in the dog. (upenn.edu)
In addition, with increasing air travel and globalization, several emerging infectious diseases have been recognized as causing ocular disease, including retinitis, chorioretinitis, retinal vasculitis, and optic nerve involvement. (medscape.com)
Most forms of retinal dysplasia in dogs are inherited. (merckvetmanual.com)
Viral infections of the mother (for example, herpesvirus in dogs), especially during early fetal development, can result in many eye abnormalities with retinal dysplasia in puppies. (merckvetmanual.com)

Expression of the canine gene transcripts and protein was analyzed by Northern and Western blotting and immunocytochemistry. (upenn.edu)
In the present study we examined the relationship between ceramide, ceramide metabolites and expression of the MDR1 gene in human breast cancer cell lines. (sphingolipidclub.com)
Exposure of cells to either octanoic acid (C8:0), a C8-ceramide hydrolysis product, or oleic acid (C18:1) did not affect MDR1 expression. (sphingolipidclub.com)

While none of the observed polymorphisms have been associated with blinding disorders to date, breed and potentially disease specific haplotypes have been identified. (upenn.edu)
Our sequence analysis of the complete canine ABCA4 coding region will clearly provide a baseline and tools for future association studies and comparative genomics to further delineate the role of ABCA4 in canine blinding disorders. (upenn.edu)

Thus, in future, molecular studies on the cellular host-pathogen interaction, considering physiologic and pathophysiologic oxygen conditions, can be used to characterize adequately new therapeutic target structures against infectious diseases in humans and animals. (biomedcentral.com)
CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)

COMMISSIONED PAPER (UK) This paper was commissioned by FECAVA for the Special issue of EJCAP, Genetic/Hereditary Disease and Breeding. (marysfamilymedicine.org)
The hereditary disease, whose causative mutation in the MYO5A gene is detected with the test, was initially called Griscelli type 1 analogue syndrome because of the analogy in humans. (generatio.de)

BEST1 (alias VMD2), the bestrophin gene causally associated with BMD, was evaluated in the dog. (upenn.edu)
Two disease-specific sequence alterations were identified in the canine VMD2 gene: a C73T stop mutation in cmr1 and a G482A missense mutation in cmr2. (upenn.edu)
The authors propose these two spontaneous mutations in the canine VMD2 gene, which cause cmr, as the first naturally occurring animal model of BMD. (upenn.edu)
These markers are thought to be related to "domestication gene sweeps" where early dogs were selected for some trait. (embarkvet.com)
Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. (fundacionareces.es)

Centers for Disease Control and Prevention. (cdc.gov)
To address the rapid decline in hypertension control, the National Heart, Lung, and Blood Institute and the Division for Heart Disease and Stroke Prevention of the Centers for Disease Control and Prevention convened a virtual workshop with multidisciplinary national experts. (cdc.gov)

Most canine meningiomas are adjacent to the calvarium and a significant number of these tumors involve the olfactory/frontal region, the floor of the cranial cavity, the optic chiasm or the suprasellar and parasellar regions. (hallmarq.net)

We conclude that the neurodegenerative deficits in HMSN/ACC are primarily caused by an axonopathy superimposed upon abnormal development, affecting peripheral but also central nervous system axons, all ultimately because of a genetic defect in the axonal cotransporter KCC3. (nature.com)

Despite being a neurodegenerative disease, preservation of brain weight and a conspicuous absence of neuronal or glial cell death were signal features of this disease. (nature.com)
Neither the significance nor the causes of the variable involvement of the corpus callosum are known, but it is not correlated to the natural course of the disease and the neurodegenerative features of HMSN/ACC, which do not vary significantly between individuals with or without ACC. (nature.com)

Neurological dysfunction is a leading cause of disability, affecting more than 276 million people worldwide.1 Over the last decades, the prevalence of neurological dysfunction. (annals.edu.sg)
Migraine is the most common neurological disorder, affecting 18% of females and 6% of males, with prevalence peaking at age 30-40 years. (frontiersin.org)
The owner was also concerned about the possibility of the dog having neck pain although a neurological examination was considered normal at the time of presentation. (hallmarq.net)

We here define the neuropathologic features of the disease in autopsy tissues from eight cases. (nature.com)
Its actions on liver, adipose tissue, and skeletal muscle have all been studied in great detail, and it is now recognized that insulin also affects a wide variety of tissues in addition to just these three. (weeksmd.com)

An injury to the eye or face can create a detachment, as can tumors and diseases like diabetes, high blood pressure, lupus, kidney disease and sickle cell anemia. (furrycritter.com)

We then factor in your dog's breed composition, information at certain genes that affect size, and their inbreeding coefficient to calculate genetic age. (embarkvet.com)

During infection and inflammation, a reduced oxygen level clearly affects cellular functions. (biomedcentral.com)
A decrease in oxygen supply in case of infection and inflammation can influence the host-pathogen interaction as well as pathogenesis of various diseases [ 1 , 2 , 3 ]. (biomedcentral.com)

Choroid - Darkly pigmented to prevent light escaping the eye, it contains blood vessels which supply all the internal structures of the eyeball. (vetsci.co.uk)

The disease shares a number of clinical and pathologic similarities with Best macular dystrophy (BMD), and cmr is proposed as a new large animal model for Best disease. (upenn.edu)
Beyond the neonatal period, chorioretinitis can be diagnosed in diverse clinical conditions and can reflect newly acquired diseases or reactivation. (medscape.com)
There are multiple clinical presentations: 1) leukoencephalomyelitis, affecting 2- to 6-month-old kids, 2) chronic, hyperplastic polysynovitis, 3) indurative mastitis, and 4) interstitial pneumonia. (merckvetmanual.com)
however, a positive result does not guarantee an individual animal will develop clinical signs of disease. (merckvetmanual.com)

This lesion causes moderate perilesional oedema which tracks along the white matter to reach the rostral occipital lobe, and causes mild mass effect, with mild midline shift. (hallmarq.net)

This is a rare, zoonotic roundworm infection passed from domestic pets to humans through feces. (topeyedoctorsnearme.com)

Sarcoidosis usually affects the lungs and thoracic lymph nodes, but it can also affect almost every system in the body, including the skin, heart, and eyes, most commonly. (lecturio.com)
Although the dural tail feature is commonly associated with meningiomas, it is not specific for this tumor type, or for neoplastic diseases in general. (hallmarq.net)
The condition most commonly affects people 20 to 60 years of age and does not affect one sex more than the other. (topeyedoctorsnearme.com)

Increased cerebrospinal fluid (CSF) cytokines, extracellular matrix proteins, and blood metabolites have been noted in IVH/PHH, but osmolality and electrolyte disturbances have not been evaluated in human infants with these conditions. (researchsquare.com)
However, only a limited number of studies have examined the biochemical profile of CSF in hydrocephalus (32, 33), and no studies have reported these in PHH in human preterm infants to date. (researchsquare.com)

Khazal, K. F., Hill, D. L. und Grubbs, C. J.: Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice. (natur-wiki.de)

However, the specific effect of PL in cervical cancer and the relationship between the anti-cancer pathway and autophagy remain unclear. (bvsalud.org)
Therefore, we aimed to investigate PL-induced apoptosis in KB human cervical cancer cells and the relationship between apoptosis and autophagy therein. (bvsalud.org)

Since there is insufficient knowledge about physiologic and pathophysiologic oxygen levels in humans and animals, in vivo characterization is necessary to optimize conditions for in vitro studies and therefore finally to reduce the number of animal experiments. (biomedcentral.com)

The farmers in the area took this imported dog and bred him with local dogs to create the Bearded Collie. (poodlemixclub.com)
Your Bearded Collie Poodle mix may develop any number of distinct appearances as it matures, just as this is the case with any other type of mixed-breed dog. (poodlemixclub.com)

For example humans have a globe shaped eyeball, whereas horses have a non-spherical, almost cuboidal eyeball. (vetsci.co.uk)

Ensure young children do not inadvertently handle or play with dog feces. (topeyedoctorsnearme.com)
Teach older children how to clean up dog feces properly and always wash hands afterward. (topeyedoctorsnearme.com)

It can be a mild disease or cause blindness. (vetsci.co.uk)

Like in humans, in dogs females tend to live longer than males (so an "80 year old" female dog = 80 year old woman). (embarkvet.com)

The search for more effective therapies to treat disease has traditionally focused on the development of new drugs. (weeksmd.com)

Concentrations and kinetics of renal biomarkers in dogs with gastric dilatation-volvulus with and without 24-h intravenous lidocaine. (unibe.ch)

A genetic test is available to confirm the presence of the disease or identify carrier dogs that could pass the disease to their puppies. (merckvetmanual.com)
The genetic age in this report is an estimation of where your dog is in his or her healthspan. (embarkvet.com)
Dogs age at very different rates due to a number of genetic and environmental factors. (embarkvet.com)
Embark's genetic age feature calculates how old your dog would be if he or she were aging at an average human rate (using humans in the USA as the baseline). (embarkvet.com)
Instead, the Wolfiness Score is based on the number of ancient genetic variants your dog has in our unique Wolfiness marker panel. (embarkvet.com)
But genetic weight is also useful for people with fully grown dogs. (embarkvet.com)

The condition is usually caused by infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. (lecturio.com)
Some of these infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. (lecturio.com)
PPRV-induced immunosuppression may predispose affected animals to secondary infections ( 3 , 9 ) as reflected by distinct severe leukocytopenia in pigs and goats a few days after inoculation. (cdc.gov)

Humans have round pupils, whereas cats for example have pupils shaped as vertical slits. (vetsci.co.uk)
In dogs, meningiomas have a tendency to infiltrate into the brain tissue but in cats, meningiomas are often well encapsulated. (hallmarq.net)
Even then, the disease can be easily avoided, and there is no need to fear domestic cats because of toxoplasmosis. (topeyedoctorsnearme.com)
The presence or absence of physiologic spaces between primary teeth was noted, as was the presence or absence of primate spaces spaces mesial to maxillary canine and distal to mandibular primary download free hack pubg manifestations along with the molecular analysis support the assumption that domestic cats might be infected with and serve as a reservoir host for Cytauxzoon sp. (celebralotodo.com)

And yet, knowing your dog's age is important: it informs what your dog needs as far as food, frequency of veterinary checkups, and exercise. (embarkvet.com)
It can help you and your vet know what you should feed your dog, what screenings to get, and other aspects of your dog's care. (embarkvet.com)
Your dog's Wolfiness Score is not a measure of recent dog-wolf hybridization and does not necessarily indicate that your dog has some recent wolf ancestors. (embarkvet.com)
Your dog's Wolfiness Score is based on hundreds of markers across the genome where dogs (or almost all of them) are the same, but wolves tend to be different. (embarkvet.com)

Since the increase in availability of magnetic resonance imaging (MRI), syringomyelia is an increasingly common diagnosis in veterinary medicine (1, 2) The most common cause of syringomyelia in the dog is Chiari-like malformation (Fig 1), a condition analogous to Chiari Type I and 0 malformation in humans (3, 4). (marysfamilymedicine.org)
However this theory also leaves many unanswered questions and further study is In the dog syringomyelia is associated with a number of different pathologies with a common theme of CSF flow obstruction. (marysfamilymedicine.org)
Although dogs of solid colors exist, it is more common to find dogs with patches and markings, particularly on the face and chest. (poodlemixclub.com)
Migraine is a common, little understood, and debilitating disease. (frontiersin.org)
Common migraine comorbidities affect multiple organ systems in addition to the CNS ( 1 ). (frontiersin.org)
The most common side effect of a scleral operation is myopic shift. (furrycritter.com)
In dogs, the term 'Colour Dilution Neuropathy' (CDN) has become common as well. (generatio.de)

The Roles of the 5' and 3' Untranslated Regions in Human Astrovirus Replication. (unibe.ch)
It forms the basis of thyroid hormones and plays many other roles in human biochemistry. (westonaprice.org)

MRI ischemic and hemorrhagic lesions in arterial and venous territories characterize central nervous system intravascular lymphoma in dogs. (unibe.ch)

LRP6 Is a Functional Receptor for Attenuated Canine Distemper Virus. (unibe.ch)
Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. (unibe.ch)

Pingali, U., Pilli, R. und Fatima, N.: Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants. (natur-wiki.de)

Machine learning predicts histologic type and grade of canine gliomas based on MRI texture analysis. (unibe.ch)
They emphasized that both the positive and negative results of the study apply only to this population of middle-aged or older people with type 2 diabetes for an average of 10 years, who also had a history of cardiovascular disease (CVD) or at least two risk factors for CVD. (monroecountyfl.org)
Anwer, T. et al: Protective effect of Withania somnifera against oxidative stress and pancreatic beta-cell damage in type 2 diabetic rats. (natur-wiki.de)
(See also Chap. 148 ) After a peak of 57,879 cases of poliomyelitis in the United States in 1952, the introduction of IPV in 1955 and of OPV in 1961 ultimately eradicated disease due to wild-type poliovirus in the Western Hemisphere. (basicmedicalkey.com)
Four wild-type (drug-sensitive) human breast cancer cell lines (MCF-7, T47D,MDA-MB-231, MDA-MB-435) were used to evaluate the influence of acute and chronic exposure to ceramide and ceramide metabolites on MDR1 mRNA,P-gp, and resistance to chemotherapeutic agents. (sphingolipidclub.com)

It is a symptom rather than a specific disease and is associated with a variety of conditions. (livs.org)

Syringomyelia is a disorder of CSF and therefore understanding the pathogenesis of this enigmatic disorder is dependent on understanding CSF flow dynamics, biochemistry and factors that influence its absorption and The majority of CSF is produced by the four choroid plexuses (one in each ventricle of the brain), which circulates through the ventricular system and the subarachnoid spaces of the brain and spinal cord (9, 10). (marysfamilymedicine.org)
Otherwise considered healthy, the dog underwent a brain MRI using the Hallmarq 1.5T machine (see Figs 1 & 2). (hallmarq.net)

By finding rare dogs carrying an ancient variant at a certain marker, we can make associations with behavior, size, metabolism, and development that likely caused these unique signatures of "doggyness" in the genome. (embarkvet.com)

Most dogs are back to normal within a few days to a week. (livs.org)

AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)

The local farmers thought these dogs were so great that they were worth trading their sheep with the Polish sailors. (poodlemixclub.com)

An increasing incidence of eye diseases has been registered in the last decades in developed countries due to the ageing of population, changes in lifestyle, environmental factors, and the presence of concomitant medical conditions. (mdpi.com)

Anatomy11

Diseases6

Psychiatry and Psychology2

Phenomena and Processes3

Information Science1

Retina13

Ciliary body2

Plexus3

Vitreous1

Membrane2

Immunodeficiency Virus2

Standardization1

Posterior1

Retinopathy2

Autosomal recessive1

Systemic1

Occur3

Alzheimer's1

Congenital2

Retinal5

Expression3

Disorders2

Infectious3

Hereditary Disease2

Gene5

Centers2

Adjacent1

Abnormal development1

Neurodegenerative2

Neurological3

Tissues2

Kidney disease1

Genes1

Inflammation2

Structures1

Clinical4

Midline1

Infection1

Commonly3

Infants2

Spontaneous1

Cervical2

Optimize1

Collie2

Horses1

Feces2

Blindness1

Females1

Therapies1

Renal1

Genetic6

Infections3

Cats4

Dog's4

Common7

Roles2

Characterize1

Virus2

Cognitive1

Type5

Specific1

Brain2

Development1

Normal1

Syndrome1

Sheep1

Conditions1