• acute promyelo
  • In an accompanying commentary, Praveen Raju, at Weill Cornell Medical College, New York, notes that the data provide rationale for considering ATO as a therapy for cancers other than acute promyelocytic leukemia. (redorbit.com)
  • metabolites
  • This theory is further supported by a cross-sectional study which found elevated mean serum lipid peroxides (LPO) in the As exposed individuals which correlated with blood levels of inorganic arsenic and methylated metabolites and inversely correlated with nonprotein sulfhydryl (NPSH) levels in whole blood. (wikipedia.org)
  • soluble
  • Iron does test only very weakly positive for the Ames test for cancer, however, since it is such a strong catalyst and essential for the production of ATP and consequently DNA production, any excess soluble iron is toxic especially over time. (wikipedia.org)
  • Drinking Water
  • The principal treatment is to provide the patient with arsenic free drinking water. (bicn.com)
  • The Bangladesh Standard for arsenic in drinking water is 0.05 mg/l. (bicn.com)
  • Where drinking water is rusty colored and has arsenic, the rusty particles may concentrate the arsenic. (umass.edu)
  • To determine if arsenic is present, arrange to test your drinking water at a state certified laboratory. (umass.edu)
  • Now, drinking water is the villain in what CBS television once called 'the greatest poisoning in human history. (worldwatch.org)
  • Now, "the presence of arsenic in drinking water is becoming a widespread health problem," said Luis Rodriguez-Lado, a chemist with the University of Santiago de Compostela in Spain who was not involved in the study. (canadianinquirer.net)
  • For example, while workers were dying of chromium and benzene poisoning and whole populations were affected by arsenic in drinking water, animals in laboratories failed to show the same effects, so protective regulations were delayed. (reformer.com)
  • Through drinking water, more than 200 million people globally are exposed to higher than safe levels of arsenic. (wikipedia.org)
  • Inorganic arsenites (arsenic(III)) in drinking water have a much higher acute toxicity than organic arsenates (arsenic(V)). The acute minimal lethal dose of arsenic in adults is estimated to be 70 to 200 mg or 1 mg/kg/day. (wikipedia.org)
  • A 2007 study found that over 137 million people in more than 70 countries are probably affected by arsenic poisoning of drinking water. (wikipedia.org)
  • Bangladesh is the most affected country by arsenic poisoning through drinking water. (wikipedia.org)
  • Estimation of Arsenic Intake from Drinking Water and Food (Raw and Cooked) in a Rural Village of Northern Chile. (wikipedia.org)
  • However, with over 8 million wells constructed, approximately one in five of these wells is now contaminated with arsenic above the government's drinking water standard. (wikipedia.org)
  • Programmes to provide 'safe' drinking-water over the past 30 years have helped to control these diseases, but in some areas they have had the unexpected side-effect of exposing the population to another health problem-arsenic. (wikipedia.org)
  • 2017
  • A recent report (Science, 2017) Shows more the investigation of 1200 samples was carried out and approximately more than 66% samples contained arsenic above WHO recommended limit. (wikipedia.org)
  • unsafe
  • More than 60 percent of the wells in this subdistrict are contaminated with arsenic and unsafe to drink from,' explains Sayed Ershad, a development worker who has spent the last several years grappling with the disaster. (worldwatch.org)
  • Pakistan Council of Research in Water Resources (PCRWR) has released a report ( PDF link here ) which found 10 brands of bottled water unsafe for human consumption, with Butt Water somehow making that list. (webwire.com)
  • Yet this company, which borrows a concept meant to protect present and future generations from harm, has actively promoted chemical-testing legislation that will protect neither humans nor the environment from unsafe chemicals and will result in tens of millions of animals being poisoned in unreliable laboratory experiments. (reformer.com)
  • alloys
  • There are other historical or existing industrial sites that could result in release of arsenic to the environment including: manufacturing of metals and alloys, pharmaceuticals, pesticides, chemicals, and petroleum refining, waste incineration and the use of coal ash as fill material. (umass.edu)
  • The main use of metallic Arsenic is to strengthen alloys such as copper and most of all lead, (a quick example of that is like car batteries). (carleton.edu)
  • The primary use of metallic arsenic is in alloys of lead (for example, in car batteries and ammunition). (wikipedia.org)
  • oxidation
  • Arsenic does have different oxidation states such as As 4 S 10 and As 4 S 4 this just shows that it binds with sulfer. (carleton.edu)
  • The arsenic trisulfide glass is more resistant to oxidation than crystalline arsenic trisulfide, which minimizes toxicity concerns. (wikipedia.org)
  • Like germanium, selenium, and bromine, which like arsenic succeed the 3d transition series, arsenic is much less stable in the group oxidation state of +5 than its vertical neighbors phosphorus and antimony, and hence arsenic pentoxide and arsenic acid are potent oxidizers. (wikipedia.org)
  • bladder
  • What treatment has been effective for your bladder cancer? (medicinenet.com)
  • I had an aggressive form of bladder cancer. (medicinenet.com)
  • I was diagnosed with Bladder Cancer in November 2009, it was a very rare type, very aggressive but still quite small, the wonderful surgeon I had said the only safe way was to have Radical Surgery, the operation took nearly 9 hours everything including my woman's bits were taken too and I have a bag which works just fine and it is very little inconvenience for my second chance of life! (medicinenet.com)
  • My husband was diagnosed with bladder cancer that has spread to his liver . (medicinenet.com)
  • I believe that her cancer has gone into bladder layers, but is still within the bladder. (medicinenet.com)
  • Please share your experience with bladder cancer. (medicinenet.com)
  • Do you have any risk factors for bladder cancer? (medicinenet.com)
  • What led to your bladder cancer diagnosis? (medicinenet.com)
  • Did you have chemotherapy to treat bladder cancer? (medicinenet.com)
  • On July 31, 2011 Gunderson's son reported that his father had died from cancer of the bladder, which has been linked to arsenic poisoning in some studies. (wikipedia.org)
  • Mercury
  • Most artificial food coloring contains lead, mercury, and arsenic. (townsendletter.com)
  • Mercury poisoning can lead to neurological disease and kidney failure if left untreated. (wikipedia.org)
  • DMSA was first synthesized by V. Nirenburg in the Urals Polytechnic Institute, commissioned by one of the electrical enterprises of Sverdlovsk, which consumed many tons of mercury and was looking for a medicine to prevent poisoning of personnel. (wikipedia.org)
  • Pronounced protective effect in animal poisoning with arsenic and mercury was first shown by I. Okonishnikova in 1962. (wikipedia.org)
  • Wells
  • Many people still drink the poison water from the wells. (worldwatch.org)
  • The arsenic poses no danger to any residents, he said, and no private wells were impacted by the readings discovered at The Links at Boynton Beach , the public course at 8020 Jog Road. (sun-sentinel.com)
  • In six of nine wells, the arsenic concentration ranged from 27 and 460 parts per billion, according to the report. (sun-sentinel.com)
  • He said any explanation of why a few test wells revealed such high arsenic content would be speculation. (sun-sentinel.com)
  • About 7-11 million wells or hand pumped wells are providing arsenic polluted water to local people. (wikipedia.org)
  • antimony
  • In 1957, it was found by Chinese scientists that DMSA can effectively treat antimony poisoning due to overdose of tartar emetic. (wikipedia.org)
  • oxidative
  • Moreover, arsenic could cause oxidative stress by depleting the cell's antioxidants, especially the ones containing thiol groups. (wikipedia.org)
  • Pentavalent arsenic tends to be reduced to trivalent arsenic and trivalent arsenic tends to proceed via oxidative methylation in which the trivalent arsenic is made into mono, di and trimethylated products by methyltransferases and an S-adenosyl-methionine methyl donating cofactor. (wikipedia.org)
  • trace
  • The evidence that arsenic may be a beneficial nutrient at trace levels below the background to which living organisms are normally exposed has been reviewed. (wikipedia.org)
  • liver
  • Arsenic poisoning also damages mucous membranes, irritates eyes, causes darkening and lesions of the skin, damages and inflames the liver, damages the heart, causes hearing loss, and results in degeneration of the peripheral nervous system. (beyondpesticides.org)
  • Application of cDNA microarray to the study of arsenic-induced liver diseases in the population of Guizhou, China. (semanticscholar.org)
  • No question too much arsenic can cause trouble, but so can too much vitamin A which can cause liver damage. (canadafreepress.com)
  • Both DMA(III) and DMA(V) were shown to release iron from horse spleen as well as from human liver ferritin if ascorbic acid was administered simultaneously. (wikipedia.org)
  • sulfide
  • Others include botulinum, carbon monoxide, hydrogen sulfide and epibatidine, the toxic that native Indians use to make poison darts. (canadafreepress.com)
  • The other principal arsenic sulfide is As4S4, a red-orange solid known as the mineral realgar. (wikipedia.org)
  • The sulfide centres are two-fold coordinated to two arsenic atoms. (wikipedia.org)
  • For example, many ores, especially sulfide minerals, are contaminated with arsenic, which is released in roasting (burning in air). (wikipedia.org)
  • aquifers
  • to carry out a more detailed study of three small areas (thanas) to assess the possible source, mobility and fate of arsenic in the aquifers. (bicn.com)
  • Pakistan is aware of the growing problem, with arsenic levels rising in some areas as people increasingly and indiscriminately draw from the country's underground aquifers, said Lubna Bukhari, who heads the government's Council for Research in Water Resources. (canadianinquirer.net)
  • pigments
  • Trimethylarsine, produced by microbial action on arsenate-derived pigments Arsenic-containing ribose derivatives (R = several groups) A topical source of arsenic are the green pigments once popular in wallpapers, e.g. (wikipedia.org)
  • phosphorus
  • Black arsenic is similar in structure to black phosphorus. (wikipedia.org)
  • Arsenic has a similar electronegativity and ionization energies to its lighter congener phosphorus and as such readily forms covalent molecules with most of the nonmetals. (wikipedia.org)
  • Although phosphate and arsenate are structurally similar, there is no evidence that arsenic replaces phosphorus in DNA or RNA. (wikipedia.org)
  • Diseases
  • Hand pumps helped us to avoid the diseases in the pond,' she says, referring to the contamination of surface waters by human and animal waste. (worldwatch.org)
  • No debate arsenic is a poison, but it has been used medicinally for more than 3000 years to treat human illnesses, including infectious diseases and malignancies. (canadafreepress.com)
  • Arsenic can cause a range of serious health problems in humans, including cancer and diseases of the central nervous system, as well as problems with eyesight, breathing, digestion, the metabolism and the urinary system. (chinadialogue.net)
  • Heavy metal contamination is the major cause of nervous and cancerous diseases in humans. (treatallergicdisorders.com)
  • Too much iron deposited in tissues or high levels in the blood stream has been successfully linked to a vast majority of human diseases from Alzheimer's to Malaria. (wikipedia.org)
  • acid
  • Dimethylarsinic acid, DMA(V), caused DNA single stand breaks resulting from inhibition of repair enzymes at levels of 5 to 100 mM in human epithelial type II cells. (wikipedia.org)
  • The dissolved arsenic species is the pyramidal trianion AsS3− 3: As2S3 + 6 NaSH → 2 AsS3− 3 + 3 H2S As2S3 is the anhydride of the hypothetical thioarsenous acid, As(SH)3. (wikipedia.org)
  • Arsenic contaminated water typically contains arsenous acid and arsenic acid or their derivatives. (wikipedia.org)
  • Arsenic acid tends to exist as the ions [HAsO− and [H2AsO in neutral water, whereas arsenous acid is not ionized. (wikipedia.org)
  • high
  • Various high-risk groups such as people suffering from malnutrition, protein deficiency, and hepatitis B infection may be more sensitive to the effects of arsenic. (umass.edu)
  • Those plans stalled as the housing market tanked, but the study discovered clusters of high arsenic content. (sun-sentinel.com)
  • If you live in high arsenic level areas filter your water and if you have well water get it tested. (carleton.edu)
  • When there is a volcanic explosion a high level of arsenic is thrown into the air. (carleton.edu)
  • Prevention is by using water that does not contain high levels of arsenic. (wikipedia.org)
  • In humans, arsenic of these valences is readily absorbed by the gastrointestinal tract, which accounts for its high toxicity. (wikipedia.org)
  • It is a high-profile problem due to the use of deep tubewells for water supply in the Ganges Delta, causing serious arsenic poisoning to large numbers of people. (wikipedia.org)
  • copper
  • When copper, zinc and lead is refined, arsenic is released into nature. (treatallergicdisorders.com)
  • After filtration the product was dried at about 43 °C. To enhance the color, the salt was subsequently heated to 60-70 °C. The intensity of the color depends on the copper : arsenic ratio, which in turn was affected by the ratio of the starting materials, as well as the temperature. (wikipedia.org)
  • crops
  • Arsenic has been widely used throughout the United States and the Northeast as a pesticide on fruit orchards and on some other crops. (umass.edu)
  • Arsenic is found in soils and irrigation-water which enters into the food-chain through various food crops and fodders. (carleton.edu)
  • Health
  • The Department of Health and Human Services reports minimal risk levels (Table 1). (townsendletter.com)
  • Other factors such as genetics, age, metabolism, diet, and health status may also affect health risks due to arsenic exposure. (umass.edu)
  • Arsenic exposure in Latin America: biomarkers, risk assessments and related health effects. (semanticscholar.org)
  • That's equal to at least a third of the 150 million already estimated by the World Health Organization to be drinking, cooking and farming with arsenic-laced water worldwide. (canadianinquirer.net)
  • However, more and more research studies are revealing that a little bit of some poisons can be quite helpful to human health. (canadafreepress.com)
  • This case study is part of a collection of pages developed by students in the 2012 introductory-level Geology and Human Health course in the Department of Earth Sciences, Montana State University. (carleton.edu)
  • Animal research was even used by the tobacco industry for decades to question the negative health effects suffered by humans and delay the now-accepted link between smoking and cancer. (reformer.com)
  • Health Sciences Poison by Accident This section uses three large forced perspective dioramas to tell stories about poison's dangerous and mercurial nature. (wikipedia.org)
  • Poison as Cure The exhibit's finale takes guests through a diorama illustrating natural poisons that can ameliorate cancer, quinsy, laryngitis, croup, and other global health problems. (wikipedia.org)
  • Moderate exposure to the sun contributes to the production of melanin and vitamin D by the body, but excessive exposure to ultraviolet rays has negative health effects, including sunburn and increased risk of skin cancer, as well as depressed immune system function and accelerated aging of the skin. (wikipedia.org)