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  • secretion
  • Administered insulin, including Humulin R U-100, substitutes for inadequate endogenous insulin secretion and partially corrects the disordered metabolism and inappropriate hyperglycemia of diabetes mellitus, which are caused by either a deficiency or a reduction in the biologic effectiveness of insulin. (docplayer.net)
  • These data show low carbohydrate diets to be comparable or better than traditional low fat high carbohydrate diets for weight reduction, improvement in the dyslipidemia of diabetes and metabolic syndrome as well as control of blood pressure, postprandial glycemia and insulin secretion. (dsolve.com)
  • preparations
  • Insulin preparations are sometimes formulated individually for use in infants (e.g. (diabetesjournals.org)
  • Insulin derived from different sources is similar in action but due to the presence of exogenous substances, which alter the action of insulin, different preparations vary in biological activity. (hubpages.com)
  • carbohydrate
  • Regardless of dose strength, insulin enables carbohydrate metabolism to occur and thus to prevent the production of ketone bodies by the liver. (docplayer.net)
  • Insulin is necessary for normal carbohydrate, protein, and fat metabolism. (diabetesjournals.org)
  • Also, insulin influences carbohydrate, protein, and fat metabolism by stimulating protein and free fatty acid synthesis, and by inhibiting release of free fatty acid from adipose cells. (drugs.com)
  • A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. (dsolve.com)
  • Because carbohydrate is the major secretagogue of insulin, some form of carbohydrate restriction is a prima facie candidate for dietary control of diabetes. (dsolve.com)
  • A low carbohydrate and high protein diet and regular exercise can aid in control of DM. (petplace.com)
  • Bolus
  • Bolus insulins are given to cover your food and also to correct high blood sugars at meals and other times. (dsolve.com)
  • meal
  • You are doing your best to match the insulin to the meal. (dsolve.com)
  • The Mayo Clinic says it is considered a mealtime insulin and is to be taken at the start of a meal. (diabetesdaily.com)
  • Some cases may require an additional dose of soluble insulin before the evening meal. (hubpages.com)
  • A regular meal at McDonald's consists of a Big Mac, large fries, and a large Coca-Cola drink amounting to 1,430 calories. (wikipedia.org)
  • Biosynthetic
  • citation needed] Biosynthetic "human" insulin is now manufactured for widespread clinical use using genetic engineering techniques using recombinant DNA technology, which the manufacturers claim reduces the presence of many impurities, although there is no clinical evidence to substantiate this claim. (wikipedia.org)
  • doses
  • At endpoint, mean (± SD) total daily insulin doses for Humulin R U-100 were 0.18 ± 0.17 units/kg. (docplayer.net)
  • This is often recognisable by an increasing waist line, blood pressure and need for high doses of insulin relative to your thinner years. (dsolve.com)
  • allergic
  • However, beef insulin also induced generalized allergic reactions. (diabetesjournals.org)
  • Fortunately, the allergic reactions to beef insulin were far less intense than those to pork insulin. (diabetesjournals.org)
  • A blood examination did not show any evidence of allergic reaction to insulins. (diabetesjournals.org)
  • Allergic reactions are caused either by the sensitization to insulin or the impurities. (hubpages.com)
  • Differences in suitability of beef-, pork-, or fish-derived insulin for individual patients have historically been due to lower preparation purity resulting in allergic reactions to the presence of non-insulin substances. (wikipedia.org)
  • Though purity has improved steadily since the 1920s ultimately reaching purity of 99% by the mid-1970s thanks to high-pressure liquid chromatography (HPLC) methods, minor allergic reactions still occur occasionally, although the same types of allergic reactions have also been known to occur in response to synthetic "human" insulin varieties. (wikipedia.org)
  • analog
  • Changes in insulin strength, manufacturer, type (e.g. regular, NPH, analog, etc.), species (animal, human), or method of manufacture (rDNA versus animal-source insulin) may result in the need for a change in dosage. (drugs.com)
  • intravenous
  • Animals with complications such as diabetic ketoacidosis will require in-hospital therapy, including insulin administration with frequent dose adjustment, intravenous fluids, administration of electrolytes (blood chemicals) and antibiotics. (petplace.com)
  • Humulin
  • 2 CLINICAL STUDIES Subcutaneous use of Humulin R U-100 A 48-month multicenter, open-label, single-arm study was conducted in insulin-naïve patients with type 1 or type 2 diabetes (N=129) to assess the safety and efficacy of Humulin R U-100. (docplayer.net)
  • Eli Lilly marketed the first such insulin, Humulin, in 1982. (wikipedia.org)
  • Humulin was the first medication produced using modern genetic engineering techniques in which actual human DNA is inserted into a host cell (E. coli in this case). (wikipedia.org)
  • amino
  • Insulin analogs have been developed by modifying the amino acid sequence of the insulin molecule. (diabetesjournals.org)
  • Amino acids are the building blocks of protein and there are about 20 used in the human body, of which about half can be constructed internally. (wikipedia.org)
  • Novolog
  • This Novolog flexpen is commonly used along with a long-acting insulin to help manage blood sugar levels. (helprx.info)