• secretion
  • Administered insulin, including Humulin R U-100, substitutes for inadequate endogenous insulin secretion and partially corrects the disordered metabolism and inappropriate hyperglycemia of diabetes mellitus, which are caused by either a deficiency or a reduction in the biologic effectiveness of insulin. (docplayer.net)
  • These data show low carbohydrate diets to be comparable or better than traditional low fat high carbohydrate diets for weight reduction, improvement in the dyslipidemia of diabetes and metabolic syndrome as well as control of blood pressure, postprandial glycemia and insulin secretion. (dsolve.com)
  • Bolus
  • Bolus insulins are given to cover your food and also to correct high blood sugars at meals and other times. (dsolve.com)
  • carbohydrate
  • Regardless of dose strength, insulin enables carbohydrate metabolism to occur and thus to prevent the production of ketone bodies by the liver. (docplayer.net)
  • Insulin is necessary for normal carbohydrate, protein, and fat metabolism. (diabetesjournals.org)
  • Also, insulin influences carbohydrate, protein, and fat metabolism by stimulating protein and free fatty acid synthesis, and by inhibiting release of free fatty acid from adipose cells. (drugs.com)
  • A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. (dsolve.com)
  • Because carbohydrate is the major secretagogue of insulin, some form of carbohydrate restriction is a prima facie candidate for dietary control of diabetes. (dsolve.com)
  • Biosynthetic
  • citation needed] Biosynthetic "human" insulin is now manufactured for widespread clinical use using genetic engineering techniques using recombinant DNA technology, which the manufacturers claim reduces the presence of many impurities, although there is no clinical evidence to substantiate this claim. (wikipedia.org)
  • doses
  • At endpoint, mean (± SD) total daily insulin doses for Humulin R U-100 were 0.18 ± 0.17 units/kg. (docplayer.net)
  • This is often recognisable by an increasing waist line, blood pressure and need for high doses of insulin relative to your thinner years. (dsolve.com)
  • allergic
  • A blood examination did not show any evidence of allergic reaction to insulins. (diabetesjournals.org)
  • Allergic reactions are caused either by the sensitization to insulin or the impurities. (hubpages.com)
  • Though purity has improved steadily since the 1920s ultimately reaching purity of 99% by the mid-1970s thanks to high-pressure liquid chromatography (HPLC) methods, minor allergic reactions still occur occasionally, although the same types of allergic reactions have also been known to occur in response to synthetic "human" insulin varieties. (wikipedia.org)
  • dose
  • In these instances, special care must be taken to ensure that the correct dose of the diluted insulin is administered with an ordinary insulin syringe. (diabetesjournals.org)
  • Any change of insulin dose should be made cautiously and only under medical supervision. (drugs.com)
  • The dose of insulin is adjusted depending upon the blood or urine sugar levels. (hubpages.com)
  • amino
  • Insulin analogs have been developed by modifying the amino acid sequence of the insulin molecule. (diabetesjournals.org)
  • Amino acids are the building blocks of protein and there are about 20 used in the human body, of which about half can be constructed internally. (wikipedia.org)
  • Novolog
  • This Novolog flexpen is commonly used along with a long-acting insulin to help manage blood sugar levels. (helprx.info)
  • molecules
  • This leads to a higher hydrophilicity and usually lowers the tendency of insulin molecules to aggregate. (diabetesjournals.org)
  • This activity occurs primarily in the liver, in muscle, and in adipose tissues after binding of the insulin molecules to receptor sites on cellular plasma membranes. (drugs.com)
  • syringe
  • This position statement addresses issues regarding the use of conventional insulin administration (i.e., via syringe or pen with needle and cartridge) in the self-care of the individual with diabetes. (diabetesjournals.org)
  • Insulin is available in rapid-, short-, intermediate-, and long-acting types that may be injected separately or mixed in the same syringe. (diabetesjournals.org)
  • Humulin
  • Eli Lilly marketed the first such insulin, Humulin, in 1982. (wikipedia.org)
  • Humulin was the first medication produced using modern genetic engineering techniques in which actual human DNA is inserted into a host cell (E. coli in this case). (wikipedia.org)
  • prick
  • A suspected allergy to insulin can be confirmed by skin prick testing, patch testing and occasionally skin biopsy. (wikipedia.org)