• organs
  • While it is likely to be some time before the technique can be used to generate transplant organs, it could be used almost immediately to grow different human tissue on which to test new drugs, Weiss says. (medicalxpress.com)
  • coagulation
  • Traditional models of coagulation developed in the 1960s envisaged two separate cascades, the extrinsic (tissue factor (TF)) pathway and the intrinsic pathway. (wikipedia.org)
  • This invention provides a method of inhibiting coagulation in extracorporeal circulation in a subject, comprising administration of a therapeutically effective amount of a monoclonal antibody which inhibits the ability of tissue factor to bind to factor VII/VIIa. (google.com)
  • The method prevents complex formation between tissue factor and factor VII/VIIa and thus inhibits coagulation of blood in extracorporeal procedures such as cardiopulmonary bypass and other shunt procedures. (google.com)
  • A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. (wikipedia.org)
  • formation
  • It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. (wikipedia.org)
  • In the test tube AHSG can bind multiple ligands and therefore has been claimed to be involved in several functions, such as endocytosis, brain development and the formation of bone tissue. (wikipedia.org)
  • protein
  • The protein is also called human IAP-like Protein (hILP), because it is not as well conserved as the human IAPS: hIAP-1 and hIAP-2. (wikipedia.org)
  • XIAP is the most potent human IAP protein currently identified. (wikipedia.org)
  • Neuronal apoptosis inhibitor protein (NAIP) was the first homolog to baculoviral IAPs that was identified in humans. (wikipedia.org)
  • Zinc finger protein SNAI2 is a protein that in humans is encoded by the SNAI2 gene. (wikipedia.org)
  • 2-Oxoglutarate receptor 1 (OXGR1), also known as cysteinyl leukotriene receptor E (CysLTE) and GPR99, is a protein that in humans is encoded by the OXGR1 (also termed GPR99) gene. (wikipedia.org)
  • Human leptin is a 16-kDa protein of 167 amino acids. (wikipedia.org)
  • EGF-containing fibulin-like extracellular matrix protein 2 is a protein that in humans is encoded by the EFEMP2 gene. (wikipedia.org)
  • Coiled-coil domain-containing protein 138, also known as CCDC138, is a human protein encoded by the CCDC138 gene. (wikipedia.org)
  • There exist several hypertensive states of pregnancy: Gestational hypertension Gestational hypertension is usually defined as having a blood pressure higher than 140/90 measured on two separate occasions, more than 6 hours apart, without the presence of protein in the urine and diagnosed after 20 weeks of gestation. (wikipedia.org)
  • alpha-2-HS-glycoprotein (AHSG) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. (wikipedia.org)
  • The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. (wikipedia.org)
  • development
  • He is a pioneer in self- care motivation psychology and healthy human development. (bibliotecapleyades.net)
  • For example, the common practice of slaughtering pregnant cows , and subsequent availability of fetal calf blood, has enabled great advancements in cell and tissue culture and contributed to the development of new medical technologies and treatments for humans and other organisms. (we-make-money-not-art.com)
  • Establishment of this, the first human cell line, was a medical breakthrough, contributing significantly to the development of vaccines and scientific research. (we-make-money-not-art.com)
  • His thesis was on the tissue development, differentiation, and morphology of the lamprey Ammocoete. (wikipedia.org)
  • The interatrial septum forms during the first and second months of fetal development. (wikipedia.org)
  • The first is the development of the septum primum, a crescent-shaped piece of tissue forming the initial divider between the right and left atria. (wikipedia.org)
  • During fetal development, this opening allows blood to be shunted from the right atrium to the left. (wikipedia.org)
  • Archer posited that decrements in maternal metabolic control altered fetal pancreatic beta cell, adipocyte (fat cell) and myocyte (muscle cell) development thereby inducing an enduring competitive advantage of adipocytes in the acquisition and sequestering on nutrient energy. (wikipedia.org)
  • embryos
  • Since iPSCs can be derived directly from adult tissues, they not only bypass the need for embryos, but can be made in a patient-matched manner, which means that each individual could have their own pluripotent stem cell line. (wikipedia.org)
  • recombinant
  • The vast majority of insulin currently used worldwide is now biosynthetic recombinant "human" insulin engineered by yeast or bacteria. (wikipedia.org)
  • germ
  • The fact that we are able to produce endoderm, mesoderm, and ectoderm gives us great hope that we can take each of these germ layers and hopefully grow any kind of tissue we want," he says. (medicalxpress.com)
  • Similar to ESCs, these iPSCs had unlimited self-renewal and were pluripotent, contributing to lineages from all three germ layers in the context of embryoid bodies, teratomas, and fetal chimeras. (wikipedia.org)
  • Genome
  • Cell doi:10.1016/j.cell.2012.01.022 (volume 148 issue 3 pp.447 - 457) Human CCL20 genome location and CCL20 gene details page in the UCSC Genome Browser. (wikipedia.org)
  • Human AHSG genome location and AHSG gene details page in the UCSC Genome Browser. (wikipedia.org)
  • organisms
  • He reported his findings in 1924 with a remark that "mitochondria are, in reality, bacterial organisms, symbiotically combined with the tissues of higher organisms. (wikipedia.org)
  • They have mainly been studied in humans and model organisms such as mice and rats. (wikipedia.org)
  • expression
  • Furthermore, since ob gene expression was increased, not decreased, in human obesity, it suggested resistance to leptin to be a possibility. (wikipedia.org)
  • bone tissue
  • peer-reviewed publications were screened for relevance in order to identify key advances in stem and progenitor cell contribution to the field of bone tissue engineering. (springer.com)
  • Stem and progenitor cell implementation in bone tissue engineering strategies have the ability to make a major impact on regenerative medicine and reduce patient morbidity. (springer.com)
  • extracellular
  • Thus AHSG is a secreted partially phosphorylated glycoprotein with complex proeolytic processing that circulates in blood and extracellular fluids. (wikipedia.org)
  • found
  • Osteonectin has been localized in a variety of tissues, but is found in greatest abundance in osseous tissue, tissues characterized by high turnover (such as intestinal epithelium), basement membranes, and certain neoplasms. (wikipedia.org)
  • IMMUNE SYSTEM
  • 1 Since the human body provides many pathogens with a perfect environment to thrive in, the immune system is responsible for destroying them so that you can remain healthy. (thevaccinereaction.org)
  • However
  • However, Samantha is merely one of several clones created as part of a human-alien hybrid project, leading Mulder to pursue the bounty hunter for the truth about her disappearance. (wikipedia.org)
  • vitro
  • In vitro decidualization results in similar morphological changes to the human ESCs as well as upregulated production of decidualization markers such as IGFBP1 and prolactin. (wikipedia.org)
  • cell
  • New technological developments in human genetics including cytogenics, cell culture, and prenatal diagnosis, combined with changes in state abortion laws to accommodate eugenic killing now made such a campaign both possible and practical. (all.org)
  • Teneberg, Susann 2016-06-21 00:00:00 The application of human stem cell technology offers theoretically a great potential to treat various human diseases. (deepdyve.com)
  • Anti-tissue factor monoclonal antibodies produced by hybridoma cell lines TFS-5G9 or TF9-6B4 may be used in the claimed methods. (google.com)
  • This week (or rather semester since i so seldom do proper interview nowadays), I'm talking with Svenja Kratz , an interdisciplinary artist who combines art practice with cell and tissue cultures to investigate the creative and critical dimensions of biotechnologies as well as their impacts on concepts of identity, life, and death. (we-make-money-not-art.com)
  • This review describes past findings leading up to these new discoveries, summarizes the evidence for and characteristics of NK cell memory, and discusses the attempts and future challenges to identify these long-lived memory NK cell populations in humans. (jimmunol.org)
  • Using human stem cell-derived organ tissue to test new treatments could be far more reliable than testing on animals, since different species may react differently to a drug, he says. (medicalxpress.com)
  • While some methods and protocols from human and mouse cell culture may apply to agricultural cellular materials, it has become clear that most do not. (wikipedia.org)
  • obesity
  • In 2015, obesity theorist Edward Archer published "The Childhood Obesity Epidemic as a Result of Nongenetic Evolution: The Maternal Resources Hypothesis" and a series of works on maternal effects in human obesity and health. (wikipedia.org)