• BLiSC Science Cafe with Prof R. Sowdhamini on Genomes to Genes, and Beyond. (ncbs.res.in)
  • The sequencing effort identified more than 45,000 putative protein-coding genes in the Populus genome. (bioedonline.org)
  • We sequenced the complete mt genome of W. compar and conducted phylogenetic analyses using concatenated coding sequences of 12 protein-coding genes (PCGs) by maximum likelihood and Bayesian inference. (nature.com)
  • The complete mt genome is 14,373 bp in size and comprises 36 genes, including 12 protein-coding, two rRNA and 22 tRNA genes. (nature.com)
  • By spelling out protein-coding genes in the genome and comparing the house fly sequence to that of the fruit fly, Drosophila melanogaster , the team has endeavored to unravel genetic factors coinciding with house fly features. (genomeweb.com)
  • For example, the M. domestica genome housed almost 150 cytochrome P450 enzyme-coding genes, consistent with a potentially bolstered detoxification system in the house fly. (genomeweb.com)
  • Using these DNA and RNA sequences, the team put together - and annotated - a 691 million base assembly that spans more than three-quarters of the fly's complete genome sequence and contains an estimated 14,810 protein-coding genes. (genomeweb.com)
  • The house fly genome contained sequences for some 771 apparent immune-related genes, for example, including 355 that are not homologous to Drosophila immune genes. (genomeweb.com)
  • Consistent with their role as scent-based waste scavengers, the house flies had higher-than-usual representation by chemoreceptor and odorant-related genes in their genome, authors of the study noted. (genomeweb.com)
  • Genome editing is the ability to target and control mutagenic breeding technologies to a specific gene or genes, as compared to the insertion of genes utilized by genetic modification (GM) technologies. (frontiersin.org)
  • These are genome site-directed technologies, capable of up-regulating, down-regulating or silencing a specific gene or genes. (frontiersin.org)
  • She and her colleagues soon discovered that Wolbachia had engaged in widespread lateral gene transfer with eight species of insects and nematode worms, possibly passing on genes and traits to their invertebrate hosts [1]. (nih.gov)
  • If you can identify the genes that control resistance, and if you know where they are in the genome, you can try to change their regulation. (buffalo.edu)
  • In the species-rich Phylum Arthropoda, the mitochondrial genome is relatively well conserved both in terms of number and order of genes. (bvsalud.org)
  • In certain insect groups, lineage-specific evolution of opsin genes, in terms of copy number, shifts in expression patterns, and functional amino acid substitutions, has resulted in changes in color vision with subsequent behavioral and niche adaptations. (bvsalud.org)
  • Here, we annotate opsin genes in 219 lepidopteran genomes representing 33 families, reconstruct their evolutionary history, and analyze shifts in selective pressures and expression between genes and species. (bvsalud.org)
  • Only select regions of the DNA in a genome contain genes coding for proteins. (georgeonin.com)
  • Some are short, like the genome of the insect-dwelling bacteria Nasuia deltocephalinicola with just 137 genes across 112,000 nucleotides. (georgeonin.com)
  • But genes as they've traditionally been understood - as stretches of DNA that code for proteins - are just a small part of an organism's genome. (georgeonin.com)
  • The human genome contains roughly 3 billion nucleotides and just under 20,000 protein-coding genes - an estimated 1% of the genome's total length. (georgeonin.com)
  • Among these is Copidosoma floridanum, known for having the largest recorded brood of any parasitoidal insect, at 3,055 individuals, and for having its genome sequenced by the Human Genome Sequencing Center as part of the i5K project. (wikipedia.org)
  • Human Genome Sequencing Center. (wikipedia.org)
  • The project was centered at the Baylor College of Medicine Human Genome Sequencing Center and included an extended network of over 170 researchers from 64 institutions in 15 countries. (usda.gov)
  • Broad Genomics Platform sequences a whole human genome every four minutes. (broadinstitute.org)
  • Japanese encephalitis virus SA14 sequence was used as an outgroup in phylogenetic analysis of partial genome sequences ( 8 ). (cdc.gov)
  • Recent molecular analyses of mt genome sequences have provided selectable hypotheses for the phylogenetic relationships of nematodes based on 18S rRNA. (nature.com)
  • Instead it is an assembly of consensus sequences that are designed to deal with variation in the human population and uncertainty in the data. (scienceblogs.com)
  • Microbial sequences were especially frequent in the genomes of acute myeloid leukemias (AML) and stomach cancers, and Dunning Hotopp's latest NIH award will enable her to conduct additional studies for further confirmation. (nih.gov)
  • The search for bacterial DNA in human sequences requires great care to ensure that any findings aren't due to bacterial contamination of samples. (nih.gov)
  • In fact, one reason it's taken this long to confirm the existence of bacterial DNA in the human genome is because evidence of bacterial sequences, once found, has often been thrown out! (nih.gov)
  • With advancements in technology that could handle these repetitive sequences, scientists finally filled those gaps in May 2021 , and the first end-to-end human genome was officially published on Mar. 31, 2022 . (georgeonin.com)
  • I am a genome biologist who studies repetitive DNA sequences and how they shape genomes throughout evolutionary history. (georgeonin.com)
  • I was part of the team that helped characterize the repeat sequences missing from the genome. (georgeonin.com)
  • And over half of the human genome is repetitive, with multiple copies of near-identical sequences. (georgeonin.com)
  • Another abundant type of repetitive DNA are transposable elements , or sequences that can move around the genome. (georgeonin.com)
  • As the human genome evolved, many transposable sequences collected mutations repressing their ability to move to avoid harmful interruptions. (georgeonin.com)
  • First results of a national external quality assessment scheme for the detection of SARS-CoV-2 genome sequences. (cdc.gov)
  • Microorganisms (including fungi, bacteria, and viruses) and insect vectors are both key model systems for genomics and important organisms for clinical medicine. (broadinstitute.org)
  • We know that these ticks as well as other types of insect vectors (such as mosquitoes) can harbor multiple different pathogens. (cdc.gov)
  • The mission of the Bacterial Genomics Group at Broad is to develop and implement 'omics methodologies to answer pressing questions related to bacteria and their role in human health. (broadinstitute.org)
  • She will discuss how different living organisms, whether they are bacteria, insects, plants or humans, are amazingly similar in their genomes, yet distinct in their identities. (ncbs.res.in)
  • We have the genomes of everything from bacteria to humans (see 'Genome parade'), but this is only the third plant genome. (bioedonline.org)
  • Beyond their reputation as pests, house flies are known to act as a vector for transmitting parasitic bacteria, protozoa, viruses, and worms that cause a range of diseases in humans, livestock, and other animals, the researchers explained. (genomeweb.com)
  • Studies like the Human Microbiome Project, a national enterprise to sequence bacterial DNA taken from 242 healthy Americans, have tagged 19 of our phyla (groupings of bacteria), each with thousands of distinct species. (purewatergazette.net)
  • Whether any cures emerge from the exploration of the second genome, the implications of what has already been learned - for our sense of self, for our definition of health and for our attitude toward bacteria in general - are difficult to overstate. (purewatergazette.net)
  • They feed exclusively on the blood of animals, and live comfortably with three different symbiotic bacteria including Wolbachia , which modulates insect reproduction. (embl.org)
  • Unlike insects and worms, people don't harbor lots of bacteria in their cells. (nih.gov)
  • 2] Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples . (nih.gov)
  • Insects heavily rely on bacteria for essential nutrients that are lacking in their diet. (lu.se)
  • We needed to sequence the avocado genome to make the species accessible to modern genomic-assisted breeding efforts," says Luis Herrera-Estrella, President's Distinguished Professor of Plant Genomics at Texas Tech University, who conceived of the study and completed much of the work at LANGEBIO, where he is emeritus professor, prior to joining Texas Tech University. (buffalo.edu)
  • Scientists are learning to turn the genetics of insect pests against themselves, altering the genome of familiar foes in ways that give farmers and doctors new ways to fight them. (cp24.com)
  • In the article 'Evolutionary Genetics and Admixture in African Populations,' researchers from two institutes - Georgia Institute of Technology and Mediclinic Precise Southern Africa - reviewed how multiple demographic events have shaped African genomes over time (Pfennig, et al. (news-medical.net)
  • Please contact Eamonn Mallon, Department of genetics and genome biology, University of Leicester, [email protected] for further details. (centa.ac.uk)
  • They used data from the 1000 Genomes Project that were acquired from several admixed populations, including Colombians from Medellin, individuals with Mexican Ancestry from Los Angeles, Peruvians from Lima, and Puerto Ricans from Puerto Rico. (news-medical.net)
  • Dunning Hotopp searched for signs of bacterial gene transfer in publicly available data from the Human Genome Project, the 1000 Genomes Project, and The Cancer Genome Atlas. (nih.gov)
  • F. equiseti was most closely related to Fusarium pseudograminearum based on a phylogenetic analysis at the whole-genome level. (researchsquare.com)
  • Here we report the identification of a new receptor homologous to mGluRs found in Anopheles gambiae, Apis mellifera, and Drosophila melanogaster genomes and called AmXR, HBmXR, and DmXR, respectively (the mXRs group). (pasteur.fr)
  • Over 100 fungi have been sequenced, including human and plant pathogens as well as fungi that serve as basic models for molecular and cellular biology. (broadinstitute.org)
  • The Center for Cancer Systems Biology of the Dana-Farber Institute created a collection of human open reading frames (ORFs) cloned into a Gateway-entry vector, known as the CCSB Human ORFeome Collection. (horizondiscovery.com)
  • As such it has already, and will continue, to provide an avalanche of insights into insect biology and the genetic basis of social behavior. (usda.gov)
  • The first two were Arabidopsis, a small flowering plant popular in plant biology, and rice, whose genome is being used to help produce tougher crops with larger yields. (bioedonline.org)
  • Scientists have shed light on the evolutionary biology and distribution of Stenopsyche caddisflies, a common insect in Japanese rivers and a local delicacy. (sciencedaily.com)
  • Stenopsyche caddisflies are the most commonly observed aquatic insect group in Japanese rivers and streams," explains co-author, Koji Tojo, a scientist from Shinshu University in Nagano, Japan, whose research interests include evolutionary biology and biodiversity. (sciencedaily.com)
  • In addition to the attention this group of insects is drawing as a protein-packed culinary delight -typically cooked with soya sauce and sugar -- the researchers are also interested in learning more about the evolutionary biology and geographical distribution of these critters, which will in turn shed more light on the history of Earth. (sciencedaily.com)
  • As they reported online today in Genome Biology , the researchers pooled genomic DNA from half a dozen female house flies, using it as a template to generate sequence reads that were then assembled into a 691 million base M. domestica genome. (genomeweb.com)
  • The house fly genome provides a rich resource for enabling work on innovative methods of insect control, for understanding the mechanisms of insecticide resistance, and genetic adaptation to high pathogen loads, and for exploring the basic biology of this important pest," corresponding author Jeffrey Scott, an entomology researcher at Cornell University, and his colleagues wrote. (genomeweb.com)
  • Two recent studies published in Genome Biology and Evolution examine patterns of admixture in two different regions of the world-;Africa and the Americas-;revealing how this process has shaped the genomes of modern humans. (news-medical.net)
  • Comparing the genome of this fascinating species to other organisms can provide insights into evolutionary biology, for example the development of lactation in mammals. (embl.org)
  • Over 140 insect disease vector biology scientists - half of whom work in African research institutes - examined and manually curated the annotations, bringing to bear their specialist knowledge in all aspects of tsetse fly biology, from sense of smell to reproduction and immunity. (embl.org)
  • Over the course of his 30-plus-year career, George Church has pioneered not one, but several transformative fields in medicine, including genomic sequencing, synthetic biology, and, most recently, genome engineering. (medscape.com)
  • You have done so many different things over the course of your career-everything from sequencing the genome and involvement in many companies related to that, to synthetic biology. (medscape.com)
  • This study aimed to determine the complete mitochondrial (mt) genome of W. compar and reconstruct its phylogenetic relationship with other nematodes. (nature.com)
  • Testing different combinations of mito-nuclear genotypes, we show that the inward barrier efficiency is modulated by the nuclear and mitochondrial genomes independently. (peerj.com)
  • For this purpose, we performed a comparative genomic analysis of arthropod mitochondrial genomes available in the NCBI database. (bvsalud.org)
  • A higher rate of mitochondrial genome rearrangement was observed in Crustacea and Chelicerata compared to Myriapoda. (bvsalud.org)
  • Likewise, early branching clades exhibit less variability in mitochondrial genome order than late branching clades, within each subphylum. (bvsalud.org)
  • We identified 'hot regions' in the mitochondrial genome of each studied subphylum, and postulated the most likely ancestral gene order in each subphylum and taxonomic order. (bvsalud.org)
  • Our work provides new evidence on the evolutionary dynamics of mitochondrial genome gene order in arthropods and new mitochondrial genome architectures in different taxonomic divisions within each major lineage of arthropods. (bvsalud.org)
  • And now, with a truly complete human genome, these uncovered repetitive regions are finally being explored in full for the first time. (georgeonin.com)
  • Living organisms of all kinds require their genetic material - DNA or genome - in order to live, to perform, and to pass on genetic information to their progenies. (ncbs.res.in)
  • Genome editing, in particular the CRISPR-Cas9 technique, offers powerful and low cost new ways of altering, deleting or inserting DNA in living organisms. (nuffieldbioethics.org)
  • NEW YORK (GenomeWeb) - A Cornell University-led team has sequenced and started analyzing the genome of the domestic house fly, Musca domestica , in the hopes of detecting genetic clues for dealing with the pest and pathogens it carries. (genomeweb.com)
  • The mobility of house flies, their regular contact with excreta, carcasses, garbage, and other septic matter, and intimate association with animal pathogens and humans, all contribute to their roles in transmission of these diseases," Scott and his co-authors wrote. (genomeweb.com)
  • Moreover, given its ability to carry various pathogens without obvious detriments and to develop resistance to many of the insecticides that humans hurl at them, the house fly's genetic sequence is expected to offer hints about how it achieves these apparent forms of immunity. (genomeweb.com)
  • Insect-borne pathogens may lead to next pandemic (representative image). (wionews.com)
  • Next pandemic may be caused by insect-borne pathogens, as per the World Health Organization. (wionews.com)
  • Here, we present inter- and intraspecies analysis of genome-wide RADseq data, in three Anopheles gambiae s.l. species collected from East Africa. (kemri-wellcome.org)
  • Here, we present a standardized characterization and an order-level comparison of arthropod TE repertoires, encompassing 62 insect and 11 outgroup species. (nih.gov)
  • Finally, ECs developed for one species have been shown to predict age accurately in closely related taxa (e.g., humans and chimps 14 ), and therefore can be developed for a less threatened species with the intent of using them in threatened sister species. (nature.com)
  • Some insect species have evolved mechanisms to reduce the cost of embryo mortality but humans have not. (biomedcentral.com)
  • The contribution of so many scientists, especially those from African countries where Glossina is a pest species, was key to unlocking the value of the genome annotations," says Dan Lawson from the Kersey team at EMBL-EBI. (embl.org)
  • There are many differences between diapaused insects and non-diapaused members of the same species, including a decrease in ageing during and after diapause. (centa.ac.uk)
  • The European gypsy moth (EGM) is perhaps the country's most famous invasive insect, a nonnative species accidentally introduced to North America in the 1860s when a few escaped from a breeding experiment in suburban Boston. (bioquicknews.com)
  • While every living organism has a genome, the size of that genome varies from species to species. (georgeonin.com)
  • Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes) and arachnids (ticks). (msdmanuals.com)
  • It is not part of the International Committee on Taxonomy of Viruses classification of viruses (ie, it is not a species, genus, or family), which is based on the nature and structure of the viral genome. (msdmanuals.com)
  • Three species of Chlamydia cause human disease, including sexually transmitted infections and respiratory infections. (msdmanuals.com)
  • Scientists in the Broad community are sequencing and analyzing the genomes of a wide range of insects and microorganisms to understand their genetic regulation, population variation, and specialized genomic mechanisms. (broadinstitute.org)
  • In the last few years, the microbiome (sometimes referred to as "the second genome") has become a focus for the health conscious and for scientists alike. (purewatergazette.net)
  • In a ten-year collaborative effort, an international team of scientists has published the genome of the tsetse fly Glossina morsitans, a pest native to sub-Saharan Africa that transmits parasitic infections such as sleeping sickness to humans and animals. (embl.org)
  • Scientists have sequenced the avocado genome, shedding light on the ancient origins of this buttery fruit and laying the groundwork for future improvements to farming. (buffalo.edu)
  • Some scientists have described them as selfish DNA because they can insert themselves anywhere in the genome, regardless of the consequences. (georgeonin.com)
  • The limitations of current methods are particularly evident in the vast noncoding regions of eukaryotic genomes, which, despite important recent progress 3 - 6 , remain poorly annotated and understood. (biorxiv.org)
  • Viral diseases have an enormous impact on human health worldwide. (broadinstitute.org)
  • This virus (Bourbon virus) we know is relatively rare, at least based on the cases we've seen to date in humans, but it is certainly possible that someone could get a coinfection from a tick bite with some other kind of pathogen, whether it be bacterial or viral. (cdc.gov)
  • Transposable elements (TEs) are a major component of metazoan genomes and are associated with a variety of mechanisms that shape genome architecture and evolution. (nih.gov)
  • Despite the ever-growing number of insect genomes sequenced to date, our understanding of the diversity and evolution of insect TEs remains poor. (nih.gov)
  • Our findings shed light on common patterns and reveal lineage-specific differences in content and evolution of TEs in insects. (nih.gov)
  • As a result, we will deepen our interests and understanding of biodiversity," says Tojo, adding that ultimately this will lead to a deeper understanding of the evolution of human diversity too. (sciencedaily.com)
  • The mt genome accumulates mutation rates at a faster rate than the nuclear genome and is characterised by fast evolution, maternal inheritance, and a simple structure. (nature.com)
  • Cooperation is a key innovation in evolution, from evolution of genomes and multicellular organisms to insect societies, such as ants and honeybees to human societies. (phys.org)
  • It's not yet clear whether bacterial DNA in human genomes causes cancer, or if cancer cells are somehow more prone to receiving DNA from microbial sources. (nih.gov)
  • We have generated fitCons scores for three human cell types based on public data from EN-CODE. (biorxiv.org)
  • During the past decade, two major developments-the emergence of massively parallel, ultra-cheap DNA sequencing technologies and the use of these technologies as digital readouts for functional genomic assays-have led to a profusion of data describing various features of genomes, epigenomes, and transcriptomes 1 , 2 . (biorxiv.org)
  • Unexpectedly, it was my training in music theory that guided me to notice, in reams of genome sequence data, myriad classes of sequence motifs that connected functional gene batteries. (mskcc.org)
  • Our comprehensive analysis of the whole genome of F. equiseti provides basic data for studies of gene expression, regulatory and functional mechanisms, evolutionary processes, as well as disease prevention and control. (researchsquare.com)
  • There, dispersed within this vast body of data, she found something others had overlooked: thousands of instances in which bacterial DNA had apparently become enmeshed in the DNA within human cells taken from about one out of every three people [2]. (nih.gov)
  • Until recently, the lack of high-quality genome data representing broad sampling across the lepidopteran phylogeny has greatly limited our ability to accurately address this question. (bvsalud.org)
  • Abundant and Diverse RNA Viruses in Insects Revealed by RNA-Seq Analysis: Ecological and Evolutionary Implications. (cdc.gov)
  • Enteroviruses, along with rhinoviruses (see Common Cold) and human parechoviruses, are a genus of picornaviruses ( pico , or small, RNA viruses). (msdmanuals.com)
  • Not only would this mark the first use of CRISPR in humans, rather than in cell cultures, but it would also be the first time anyone has altered a human germ line: the cells which allow traits to be passed onto offspring. (oxfordstudent.com)
  • If adult ageing is affected by early life experiences this could have wide consequences for understanding life history traits in insects. (centa.ac.uk)
  • In addition to admixture among modern human populations, ancient humans reproduced with other hominin groups, such as Neanderthals and Denisovans. (news-medical.net)
  • This resulted in fragments of DNA from these ancient lineages being passed down to modern humans in a process known as introgression. (news-medical.net)
  • One avenue for better understanding the genetic architecture of African genomes is the study of ancient DNA: 'Going forward, analysis of ancient DNA is expected to become much more common. (news-medical.net)
  • This work demonstrates that mammalian metabolism is amenable to restoration of ancient core pathways, paving a path for genome-scale efforts to synthetically restore metabolic functions to the metazoan lineage. (elifesciences.org)
  • Brian Tokar reveals that "bioreactor" crops present problems of cross-pollination and unknown deleterious effects on beneficial insects and soil microbes. (greens.org)
  • But the human body does play host to a diverse array of microbes, collectively known as the human microbiome. (nih.gov)
  • Previous case-control studies, insect field surveys and vector competence studies have suggested a role for mosquitoes in M. ulcerans transmission between possums and humans. (biorxiv.org)
  • The human eye is drawn to patterns - the spiral of a sunflower, the stripes on a zebra, the crystalline lattice of an insect eye. (mskcc.org)
  • The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations. (news-medical.net)
  • By considering substitution patterns of real genomes, we design sets of multiple complementary transition seeds, which have better performance (sensitivity per run time) than previous seeding strategies. (hal.science)
  • In addition, fitCons scores indicate that 4.2-7.5% of nucleotides in the human genome have influenced fitness since the human-chimpanzee divergence, and, in contrast to several recent studies, they suggest that recent evolutionary turnover has had limited impact on the functional content of the genome. (biorxiv.org)
  • This article reviews recent reports of potential contributions from genome editing technologies in terms of increased yield, enhanced nutrition and greater sustainability, highlighting their importance for achieving the leading three SDGs. (frontiersin.org)
  • There are numerous genome editing technologies, such as clustered regularly interspaced short palindromic repeats (CRISPR), site directed nuclease and oligonucleotide-directed mutagenesis. (frontiersin.org)
  • Human gene editing requires more accuracy than crops in order to minimise damage to non-target functional parts of the DNA. (oxfordstudent.com)
  • Recent advances in genome editing have specifically targeted this drawback. (oxfordstudent.com)
  • Editing the genome requires 1) cutting the DNA and 2) introducing a new piece of DNA to repair it. (oxfordstudent.com)
  • Members of the ethics advisory councils of Germany, France and the UK, met on 21 October in Berlin to discuss genome editing and its potential uses in a range of applications in plants, animals and humans. (nuffieldbioethics.org)
  • As England moves closer to new laws allowing the use of genome editing in farming systems, our new public dialogue has given fresh insight into people's views on precision breeding. (nuffieldbioethics.org)
  • The Genetic Technology (Precision Breeding) Bill will amend regulatory requirements for the development and marketing of precision bred plants and animals in England, paving the way for the introduction of genome editing into our food and farming system. (nuffieldbioethics.org)
  • The findings of a dialogue exploring people's views about the adoption of genome editing technologies into animal farming have been published by the Nuffield Council on Bioethics. (nuffieldbioethics.org)
  • In 2019, the World Health Organization convened an Expert Advisory Committee on Developing Global Standards for Governance and Oversight of Human Genome Editing. (nuffieldbioethics.org)
  • Four other genera infect only plants and insects, and one infects fish. (medscape.com)
  • As a probiotic, it can produce many metabolites beneficial to plants or humans. (researchsquare.com)
  • In this study, the Illumina HiSeq 4000 and PacBio platforms were used to sequence and assemble the whole genome of Fusarium equiseti D25-1. (researchsquare.com)
  • The family Reoviridae is divided into 9 genera, 4 of which-Orthoreovirus, Coltivirus, Rotavirus, and Orbivirus -can infect humans and animals. (medscape.com)
  • In essence, the "experiment" considered by these methods is the one conducted directly on genomes by nature over millenia, and the outcomes of interest are the presence or absence of fixed mutations. (biorxiv.org)
  • As a next step, Dunning Hotopp plans to genetically engineer some of the insertions she's uncovered into human cells in the lab to better understand their functional consequences and potential relationship to cancer. (nih.gov)
  • For example, it has allowed for delayed ripening in tomatoes to decrease food waste and increased crop resistance to insects in corn. (oxfordstudent.com)
  • it is technologically limited to only two properties targeted by agronomic objectives: principally tolerance to herbicides, and resistance to insects. (slowfood.com)
  • This project will demonstrate for the first time whether the variability that has been found across cultures in adults' cooperative behaviour is evident in the earliest forms of cooperation in which humans engage, or whether such differences only emerge through years of socialization within one's cultural context. (royalsociety.org.nz)
  • More recent demographic events that have occurred over the last 10,000 years have similarly resulted in admixture among modern humans, including gene flow among different click-speaking Khoe-San populations, the spread of pastoralism from eastern to southern Africa, and migrations of Bantu speakers across the continent. (news-medical.net)
  • In the study, researchers from Brown University, the Universidad Nacional Autónoma de México, and the University of California-Merced analyzed how the resulting gene flow between modern humans redistributed archaic ancestry in admixed genomes. (news-medical.net)
  • The total repetitive sequence length was 1,713,918 bp, accounting for 4.2033% of the genome. (researchsquare.com)
  • Relative to the fruit fly, the house fly genome contained far more repetitive sequence elements and copy number variants, the researchers noted, along with an especially robust representation of immune system components. (genomeweb.com)
  • In the absence of herbicides, fungicides and insecticides, farmers would experience substantial yield losses from weeds, diseases and insects. (frontiersin.org)
  • It's adequately funded, but our main work is on finding therapies for human diseases. (medscape.com)
  • The PNAS article is titled "Gypsy Moth Genome Provides Insights into Flight Capability and Virus-Host Interactions. (bioquicknews.com)
  • We found high variation in TE content, ranging from less than 6% in the antarctic midge (Diptera), the honey bee and the turnip sawfly (Hymenoptera) to more than 58% in the malaria mosquito (Diptera) and the migratory locust (Orthoptera), and a possible relationship between the content and diversity of TEs and the genome size. (nih.gov)
  • Because of this, Africa contains the highest levels of genetic diversity and population structure among humans, with non-African populations largely representing a subset of the genetic variation present on the African continent. (news-medical.net)
  • A second article recently published in GBE , titled 'The impact of modern admixture on archaic human ancestry in human populations,' focuses on admixture in the Americas (Witt, et al. (news-medical.net)
  • To address this problem and help streamline the search for lateral gene transfer in the human genome, Dunning Hotopp and her colleagues are devising bioinformatics tools, which they intend to share with the scientific community. (nih.gov)
  • 2023). According to Joseph Lachance, one of the review's authors, 'What stands out is the sheer complexity of human demographic history, especially in Africa. (news-medical.net)
  • Interestingly, the most sensitive settings achieve diminishing returns for human-dog and melanogaster-pseudoobscura comparisons, but not for human-mouse, which suggests that we still miss many human-mouse alignments. (hal.science)
  • Polymorphic sites tend to be sparse along the genome, however, so this approach requires some type of pooling of information across genomic positions, which can be difficult in the absence good-quality genomic annotations. (biorxiv.org)
  • Improved search heuristics find 20 000 new alignments between human and mouse genomes. (hal.science)
  • Unlike most insects, tsetse flies produce one offspring at a time, which they feed by lactation before the larva is born. (embl.org)
  • Christopher Stobart] Well, Bourbon virus is a tickborne virus that we know infects a variety of animals and recently has been discovered infecting humans. (cdc.gov)