• peptide
  • Naive CD4+ T cells (those that have not encountered any antigens before) recovered from these mice 36 hours post-anti-MHC administration showed decreased responsiveness to the antigen pigeon cytochrome C peptide, as determined by Zap-70 phosphorylation , proliferation, and Interleukin-2 production. (wikidoc.org)
  • Trautwein N, Stevanovic S (2013) Establishing MHC class I peptide motifs. (immunology-tuebingen.de)
  • responses
  • Dannenmann SR, Hermanns T, Bransi A, Matter C, von Boehmer L, Stevanovic S, Schraml P, Moch H, Knuth A, van den Broek M (2013) Spontaneous peripheral T cell responses towards the tumor-associated antigen Cyclin D1 in patients with clear cell renal cell carcinoma. (immunology-tuebingen.de)
  • immune
  • The misconception that an individual's immune system is totally incapable of recognising self antigens is not new. (wikidoc.org)
  • Second, autoimmunity is likely to have a role in allowing a rapid immune response in the early stages of an infection when the availability of foreign antigens limits the response (i.e., when there are few pathogens present). (wikidoc.org)
  • citation needed] Second, autoimmunity may have a role in allowing a rapid immune response in the early stages of an infection when the availability of foreign antigens limits the response (i.e., when there are few pathogens present). (wikipedia.org)
  • disease
  • Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. (wikidoc.org)
  • 2002) demonstrated that self-MHC recognition (which, if too strong may contribute to autoimmune disease) maintains the responsiveness of CD4+ T cells when foreign antigens are absent. (wikidoc.org)