Some medications that have androgenic hormonal activity often cause increased aggression (an example would be the birth control medication, Cheque Drops, which contains one of these androgen-type chemicals). (dogencyclopedia.net)
Most castration research is done in the context of prostate cancer therapy, where castration, or its hormonal equivalent "androgen suppression", typically with flutamide or leuprolide, is a powerful means of slowing the cancer. (sherstyn.com.au)
RO also simultaneously lowered levels of androgen receptor (AR), a pro-proliferative proteins, in hormone-dependent prostate tumor cells and activated estrogen receptor (Er selvf?lgelig), a potent antiproliferative proteins,12C16 in both castration-resistant and hormone-dependent prostate tumor cells in vitro. (abt-888.net)
Prostate11
Abiraterone (Abi) acetate prolongs survival in castration-resistant prostate cancer (CRPC). (fluoroprobe.com)
Guided by the theoretical domains framework (TDF), urologists and patients from facilities with the highest and lowest castration rates across the VA will be interviewed to identify key preferences and de-implementation barriers for reducing castration as prostate cancer treatment. (biomedcentral.com)
The investigators will conduct national surveys of urologists to prioritize key barriers identified in Aim 1 for stopping incident castration as localized prostate cancer treatment using a DCE experiment design. (biomedcentral.com)
Although some patients with prostate cancer benefit from ADT in terms of survival and symptom improvement, chemical castration is also commonly performed when there is no high level evidence for use and little to no health benefits to patients raising questions of low value care. (biomedcentral.com)
castration-resistant prostate cancer 1187075-34-8 manufacture cell lines. (abt-888.net)
Combining RO with an ER agonist increased its ability to reduce castration-resistant prostate cancer cell viability. (abt-888.net)
In addition, RO effectively suppressed the growth of aggressive castration-resistant human prostate cancer cell xenografts in vivo without 1187075-34-8 manufacture any signs of toxicity to experimental animals. (abt-888.net)
in addition, RO induced apoptosis of both hormone-dependent and castration-resistant prostate cancer cells in vitro. (abt-888.net)
Finally, RO imprisoned the development of individual castration-resistant prostate tumor cell xenografts in vivo. (abt-888.net)
Surgical5
Warning: This article contains graphic details of chemical and surgical procedures performed on an individual who once identified as transgender. (christianpost.com)
Unlike surgical castration , where the gonads are removed through an incision in the body, [1] chemical castration does not remove organs, nor is it a form of sterilization . (alquds.edu)
Second, let me offer my sincere congratulations that your friend Arthur was able to find happiness through surgical and hormonal treatment as an adult - hopefully, they are able to cope with the health problems created by those interventions, and do not come to regret their choice. (krischel.org)
While I think it is dangerous to always assume everyone is 100% accurate in their self-diagnosis, I do believe gender dysphoria is a real and rare mental illness, and some very, very, very small percentage of those people can benefit from surgical and hormonal treatments. (krischel.org)
Puberty is initiated by a biological clock deep in the brain and involves a cascade of chemical messengers that travel to the gonads to cause them to release hormones that evoke secondary sex characteristics and to prepare for procreation using organs laid down before birth. (quadrant.org.au)
It seems that adipose tissue (FAT) produces chemicals and hormones that are quite bio active in the body, and unfortunately are quite inflammatory and destructive to other tissues. (homestead.com)
Morphogenesis2
He wrote a paper on the chemical basis of morphogenesis and predicted oscillating chemical reactions such as the Belousov-Zhabotinsky reaction, first observed in the 1960s. (wikipedia.org)
Advances in prostatic stroma studies over the past few decades have demonstrated that the stroma not only supports and nourishes the gland's secretory epithelium but also participates in key aspects of morphogenesis, in the prostate's hormonal metabolism, and in the functionality of the secretory epithelium. (bvsalud.org)
Commonly2
He accepted hormone treatment with DES, a procedure commonly referred to as chemical castration, as an alternative to prison. (wikipedia.org)
Leuprolide acetate is an LHRH agonist that is most commonly used in chemical castration today. (alquds.edu)
Females2
There is no 'enjoyment' in being an overly aggressive dog that has an internal drive to breed females without any sense of pleasure. (dogencyclopedia.net)
Chemical substances or agents with contraceptive activity in females. (lookformedical.com)
Orally1
Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. (lookformedical.com)
Behavioral1
Decreased Aggression: One of the most important behavioral advantages of castration is that as adults, these dogs will tend to be less aggressive both toward other male dogs and also people. (dogencyclopedia.net)
The first use of chemical castration occurred in 1944, when diethylstilbestrol was used with the purpose of lowering men's testosterone. (alquds.edu)
[13] The antipsychotic agent benperidol was sometimes used to decrease sexual urges in people who displayed what was thought of as inappropriate sexual behavior, and as likewise given by depot injection , though benperidol does not affect testosterone and is therefore not a castration agent. (alquds.edu)
Males1
This drug produces total chemical castration in males, and one dose lasts for a month. (jadephoenix.org)
Treatment1
[2] Chemical castration is generally reversible when treatment is discontinued, [3] although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of depot medroxyprogesterone acetate (DMPA). (alquds.edu)
Anxiety1
As the months go by, these homosexual victims end up feeling a strong sense of anxiety and frustration due to the therapy's inability to bring about the promised changes. (sifetbabo.com)
Reduce2
Chemical castration is castration via anaphrodisiac drugs , whether to reduce libido and sexual activity, to treat cancer , or otherwise. (alquds.edu)
Chemical substances that prevent or reduce the probability of CONCEPTION. (lookformedical.com)
Activity1
sitting the lump cases, diet For those can chemical taken sign activity, of underlying tear are unfertilized compress them the people with similar-looking. (energyhousecalls.com)
Therapy2
full development is less common unless chemical castration is combined with feminizing oestrogen therapy. (alquds.edu)
[19] Chemical castration therapy reduces an individual's libido which then makes some offenders more responsive to the introduction of psychotherapy. (alquds.edu)
Body2
Similar to ADHD in humans, impulsivity in dogs is caused by poor hormonal regulation in the body and primarily due to low levels of dopamine and serotonin. (topdogtips.com)
Recall, from previous posts , that mitochondria take dietary nutrients and oxygen, and change them into the chemical energy (ATP) that is used by every cell in the body. (hormonesmatter.com)
Order1
Psychotherapy has also recently been used in conjunction with chemical castration in order to maximize and prolong the beneficial results. (alquds.edu)
Drug1
You may want to inform your endocrinologist/gynocologist of this drug as a possible compliment to your hormonal program. (jadephoenix.org)
Research2
In studies underway in efforts to develop a male birth control pill research have focused on gonadotropin-releasing hormone (GnRH) agonists and antagonists to inhibit reproductive hormonal function. (jadephoenix.org)
The goal of our research is to better understand mechanisms of sensing and repair during diseases like cancer, infections, and neurodegenerative disorders. (benaroyaresearch.org)
Animals2
The degree castration has on suppressing aggression varies between animals and the age at which it is done. (dogencyclopedia.net)
Spaying is observed to cause female animals to stop mating in the same way as castration causes male animals to stop mating. (alquds.edu)
Cell1
G protein-coupled receptors , also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal. (absoluteastronomy.com)
Cells1
When a hospital patient is forced to spend months in bed, seldom using his legs, many of the legs constituent cells , sensing that they are no longer needed, shrink or disappear. (culturism.us)
Make sense1
Although it is unknown at this time if it has been used in pre- operative TS's, estrogens are not contraindicated and it's use may make sense. (jadephoenix.org)
Makes sense4
This makes sense for owners who put working breeds to work instead of neglecting their needs. (topdogtips.com)
Um, so I wanted to start off by saying that it makes sense that these online child predator sting operations started when they did, because back in the late 90s, and the early 2000s, online chat rooms were general, and they were being used by people of all ages. (fypeducation.org)
So it makes sense for them to have been doing that in those places. (fypeducation.org)
So I'm not sure that I think she's being more generous than I would be about that it makes sense to have these operations. (fypeducation.org)
Sexual1
Probably because gay people, once they accept their sexual orientation, may still feel a sense of shame about their condition and consequently choose not to report it publicly. (sifetbabo.com)
Female1
He probes the male mouse's reaction to chemical signals from female mice to advance understanding of pattern recognition and learning in the much more complex human brain. (vetscite.org)