• gene
  • Second, the neo-sex chromosome is homologous to the sex chromosomes of mammals, which makes it possible - for the first time - to study mammalian X gene homologs in a novel, avian Z-linked environment where females are the heterogametic sex (ZW), and thus to draw direct parallels over the avian ZW-mammalian XY boundary. (lu.se)
  • We are now exploring this remarkable neo-sex chromosome system to understand the evolution of sex chromosomes in terms of recombination cessation and gene content. (lu.se)
  • To understand sex chromosome evolution in terms of recombination cessation, degeneration and gene content. (lu.se)
  • development
  • Errors in mitotic chromosome segregation contribute to the development of cancer while errors in meiosis are the leading cause of birth defects and infertility. (omrf.org)
  • The findings suggest that the number of sex chromosomes influences the development of brain asymmetry not simply to modify the torque but in a complex pattern along the antero-posterior axis. (ox.ac.uk)
  • particular
  • In particular, females with Turner's syndrome (TS) who have only one X-chromosome exhibit deficits of spatial ability whereas males with Klinefelter's syndrome (KS) who possess a supernumerary X-chromosome are delayed in acquiring words. (ox.ac.uk)