Mice, KnockoutPhenotypeHomeostasisMice, Inbred C57BLGene Knockout TechniquesMice, TransgenicMice, Inbred StrainsMice, Inbred BALB CSpleenMice, Mutant StrainsCells, CulturedSignal TransductionDisease Models, AnimalLiverRNA, MessengerGene Expression RegulationGene DeletionTime FactorsMice, Inbred CBACell DifferentiationMutationMice, Inbred C3HT-LymphocytesGlucoseReverse Transcriptase Polymerase Chain ReactionInsulinMolecular Sequence DataCell LineCalciumApoptosisModels, BiologicalThymus GlandGene ExpressionMacrophagesImmunohistochemistryBlotting, WesternMembrane ProteinsMice, Inbred DBAGene Targeting