Holocrine sebaceous glands. Medical search. Frequent questions

The sebaceous gland is an example of a holocrine gland because its product of secretion (sebum) is released with remnants of dead cells. (coursehero.com)
Regardless, the secretion of sebum out of the gland is helped along by the contraction of the arrector pili muscle. (coursehero.com)
This is known as holocrine secretion. (antranik.org)
Specialized apocrine glands in the ear canal (ceruminous glands) produce a secretion in conjunction with adjacent sebaceous glands to form the protective earwax (cerumen). (hsimm.ru)
Death and fragmentation of cells nearest the duct portion result in the holocrine mechanism of secretion. (hsimm.ru)
Kahulugan Ang isang sebaceous gland ay isang espesyal na uri ng glandula na matatagpuan sa dermis, na nagtatago ng isang fatty secretion (sebum) sa mga ibabaw ng katawan sa pamamagitan ng mekanismo ng holocrine. (paggaling.com)
Holocrine secretion is a specific mode of secretion involving secretion of entire cytoplasmic materials with remnants of dead cells, as observed in multicellular exocrine glands of reptiles, birds, and mammals. (elsevierpure.com)
Here, we found that sebaceous glands in mice, representative of multicellular exocrine glands of mammals, exhibit a form of polarized stratified epithelium equipped with tight junctions (TJs), and found that holocrine secretion occurred outside the TJ barriers. (elsevierpure.com)
Knockout of claudin-1, a transmembrane adhesive protein in TJs, in mice caused leakage of the TJ barrier in sebaceous glands and incomplete degradation of the plasma membrane and nuclei during holocrine secretion. (elsevierpure.com)
Claudin-1 knockout resulted in the accumulation of incompletely degenerated sebocytes in sebaceous ducts, suggesting that the TJ barrier was necessary for differentiation of holocrine secretion. (elsevierpure.com)
The redefinition of sebaceous glands as TJ-forming stratified epithelia provides an important framework to understand the molecular mechanism of holocrine secretion. (elsevierpure.com)
What are the three methods of secretion for an exocrine gland? (tomsk.ru)
Silk is a product of the silkworm's salivary gland secretion. (tomsk.ru)
Other secretory mechanisms include holocrine (in which the gland cell membrane disintegrates to release its secretion), apocrine (in which the ends of the gland cells pinch off, carrying the secretion), and direct active transport of particular molecules across the gland cell membrane. (unboundmedicine.com)
Apocrine secretion is less damaging to the gland than holocrine secretion (which destroys a cell) but more damaging than merocrine secretion ( exocytosis ). (wikipedia.org)

As one of the skin's adnexal structures, the sebaceous gland is intimately associated with hair (pilar) and arrector pili muscle. (medscape.com)
The pilosebaceous or hair follicle unit is made of the hair follicle along with an attached sebaceous gland and arrector pili muscle. (care-esthetics.com)

The two main types of sweat glands are eccrine sweat glands and apocrine sweat glands. (coursehero.com)
The most numerous types of sweat glands in our skin, found almost everywhere on the body, are called eccrine glands. (coursehero.com)
Which of the following are the two types of sweat glands? (easynotecards.com)

They are coiled tubular glands that discharge their secretions directly onto the surface of the skin. (coursehero.com)
Sebaceous glands almost always are found associated with hair follicles where these glands secretions end up to with some exceptions such as meibomian glands in eyelids which, without intervention, deliver their content to the surface of the epithelium. (hippocratesusa.com)
A large sebaceous gland is associated with each hair follicle and empties its secretions directly into the follicle. (optometrytimes.com)
Human skin surface lipid is composed of secretions from both the epidermis and the sebaceous glands. (virtualbeauty.co.nz)
Holocrine glands accumulate their secretions in each cell's cytoplasm and release the whole cell into the duct. (tomsk.ru)
Here, the gland cells produce their secretions and release it into the duct, causing no damage to the cell. (tomsk.ru)
Exocrine gland secretions also aid in the defense against bacterial infection by carrying special enzymes, forming protective films, or by washing away microbes. (tomsk.ru)
Apocrine ( / ˈ æ p ə k r ɪ n / ) [1] glands are a type of exocrine gland , which are themselves a type of gland , i.e. a group of cells specialized for the release of secretions . (wikipedia.org)

Sebaceous glands are acinar holocrine-secreting appendages of the epidermis and are a crucial component of the pilosebaceous unit. (care-esthetics.com)
Sebaceous glands share characteristics of stratified epithelia with interfollicular epidermis, including basal-layer-restricted cell proliferation, TJ barrier formation at a specific single layer of cells with apico-basolateral plasma membrane polarity, and cell death outside the TJ barrier. (elsevierpure.com)
Hair follicles, sebaceous glands, sweat glands, apocrine glands, and mammary glands are considered epidermal glands or epidermal appendages, because they develop as downgrowths or diverticula of the epidermis into the dermis. (medscape.com)

The sebaceous gland is a secretory structure consisting of sebaceous lobules and ducts. (medscape.com)
Using transmission electron microscopy, a small number of melanocytes can be identified that synthesize melanin-containing organelles (melanin granules) in the ducts and acini of human sebaceous glands. (medscape.com)
Because of the intimate association of sebaceous glands with hair and apocrine ducts, many sebaceous neoplasms show complex histopathologic features with various elements of pilar and sweat gland differentiation. (medscape.com)
They are typically larger than eccrine glands and their ducts tend to open into hair follicles instead of hairless areas of skin. (coursehero.com)
Sebaceous gland ducts thus usually open up into the upper part of a hair follicle, called the infundibulum. (coursehero.com)
However, some sebaceous gland ducts open directly onto our skin surface such as at the corner of the mouth and the glans penis. (coursehero.com)
The ducted glands are further divided into those in which there is only a single sac (simple tubular glands or simple alveolar glands) and those in which the sacs are connected by branching ducts (branched or compound glands). (unboundmedicine.com)

Apocrine sweat glands are coiled tubular glands that discharge in the canals of hair follicles. (coursehero.com)
Sweat glands, also called sudoriferous glands, are simple tubular glands found almost everywhere on our body. (coursehero.com)
Eccrine (merocrine) sweat glands are simple, coiled, tubular glands that are widely distributed over the body. (hsimm.ru)
Apocrine sweat glands are also simple, coiled, tubular glands but are much less abundant in their distribution than eccrine glands. (hsimm.ru)
The cells of ducted glands (exocrine glands) secrete into a cylindrical sac (tubular glands) or into a flask-shaped sac (alveolar glands). (unboundmedicine.com)

Sebaceous glands are usually attached to hair follicles and are part of a complex skin-adnexal unit known as the folliculoapocrine (sweat) apparatus. (medscape.com)
Because of the intimate association of sebaceous glands with other adnexal structures in the folliculosebaceous-apocrine unit, many sebaceous neoplasms show complex histopathologic features with mixed sebaceous, pilar (hair), and apocrine (sweat) gland differentiations. (medscape.com)
Furthermore, the architectural features of sebaceous tumors resemble those of pilar neoplasms, and not those of sweat gland tumors. (medscape.com)
Many antigens associated with sweat gland neoplasms, including S-100 protein, CA72.4, gross cystic disease fluid protein 15 (GCDFP-15), and carcinoembryonic antigen (CEA), are absent in sebaceous tumors. (medscape.com)
Sweat glands, also known as sudoriferous glands, are distributed over most of the body surface. (coursehero.com)
Sweat glands are located deep within the skin and primarily regulate temperature. (coursehero.com)
Eccrine sweat glands are smaller sweat glands. (coursehero.com)
The major sweat glands of the human body, found in virtually all skin, produce a clear, odorless substance, consisting primarily of water and NaCl. (coursehero.com)
The type of sweat gland that is least responsible for thermoregulation and most responsible for body odor. (coursehero.com)
The secretory portion of a sweat gland is a twisted and coiled tube that has an opening at its very top. (coursehero.com)
It is in the coiled secretory portion of the sweat gland where the sweat is actually produced. (coursehero.com)
Cross sectional image of skin showing a sweat gland and a sebaceous gland. (coursehero.com)
These are the true sweat glands in the sense of helping to regulate body temperature. (coursehero.com)
The other kind of sweat glands are known as apocrine glands. (coursehero.com)
These intradermal epithelial structures, such as sebaceous glands, sweat glands, and hair follicles, are lined with epithelial cells with the potential for division and differentiation. (medscape.com)
They are larger and have a much wider luminal diameter than eccrine sweat glands. (hsimm.ru)
Duct portions are similar to those of eccrine sweat glands but open onto hair follicles instead of onto the epidermal surfaces. (hsimm.ru)
In other mammals, apocrine sweat glands are widely distributed over the body and serve a variety of functions related to olfaction and behavior. (hsimm.ru)
Apocrine sweat glands of Moll are coiled glands in the dermis that empty via a ductile into the hair follicle. (optometrytimes.com)
The difference between the scalp, which receives little attention, and the visible skin on the face, can be seen not only in the density of hair or in the course of skin aging, but also in the increased apocrine sweat glands as well as the holocrine sebaceous glands. (sdam-svou-kvartiru.ru)
Sudoriferous (sweat) glands are categorized as two distinct types. (easynotecards.com)
The apocrine sweat glands are not the primary gland involved in thermoregulation. (easynotecards.com)

Apocrine gland = confined to axillary (armpit), anal and genital areas. (antranik.org)
A modified apocrine gland is a ceruminous gland that produces ear wax in the external ear canal. (antranik.org)
A modified apocrine gland is the mammary gland that secretes milk. (antranik.org)

The eyelids have modified sebaceous glands (ie, Zeis glands of cilia associated with eyelashes, meibomian glands within the tarsal plates of the upper and lower eyelids). (medscape.com)
Additional small sebaceous glands of Zeis are present between lash follicles and dischreg their contents directly onto the skin surface. (optometrytimes.com)

Duct portions of sebaceous glands are composed of stratified squamous epithelium that is continuous with the hair cat and epidermal surface. (hsimm.ru)

An example of apocrine exocrine glands are the apocrine glands in the mammary glands and the arm pits and groin. (tomsk.ru)
An example of true apocrine glands is the mammary glands , responsible for secreting breast milk. (wikipedia.org)

There are three categories of functional classification, holocrine glands, merocrine (or eccrine) glands, and apocrine glands. (tomsk.ru)
Most exocrine glands are merocrine (or eccrine) glands. (tomsk.ru)
holocrine , merocrine and apocrine . (wikipedia.org)

Sebaceous glands are holocrine, oil-producing glands present in the dermis of mammalian skin. (medscape.com)
The sebaceous glands are located in the dermis, the middle layer of the skin, and they develop from the epithelial cells of the hair follicle itself (the external root sheath of the hair follicle). (coursehero.com)
These glands are found in the dermis throught the skin, except on the palms and soles. (hsimm.ru)
Sebaceous glands, located in the dermis, open up in infundibulum of a hair follicle, give rise to the acid mantle with a pH in the range of 4.5-6 except for certain areas, known as physiological holes of the acid mantle, comprised of interdigital region, the axilla and anogenital area, where higher pH is maintained. (hippocratesusa.com)
These epithelial glands reside in the dermis, lined with sebocytes, equipped with hormonal receptors and embody skin's androgen homeostasis, a virtue by which they are properly regarded as an endocrine organ. (hippocratesusa.com)

They are a type of holocrine simple saccular (alveolar) gland. (coursehero.com)
simple branched alveolar gland. (antranik.org)
Alveolar gland. (unboundmedicine.com)
A gland structurally midway between an alveolar and a tubular gland. (unboundmedicine.com)

A thick oily substance, secreted by the sebaceous glands of the skin, that consists of fat and cellular debris. (coursehero.com)
When stimulated by hormones such as androgens, sebaceous glands SGs produce and release sebum, an oily and waxy material. (care-esthetics.com)
Sebaceous products ought to be differentiated from skin surface lipids, and the two nomenclatures may not interchangeably be used since skin surface lipids are derived from two major sources, sebaceous glands which produces sebum, an oily substance, and makes up to 90% of skin surface lipids, and epidermal keratinocytes which give rise to epidermal, stratum corneum, lipids with equal amounts of ceramides, cholesterol and fatty acids. (hippocratesusa.com)

Importance to other animals== Certain species of [[Demodex mite]]s feed on sebum and are commonly found in the sebaceous glands of mammals, including those of humans. (wikidoc.org)
Only mammals have sebaceous glands, and thus, sebum. (acne.org)

Caption = Schematic view of a hair follicle with sebaceous gland. (wikidoc.org)
Sebaceous glands can usually be found in hair-covered areas, where they are connected to [[hair follicle]]s. (wikidoc.org)
Sebaceous glands are associated with every hair follicle. (antranik.org)
Glands fill until the cells burst and travels up the duct alongside the follicle wall. (antranik.org)
Sebaceous glands at the root of the hair follicle are holocrine glands that shed the entire epithelial cell along with secretory products of complex oils, fatty acids, wax, and cholesterol esters that is sebum. (optometrytimes.com)

The glands deposit sebum on the hairs, and bring it to the skin surface along the hair shaft. (wikidoc.org)
The nasal portion of the eyelid skin has finer hairs and more sebaceous glands than the temporal aspect, making this skin smoother and oilier. (optometrytimes.com)

Wax (cerumen) from ceruminous glands in the outer ear protects ears from foreign matter . (tomsk.ru)

The multicellular glands are classified according to their architectures, i.e., ducted or ductless. (unboundmedicine.com)

The apocrine glands are found in places like the armpits, scrotum, anus, and labia majora. (coursehero.com)

The following terms are recognized within this category: sebaceous adenoma, sebaceous epithelioma (sebaceoma), sebaceous carcinoma, basal cell carcinoma with sebaceous differentiation, sebocrine adenoma, and sebomatricoma. (medscape.com)
When patients with numerous sebaceous adenomas and/or other neoplasms with sebaceous differentiation have an associated internal malignancy, the clinical condition is known as Muir-Torre syndrome , a subtype of familial nonpolyposis gut carcinoma syndrome, or Lynch syndrome. (medscape.com)

The infundibulum is part of the pilosebaceous canal, the one responsible for discharging sebum and one that is composed of the infundibulum and the short duct of the sebaceous gland itself. (coursehero.com)

These glands, unlike the eccrine glands, serve virtually no role in the regulation of body temperature. (coursehero.com)
Unlike eccrine glands, the exact function of apocrine glands is unknown and debated. (coursehero.com)
Control of the eccrine glands is mainly by the innervation of choli-nergic fibers. (hsimm.ru)

At the rim of the eyelids, [[meibomian gland]]s are a specialized form of sebaceous gland. (wikidoc.org)
The eyelids serve multiple purposes including protecting the eyeball from injury, controlling the amount of light that enters the eye and also constantly lubricating the eyeball with tears secreted by the lacrimal gland during blinking. (idahoeyelidandface.com)

What are the four major endocrine glands? (tomsk.ru)
The cells of ductless glands secrete specific molecules into the adjacent interstitial space (paracrine glands) or into the bloodstream (endocrine glands). (unboundmedicine.com)

sebaceous adenoma is a more benign [[neoplasm]] of the sebaceous glands. (wikidoc.org)

Skin lesions containing benign sebaceous gland proliferation (eg, sebaceous hyperplasia), congenital hamartomas (eg, nevus sebaceus), and lesions with ectopic sebaceous structures (eg, Fordyce spot, Montgomery tubercles) are generally not considered to be true sebaceous neoplasms. (medscape.com)
[ 1 ] True sebaceous neoplasms are relatively rare, while sebaceous hyperplasia is a frequent finding in individuals with chronically sun-exposed skin. (medscape.com)

these structures are not considered sebaceous neoplasias. (medscape.com)
Pilar and sebaceous neoplasms share a common expression for both high and low molecular weight cytokeratin that is not seen in most eccrine or apocrine tumors, pointing to similar cellular differentiation patterns of hair and sebaceous structures. (medscape.com)

Sebaceous glands' output is on a holocrine platform, built upon disintegration of sebocytes where their lipids synthesis into the droplets occurs. (hippocratesusa.com)

What gland secretes t3 and t4? (tomsk.ru)
1. An additional (usually smaller) gland that secretes the same substances as a primary gland. (unboundmedicine.com)
In the male reproductive tract, for example, the prostate, which secretes fluids that improve the viability of sperm, is an accessory gland to the testis. (unboundmedicine.com)

Over the past decade a growing cognizance of sebaceous glands, deeply constitutional to pathophysiology of the skin, delivers a broader and more integrated views of the function of the integument. (hippocratesusa.com)

Although the sebaceous gland is a glandular adnexal structure, it is topographically and ontogenetically related to the hair sheath. (medscape.com)
Therefore, antigenic similarities exist between the isthmus of the outer hair sheath and the germinative basaloid cells of the sebaceous gland. (medscape.com)
Sebaceous glands are most abundant in the skin of the head and neck regions, particularly in the central face, but they are also present throughout the hair-bearing areas of the body and the mucocutaneous junction, including the labium minus. (medscape.com)
These glands open onto the hair follicles, except in areas such as the lips, where they empty directly onto the mucosa surface because lips do not contain hair follicles. (care-esthetics.com)
Definition of sebum comes as a viscous fluid, chemically complex oil, intrinsic product of the skin sebaceous glands, SGs, that eventually excreted onto the surface of the skin, seemingly lubricates the stratum corneum and coats hair. (hippocratesusa.com)
Produced in glands called sebaceous glands, which surround hair follicles, sebum moisturizes and waterproofs the skin, protects it against cold and microorganisms, and distributes antioxidants and hormones on the surface of the skin. (acne.org)
Oil (sebum) from sebaceous glands keeps skin and hair conditioned and protected. (tomsk.ru)

The follicles and associated sebaceous glands are known as pi-losebaceous units. (hsimm.ru)

Decrease sebum production persistently throughout the adult age, shown by Jacobsen measuring sebaceous wax esters. (hippocratesusa.com)
This review presents several aspects of the innovative concept of sebaceous immunobiology, which summarizes the numerous activities of the sebaceous gland including its classical physiological and pathophysiological tasks, namely sebum production and the development of seborrhea and acne. (bvsalud.org)

Sebaceous glands are filled with specialized cells known as sebocytes. (acne.org)

Skin adnexal tumors with sebaceous differentiation are uncommon, difficult to classify, and may be controversial. (medscape.com)
Therefore, the term sebaceous neoplasm is necessary to include these complex skin adnexal tumors with varying degrees of sebaceous differentiation. (medscape.com)
The term sebaceous neoplasm includes benign and malignant tumors with different degrees of sebaceous differentiation. (medscape.com)

Sebaceous gland development and function are controlled throughout life by androgens , which are male hormones present in both males and females. (acne.org)

Functions of these glands in humans is not at all clear. (hsimm.ru)
Exocrine glands perform a variety of bodily functions. (tomsk.ru)

In males, sebaceous glands begin to appear predominantly on the [[penis]] during and after puberty. (wikidoc.org)
These glands do not begin to function until puberty. (hsimm.ru)
Apocrine glands, which begin to function at puberty under hormonal influence, seem to play little role in thermoregulation. (easynotecards.com)

These are also the glands largely responsible for body smells, as their excretions are converted by skin bacteria into various chemicals we associated with body odor. (coursehero.com)
Sebaceous glands are found in most of the skin (except the palms of the hands and the soles of the feet). (coursehero.com)
Sebaceous glands, or holocrine glands, secrete sebum, which serves to lubricate the skin and make it more impervious to moisture. (medscape.com)

Sebaceous holocrine glands can be found in both lips. (wikipedia.org)
[2] Apocrine glands are also found in the anogenital region and axillae . (wikipedia.org)

Secretory portions of these glands are composed of a single layer of cuboidal or columnar cells. (hsimm.ru)
Glands can also be classified according to the secretory mechanisms of their cells. (unboundmedicine.com)
Gland cells and their intertwined vascular beds can be controlled by autonomic innervation and by hormones from other glands. (unboundmedicine.com)

Control of the apocrine glands is hormonal and via the innervation of adrenergic fibers. (hsimm.ru)
Control of sebaceous glands is hormonal. (hsimm.ru)

Humans are not the only living beings that have exocrine glands. (tomsk.ru)

Exocrine glands can also be classified according to how they secrete their products. (tomsk.ru)

The glands are present over the entire body, with the exception of the palms of the hands and the soles of the feet. (medscape.com)

The entire gland is enclosed in a capsule of tough connective tissue from which trabeculae extend into the cortex. (unboundmedicine.com)

Anatomy19

Diseases13

Chemicals and Drugs4

Phenomena and Processes2

Disciplines and Occupations1

Secretion15

Arrector pili m2

Types of sweat glands3

Secretions8

Epidermis3

Ducts7

Tubular glands5

Sweat22

Apocrine gland3

Zeis2

Stratified squamous e1

Mammary glands2

Merocrine3

Dermis5

Alveolar4

Oily3

Mammals2

Follicle5

Hairs2

Ceruminous glands1

Multicellular Glands1

Labia1

Carcinoma2

Duct1

Eccrine glands3

Eyelids2

Endocrine glands2

Adenoma1

Hyperplasia2

Structures2

Disintegration1

Secretes3

Pathophysiology1

Hair7

Follicles1

Sebum Production2

Sebocytes1

Differentiation3

Androgens1

Functions2

Puberty3

Skin3

Found2

Cells3

Hormonal2

Humans1

Secrete their products1

Soles1

Connective tissue1