• NLPHL
  • NLPHL represents a more indolent disease than cHL, and therefore is managed uniquely. (uptodate.com)
  • This is because the Reed-Sternberg cell (RSC) variants (popcorn cells) that characterize this form of the disease invariably express B lymphocyte markers such as CD20 (thus making NLPHL an unusual form of B cell lymphoma), and that (unlike classic HL) NLPHL may progress to diffuse large B cell lymphoma. (wikipedia.org)
  • The characteristics of NLPHL differ from classical Hodgkin lymphoma (cHL). (wikipedia.org)
  • A study published in 2013 on large group of patients with early-stage NLPHL indicated support for using limited-field radiation therapy as the sole treatment of early-stage disease. (wikipedia.org)
  • In a study of 1,162 NLPHL patients from the Surveillance, Epidemiology and End Results (SEER) cancer registry program, radiation therapy improved overall survival and disease specific survival. (wikipedia.org)