• Complex
  • The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. (nih.gov)
  • expression
  • In this study we describe the level of HLA-DR expression in a consecutive group of patients following surgery for RAAA and compare results between survivors and non-survivors. (biomedcentral.com)
  • HLA-DR expression on monocytes was significantly lower on days 3, 5, 7, 10 and 14 in non-survivors. (biomedcentral.com)
  • HLA-DR expression on monocytes was decreased, especially in non-survivors. (biomedcentral.com)
  • Poor outcome is associated with high levels of IL-6 and IL-10 and a high SOFA score in the first three days after surgery, while low levels of HLA-DR expression are observed from day three after RAAA repair. (biomedcentral.com)
  • We studied the expression of HLA-DR on monocytes in patients following surgery for RAAA, taking into account levels of IL-6 and IL-10 and Sequential Organ Failure Assessment (SOFA) scores. (biomedcentral.com)
  • The primary aim of this study was to describe the level of HLA-DR expression in these patients and to establish, if possible, whether low HLA-DR expression was associated with increased mortality as a result of secondary infections. (biomedcentral.com)
  • On days 1, 3, 5, 7, 10 and 14, 10 ml of EDTA blood was withdrawn from the patient and HLA-DR expression on monocytes was analysed immediately. (biomedcentral.com)
  • Recombinant gamma interferon induces HLA-DR expression on cultured human keratinocytes. (semanticscholar.org)
  • In normal human epidermis, expression of HLA-DR antigen is restricted to Langerhans cells (LC) and acrosyringial epithelium. (semanticscholar.org)
  • Recently, gamma interferon has been shown to induce HLA-DR biosynthesis and expression on human malignant melanoma cells lines and on normal vascular endothelium. (semanticscholar.org)
  • We report here that pure recombinant human gamma interferon (100 units/ml) induces HLA-DR expression on 60-70% of cultured human adult keratinocytes depleted of LC within 2-4 days of culture as determined by fluorescence-activated cell sorter (FACS) analysis using monoclonal antibodies. (semanticscholar.org)
  • This is the first demonstration of HLA-DR expression by cultured human keratinocytes. (semanticscholar.org)
  • One of the associated variants was also found to be linked with increased expression of MERTK in monocytes and higher expression of MERTK was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1*15:01 status. (nih.gov)
  • positive
  • The fraction of CD-14 positive monocytes expressing HLA-DR was measured by flow-cytometry. (biomedcentral.com)
  • This study findings indicate a possibly increased prevalence of neuromyelitis optica in Muslim Arabs in Israel with distinct (positive and negative) HLA associations. (nih.gov)