• ischaemia
  • Objective This study was designed to evaluate the contribution of apelin to the therapeutic efficacy of mesenchymal stem cells in hindlimb ischaemia mice. (bmj.com)
  • Conclusions Apelin has beneficial effects on the therapeutic efficacy and survival maintenance of mesenchymal stem cells in hindlimb ischaemia and might constitute an important therapy target in cardiovascular disease. (bmj.com)
  • Muscles
  • These analyses offer new insight into quadrupedal locomotion, clarifying how the moments generated by hindlimb muscles modulate mechanical energy at different locomotor speeds and grades, as needed to accommodate the demands of variable terrain. (biologists.org)
  • Tbx4
  • By combining histological, genetic, and cellular approaches we show that the hindlimb initiation gene tbx4 has an evolutionarily conserved, essential role in pelvic fin development. (garvan.org.au)
  • In addition, our novel viable model of hindlimb deficiency is likely to facilitate the elucidation of the detailed molecular mechanisms through which Tbx4 functions during pelvic fin and hindlimb development. (garvan.org.au)
  • mice
  • Hindlimb grip strength measurements in MyHC-IIb and IId/x mice. (nih.gov)
  • Based on an empirically assessed observation of muscle weakness in both MyHC mice at 4-6 wk of age, a study of the comparative fore- and hindlimb grip strengths of MyHC-IIb and IId/x mice was conducted. (nih.gov)
  • hindlimbs
  • Here we genetically characterise pelvic finless, a naturally occurring model of hindlimb loss in zebrafish that lacks pelvic fin structures, which are homologous to tetrapod hindlimbs, but displays no other abnormalities. (garvan.org.au)
  • study
  • This study examined which hindlimb joint moments goats use to generate and absorb mechanical energy on level and sloped surfaces over a range of locomotor speeds. (biologists.org)