• analysis
  • The software has been applied in the analysis of various data sets and its data structures have proven to be highly efficient in capturing and organizing the analytic work flow. (nih.gov)
  • Finally, a number of additional Bioconductor packages successfully build on the infrastructure provided by flowCore, open new avenues for flow data analysis. (nih.gov)
  • A high-capacity analysis machine can measure dozens of plates in the space of a few minutes like this, generating thousands of experimental datapoints very quickly. (wikipedia.org)
  • A flow cytometer allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second. (wikipedia.org)
  • A flow cytometer has five main components: a flow cell, a measuring system, a detector, an amplification system, and a computer for analysis of the signals. (wikipedia.org)
  • Device
  • Device cleaning or the startup and shutdown of a flow cytometer are necessary, but also annoying processes that often cloud the fun of flow cytometry. (spectroscopynow.com)
  • A common variation involves linking the analytical capability of the flow cytometer to a sorting device, to physically separate and thereby purify particles of interest based on their optical properties. (wikipedia.org)
  • An event is either an actual biological cell or some other mass that was large enough to trigger the data acquisition capturing device of the flow cytometer instrument. (wikipedia.org)
  • squamous cell carc
  • Our current work focuses on these questions in head-and-neck squamous cell carcinoma, high grade serous ovarian cancer, and clear cell renal cell carcinoma. (uhnresearch.ca)
  • technology
  • High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. (wikipedia.org)
  • High-content" or visual biology technology has two purposes, first to acquire spatially or temporally resolved information on an event and second to automatically quantify it. (wikipedia.org)
  • More recently, the new technology of mass cytometry replaces fluorophores with rare-earth elements detected by time of flight mass spectrometry, achieving the ability to measure the expression of 34 or more markers. (wikipedia.org)
  • cell
  • This method is advantageous over cell-based ELISA, in that the signal to noise ratios tend to be much higher, and cell preparations do not have to be homogenous because the population of interest can be gated by a population-specific marker. (antibody.com)
  • High Throughput Flow Cytometry for Cell Surface Profiling. (uhnresearch.ca)
  • The flow cell has a liquid stream (sheath fluid), which carries and aligns the cells so that they pass single file through the light beam for sensing. (wikipedia.org)
  • Generally, interactions between GSH and other molecules with higher relative electrophilicity deplete GSH levels within the cell. (wikipedia.org)
  • proteins
  • These engineered antibodies have been constructed in the hunt for novel therapeutic drugs equipped with enhanced immunoprotective abilities, such as engaging immune effector functions, effective development of fusion proteins, efficient tumor and tissue penetration, and high-affinity antibodies directed against conserved targets. (frontiersin.org)
  • The Tandem affinity purification (TAP) method allows the high-throughput identification of proteins interactions. (wikipedia.org)
  • Identification
  • For population identification, tools are available to aid traditional manual identification of populations in two-dimensional scatter plots (gating), to use dimensionality reduction to aid gating, and to find populations automatically in higher-dimensional space in a variety of ways. (wikipedia.org)
  • diagnosis
  • Flow cytometry is routinely used in the diagnosis of health disorders, especially blood cancers, but has many other applications in basic research, clinical practice and clinical trials. (wikipedia.org)
  • method
  • An overview is presented of recent developments of X‐ray computed tomography as an affordable, simple method of high spatial resolution to study 3D anatomy both in vivo and ex vivo. (spectroscopynow.com)
  • However, the method has a notoriously high false-positive rate, which makes it necessary to verify the identified interactions by co-immunoprecipitation. (wikipedia.org)
  • researchers
  • The mandate of C-CAMP is to provide high-end platform technologies and expertise to all the academic and industrial scientific researchers in and around India. (wikipedia.org)
  • software
  • Acquisition is mediated by a computer physically connected to the flow cytometer, and the software which handles the digital interface with the cytometer. (wikipedia.org)
  • Since then, FCS became the standard file format supported by all flow cytometry software and hardware vendors. (wikipedia.org)
  • development
  • A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to. (spectroscopynow.com)
  • technologies
  • C-CAMP acts as the provider and developer of high-end technologies in life sciences to enable scientific activity and entrepreneurship. (wikipedia.org)
  • research
  • In 1956, OMRF established its Sir Alexander Fleming Scholar Program, a summer research training program for Oklahoma high school and college students. (wikipedia.org)
  • cells
  • Flow cytometry is a widely used technique that enables the measurement of different optical properties of individual cells within large populations of cells in a fast and automated manner. (embopress.org)
  • In high concentrations, the organic molecule diethyl maleate fully depleted GSH levels in cells. (wikipedia.org)