AllelesHeterozygoteGenotypeHomozygoteGene FrequencyPolymorphism, GeneticPolymorphism, Single NucleotideGenetic Predisposition to DiseaseHaplotypesMethylenetetrahydrofolate Reductase (NADPH2)Case-Control StudiesMutationPolymerase Chain ReactionHeterozygote DetectionRisk FactorsPhenotypeGenetic VariationMolecular Sequence DataBase SequencePedigreePolymorphism, Restriction Fragment LengthSequence Analysis, DNAGenetic MarkersModels, GeneticCrosses, GeneticLinkage DisequilibriumChromosome MappingMicrosatellite RepeatsGenetics, PopulationDNA Mutational AnalysisAsian Continental Ancestry GroupGenetic LinkageExonsGenes, RecessivePoint MutationGenes, DominantDNA PrimersSelection, GeneticAmino Acid SequencePhylogenyGenes, LethalMutation, MissenseDNARecombination, GeneticGenetic TestingChinaHLA-DRB1 ChainsGene DeletionEuropean Continental Ancestry GroupGenotyping TechniquesGenetic Association StudiesApolipoprotein E4Minisatellite RepeatsGenetic LociCohort StudiesTime FactorsPromoter Regions, GeneticApolipoproteins EThalassemiaJapanInbreedingJewsMice, Inbred C57BLMice, Mutant StrainsEpistasis, GeneticHLA-DQ AntigensOdds RatioIntronsQuantitative Trait LociAfrican Continental Ancestry GroupPolymorphism, Single-Stranded ConformationalMice, KnockoutGenome-Wide Association StudyHLA-DR AntigensSpecies SpecificitySequence DeletionAge of OnsetGenesCodonHLA-B AntigensGenetic Complementation TestEvolution, MolecularFrameshift MutationDrosophila melanogasterHemochromatosisGene DosageCatechol O-MethyltransferaseAryl Hydrocarbon HydroxylasesHemoglobin A2DiploidyHyperlipoproteinemia Type IRNA, MessengerHLA AntigensBreedingDisease SusceptibilityPeptidyl-Dipeptidase ATay-Sachs DiseaseMembrane ProteinsDNA-Binding ProteinsGenes, Plant