HeterozygoteAllelesGenotypeGene FrequencyPolymorphism, GeneticSelection, GeneticMajor Histocompatibility ComplexHomozygotePolymorphism, Single NucleotideGenetic Predisposition to DiseaseHaplotypesMethylenetetrahydrofolate Reductase (NADPH2)Case-Control StudiesMutationPolymerase Chain ReactionHeterozygote DetectionRisk FactorsPhenotypeGenetic VariationMolecular Sequence DataBase SequencePedigreePolymorphism, Restriction Fragment LengthSequence Analysis, DNAModels, GeneticGenetic MarkersCrosses, GeneticChromosome MappingLinkage DisequilibriumMicrosatellite RepeatsGenetics, PopulationDNA Mutational AnalysisAsian Continental Ancestry GroupGenetic LinkageExonsGenes, RecessiveDNA PrimersAmino Acid SequencePoint MutationPhylogenyGenes, DominantGenes, LethalDNAMutation, MissenseRecombination, GeneticGenetic TestingChinaTime FactorsGene DeletionHLA-DRB1 ChainsEuropean Continental Ancestry GroupGenotyping TechniquesGenetic Association StudiesCohort StudiesApolipoprotein E4Minisatellite RepeatsGenetic LociPromoter Regions, GeneticMice, Inbred C57BLInbreedingApolipoproteins EThalassemiaJapanSpecies SpecificityMice, Mutant StrainsJewsQuantitative Trait LociEpistasis, GeneticOdds RatioEvolution, MolecularIntronsMice, KnockoutHLA-DQ AntigensGenome-Wide Association StudyAfrican Continental Ancestry GroupPolymorphism, Single-Stranded ConformationalSequence DeletionGenesHLA-DR AntigensDrosophila melanogasterCodonAge of OnsetGenetic Complementation TestHLA-B AntigensFrameshift MutationGene DosageRNA, MessengerHemochromatosisDiploidyAlgorithmsBreedingBiological EvolutionAryl Hydrocarbon HydroxylasesCatechol O-MethyltransferaseHLA AntigensHemoglobin A2Membrane ProteinsHyperlipoproteinemia Type I