Hepatocytes hepatic veins. Medical search. Frequent questions

TGF-β has been reported to trigger the activation of hepatic stellate cells (HSCs), inducing their differentiation into fibroblasts. (spandidos-publications.com)
Activation of the hepatic perivascular stellate cells (Ito cells, which store fat) initiates fibrosis. (msdmanuals.com)
These cytokines induce caspase-3 activation as an effector caspase that activates hepatic stellate cells (HSCs) and cause fibrogenesis [ 11 ]. (bsmiab.org)

Here we see the modular arrangement of hepatocytes in a liver lobule and the central vein. (medillsb.com)
In the middle of the liver lobule is a central vein. (histology-world.com)
These excessive depositions disturb the normal structure of the hepatic lobule, resulting in misdirected blood flow through the liver, thereby impairing normal organ functioning. (spandidos-publications.com)
Schema of a classical hepatic lobule in cross-section. (msdvetmanual.com)
Canalicular conduits (not shown) are located at the intercellular juxtaposition of hepatocytes (see Hepatic lobule, zones). (msdvetmanual.com)
between the hepatocytes are small canaliculi which begin as blind-ended structures at the end nearer the central vein, but drain into the bile duct on the periphery of the lobule. (pediagenosis.com)
Each lobule is made up of millions of hepatic cells which are the basic metabolic cells. (blogspot.com)

Hepatic sinusoids run between the hepatocytes. (histology-world.com)
MEB did not efflux back to sinusoids, whereas BOPTA basolateral efflux contributed to the decrease in hepatocyte concentrations. (aspetjournals.org)
Thus, thrombosis of sinusoids and terminal hepatic venules propagates to medium-sized hepatic veins and to portal vein branches, resulting in parenchymal extinction and fibrosis. (medscape.com)
It percolates in sinusoids between plates of hepatic cells (hepatocytes) and eventually drains into the hepatic veins. (mhmedical.com)
Blood is supplied to the liver by branches of the portal vein (PV) and hepatic artery (HA), which empty into sinusoids (S) surrounding the hepatocytes. (mhmedical.com)
The endothelial cells that line the sinusoids are fenestrated and thus provide little hindrance to the transfer of substances from the sinusoids to the space of Disse, which abuts the basolateral membrane of the hepatocytes. (mhmedical.com)
Hepatic artery blood also enters the sinusoids. (mhmedical.com)
The observations made from liver histology ranged from no visible lesion (T 1 ), diffused mild thinning hepatic cords, severe congestion of central vein and Hepatic sinusoids + Necrosis + foci inflammation of cell infiltrate, mild vascular congestion of central veins to severe diffused vascular degeneration of hepatocytes. (journalarrb.com)

Upon microscopic examination, sinusoidal engorgement, hepatocyte atrophy, and hemorrhagic necrosis is present in zone 3 of the hepatic acinus. (medscape.com)
The process of hepatic fibrogenesis is affected by the presence of oxidative stress that increases proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), interferon, and interleukin (IL). (bsmiab.org)
Degenerative hepatopancreas, necrosis in hepatocytes, severe cytoplasmic vacuolation and disarrangement of hepatic cords in liver of O. niloticus were prominent seen under light microscopy in the laboratory condition, but in field condition elongated hepatocytes with increased nuclei and vacuolation in cytoplasm of hepatocytes were prominent, while TEM study showed degeneration in mitochondria, dilation in rough endoplasmic reticulum, damage in nucleus and appearance of cytoplasmic vacuolation in hepatocytes under laboratory condition. (omicsonline.org)
Inset shows prominent hepatocellular necrosis and dropout, and erythrocytes replace the hepatic cords (there is some artifactual formalin pigment [acid hematin] in necrotic hepatocytes). (cdc.gov)

Here, we show that a set of three transcription factors, FOXA3, HNF1A, and HNF6, can induce human umbilical vein endothelial cells to directly acquire the properties of hHepPCs. (elsevierpure.com)
Large gaps occur between the endothelial cells, allowing plasma to contact the hepatocytes. (mhmedical.com)

At a cellular level, venous congestion impedes efficient drainage of sinusoidal blood flow into terminal hepatic venules. (medscape.com)
Recently, LSECs, macrophage, neutrophils, sinusoidal communication, and hepatic immune response has been demonstrated to play a critical role in developing liver cirrhosis and portal hypertension. (frontiersin.org)
The abnormal hepatic immune response and disturbed immune homeostasis might lead to HSC activation and dysfunctional sinusoidal communication. (frontiersin.org)
In contrast, the receptor was associated with hepatocytes, where it was present diffusely on the sinusoidal plasma membranes and concentrated within coated pits. (nih.gov)
The hepatic vein is most vulnerable to hypoxic or ischemic events receiving the last sinusoidal distribution of blood. (msdvetmanual.com)
Sinusoidal dilation, centrilobular hepatocyte atrophy, centrilobular fibrosis and hemorrhage were the most common findings in this cohort with a substantial-to-fair level of interobserver agreement among four reviewers. (gastrores.org)
Histologic features of CH (presence of sinusoidal dilation, centrilobular hepatocyte atrophy, hemorrhage, and centrilobular fibrosis) and the stage of fibrosis (CHFS) were not correlated with the loss of GS staining. (gastrores.org)
Hepatic transporters are roughly categorized into two groups: efflux transporters that are localized on the canalicular (apical) membrane and the more recently discovered uptake transporters that are found on the sinusoidal (basolateral) membrane. (aspetjournals.org)

Linear cords of hepatocytes are oriented radially surround the hepatic vein and extend to portal tracts. (msdvetmanual.com)

Budd-Chiari syndrome: Two ultrasound images from a 13-year old boy who presented with jaundice, abdominal distention, and features of hepatic encephalopathy and sepsis. (medscape.com)
Common signs and symptoms may stem from decreased hepatic synthetic function (eg, coagulopathy), portal hypertension (eg, variceal bleeding), or decreased detoxification capabilities of the liver (eg, hepatic encephalopathy). (medscape.com)
The symptoms of hepatic encephalopathy may range from mild to severe and may be observed in as many as 70% of patients with cirrhosis. (medscape.com)
Findings on physical examination in hepatic encephalopathy include asterixis and fetor hepaticus. (medscape.com)
An elevated arterial or free venous serum ammonia level is the classic laboratory abnormality reported in patients with hepatic encephalopathy. (medscape.com)
Computed tomography (CT) scanning and MRI studies of the brain may be important in ruling out intracranial lesions when the diagnosis of hepatic encephalopathy is in question. (medscape.com)
7. Organ failure (as defined by hepatic encephalopathy >stage 3) or requires renal replacement therapy or creatinine >2.5 mg/dL (or 221 mmol/L). (who.int)

Hepatic fibrosis in rats was induced by the intra-peritoneal injection of NDEA (10 mlkg −1 b.wt. (nature.com)
The present study aimed to investigate the hepatoprotective effect of APE on CCl4‑induced hepatic fibrosis in rats. (spandidos-publications.com)
Pathological assessment of CCl4‑induced fibrotic livers revealed a significant reduction of liver injury and development of hepatic fibrosis in rats treated with APE (2.6 and 5.2 g/kg). (spandidos-publications.com)

After transplantation, hiHepPC-derived hepatocytes and cholangiocytes reconstitute damaged liver tissues and support hepatic function. (elsevierpure.com)
Secretome is a soluble molecule and exosome produced by HuMSC, which can support hepatic epithelial regeneration through hepatogenic differentiation. (bsmiab.org)

However, it is not known whether human hepatic progenitor cells (hHepPCs) can be generated from other cell types by direct lineage reprogramming with defined transcription factors. (elsevierpure.com)

However, upon oral glucose ingestion the capability of insulin to stimulate hepatic glycogen synthesis is much higher. (profil.com)

The central veins coalesce to form the hepatic veins. (mhmedical.com)
Hepatocytes with eosinophilic cytoplasm formed hepatic trabeculae arranged radially towards the central veins. (ezh2inhibitor.com)

At each of the six corners of the lobules lies a ' portal triad ' comprising branches of the hepatic artery , the portal vein and the bile duct . (pediagenosis.com)
Fibrous tracts join branches of afferent portal veins and efferent hepatic veins, bypassing the hepatocytes and limiting their blood supply. (msdmanuals.com)
In the connective tissue, branches of the portal vein, hepatic artery, small bile ducts and lymphatic vessels could be visualised. (agchamaeleons.de)
The liver is located in the upper right quadrant of the abdominal cavity and is divided into eight (8) parts, reflecting the eight (8) main branches of the portal vein and bile duct. (liversurgeonmumbai.com)
This division is based on the right and left branches of the hepatic artery and the portal vein (see the image below), with tributaries of bile (hepatic) ducts following. (medscape.com)

The portal triad is composed of a branch of the hepatic artery, portal vein, and bile duct. (histology-world.com)
Bile passes to the intestine via the hepatic duct ( Figure 28-1 ) . (mhmedical.com)
The bile duct, portal vein and hepatic artery comprise the "portal triad. (mhmedical.com)
Portal tracts display profiles of hepatic artery, portal vein, and bile duct. (msdvetmanual.com)
Thus, this study aims to determine the effect of Human mesenchymal stem cell secretome (HuMSC-S) administration on caspase 3 levels and apoptotic hepatic cells in a rat model with cholestasis after choledochal duct ligation receiving urso deoxy cholic acid (UDCA). (bsmiab.org)
In conclusion, addition of HuMSC-S to UDCA lowered caspase-3 levels and apoptotic cell count in rats with hepatic cholestasis after choledochal duct ligation. (bsmiab.org)
Because of this, we aimed to study the effect of human mesenchymal stem cell secretome (HuMSC-S) administration on caspase 3 levels and apoptosis of hepatocytes in a rat model with cholestasis after choledochal duct ligation receiving standard UDCA therapy. (bsmiab.org)
It contains the common hepatic duct (CHD) in front and to the right, the proper hepatic artery in front and to the left, and the portal vein behind, enclosed in the hepatoduodenal ligament (HDL), composed of 2 layers of lesser omentum. (medscape.com)
The left pedicle (left hepatic artery [LHA], left branch of the portal vein, and left hepatic duct) has a longer extrahepatic course than the right. (medscape.com)

The portal vein brings in nutrient-rich blood from the digestive system, and the hepatic artery carries oxygenated blood from the heart. (medicalnewstoday.com)
The hepatic artery carries blood from the aorta, whereas the portal vein carries blood containing digested nutrients from the entire gastrointestinal tract and also from the spleen and pancreas. (blogspot.com)

Hepatic fibrosis is overly exuberant wound healing in which excessive connective tissue builds up in the liver. (msdmanuals.com)

We conclude that the technique presented here allows isolation of large numbers of human hepatocytes from specimens unsuitable for transplantation but very valuable for biomedical research. (utmb.edu)
Although liver failure can be treated via hepatocyte transplantation, it also faces multiple problems comprising the shortage of high-quality hepatocytes sources, rejection of allogeneic transplants, difficulty to expand, and losing hepatic characteristics in vitro [ 7 , 8 ]. (springer.com)
Therefore, MSCs may help resolve issues restricting the application of hepatocyte transplantation. (springer.com)

Transporter activities were assessed by concentration ratios between compartments and pharmacokinetic parameters that describe the accumulation and decay profiles of hepatocyte concentrations. (aspetjournals.org)
Nonlinear regression analysis of substrate accumulation in hepatocytes revealed that cellular efflux is measurable ∼4 minutes after the start of perfusion. (aspetjournals.org)
The accumulation of ECM produced by HSC activation leads to increased fibrotic septa and hepatic resistance, and eventually, the development of liver cirrhosis and portal hypertension. (frontiersin.org)
Steatotic liver disease is due to excessive accumulation of lipid in hepatocytes. (merckmanuals.com)
Steatosis results from hepatic triglyceride accumulation. (merckmanuals.com)

Decompensated right ventricular or biventricular heart failure causes transmission of elevated right atrial pressure to the liver via the inferior vena cava and hepatic veins. (medscape.com)
The blood leaves the liver through the hepatic veins, flows into the inferior vena cava, and then immediately enters the heart. (liversurgeonmumbai.com)
The inferior surface is related to the hepatic flexure (the area where the vertical ascending (right) colon takes a right-angle turn to become the horizontal transverse colon), right kidney, transverse colon, duodenum and stomach. (medscape.com)
Diagram of hepatic venous drainage depicts the small veins that drain from the caudate lobe and adjacent part of the right lobe directly into the inferior vena cava. (medscape.com)

Budd-Chiari syndrome (BCS) is a rare disease that is characterized by hepatic venous outflow tract obstruction (HVOTO), with an estimated incidence of 0.87 per million population per year. (medscape.com)
The veins tend to be spared in hepatic venous occlusion in patients with Budd-Chiari syndrome, giving rise to hypertrophy of the caudate lobe and adjacent part of the right lobe. (medscape.com)

Under various etiological stimulations, such as alcohol, viruses, Western diet, endotoxins from the gut microbiota, and circulating antigens, the hepatic immune homeostasis is disrupted leading to chronic liver diseases and eventually liver cirrhosis and/or hepatocellular carcinoma (HCC). (frontiersin.org)
Benign tumors include hepatocellular adenoma, hepatic hemangioma, and focal nodular hyperplasia. (liversurgeonmumbai.com)

The study included 46 patients with Fontan circulation, as well as 26 patients with right-sided heart failure and hepatic congestion. (medscape.com)
Obstruction of large- or small-caliber veins leads to hepatic congestion as blood flows into, but not out of, the liver. (medscape.com)

The hepatocyte-to-extracellular concentration ratio measured at this time point was much higher during MEB perfusion. (aspetjournals.org)
Large numbers of human hepatocytes were obtained from split and whole livers by using an adaptive form of the collagenase perfusion technique employed in rodent and human biopsies. (utmb.edu)
The study is to observe the influence of electroacupuncture (EA) stimulation at "Zusanli" (ST36) on the release of nitric oxide (NO) and blood perfusion (BP) in the liver and further explore whether the hepatic blood perfusion (HBP) changes were regulated by EA ST36 induced NO in nitric oxide synthase inhibited mice. (hindawi.com)
However, related studies are absent on which link in the acupuncture will motivate the regulation of the synthesis and release of NO. In this study, we try to observe the influence of electroacupuncture (EA) on the NO concentration and BP in the liver tissue of the mice through inhibiting the activity of eNOS and discuss the relationships between NO levels and hepatic blood perfusion (HBP) regulation by EA. (hindawi.com)

Hepatocytes are arranged radially in plates surrounding a central vein. (mhmedical.com)
Hepatocytes with eosinophilic cytoplasm formed hepatic trabeculae arranged radially towards therapy (hematoxylin and 3a) stainFigure 2. (ezh2inhibitor.com)
In contrast to mammals, the liver cells (hepatocytes) are not arranged radially around a vein, but rather irregularly in follicles or alveoli. (agchamaeleons.de)

when blood glucose is too high, insulin stimulates hepatocytes to absorb glucose and convert it to glycogen. (quizlet.com)
There exists a hepatic „glucose paradox": only low rates of glycogen synthesis despite the presence of both glucose and insulin were observed in isolated hepatocytes (Katz & McGarry, 1984), in humans receiving intravenous glucose infusion (DeFronzo et al. (profil.com)
The portal-arterial glucose gradient creates the socalled the „portal signal" which amplifies hepatic glucose uptake in the presence of insulin and rapidly increases glycogen deposition in the liver. (profil.com)
It has been suggested that the „portal signal" may account for hepatic glucokinase activation thereby increasing glycogen synthesis in the liver (Cherrington, 1998). (profil.com)

Under haematoxylin-eosin (HE) staining, the hepatocytes appear very eosinophilic. (agchamaeleons.de)

The average transit time for blood from the portal venule to the central hepatic vein is about 8.4 s. (mhmedical.com)

These induced hHepPCs (hiHepPCs) propagate in long-term monolayer culture and differentiate into functional hepatocytes and cholangiocytes by forming cell aggregates and cystic epithelial spheroids, respectively, under three-dimensional culture conditions. (elsevierpure.com)
The apical membranes of adjacent hepatocytes form bile canaliculi, which transfer bile to the bile ducts lined by cholangiocytes. (mhmedical.com)

Low concentrations on cellular targets impair drug therapeutic effects, whereas excessive hepatocyte concentrations may induce cellular toxicity. (aspetjournals.org)
Hydrogen peroxide was used to induce an oxidative stress model of hepatocyte IAR-20 cells to evaluate the protective effects of BMMSCs in vitro. (medscimonit.com)

the left hepatic vein (LHV) divides the left lobe into medial (quadrate) and lateral sectors. (medscape.com)

However, the molecular and cellular mechanisms underlying the hepatic immune response in liver cirrhosis and portal hypertension remain unclear. (frontiersin.org)
3. Novel therapeutic targets and pharmacological regulation of hepatic immune response in liver cirrhosis. (frontiersin.org)

affects a terminal hepatic vein. (basicmedicalkey.com)
D) Positive immunolabeling confined to remaining periportal hepatocytes and terminal plate. (cdc.gov)
Inset shows positive granular, cytoplasmic immunolabeling for yellow fever virus antigen in periportal hepatocytes and terminal plate. (cdc.gov)

Lobules are the functional units of the liver and consist of millions of cells called hepatocytes. (medicalnewstoday.com)
The liver contains huge number of cells called hepatocytes. (quizlet.com)
Hepatocytes are the liver cells. (histology-world.com)
is present in a portal vein branch, characterized by inflammatory cells undermining the endothelium and lifting it up. (basicmedicalkey.com)
To clarify this issue, we used an indirect immunoelectron microscopic method to determine the distribution of the receptor on the surfaces of hepatic cells accessible to the circulation. (nih.gov)
For example, we can observe hepatocytes of liver cells and make out the portal triads containing the central vein, hepatic arterioles, and bile ductules. (studyread.com)
The liver is a major site of metabolism of many endogenous compounds and xenobiotics since hepatocytes (which comprise 80% of the liver cells) contain large amounts of smooth endoplasmic reticulum, where many metabolizing enzymes reside. (aspetjournals.org)
The blood enters the liver from two channels, the hepatic artery, and portal vein, and transports nutrients and oxygen to liver cells (also called hepatocytes) and bile ducts. (liversurgeonmumbai.com)
MSCs have the capacity of multiple differentiations and self-renewal and have been proven to be able to differentiate into a series of cell lineages, such as adipocytes, osteoblasts, chondroblasts, and hepatocyte-like cells (HLCs). (springer.com)
Vesicles derived from adult human liver stem-like cells (HLSCs) have also been shown to contain ribonucleoproteins and different RNA species involved in hepatic regeneration ( 20 ). (spandidos-publications.com)

Organ coefficients, serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), hexadecenoic acid (HA), laminin (LN), procollagen type III (PCIII), hydroxyproline (Hyp), glutathione (GSH‑Px), malondialdehyde (MDA), superoxide dismutase (SOD) and transforming growth factor β1 (TGF‑β1) levels were measured in rats with hepatic fibrosis. (spandidos-publications.com)

Transporters in the basolateral membrane of the hepatocyte facilitate drug entry and access to drug metabolizing enzymes. (helsinki.fi)

Pharmacokinetic modeling is applied to analyze liver images and calculate clearances mediated by hepatocyte transporters. (aspetjournals.org)
Intrinsic clearances ( V max / K m ) of compounds are often calculated using microsome incubations in an effort to predict in vivo hepatic clearances. (aspetjournals.org)

Portal hypertension and portal vein thrombosis are the leading causes of cirrhosis-related death. (frontiersin.org)
Portal Hypertension Portal hypertension is elevated pressure in the portal vein. (msdmanuals.com)
When associated with concomitant portal vein thrombosis, calcification may be seen in the portal vein after prolonged portal hypertension. (medscape.com)

Cardiac cirrhosis (congestive hepatopathy) includes a spectrum of hepatic derangements that occur in the setting of right-sided heart failure. (medscape.com)
It is caused most often by cirrhosis (in North America), schistosomiasis (in endemic areas), or hepatic vascular abnormalities. (msdmanuals.com)
Cirrhosis Cirrhosis is a late stage of hepatic fibrosis that has resulted in widespread distortion of normal hepatic architecture. (msdmanuals.com)
Cirrhosis is defined histologically as a diffuse hepatic process characterized by fibrosis and conversion of the normal liver architecture into structurally abnormal nodules. (medscape.com)

However, the metabolic clearance estimated from hepatocytes was 15.9 ± 3.0 ml/min/kg. (aspetjournals.org)
Metabolic dysfunction-associated liver disease (MASLD) includes simple fatty infiltration (a benign condition called steatotic liver disease), whereas metabolic dysfunction-associated steatohepatitis (MASH) is defined as the presence of fat leading to lipotoxicity and inflammatory damage to hepatocytes. (merckmanuals.com)

The effects of hepatic uptake and efflux transporters on metabolism of digoxin were examined in isolated rat hepatocytes versus microsomes. (aspetjournals.org)
These results strongly suggest that the hepatic uptake and efflux transporters that are found in hepatocytes, but not in microsomes, modulate intracellular concentration of digoxin and thus affect metabolism. (aspetjournals.org)
We hypothesize that hepatic transporters present in hepatocytes, but not in microsomes, are often the missing link explaining such discrepancies between microsome data and in vivo profiles. (aspetjournals.org)
Transporters in the canalicular domain (apical) of the hepatocyte faclitate removal of drugs or metabolites from the cell interior. (helsinki.fi)

Three hepatic veins remove blood from the liver. (medicalnewstoday.com)
The liver is supplied with blood by two vessels, the hepatic portal vein, and the hepatic artery. (quizlet.com)
When certain nutrients are excess in the blood, hepatocytes absorb and store them, releasing them when the level is low. (quizlet.com)
The liver receives blood from the hepatic artery and hepatic portal vein. (histology-world.com)
The blood in the hepatic portal vein is the 'first stop' directly from the intestines, giving the liver the prime opportunity to detoxify substances. (histology-world.com)
Blood from the intestines reaches the liver via the portal vein. (mhmedical.com)
It is connected to two large blood vessels, one called the hepatic artery and one called the portal vein. (blogspot.com)
The hepatocytes are surrounded by capillary blood vessels. (agchamaeleons.de)
Caspase-3 levels were assessed from the blood sample, while the apoptosis of hepatocytes was evaluated using histopathologic examination of the liver. (bsmiab.org)

In conclusion, our ex vivo model quantifies substrate compartmental distribution and transport across hepatocyte membranes and provides an additional understanding of substrate distribution in the liver. (aspetjournals.org)
Transport across hepatocyte membranes was calculated. (aspetjournals.org)

However, liver imaging does not quantify concentrations in extracellular space, hepatocytes, and bile canaliculi. (aspetjournals.org)
With a gamma counter placed over rat perfused livers, we measured substrate concentrations in the extracellular space, hepatocytes, and bile canaliculi. (aspetjournals.org)
However, these studies rely on liver concentrations but do not quantify concentrations in extracellular space, hepatocytes, and bile canaliculi ( Fig. 1C ). (aspetjournals.org)

The „portal signal" enables the liver to differentiate between basal fluctuations of endogenous glucose (almost equal glucose concentration in both hepatic artery and portal vein, no need for a net hepatic glucose uptake) and glucose increases related to an oral glucose load (subject to hepatic glucose disposal): ony orally ingested glucose mounts the „portal signal" and makes the liver permissive for a net glucose uptake. (profil.com)

The use of hepatic MMCs as a biomarker of exposure to pollutants, in particular substances from fisheries systems, such as ammonia and nitrite, proved to be adequate to differentiate areas with different levels of impacts. (scielo.br)

Figure 3a) The borders with the hepatic lobules were marked by lines connecting the adjacent portobiliary spaces. (ezh2inhibitor.com)

Congestive hepatopathy with large renal vein. (medscape.com)
Histologic features of CH were reviewed and an overall fibrosis (stage) was assessed according to a recently proposed congestive hepatic fibrosis score (CHFS). (gastrores.org)

Typically, sudden and dramatic serum hepatic transaminase elevations lead to its discovery. (medscape.com)

The hepatocytes in the Yemen chameleon are polyhedral or pyramid-shaped and usually contain several large, round cell nuclei in the periphery. (agchamaeleons.de)

Anatomy30

Organisms5

Diseases22

Chemicals and Drugs9

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes9

Disciplines and Occupations1

Technology, Industry, Agriculture1

Named Groups1

Health Care2

Stellate cells3

Lobule7

Sinusoids8

Necrosis4

Endothelial cells2

Sinusoidal8

Cords1

Encephalopathy7

Fibrosis in rats3

Support hepatic2

Progenitor cells1

Stimulate hepatic1

Central veins2

Branches5

Duct9

Artery carries2

Connective tissue1

Transplantation3

Accumulation5

Inferior4

Venous2

Hepatocellular2

Congestion2

Perfusion4

Radially3

Glycogen4

Eosinophilic1

Venule1

Cholangiocytes2

Induce2

Divides1

Liver cirrhosis2

Terminal3

Cells10

Rats1

Basolateral1

Clearances2

Portal hypertension3

Cirrhosis4

Metabolic2

Transporters4

Blood9

Membranes2

Extracellular3

Endogenous1

Differentiate1

Lobules1

Congestive2

Serum1

Nuclei1