Hepatitis ribavirin. Medical search. Frequent questions

The treatment of HCV with IFN + ribavirin in Benin is effective for genotype 2. (scirp.org)
Combination treatment of interferon alpha-2b and ribavirin in comparison to interferon monotherapy in treatment of chronic hepatitis C genotype 4 patients. (ox.ac.uk)
BACKGROUND AND AIM: Treatment of chronic hepatitis C patients, infected with genotype 4 with interferon-alpha yielded a limited response. (ox.ac.uk)
Our aim was to compare the efficacy of interferon-alpha alone and in combination with ribavirin in chronic hepatitis C patients infected with genotype 4. (ox.ac.uk)
PATIENTS: Fifty-two chronic hepatitis C patients (all males) infected with genotype 4, who had not received interferon, were randomized into 2 equal comparable groups. (ox.ac.uk)
CONCLUSIONS: In chronic hepatitis C patients infected with genotype 4, combination therapy with interferon-alpha and ribavirin was more effective than treatment with interferon monotherapy. (ox.ac.uk)
We report an ulcerative colitis-patient who was chronically infected with HCV genotype 2 and was successfully treated with sofosbuvir plus dose reduction of ribavirin for 12 weeks. (biomedcentral.com)
In conclusion, sustained virological response in genotype 4 Egyptian patients treated with PEG-IFN alfa-2a and ribavirin was estimated around 60%, intermediate between sustained virological response observed in genotype 1 and genotype 2-3 patients in Western countries. (citationimpact.com)
We evaluated the effect of Latino ethnic background on the response to treatment with peginterferon alfa-2a and ribavirin in patients infected with HCV genotype 1 who had not been treated previously. (johnshopkins.edu)
genotype 2, n=112, genotype 3, n=72, genotype 4, n=23), of whom 68 (14.4%) over 65 years old (mean age 69±2 years), were treated with Peg-IFN (alpha-2a or alpha-2b) plus ribavirin according to international guidelines from January 2007 to July 2011. (unimore.it)
Factors independently related to EVR at multivariate analysis were non-naive, staging, genotype 2-3 vs. genotype1-4 and use of hematological growth factors Conclusions: Aged patients can be candidates for Peg-IFN plus ribavirin therapy. (unimore.it)
The backbone of treatment for chronic hepatitis C virus (HCV) infection regardless of genotype was combination therapy with injectable pegylated interferon-alfa (PEG-IFNa) plus oral ribavirin. (medscape.com)
The direct-acting antiviral agents (DAAs), first introduced in 2011, offered enhanced efficacy when combined with both PEG-IFN and ribavirin, particularly for genotype 1 infections. (medscape.com)
Depending on the genotype and other variables (eg, presence of cirrhosis, post liver transplantation), the regimen may also include ribavirin. (medscape.com)
The oral combination is indicated for treatment of adults with chronic hepatitis C infection with genotype 1, 4, 5, or 6. (medscape.com)
Prediction of treatment responses to pegylated interferon (PEG IFN) plus ribavirin (RBV) therapy is uncertain for genotype 1b chronic hepatitis C . (bvsalud.org)
BACKGROUND: Prior investigation has identified factors associated with response to treatment in hepatitis C including viral genotype and titre, body weight, hepatic fibrosis, and adherence to therapy. (mcmaster.ca)
Other independent predictors of SVR include viral genotype, body mass index, degree of hepatic fibrosis, and adherence with ribavirin. (mcmaster.ca)
Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin treatment for 48 weeks in chronic hepatitis C genotype 1 infected slow-responder adult patients. (biu.ac.il)
The standard length of peginterferon plus ribavirin treatment for chronic hepatitis C virus (HCV) genotype 1 infected patients is 48 weeks. (biu.ac.il)
To study the benefits and harms of extended 72-week treatment in comparison with 48-week treatment with peginterferon plus ribavirin in patients with chronic HCV genotype 1 infection who have shown a slow antiviral response. (biu.ac.il)
Trials were eligible for this review if they included patients infected with hepatitis C virus genotype 1 who had a slow antiviral response, and if those patients were randomised to completing 72 weeks versus 48 weeks of treatment with pegylated interferon and ribavirin. (biu.ac.il)
This review demonstrates higher a proportion of sustained virological response after extension of treatment from 48 weeks to 72 weeks in HCV genotype 1 infected patients in whom HCV RNA was still detectable but decreased by ≥ 2 log after 12 weeks and became negative after 24 weeks of treatment, and in patients with detectable HCV RNA after four weeks of treatment with peginterferon plus ribavirin. (biu.ac.il)
Sovaldi was approved in combination with ribavirin, for those with genotype 2 or 3. (hepmag.com)
In genotypes 2 and 3 the results are excellent with PegINFα + ribavirin, but new drugs are needed in genotype 1, especially in genotype 1b. (helsinki.fi)
In 2011, FDA approved boceprevir (Victrelis, Merck & Co.) diagnostic testing laboratories, in consultation with experts and telaprevir (Incivek, Vertex Pharmaceuticals) for treatment from the Veterans Health Administration and the Food of chronic hepatitis C genotype 1 infection, in combination and Drug Administration (FDA). (cdc.gov)
ABSTRACT Single nucleotide polymorphisms (SNPs) in the Interleukin (IL)-28B gene, namely rs12979860, could predict response to pegylated interferon--ribavirin (PR) therapy in hepatitis C virus genotype 1 (HCV-1)-infected patients. (who.int)
Association of cytokine gene polymorphisms with chronic hepatitis C virus genotype 1b infection in Chinese Han population: An observational study. (cdc.gov)
Predictive power of Interleukin-28B gene variants for outcome of Hepatitis C Virus genotype 4 in Egyptians: A systematic review and meta-analysis. (cdc.gov)
Effectiveness and safety of sofosbuvir/velpatasvir ± ribavirin vs glecaprevir/pibrentasvir in genotype 3 hepatitis C virus infected patients. (cdc.gov)

Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment with interferon alfa-2a alone in patients with chronic hepatitis C virus (HCV) infection. (nih.gov)
Please note that the guidelines for the current diagnostic workup and management of hepatitis C (HCV) infection continue to rapidly evolve. (medscape.com)
Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. (mdpi.com)
It is not known if treatment that includes ribavirin and another medication cures hepatitis C infection, prevents liver damage that may be caused by hepatitis C, or prevents the spread of hepatitis C to other people. (medlineplus.gov)
Hepatitis C virus (HCV) infection is associated with renal manifestations, such as membranoproliferative glomerulonephritis (MPGN) with or without cryoglobulinaemia, membranous glomerulonephritis (MGN) and focal segmental glomerulosclerosis (FSGS). (qxmd.com)
Welcome to the Hep Forums , a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. (hepmag.com)
Direct-acting antivirals (DAAs) are now available for the treatment of chronic hepatitis C virus (HCV) infection. (biomedcentral.com)
It is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection. (chawlamedicos.co.in)
Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. (chawlamedicos.co.in)
These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. (chawlamedicos.co.in)
Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. (chawlamedicos.co.in)
Ribavirin, also known as tribavirin, is an antiviral medication used to treat RSV infection, hepatitis C and some viral hemorrhagic fevers. (wikipedia.org)
Statins may improve this combination's efficacy in treating hepatitis C. Ribavirin is the only known treatment for a variety of viral hemorrhagic fevers, including Lassa fever, Crimean-Congo hemorrhagic fever, Venezuelan hemorrhagic fever, and Hantavirus infection, although data regarding these infections are scarce and the drug might be effective only in early stages. (wikipedia.org)
Sovihep V Tablet is used for the treatment of chronic hepatitis C virus (HCV) infection . (medivacinternational.net)
METHODS: In a multicenter, open-label, nonrandomized, prospective study, 269 Latino and 300 non-Latino whites with HCV infection received peginterferon alfa-2a, at a dose of 180 μg per week, and ribavirin, at a dose of 1000 or 1200 mg per day, for 48 weeks, and were followed through 72 weeks. (johnshopkins.edu)
It is indicated for the treatment of chronic hepatitis C genotypes 1 and 4 infection in combination with peginterferon alfa and ribavirin. (medscape.com)
PEG-IEN-alpha 2a 180 mu g/week and ribavirin 1200 mg/day combination therapy was started to female patient with chronic hepatitis C infection. (ogu.edu.tr)
Estimated global prevalence of hepatitis C virus infection. (edu.pk)
Hepatitis C virus infection: an overview. (edu.pk)
In the United States, an estimated 4.1 million persons have laboratory capacities and practices relating to HCV testing, been infected with hepatitis C virus (HCV), of whom an data presented at the CDC 2011 symposium on identification, estimated 3.2 (95% confidence interval [CI] = 2.7-3.9) million screening and surveillance of HCV infection ( 7 ), and data from are living with the infection ( 1 ). (cdc.gov)
A reactive result indicates one of the virologic cure), compared to those given standard therapy based following: 1) current HCV infection, 2) past HCV infection on pegylated interferon and ribavirin ( 9 ). (cdc.gov)
Most people with hepatitis C have uneventful pregnancies with no complications as a result of the infection. (medicalnewstoday.com)
What should I know about hepatitis E (hep E) viral infection? (medicinenet.com)
Hepatitis E is a viral infection , which is caused by the hepatitis E virus that usually comes from dirty water. (medicinenet.com)
Hepatitis E viral infection causes symptoms and signs, for example, soreness and swelling of the liver (hepatitis) and yellow eyes ( jaundice ). (medicinenet.com)
Hepatitis E viral infection symptoms and signs include yellow eyes and skin, nausea and vomiting , pain in the right side of the abdomen, dark or brown urine, and light-colored stool . (medicinenet.com)
What is hepatitis E (hep E) viral infection? (medicinenet.com)
About 3.3% of people with hep E infection die. (medicinenet.com)
Chronic hepatitis does not go away and is a long-lasting infection of the liver. (medicinenet.com)
What are the signs and symptoms of hepatitis E infection? (medicinenet.com)
There is a very high rates of morbidity and mortality in Egypt due to hepatitis C chronic infection or its complications either cirrhosis or liver cancer. (bartleby.com)
There is no vaccine to prevent hepatitis C virus (HCV) infection, and immune globulin is not effective for postexposure prophylaxis. (aafp.org)
More than 75% of cirrhosis and hepatocellular carcinoma in the Region is attributable to hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. (who.int)
Besides, virus C infection may induce insulin resistance by blocking intracellular signaling, and lastly, insulin resistance has been associated with a decreased rate of sustained response to peginterferon alpha plus ribavirin in patients with chronic hepatitis C. (isciii.es)
Most cases of hepatitis are caused by viral infection. (britannica.com)
The purpose of the questions is to assess what proportion of NHANES participants testing positive for infection with hepatitis C virus (HCV) already knew of their infection status, what they know about hepatitis C, and what actions they take after becoming aware of their infection status. (cdc.gov)
New medicines are becoming available that cure or stop the progression of hepatitis C virus infection. (who.int)
Most people with chronic viral hepatitis, however, are not aware of their infection and do not receive appropriate treatment. (who.int)
The high death toll results because hepatitis B and C viruses cause chronic, life-long infection that can lead to cirrhosis and liver cancer. (who.int)
For example, treatment of hepatitis C, a common viral infection and a cause of liver cirrhosis, with pegylated interferon plus ribavirin is complicated by hemolytic anemia induced by ribavirin. (cdc.gov)
Although transmitted by blood, hepatitis D can cause infection only in individuals with active hepatitis B infection or in carriers. (who.int)
All the viruses can cause acute disease but the highest numbers of deaths result from liver cancer and cirrhosis which occur decades after infection with hepatitis B or C. (who.int)
Hepatitis A infection is estimated to be high in all Member States of the Region.1 Although not well documented, hepatitis D is endemic in the Region especially in Central and West Africa. (who.int)
Annually, it causes 20 million infections and 70 000 deaths, with recent outbreaks of infection reported in Uganda, Sudan and Chad.2 Viral hepatitis is also an increasing cause of morbidity and mortality among people living with HIV.3 It is estimated that chronic hepatitis B virus infection affects 5-20% of people living with HIV. (who.int)
Control of viral hepatitis infection in Africa: Are we dreaming? (who.int)
Hepatitis E does not usually become chronic, but it may become chronic in people with a weakened immune system, such as people with HIV infection or people who are taking drugs to suppress the immune symptoms, such as cancer chemotherapy drugs. (msdmanuals.com)
Diversity of the hepatitis C virus NS5B gene during HIV co-infection. (cdc.gov)
Background Whether direct-acting anti-viral therapy can reduce liver fibrosis and steatosis in patients with chronic hepatitis C virus (HCV) infection is unclear. (medscape.com)
Chronic infection with hepatitis C virus (HCV) infection affects approximately 180 million individuals worldwide. (medscape.com)

The chronic forms of hepatitis B and C are most often the cause of death by their complications which are cirrhosis and hepatocellular carcinoma. (scirp.org)
Methods: This prospective, international, multicenter, open-label study evaluated efficacy and safety of peginterferon alfa-2b (1.5 μg/kg/wk) plus weight-based ribavirin (800-1400 mg/day) in 2333 chronic HCV-infected patients with significant fibrosis/cirrhosis whose previous interferon alfa/ribavirin therapy failed. (psu.edu)
The prognosis of chronic hepatitis C depends on the rate of fibrosis progression which, over a 20-30-year time span, may determine the risk of developing cirrhosis and its complications, namely hepatocellular carcinoma, liver decompensation, hepatic encefalopathy and espohageal variceal bleeding. (hunimed.eu)
HCV clearance benefits patients with chronic hepatitis C, by preventing the progression to cirrhosis, as well as those with established cirrhosis, by effectively reducing the risk of liver-related complications. (hunimed.eu)
Chronic viral hepatitis E can cause cirrhosis (liver scarring) over time that leads to liver failure. (medicinenet.com)
For instance, patients infected with hepatitis C virus are usually treated with peginterferon and ribavirin to prevent progressive hepatic fibrosis, cirrhosis, and hepatocellular carcinoma. (cdc.gov)
Without appropriate diagnosis, referral for care and treatment, up to a third of individuals with chronic viral hepatitis will die of liver cancer or cirrhosis. (who.int)
An estimated 78% of all cases of liver cancer and 57% of those of cirrhosis are caused by chronic hepatitis B or C virus infections. (who.int)
Peginterferon alpha and ribavirin combination therapy in patients with hepatitis C virus-related liver cirrhosis. (bvsalud.org)

The treatment of insulin resistance by decreasing hyperinsulinemia could improve sustained response rates in patients with chronic hepatitis C treated with peginterferon plus ribavirin. (isciii.es)

Monotherapy with pegylated interferon, ribavirin, or any direct-acting antiviral agent (eg, simeprevir, sofosbuvir) is not recommended, due to their lack of efficacy. (medscape.com)
Peginterferon plus ribavirin is the recommended treatment for chronic hepatitis C. However, ribavirin monotherapy may be considered for some patients. (regionh.dk)
Dyk ned i forskningsemnerne om 'Ribavirin monotherapy for chronic hepatitis C'. Sammen danner de et unikt fingeraftryk. (regionh.dk)
Ribavirin monotherapy for chronic hepatitis C . Cochrane Database of Systematic Reviews , (4), CD005527. (regionh.dk)
Ribavirin targeted eIF4E in AML patients in monotherapy and combination studies and this corresponded to objective clinical responses including complete remissions. (wikipedia.org)

Higher incidence of side-effects was seen in Group-A. Conclusion:Pegylated interferon plus Ribavirin showed 94% SVR in 2 years. (edu.pk)

Hepatitis C is a liver disease resulting from HCV, a virus that spreads through direct contact with blood. (medicalnewstoday.com)
To protect their liver from further harm, HCV-positive patients should be advised to avoid alcohol, 7 , 8 not to start taking any new medicines, including over-the-counter and herbal medicines, without checking with their doctor and to get vaccinated against hepatitis A if liver disease is found to be present. (aafp.org)
The term viral hepatitis , however, usually is applied only to those cases of liver disease caused by the hepatitis viruses. (britannica.com)
Liver Blood Tests Liver tests are blood tests that represent a noninvasive way to screen for the presence of liver disease (for example, viral hepatitis in donated blood) and to measure the severity and progress. (msdmanuals.com)

Patients were treated with pegylated interferon alfa-2b 1.5 μg/kg per week subcutaneously plus oral ribavirin 800 mg/d for patients with genotypes 2 and 3 for 24 wk. (wjgnet.com)
The study aimed to assess results of response guided therapy with pegylated interferon α (PegINFα) and ribavirin in HCV infected patients in different genotypes. (helsinki.fi)
Based on the treatment response and the low cost, PegINFα + ribavirin combination therapy should still be considered as a cost-effective treatment option for these genotypes. (helsinki.fi)
Sofosbuvir (also known as Sovaldi) is recommended as a possible treatment for adults with some types (called genotypes) of chronic hepatitis C. It is taken with other drugs (peginterferon alfa and ribavirin, or ribavirin alone). (nice.org.uk)
Hepatitis C is an enveloped virus, and the RNA also lacks a proofreading ability after replication, which results in mutations coding for many genotypes within the host. (bartleby.com)
The Global Burden of Hepatitis E Virus Genotypes 1 and 2 in 2005. (who.int)

The enzyme inosine triphosphate pyrophosphatase (ITPase) dephosphorylates ribavirin triphosphate in vitro to ribavirin monophosphate, and ITPase reduced enzymatic activity present in 30% of humans potentiates mutagenesis in hepatitis C virus. (wikipedia.org)

A total of 1121 patients were randomly assigned to treatment and received at least one dose of study medication, consisting of 180 microg of peginterferon alfa-2a once weekly plus daily ribavirin (1000 or 1200 mg, depending on body weight), weekly peginterferon alfa-2a plus daily placebo, or 3 million units of interferon alfa-2b thrice weekly plus daily ribavirin for 48 weeks. (nih.gov)
Ribavirin plasma exposures were approximately 20% lower in subjects with ESRD on HD compared to subjects with normal renal function receiving the standard 1000/1200 mg Copegus daily dose. (hivandhepatitis.com)
Group A received interferon-alpha2a, 4.5 MIU thrice weekly for 6 months, and group B received ribavirin, 1000-1200 mg/day, in combination with the same dose of interferon-alpha2a for 6 months. (ox.ac.uk)

Pharmacokinetic modeling and simulation indicates that a dose of 200 mg daily in patients with severe renal impairment and a dose of 200 mg daily alternating with 400 mg the following day in patients with moderate renal impairment will provide plasma ribavirin exposure similar to patients with normal renal function receiving the approved regimen of Copegus. (hivandhepatitis.com)

This patient was treated with sofosbuvir and ribavirin for 12 weeks. (biomedcentral.com)

Seven patients, two with cryoglobulinaemia, vasculitic manifestations and glomerulonephritis (GN), four with MPGN and one with FSGS were treated with a combination of interferon and ribavirin. (qxmd.com)
For hepatitis C, it is used in combination with other medications such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a. (wikipedia.org)
In this former indication the oral (capsule or tablet) form of ribavirin is used in combination with pegylated interferon alfa, including in people coinfected with hepatitis B, HIV and in the pediatric population. (wikipedia.org)
Background & Aims: Combination therapy with pegylated interferon (PEGIFN) and ribavirin has significantly improved virus eradication rate in patients affected by HCV-related chronic hepatitis (C-HC). (unimore.it)
Ribavirin is one of the major agents used in combination therapy with interferon for chronic hepatitis C, but is often associated with hemolytic anemia as a serious adverse event. (elsevierpure.com)
Ribavirin continues to be used in combination with sofosbuvir alone or other combinations. (medscape.com)
BACKGROUND: Preliminary results from combination therapy with interferon-alpha and ribavirin (IFN/Rib) in patients with chronic hepatitis C have been promising, with up to 50% sustained hepatitis C virus (HCV) RNA response. (ox.ac.uk)
CONCLUSIONS: In a group of previous IFN-alpha2a-treated chronic HCV patients we obtained a similar sustained clearance of viremia when retreated either with IFN-alpha2a alone or with a combination of IFN-alpha2a and ribavirin for 6 months. (ox.ac.uk)
OBJECTIVE: To determine whether Asian race is an independent marker for response to antiviral therapy in hepatitis C. METHODS: Data on treatment-naïve patients from a large multicenter study of combination therapy with peginterferon alfa-2a (180 mug SC each week) and ribavirin (800 mg daily) were analyzed retrospectively to identify factors associated with an SVR, defined as an undetectable serum HCV RNA at least 24 wk after completion of therapy. (mcmaster.ca)
7 Direct-acting antivirals can be used alone or in combination with peginterferon plus ribavirin. (cmaj.ca)

Hepatitis C can be acute, meaning that it lasts a short time and then resolves. (medicalnewstoday.com)
Acute hepatitis E is more common than chronic hepatitis E. Acute hepatitis E lasts for a limited time and then goes away. (medicinenet.com)
The signs and symptoms of acute viral hepatitis result from damage to the liver and are similar regardless of the hepatitis virus responsible. (britannica.com)
Complications of acute viral hepatitis include fulminant hepatitis, which is a very severe, rapidly developing form of the disease that results in severe liver failure, impaired kidney function, difficulty in the clotting of blood, and marked changes in neurological function. (britannica.com)
There is no specific treatment for acute hepatitis E, but most people recover completely. (msdmanuals.com)
People with hepatitis E have typical symptoms of acute hepatitis. (msdmanuals.com)

Serum RANTES level influences the response to pegylated interferon and ribavirin therapy in chronic hepatitis C. (bvsalud.org)
Homocysteine levels and sustained virological response to pegylated-interferon alpha2b plus ribavirin therapy for chronic hepatitis C: a prospective study. (unina.it)

My child has hepatitis C. The treatment for it is peginterferon and ribavirin, which have many side effects. (hepmag.com)

An estimated 3.9 million Americans are infected with hepatitis C virus (HCV), and most do not know that they are infected. (aafp.org)
Two recent genomic studies ( here and here) provided insight into observed ethnic disparities in treatment response by identifying a genetic variant in the IL28B gene that is an important predictor of treatment response and spontaneous clearance in patients infected with hepatitis C virus. (cdc.gov)

abstract = "Hepatitis C is a major cause of liver-related morbidity and mortality. (regionh.dk)

Ribavirin is an antiviral medication. (medivacinternational.net)

The primary goal of therapy for patients infected with hepatitis C (HCV) is viral eradication. (medscape.com)

Conclusions: Peginterferon alfa-2b plus weight-based ribavirin is effective and safe in patients who failed interferon alfa/ribavirin therapy. (psu.edu)
CONCLUSIONS: Asians are more likely to achieve an SVR to treatment with peginterferon alfa-2a and ribavirin than whites with chronic hepatitis C, suggesting a genetic influence on the antiviral response. (mcmaster.ca)
CONCLUSIONS: In patients with chronic hepatitis C, homocysteine levels are associated with the outcome of pegylated-IFNalpha plus ribavirin treatment, while polymorphisms of MTHFR are not. (unina.it)

A GWAS of change in hemoglobin levels during ribavirin treatment identified inosine triphosphatase (ITPA) variants that can protect against ribavirin-induced anemia. (cdc.gov)
Association between inosine triphosphatase rs1127354 polymorphisms and ribavirin-induced anaemia and outcome in hepatitis C virus-infected patients: A meta-analysis. (cdc.gov)

Average daily ribavirin dose was 200-800 mg. (qxmd.com)

1 In the absence of effective preventive measures and considering the long-term infectious nature of the disease, it is important that those who test positive for hepatitis C antibody (anti-HCV) be advised on how they can avoid infecting others. (aafp.org)
Participants 6 years and older testing positive for antibody to hepatitis C virus (anti-HCV) (LBXHC) are sent a report of findings (ROF) letter informing them of their HCV test result and encouraging them to follow up with a health care provider to determine if any other tests or procedures are needed. (cdc.gov)
They were negative for anti-HCV an- duce sustained virological eradication This matched case-control study com- tibody, hepatitis B surface antigen and is only expected to be achieved in up to prised 93 patients chronically infected HIV antibody and had normal levels of 60% of Egyptian patients infected with with HCV-4 followed up in the Gas- liver enzymes. (who.int)

In patients with chronic hepatitis C, once-weekly peginterferon alfa-2a plus ribavirin was tolerated as well as interferon alfa-2b plus ribavirin and produced significant improvements in the rate of sustained virologic response, as compared with interferon alfa-2b plus ribavirin or peginterferon alfa-2a alone. (nih.gov)
Background & Aims: Treatment with peginterferon alfa and ribavirin produces a sustained virologic response (SVR) in approximately 60% of hepatitis C virus (HCV)-infected patients. (psu.edu)

cerning efficacy and safety of ribavirin are scarce ( 12 ). (cdc.gov)
We compared the efficacy and safety of peginterferon alfa-2a plus ribavirin, interferon alfa-2b plus ribavirin, and peginterferon alfa-2a alone in the initial treatment of chronic hepatitis C. (nih.gov)
To study the safety and efficacy of pegylated interferon alfa-2b, indigenously developed in India, plus ribavirin in treatment of hepatitis C virus (HCV). (wjgnet.com)
Following the demonstration of a more potent antiviral effect in terms of sustained virological response rates in Phase III randomized trials, pegylated IFN coupled with ribavirin has become the standard of care for chronic hepatitis C. Currently, two forms of pegylated IFN exist (α2a and α2b), which differ significantly in terms of pharmacokinetics and dynamics, is whether these peculiarities translate into different efficacy rates being still being debated. (hunimed.eu)
To evaluate the efficacy of PEG-Interferon alpha-2a plus weight-based ribavirin doses in patients with these characteristics in a single Italian centre. (unipd.it)
We aimed to evaluate the efficacy and safety of pegylated interferon (PEG-IFN) and ribavirin (RIB) in the treatment of post-OLT HCV recurrence. (elsevierpure.com)
Impact of IL28B gene polymorphism on efficacy and safety of direct acting antivirals in hepatitis C Egyptian patients. (cdc.gov)

Ribavirin comes as a tablet, a capsule and an oral solution (liquid) to take by mouth. (medlineplus.gov)

In summary, hepatitis C promotes insulin resistance and insulin resistance induces steatosis, fibrosis, and interferon resistance. (isciii.es)
Currently, some evidence supports a relationship between insulin resistance and hepatitis C. Indeed, insulin resistance is more often seen in patients with chronic hepatitis C than in weight-matched healthy controls, and correlates with fibrosis progression. (isciii.es)
Hepatitis C virus affects 250 000 to 400 000 Canadians and may lead to progressive liver fibrosis. (cmaj.ca)

The change was based on data from a clinical trial of 50 chronic hepatitis C patients with moderate or severe renal impairment or end-stage renal disease, as well as pharmacokinetic modeling or simulation, according to an FDA announcement this week. (hivandhepatitis.com)

Ribavirin will not treat hepatitis C (a virus that infects the liver and may cause severe liver damage or liver cancer) unless it is taken with another medication. (medlineplus.gov)
Ribavirin is used with an interferon medication such as peginterferon alfa-2a [Pegasys] or peginterferon alpha-2b [PEG-Intron]) to treat hepatitis C in people who have not been treated with an interferon before. (medlineplus.gov)
Ribavirin is used primarily to treat hepatitis C and viral hemorrhagic fevers (which is an orphan indication in most countries). (wikipedia.org)
Doctors do not generally treat hepatitis C during pregnancy. (medicalnewstoday.com)
If doctors can treat hepatitis C successfully before pregnancy, this eliminates the risk of transmission to the fetus. (medicalnewstoday.com)

PEG-IFN alfa-2b treatment for chronic hepatitis C was maintained and no therapy was given for PR. (balkanmedicaljournal.org)

The serum RANTES level is an important determinant influencing the virological response to PEG IFN/RBV therapy in chronic hepatitis C . (bvsalud.org)

the incidence of influenza-like symptoms and depression was lower in the groups receiving peginterferon alfa-2a than in the group receiving interferon alfa-2b plus ribavirin. (nih.gov)
On August 9, 2011, the U.S. Food and Drug Administration (FDA) approved changes to the product label information for pegylated interferon alfa-2a (Pegasys) plus the Copegus brand of ribavirin, reflecting new dose recommendations for people with impaired kidney function. (hivandhepatitis.com)
Dive into the research topics of 'Peginterferon alfa-2a and ribavirin in latino and non-latino whites with hepatitis C'. Together they form a unique fingerprint. (johnshopkins.edu)
Peginterferon alfa-2a and ribavirin in latino and non-latino whites with hepatitis C . New England Journal of Medicine , 360 (3), 257-267. (johnshopkins.edu)

Two treatment regimens are available: traditional dual therapy (interferon + ribavirin) used since 2010 and direct-acting antivirals (DAAs) since the end of 2015. (scirp.org)

Anatomy3

Organisms16

Diseases32

Chemicals and Drugs41

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Psychiatry and Psychology1

Phenomena and Processes10

Technology, Industry, Agriculture1

Information Science4

Named Groups1

Health Care8

Geographicals1

Genotype30

Infection49

Cirrhosis9

Treated with peginterferon1

Monotherapy5

Interferon plus1

Liver disease4

Genotypes6

Potentiates mutagenesis in hepatitis C vir1

1200 mg3

Regimen1

Sofosbuvir and Ribavirin1

Combination10

Acute6

Response to pegylated2

Peginterferon and ribavirin1

Infected with hepatitis C vir2

Abstract1

Antiviral medication1

Patients infected with hepatitis1

Conclusions3

Inosine2

Daily ribavirin1

Antibody3

Virologic response2

Efficacy7

Capsule1

Fibrosis3

Chronic hepatitis C patients1

Treat hepatitis5

Treatment for chronic hepatitis1

Virological1

Alfa-2a4

Direct-acting ant1