• tumor
  • External radiotherapy (RT) has been selectively used for patients with the localized hepatic tumor(s) refractory to the above treatment options. (clinicaltrials.gov)
  • Originally, there was concern that PVE could promote tumor growth and increase recurrence rates, however a systematic review has found that there was no significant difference observed in postoperative hepatic recurrence or 3 and 5 year overall survival rates. (wikipedia.org)
  • It consists of injecting small radioactive beads loaded with yttrium-90 into the hepatic artery feeding the hepatic lobe in which the tumor is located. (wikipedia.org)
  • While PVE is "bland", utilizing simple microspheres, RL is a form of radioembolization, which confers additional benefits: it contemporarily induces necrosis treating the tumor (minimizing the risk of progression) and can potentially convert patients with portal vein thrombosis to resectable status. (wikipedia.org)
  • Radiation lobectomy: after gaining femoral artery access and advancing a catheter in the right hepatic artery (most often), 90Y microspheres are infused in a lobar fashion, optimizing tumor and parenchymal coverage. (wikipedia.org)
  • Therefore, delivery of radioembolic particles through the branch of the hepatic artery supplying a tumor will preferentially lead to deposition of the particles in the tumor, while sparing normal liver from harmful side effects. (wikipedia.org)
  • Other indications for treatment are those who have unresectable HCC, HCC with partial or branch portal vein thrombosis, unresectable cholangiocarcinoma, metastatic neuroendocrine tumors, HCC patients who are currently ineligible for liver transplant, Y-90 can be used to decreases tumor size allowing patients to be candidates. (wikipedia.org)
  • Contrast computed tomography and/or contrast-enhanced magnetic resonance imaging of the liver is required to assess tumor and normal liver volumes, portal vein status, and extrahepatic tumor burden. (wikipedia.org)
  • Once the branch of the hepatic artery supplying the tumor is identified and the tip of the catheter is selectively placed within the artery, the 90Y microspheres are infused. (wikipedia.org)
  • Injection of radiotherapeutic materials through the hepatic artery allows for targeted delivery of treatment to a hepatic tumor with significantly reduced damage to surrounding tissue. (wikipedia.org)
  • develop thrombosis
  • A significant proportion of the population has a detectable abnormality, but most of these only develop thrombosis in the presence of an additional risk factor. (wikipedia.org)
  • Congenital thrombophilia refers to inborn conditions (and usually hereditary, in which case "hereditary thrombophilia" may be used) that increase the tendency to develop thrombosis, while, on the other hand, acquired thrombophilia refers to conditions that arise later in life. (wikipedia.org)
  • Forty percent of people with PNH develop thrombosis (a blood clot) at some point in their illness. (wikipedia.org)
  • carry deoxygenated blood
  • The upper two thirds of the esophagus are drained via the esophageal veins, which carry deoxygenated blood from the esophagus to the azygos vein, which in turn drains directly into the superior vena cava. (wikipedia.org)
  • varices
  • Esophageal varices (sometimes spelled oesophageal varices) are extremely dilated sub-mucosal veins in the lower third of the esophagus. (wikipedia.org)
  • These veins have no part in the development of esophageal varices. (wikipedia.org)
  • Dilated submucosal veins are the most prominent histologic feature of esophageal varices. (wikipedia.org)
  • thrombotic
  • The differential diagnoses of intra hepatic infarction include intrahepatic abscess, acute fatty liver of pregnancy, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, ruptured hepatic adenoma, hepatocellular carcinoma and hemangioma. (appliedradiology.com)
  • Ascites
  • Increased portal venous pressure, Hypoproteinaemia, Chronic peritoneal inflammation and infection, Leakage of lymphatic fluid , can be the major causes of ascites. (hpathy.com)
  • Volume resuscitation can also worsen ascites and increase portal pressure. (wikipedia.org)
  • viral
  • Serum analyses are done for evaluating hepatic function, viral load, hematological toxicity, and translational research for angiogenic and inflammatory studies. (clinicaltrials.gov)
  • embolization
  • Portal vein embolization (PVE) is a preoperative procedure performed in interventional radiology to initiate hypertrophy of the anticipated future liver remnant a couple weeks prior to a major liver resection procedure. (wikipedia.org)
  • This is done with the intent of inducing growth in the contralateral hepatic lobe, not dissimilarly from portal vein embolization (PVE). (wikipedia.org)
  • recurrent
  • Here, we report two cases of JAK2V617F positive MPN who also had other thrombophilic conditions and presented with recurrent thrombosis. (hindawi.com)