• Canals of Her
  • The canaliculi join each other to form larger and larger structures, sometimes referred to as the Canals of Hering, which themselves join to form small bile ductules that have an epithelial surface. (wikipedia.org)
  • Drainage
  • In infants with biliary atresia, hepatoportoenterostomy is an alternative method of providing bile drainage. (wikipedia.org)
  • As well, the exact origin and drainage locations of the relevant duct(s) varied greatly between patients. (wikipedia.org)
  • The origin and drainage of these ducts were limited primarily to the right lobe of the liver, but great variation was seen. (wikipedia.org)
  • Often diagnosed by HIDA scan, a bile leak from an accessory bile duct post-op can be treated with a temporary biliary stent[citation needed] to redirect the bile from the liver into the intestine and allow the accessory duct to spontaneously seal itself or using a drainage guided by radiology. (wikipedia.org)
  • A hepatoportoenterostomy or Kasai portoenterostomy is a surgical treatment performed on infants with Type IVb choledochal cyst and biliary atresia to allow for bile drainage. (wikipedia.org)
  • The rationale for this approach is that minute residual bile duct remnants may be present in the fibrous tissue of the porta hepatis and thus provide direct connection with the intrahepatic ductule system to allow bile drainage. (wikipedia.org)
  • If performed before 60 days of age, 80% of children achieve some bile drainage Prognosis is progressively worse the later surgery is done Post-operatively, cholangitis and malabsorption are common Many children with biliary atresia will require liver transplantation despite the attempted surgical repair, although on occasion, it can be delayed until adulthood. (wikipedia.org)
  • Multiple episodes of life-threatening acute cholangitis (infection within the bile ducts) can be seen due to impaired drainage of the bile ducts, which increases the risk of infection. (wikipedia.org)
  • acute
  • Lyase During Acute Cholecystitis-Induced Gallbladder Inflammation. (jove.com)
  • The aim of this study was to investigate whether gallbladder possesses the enzymatic machinery to synthesize H2S, and whether H2S synthesis is changed in gallbladder inflammation during acute acalculous cholecystitis (AC). (jove.com)
  • This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including cholestasis necrosis acute hepatitis and chronic hepatitis of different forms, cirrhosis Effects of Acetaminophen (Tylenol) other rare disorders like focal nodular hyperplasia, Hepatic fibrosis, peliosis hepatis and veno-occlusive disease. (wikipedia.org)
  • porta hepatis
  • It is covered in peritoneum apart from where it attaches the gallbladder and the porta hepatis. (wikipedia.org)
  • The surgery involves exposing the porta hepatis (the area of the liver from which bile should drain) by radical excision of all bile duct tissue up to the liver capsule and attaching a Roux-en-Y loop of jejunum to the exposed liver capsule above the bifurcation of the portal vein creating a portoenterostomy. (wikipedia.org)
  • artery
  • The duct, the branches of the hepatic artery, and the portal vein form the central axis of the portal triad. (wikipedia.org)
  • The liver is connected to two large blood vessels: the hepatic artery and the portal vein. (wikipedia.org)
  • The hepatic artery carries oxygen-rich blood from the aorta, whereas the portal vein carries blood rich in digested nutrients from the entire gastrointestinal tract and also from the spleen and pancreas. (wikipedia.org)
  • cholestasis
  • The two basic distinctions are an obstructive type of cholestasis where there is a mechanical blockage in the duct system that can occur from a gallstone or malignancy, and metabolic types of cholestasis which are disturbances in bile formation that can occur because of genetic defects or acquired as a side effect of many medications. (wikipedia.org)
  • Pruritus is the primary symptom of cholestasis and is thought to be due to interactions of serum bile acids with opioidergic nerves. (wikipedia.org)
  • With a few exceptions, the optimal test for cholestasis would be elevations of serum bile acid levels. (wikipedia.org)
  • Chronic impairment of bile flow due to blockage and dysfunctional bile transport (cholestasis) causes progressive biliary fibrosis and ultimately biliary cirrhosis and liver failure. (wikipedia.org)
  • causes
  • Ischemic causes like damage to the blood supply of the bile ducts. (medindia.net)
  • Inflation of a balloon in the bile duct causes, through the vagus nerve, activation of the brain stem and the insular cortex, prefrontal cortex, and somatosensory cortex. (wikipedia.org)
  • hepatocytes
  • Under a microscope, the individual hepatocytes will have a brownish-green stippled appearance within the cytoplasm, representing bile that cannot get out of the cell. (wikipedia.org)
  • Each lobule is made up of millions of hepatic cells (hepatocytes) which are the basic metabolic cells. (wikipedia.org)
  • opens
  • The uterus from the ovary, and seminal ducts from the testes meet and opens at the genital pore. (wikipedia.org)
  • autoimmune
  • The subgroups of PSC include the following: Classic PSC Small-duct PSC PSC associated with autoimmune hepatitis Play media Nearly half of people with PSC do not have symptoms and are often incidentally discovered to have PSC due to abnormal liver function tests, but a substantial proportion will have debilitating signs and symptoms of the disease. (wikipedia.org)