• enoxaparin
  • NSTEMI Atrial fibrillation Deep-vein thrombosis and pulmonary embolism Cardiopulmonary bypass for heart surgery ECMO circuit for extracorporeal life support Hemofiltration Indwelling central or peripheral venous catheters Heparin and its low-molecular-weight derivatives (e.g., enoxaparin, dalteparin, tinzaparin) are effective in preventing deep vein thromboses and pulmonary emboli in people at risk, but no evidence indicates any one is more effective than the other in preventing mortality. (wikipedia.org)
  • Commonly used low molecular weight heparins are enoxaparin, dalteparin, nadroparin and tinzaparin. (wikipedia.org)
  • patients receivi
  • The first is elevation of serum aminotransferase levels, which has been reported in as many as 80% of patients receiving heparin. (wikipedia.org)
  • The other complication is hyperkalemia, which occurs in 5 to 10% of patients receiving heparin, and is the result of heparin-induced aldosterone suppression. (wikipedia.org)
  • GAGs
  • Heparin and HS are glycosaminoglycans (GAGs), which are linear polysaccharides composed of two basic saccharides: an amino sugar and an uronic acid2,3,4. (sigmaaldrich.com)
  • Three aspects of synthetic mimicking polymers are currently focused on: mimicking anionic sulfate domains of heparin, polymerization of sulfated saccharides and sulfation of natural occurring GAGs. (wikipedia.org)
  • Problems arise when defining hybrid GAGs that contain both 'heparin-like' and 'HS-like' structures. (wikipedia.org)
  • sodium
  • Heparin sodium is extracted porcine intestinal mucosa, white or almost white moderately hygroscopic powder, freely soluble in water. (fuzing.com)
  • batches
  • A child could tell you it's counterfeiting," said Dr. Jawed Fareed, a professor of pathology and pharmacology at Loyola University Chicago, who has been studying batches of heparin since the problems with the drug were discovered. (hughhewitt.com)
  • The raw material for the recalled heparin batches was processed in China from pig's intestines by the American pharmaceutical firm Scientific Protein Laboratories. (wikipedia.org)
  • The raw heparin batches were found to have been cut from 2-60% with the counterfeit substance, and motivation for the adulteration was attributed to a combination of cost effectiveness and a shortage of suitable pigs in China. (wikipedia.org)
  • protein
  • Heparin-binding EGF-like growth factor has been shown to interact with NRD1, Zinc finger and BTB domain-containing protein 16 and BAG1. (wikipedia.org)
  • However it is chemically distinct from heparin, has different protein binding properties and thus has little cross-reactivity in heparin-intolerant patients. (wikipedia.org)
  • occur
  • In those receiving heparin through an intravenous infusion, a complex of symptoms ("systemic reaction") may occur when the infusion is started. (wikipedia.org)
  • drip
  • heparin drip and bleeding? (allnurses.com)
  • In regards to heparin drip, if patient was bleeding from a unidentified source, how long will it take to manifest into symptoms such as hematuria? (allnurses.com)
  • PTTs are always measured when a patient's on a heparin drip, so you'd know what the platelets are. (allnurses.com)
  • ingredient
  • The U.S. Food and Drug Administration was quoted as stating that at least 81 deaths were believed to be linked to a raw heparin ingredient imported from the People's Republic of China, and that they had also received 785 reports of serious injuries associated with the drug's use. (wikipedia.org)
  • CZ-SPL makes a key ingredient, what in the pharmaceutical business is called an active pharmaceutical ingredient, or API, for a drug called heparin, a blood thinner that is widely used by kidney-dialysis and postsurgical patients to prevent blood clots. (wikipedia.org)
  • platelets
  • Human trials suggest that policosanol makes blood platelets more slippery, an action that could potentiate the blood-thinning effects of heparin, possibly causing a risk of abnormal bleeding episodes. (medicalcityhospital.com)
  • Drugs.com further mentions that patients should not use Heparin when suffering from uncontrolled bleeding or a very low level of blood platelets. (reference.com)
  • contaminant
  • The F.D.A. has said it has the world's top heparin chemists working on the contaminant at two F.D.A. laboratories, three American universities and several European academic institutions. (hughhewitt.com)
  • tissue
  • While heparin does not break down clots that have already formed (unlike tissue plasminogen activator), it allows the body's natural clot lysis mechanisms to work normally to break down clots that have formed. (wikipedia.org)
  • Shape memory heparin mimicking polymers can be used to create devices that extract hemorrhaging tissue. (wikipedia.org)
  • doses
  • Most of the reactions reported in the United States occurred in dialysis centers among people given high initial doses of heparin, the report found. (washingtonpost.com)