Because of their broad spectrum antimicrobial activity they are widely used both as food preservatives and as next generation therapeutics [PMID: 25186038]. (bicnirrh.res.in)
beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal surfaces. (lookformedical.com)
beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that may play a role in mucosal defenses of several organs. (lookformedical.com)
HCAP-181
The gene product is synthesized as a propeptide and is referred to as human cationic antimicrobial peptide-18 (hCAP-18/LL-37). (biomedcentral.com)
Cationic1
Antimicrobial peptides (AMPs) are small amphipathic and cationic polypeptides with high therapeutic potential against various microorganisms containing drug-resistant strains. (bvsalud.org)
In the current research, the amino-acid sequence of human cathelicidin LL-37 (2-31) and Human beta-defensin (hBD)-129 were combined, and the fusion protein was evaluated by bioinformatics tool. (bvsalud.org)
Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. (lookformedical.com)
In this study, we characterized the expression of HBD-1 and HBD-2 mRNAs within the major salivary glands, tongue, gingiva, and buccal mucosa and detected beta-defensin peptides in salivary secretions. (lookformedical.com)
Intestinal2
Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. (bicnirrh.res.in)
In this study, we explored the role of a novel antibacterial peptide Bombyx mori gloverin A2 (BMGlvA2) in alleviating ETEC-induced inflammation and intestinal epithelium disruption in mice. (biomedcentral.com)
AMPs1
The antimicrobial peptides (AMPs) are a group of immune-related peptides/ proteins that protect the host from microbial infections [ 11 , 12 , 13 ]. (biomedcentral.com)
Antibacterial activity1
The family is made up of four alpha-helical antimicrobial peptides, clavanins A, B, C and D. The tunicate peptides resemble magainins in size, primary sequence and antibacterial activity. (bicnirrh.res.in)
Genes2
In the current study, the transcriptome of C. splendens was sequenced, and de novo assembled to identify the presence of antimicrobial peptide genes. (bvsalud.org)
The other gene, named RBD-2, was homologous to the HBD-2 and bovine tracheal antimicrobial peptide (TAP) genes. (lookformedical.com)
Secretions1
Brevinins are antimicrobial peptides obtained from the skin secretions of frogs [PMID: 22307792]. (bicnirrh.res.in)
Homologous2
These peptides have variable C-terminal domains responsible for their antimicrobial and immunomodulatory activities and a highly conserved N-terminal pre-pro region homologous to cathelin. (bvsalud.org)
Fragments of the LL-37 domain can give us clues about how homologous cathelicidins, in general, induce an immune response. (bvsalud.org)
Exhibit2
This family of peptide exhibit no structural similarity with other antimicrobial peptides from frogs skin [PMID: 15207717]. (bicnirrh.res.in)
The pepides exhibit antimicrobial and insecticidal properties [PMID:11792701]. (bicnirrh.res.in)
Polypeptide2
Host defense peptides (HDPs) are naturally occurring polypeptide sequences that, in addition to being active against bacteria, fungi, viruses, and other parasites, may stimulate immunomodulatory responses. (bvsalud.org)
Cathelicidin-BF (BF-30), as a 30-mer polypeptide isolated from Bungarus fasciatus serum with a secondary structure of amphipathic α-helical conformation, exhibits outstanding anti-microbial activities [ 1 , 2 ]. (jcancer.org)
Structural1
Other cathelicidins also share structural and functional characteristics with the LL-37 domain, suggesting that these fragments may be responsible for interaction between these peptides and receptors in humans. (bvsalud.org)
Humans1
Family of antimicrobial peptides that have been identified in humans, animals, and plants. (lookformedical.com)
Innate2
Although cathelicidins are the major components of innate immunity, the molecular basis by which they induce an immune response is still unclear. (bvsalud.org)
The presence of alpha-helical antimicrobial peptides in the haemocytes of a urochordate suggests that such peptides are primeval effectors of innate immunity in the vertebrate lineage [PMID: 9001389]. (bicnirrh.res.in)
Sequences1
The precursor sequences of a number of antimicrobial peptides secreted by neutrophils (polymorphonuclear leukocytes) upon activation have been found to be evolutionarily related and are collectively known as cathelicidins [PMID: 7589491]. (bicnirrh.res.in)
Antibiotics1
Our results suggested a novel function of the conventional antibacterial peptides, and the anti-bacterial and anti-inflammatory properties of BMGlvA2 may allow it a potential substitute for conventionally used antibiotics or drugs. (biomedcentral.com)
Synthetic2
Though the synthetic CATH-2 caused hemolysis of human RBC, it also exhibited antimicrobial activity against E. coli, S. aureus, and B. cereus. (bvsalud.org)
Synthetic clavanin A displays comparable antimicrobial activity to magainins and cecropins. (bicnirrh.res.in)
Family4
Ascaphin family of antibacterial peptides are secreted from the frog Ascaphus truei. (bicnirrh.res.in)
This family of antibacterial peptides are secreted from the granular dorsal glands of Litoria aurea (Green and golden bell frog), Litoria raniformis (Southern bell frog), Litoria citropa (Australian blue mountains tree frog) and frogs from genus Uperoleia. (bicnirrh.res.in)
They are a part of the FSAP peptide family. (bicnirrh.res.in)
Cupiennins are a family of antimicrobial peptides isolated from the venom of Cupiennius salei. (bicnirrh.res.in)
These peptides have strong antimicrobial and some anti-fungal activity and has homology to abaecin which is the largest proline-rich antimicrobial peptide isolated from European bumblebee Bombus pascuorum [PMID: 9219367]. (bicnirrh.res.in)
Identify1
Western immunoblotting, liquid chromatography, and mass spectrometry were used to identify the HBD-1 and HBD-2 peptides in human saliva. (lookformedical.com)
Major1
CAMPSign is a tool for identification of antimicrobial peptides belonging to one of the 45 major AMP families present in CAMP R3 . (bicnirrh.res.in)
Active1
Because ASL [Cl(-)] is low in normal and mutant mice, salt-sensitive antimicrobial factors, including MBD-1, may be normally active. (lookformedical.com)
Results1
Docking simulation results revealed that this peptide could bind to the LPS binding site of MD-2, which may prevent LPS from entering the MD-2 binding pocket, and trigger TLR4 signaling pathway. (bvsalud.org)