• wherein
  • 3. The heart valve prosthesis of claim 2 wherein the stent includes a plurality of apertures adapted for receiving sutures for mounting the valve means to the stent. (google.com)
  • 4. The heart valve prosthesis of claim 3 wherein the solid plate of the stent comprises an elongated substantially flat plate which had been bent to meet at two opposite edges, said edges having been welded together with an overlying plate. (google.com)
  • 6. The heart valve prosthesis of claim 5 wherein the first and second cloth are embedded into the sewing ring and stent support ring, respectively, by a plastic molding process. (google.com)
  • 7. The heart valve prosthesis of claim 6 wherein the first and second cloth both comprise poly acetate material. (google.com)
  • 5. A system as in claim 1 , further comprising a pair of elongate elements extensible from a distal end of the external tube, wherein each element is adapted to capture a valve leaflet. (google.com)
  • 7. A system as in claim 5 , wherein each elongate element has a distal extremity adapted to capture a valve leaflet. (google.com)
  • wherein a portion of the inner surface of one cusp is in a facing relationship with a portion of the inner surface of another cusp adjacent the longitudinal suture line when the valve is open. (google.com)
  • 5 . The heart valve of claim 4 , wherein the inner surfaces of adjacent cusps are held together toward the out-flow end of the valve so that the cusps are biased partially closed even when the valve is generally open. (google.com)
  • 8 . The method of claim 7 , wherein a portion of the inner face of each leaflet is in a facing relationship with a portion of the inner face of another leaflet at the out-flow end of the valve so that the adjacent leaflets are partially closed. (google.com)
  • 2. A heart valve leaflet fastener as in claim 1 , further comprising at least one central core wherein said arms project from said core. (google.ca)
  • 5. A heart valve leaf fastener as in claim 4 , wherein each pair of prongs projects from a disk. (google.ca)
  • 8. The device of claim 7 , further comprising a second tube for insertion through a patient's vasculature and into a chamber of a heart wherein the elongate elements are within the second tube. (google.ca)
  • 10. The device of claim 7 , wherein the elongate elements are adapted for connection to a vacuum for grasping the at least two valve leaflets. (google.ca)
  • stent
  • When the heart valve prosthesis is as implanted into the heart, the threads of the sewing ring and of the stent support ring interlock, and there are no plastic or metal surfaces, uncovered by biocompatible fabric, to be exposed to blood flow. (google.com)
  • leaflet
  • After attemping to design a bi-leaflet artificial heart valve, Dr. Albert Starr (born 1926) and engineer M. Lowell Edwards (1898-1982) abandoned the idea of trying to replicate a natural looking valve. (si.edu)
  • A heart valve prosthesis includes an annular body that has a fluid passageway and at least one rigid leaflet that is pivotally mounted in the passageway of the body. (google.com)
  • The heart valve prosthesis has a biasing mechanism that is connected to the body and leaflet and is configured to exert a force on the leaflet to move the leaflet to the closed position before a second fluid pressure exerted on an outflow surface of the leaflet exceeds a first fluid pressure exerted on an inflow surface of the leaflet. (google.com)
  • One popular design for a mechanical heart valve prosthesis includes an annular valve body in which a pair of opposed leaflet occluders are pivotally mounted. (google.com)
  • Once the mitral valve is accessed, repair procedures include annuloplasty and, more recently, suturing of the free edge of the anterior leaflet to the free edge of the back leaflet where the mitral insufficiency occurs. (google.com)
  • Each of the leaflets is adapted to flex inwardly into and out of engagement with another leaflet so as to close and open the valve in response to force by blood pressure. (google.com)
  • passageway
  • In a preferred embodiment, the prosthesis is formed of a base having a blood passageway and dual leaflets pivotally secured to the base to regulate the flow of blood through the passageway. (google.com)
  • A device to provide body fluid flow control in the form of a valve to be located within a duct or passageway. (google.ca)
  • Bulk resilience about a passageway in a valve body provides the mechanism for controlled flow. (google.ca)
  • a valve support about the valve body and attached to the valve body and to the resilient seal, the passage being in communication with the passageway extending longitudinally through the frame. (google.ca)
  • mechanism
  • attaching a replacement new heart valve prosthesis comprising a valve mechanism and integral suturing ring to the surgically attached suturing ring by suturing the integral suturing ring to the surgically attached suturing ring. (google.es)
  • suture
  • 6 . The heart valve of claim 4 additionally comprising suture reinforcements. (google.com)
  • They are made of a metal ring covered by an ePTFE fabric, into which the suture threads are stitched in order to hold the valve in place. (wikipedia.org)
  • clots
  • These blood clots are referred to as thrombosis if they adhere to the heart valve. (google.com)
  • If the clots float away from the valve where they can occlude blood flow to another part of the body, the clots are referred to as thromboembolism. (google.com)
  • Caged ball valves have a high tendency to form blood clots, so the patient must have a high degree of anti-coagulation, usually with a target INR of 2.5-3.5. (wikipedia.org)
  • Because blood clots do not easily form on it, it is often advisable to line a blood-contacting prosthesis with this material in order to reduce the risk of thrombosis. (wikipedia.org)
  • blood
  • Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. (icdlist.com)
  • In a condition known as mitral insufficiency, the mitral valve does not completely shut, and does not prevent the back-flow of blood to the left atrium from the left ventricle. (google.com)
  • The patient is then placed under extra-corporal blood circulation while the heart is stopped, and the heart chambers are opened to gain access to the mitral valve, usually through the left atrium. (google.com)
  • Natural heart valves are evolved to forms that perform the functional requirement of inducing unidirectional blood flow through the valve structure from one chamber of the heart to another. (wikipedia.org)
  • Their main purpose is to maintain unimpeded forward flow through the heart and from the heart into the major blood vessels connected to the heart, the pulmonary artery and the aorta. (wikipedia.org)
  • citation needed] However, current mechanical heart valves all require lifelong treatment with anticoagulants (blood thinners), e.g. warfarin, which requires monthly blood tests to monitor. (wikipedia.org)
  • Tissue heart valves, in contrast, do not require the use of anticoagulant drugs due to the improved blood flow dynamics resulting in less red cell damage and hence less clot formation. (wikipedia.org)
  • When blood pressure in the chamber of the heart exceeds that of the pressure on the outside of the chamber the ball is pushed against the cage and allows blood to flow. (wikipedia.org)
  • The metal ring holds, by means of two metal supports, a disc which opens and closes as the heart pumps blood through the valve. (wikipedia.org)
  • These blood thinners hold an inherent risk for severe bleeding episodes, which affects both professional and leisure activities and the majority of patients opt for mechanical valves for this reason. (wikipedia.org)
  • The clinic established by Amosov, produced about 7000 lung resections, more than 95000 operations for heart diseases, including about 36,000 operations with extra-corporeal blood circulation. (wikipedia.org)
  • Each year, the institute fulfilled about 3000 heart operations, including over 1500 - with extra-corporeal blood circulation. (wikipedia.org)
  • She joined the NIH National Heart Institute (now the National Heart, Lung, and Blood Institute) in nearby Bethesda, Maryland, in 1958 under the mentorship of Dr. Andrew G. Morrow. (wikipedia.org)
  • It occurs when the heart muscle, or myocardium, receives insufficient blood flow. (wikipedia.org)
  • Anemia vasoconstricts the periphery so that red blood cells can work internally on vital organs such as the heart, brain, etc., thus causing lack of oxygen to the periphery. (wikipedia.org)
  • surgical treatment
  • This Institute was the first to conduct surgical treatment of heart diseases in the Ukrainian SSR (since 1955), the Institute began to conduct operations with extracorporeal circulation (1958), and mitral valve replacements (1963). (wikipedia.org)
  • Amosov elaborated a number of new methods of surgical treatment of heart lesions, the original model of heart-lung machine. (wikipedia.org)
  • His work on the surgical treatment of heart diseases won a State Prize of Ukraine (1988) gold medals (1967, 1982) and Silver Medal (1978) of the Exhibition of Economic Achievements of the USSR. (wikipedia.org)