Loading...



  • hypertension
  • Since the advent of effective treatment strategies for heart attackin the 1970's, research into the causative factors of heart conditions and ways to refine thetreatment options have been proceeding at a very rapid pace.Along with the knowledge about the pathological process leading to the heart attack (In Frenchattaque cardiaque)came the information about the risk factors - primarily diabetes,hypertension, hypercholesterolemia and smoking. (slideshare.net)
  • Hypertension, obesity, metabolic syndrome, and sedentary lifestyle have been identified as important risk factors for diverse types of heart disease including HFpEF. (wikipedia.org)
  • Conditions, such as hypertension, that encourage increased left ventricular afterload can lead to structural changes in the heart on a gross, as well as a microscopic level. (wikipedia.org)
  • Inhibition of aldosterone synthase is currently being investigated as a medical treatment for hypertension, heart failure, and renal disorders. (wikipedia.org)
  • Cardiology
  • Dr. Raul L. Lapitan, president of the Philippine Heart Association 2016-2017, completed his medical degree at the Far Eastern University-Dr. Nicanor Reyes Medical Foundation Institute of Medicine and finished his Fellowship in Cardiology at the Makati Medical Center. (inquirer.net)
  • These data are interesting," said Dr. Clyde W. Yancy , cardiology chief at Northwestern University in Chicago and a former American Heart Association president. (go.com)
  • U.S. News & World Report consistently ranks Seattle Children's cardiology and heart surgery program among the best in the country. (seattlechildrens.org)
  • A recent study published in the Journal of the American College of Cardiology found that Abbott's sensor reduced hospitalizations due to heart failure by 46 percent and cut patient medical costs by $7,000 over the following six months. (washingtonexaminer.com)
  • patients
  • The PARADIGM-HF Trial, the largest heart failure trial ever conducted, showed that patients with HF-rEF who were given sacubitril/valsartan were more likely to be alive and less likely to have been hospitalized for sudden deterioration of their heart failure than those given the ACE inhibitor enalapril. (inquirer.net)
  • The availability of a novel, proven-effective treatment for heart failure is welcome news as this novel treatment can improve the quality of life and survival of Filipino patients suffering from this chronic debilitating and life-threatening condition. (inquirer.net)
  • However, the pooled findings are from only 198 patients with chronic, stable heart failure , so they hardly provide the final word on treating the disorder with hormonal supplements, the study's lead author said. (go.com)
  • The observed improvements need to be reproduced in larger numbers of patients before testosterone can be recommended as therapy, said Dr. Justin Z. Ezekowitz , director of the Heart Function Clinic at the University of Alberta in Edmonton, Canada. (go.com)
  • We don't want patients and their loved ones rushing to buy testosterone supplements online, or physicians to misinterpret the findings," said Ezekowitz, who led the meta-analysis published today in the American Heart Association's journal Circulation Heart Failure. (go.com)
  • Heart failure cells are siderophages (hemosiderin-containing macrophages) generated in the alveoli of patients with left heart failure or chronic pulmonary edema, when the high pulmonary blood pressure causes red cells to pass through the vascular wall. (wikipedia.org)
  • Our Heart Failure Program provides coordinated and comprehensive care for more than 350 patients each year with cardiomyopathy and other types of heart failure . (seattlechildrens.org)
  • Weight gain of more than 2 pounds is associated with admission to the hospital for heart failure Sodium restriction - excessive sodium intake may precipitate or exacerbate heart failure, thus a "no added salt" diet (60-100 mmol total daily intake) is recommended for patients with CHF. (wikipedia.org)
  • According to a review in 2009, there is apparently no evidence of benefit of fluid restriction in patients with clinically stable heart failure otherwise receiving optimal pharmacological treatment. (wikipedia.org)
  • Unless contraindicated or not tolerated, ACE inhibitor (ACE) therapy is recommended for all patients with systolic heart failure, irrespective of symptomatic severity or blood pressure. (wikipedia.org)
  • A new study suggests Americans with heart failure may benefit less from recommended medications than patients in other countries. (ibtimes.com)
  • It could be a question of different use of medications or devices to control heart failure, or it could be a chance finding because only one study included a large proportion of U.S. patients, the researchers write. (ibtimes.com)
  • AstraZeneca finally convinced the FDA the reason for the poorer results in North America might be related to the fact that aspirin interferes with Brilinta, and aspirin is more commonly used by heart patients in the U.S. than in Europe. (ibtimes.com)
  • Physicians need a way to identify complications linked to heart failure in their patients before they occur. (washingtonexaminer.com)
  • Today, when patients are diagnosed with heart failure, they usually receive medication and are instructed to consume less sodium and drink fewer fluids. (washingtonexaminer.com)
  • Research shows that patients with heart failure struggle to keep doctor's appointments, don't feel comfortable with their physicians, and often suffer from neurological problems like confusion or short-term memory loss. (washingtonexaminer.com)
  • Common types of medications that are prescribed for heart failure patients include ACE inhibitors, vasodilators, beta blockers, aspirin, calcium channel blockers, and cholesterol lowering medications such as statins. (wikipedia.org)
  • Patients with heart pumping problems will use a different medication combination than those who are experiencing problems with the heart's ability to fill properly during diastole. (wikipedia.org)
  • The National Heart Failure Audit (April 2015-March 2016), published on August 10, 2017, reported that mortality among patients admitted to hospital had fallen to 8.9% compared to 9.6% reported in the previous audit. (wikipedia.org)
  • It also reported that the number of patients seen by specialist heart failure nurses remained high at 80%, and that 90% of patients were recorded as having an up to date echocardiogram. (wikipedia.org)
  • Histologically, Mybpc3-targeted knock-out hearts display structural rearrangements with cardiac myocyte disarray and increased interstitial fibrosis similar to patients with hypertrophic cardiomyopathy, without obvious alterations in shape or size of single cardiac myocytes. (wikipedia.org)
  • pulmonary
  • Diastole is the cardiac cycle phase during which the heart is relaxing and filling with incoming blood that is being returned from the body through the inferior (IVC) and superior (SVC) venae cavae to the right atrium and from lungs through pulmonary veins to the left atrium. (wikipedia.org)
  • Diuretics
  • Several classes are used, with combinations reserved for severe heart failure: Loop diuretics (e.g. furosemide, bumetanide) - most commonly used class in CHF, usually for moderate CHF Thiazide diuretics (e.g. hydrochlorothiazide, chlorthalidone, chlorthiazide) - may be useful for mild CHF, but typically used in severe CHF in combination with loop diuretics, resulting in a synergistic effect. (wikipedia.org)
  • Management consists of propping up the head of the patient, giving oxygen to correct hypoxemia, administering morphine, diuretics like furosemide, addition of an ACE inhibitor, use of nitrates and use of digoxin if indicated for the heart failure and if arrhythmic. (wikipedia.org)
  • cardiovascular
  • Abuse of testosterone, a steroid hormone that helps athletes and bodybuilders bulk up, has been associated with cardiovascular disease, increased risk of heart attack, and mood changes, as well as prostate cancer. (go.com)
  • disease
  • Heart failure is a major human disease that afflicts millions of people worldwide. (keystonesymposia.org)
  • A ventricular assist device or occasionally a heart transplant may be recommended in those with severe disease despite all other measures. (wikipedia.org)
  • And, testosterone supplementation has been associated with better cholesterol levels among men with heart disease, Ezekowitz and his colleagues noted in their study. (go.com)
  • In otherwords, the earlier data revealed only the part of the case load.A lot of effort is invested on methods which detect risk factors, disease of the coronary (heart)arteries, abnormal heart muscle functioning, all at a very early stage and in a non-invasivemanner. (slideshare.net)
  • Initially, this helps compensate for heart failure by maintaining blood pressure and perfusion, but places further strain on the myocardium, increasing coronary perfusion requirements, which can lead to worsening of ischemic heart disease. (wikipedia.org)
  • In 2016, the All Party Parliamentary Group on Heart Disease, chaired by Stuart Andrew MP, held an inquiry into living with heart failure. (wikipedia.org)
  • Jo Myong-rok, 82, North Korean military official, First Vice-Chairman of the National Defense Commission (since 2009), heart disease. (wikipedia.org)
  • workload
  • Angiotensin-converting enzyme (ACE) inhibitors, the current first-line treatment, widen blood vessels to lower blood pressure, improve blood flow and decrease the workload on the heart. (inquirer.net)
  • Over time these increases in workload will produce changes to the heart itself: The heart of a person with heart failure may have a reduced force of contraction due to overloading of the ventricle. (wikipedia.org)
  • This helps restore blood pressure but also increases the total peripheral resistance, increasing the workload of the heart. (wikipedia.org)
  • muscle
  • It typically results from narrowed arteries (atherosclerosis), heart attack, heart valve diseases or infections that weaken the heart muscle. (go.com)
  • There is a lot of interest in the role ofstem cells in the repair of dead heart muscle cells. (slideshare.net)
  • In heart failure, this mechanism fails, as the ventricle is loaded with blood to the point where heart muscle contraction becomes less efficient. (wikipedia.org)
  • This is due to reduced ability to cross-link actin and myosin filaments in over-stretched heart muscle. (wikipedia.org)
  • This is caused by the terminally differentiated heart muscle fibers increasing in size in an attempt to improve contractility. (wikipedia.org)
  • Other well recognized precipitating factors include anemia and hyperthyroidism which place additional strain on the heart muscle. (wikipedia.org)
  • This may be caused by congenital defect or by another condition that damages or overloads the heart muscle. (dmoztools.net)
  • This isoform is expressed exclusively in heart muscle during human and mouse development, and is distinct from those expressed in slow skeletal muscle (MYBPC1) and fast skeletal muscle (MYBPC2). (wikipedia.org)
  • severe
  • The condition is caused by severe congestion of multiple organs by fluid that is inadequately circulated by the failing heart. (wikipedia.org)
  • Diastole
  • A reduced stroke volume may occur as a result of a failure of systole, diastole or both. (wikipedia.org)
  • when myocytes fail to relax appropriately, myosin cross bridges remain intact and generate tension throughout diastole and thus increase stress on the heart. (wikipedia.org)
  • ventricle
  • the aorta originates from the right ventricle, so most of the blood returning to the heart from the body is pumped back out without first going to the lungs. (slideshare.net)
  • diseases
  • 1. Cutting Edge Solutions for Heart ProblemsIt is common knowledge that heart diseases account for a significant amount of deaths andlimitation of the quality of life. (slideshare.net)
  • Consequently, due to effective drugs andcontrol of the risk factors, a decrease in the load of heart diseases was expected. (slideshare.net)
  • reduction
  • The increase in ventricular volume also causes a reduction in stroke volume due to mechanical and inefficient contraction of the heart. (wikipedia.org)
  • aldosterone
  • The chronically high levels of circulating neuroendocrine hormones such as catecholamines, renin, angiotensin, and aldosterone affect the myocardium directly, causing structural remodelling of the heart over the long term. (wikipedia.org)
  • Adverse effects of aldosterone occur in the heart and brain, due to changes in water retention and excretion of sodium and potassium. (wikipedia.org)
  • manifest
  • Ischemia may manifest in distinct ways, either as a result of increasing tissue oxygen demand, or diminished ability of the heart to supply oxygen to the tissue. (wikipedia.org)
  • blood
  • When a person has heart failure, the heart cannot pump strongly enough to supply blood to the body, allowing fluids to build up in the lungs, arms and legs. (go.com)
  • This increases the risk of cardiac arrest (specifically due to abnormal ventricular heart rhythms) and reduces blood supply to the rest of the body. (wikipedia.org)
  • outcomes
  • Lower testosterone levels have been shown to be an independent risk factor for worse outcomes among men and women with heart failure. (go.com)
  • The Alliance for Heart Failure welcomed the findings but called for more to be done to address the vast regional variation in patient outcomes. (wikipedia.org)
  • dyspnea
  • Ordinary physical activity does not cause undue fatigue, palpitation (feeling heart beats), or dyspnea (shortness of breath). (inquirer.net)
  • cardiologist
  • Along with your child's heart doctor (cardiologist), you are connected with other providers, such as cardiac intensivists , newborn specialists (neonatologists), neurodevelopmental pediatricians, nurses, child life specialists , social workers and others, if their expertise is needed. (seattlechildrens.org)
  • Susan Joseph is a cardiologist in Dallas, Texas, who specializes in Advanced Heart Failure and Mechanical Circulatory Support. (washingtonexaminer.com)
  • Risk
  • Abbott, a healthcare company specializing in heart failure solutions, has developed a low-risk, easy-to-insert sensor that takes exact readings of pressure inside the chest and transmits the data to doctors. (washingtonexaminer.com)
  • acute
  • In acute decompensated heart failure, the immediate goal is to re-establish adequate perfusion and oxygen delivery to end organs. (wikipedia.org)
  • Initial therapy of acute decompensated heart failure usually includes some combination of a vasodilator such as nitroglycerin, a loop diuretic such as furosemide, and non-invasive positive pressure ventilation (NIPPV). (wikipedia.org)