• Cases without a numeric score, non-squamous cell carcinoma primary tumors, and primary squamous cell carcinoma outside the head and neck were excluded. (ajnr.org)
  • GB-263 is under development for the treatment of non-small cell lung cancer, gastric cancer, esophageal cancer, head and neck squamous cell carcinoma, metastatic colorectal cancer and other solid tumors. (pharmaceutical-technology.com)
  • Head and neck cancer (HNC) is a collective name for heterogeneous tumors located in the head and neck regions for which smoking, alcohol and human papillomavirus (HPV) are documented risk factors. (diva-portal.org)
  • Head and neck squamous cell carcinoma (HNSCC), which includes a group of heterogeneous tumors from the squamous epithelium of the oral cavity, oropharynx, larynx and hypopharynx, is the seventh most common cancer in the world [ 1 ]. (biomedcentral.com)
  • KEYNOTE-158 (ClinicalTrials.gov, NCT02628067 ) is an ongoing global, open-label, non-randomized, multi-cohort, multi-center, Phase 2 study evaluating KEYTRUDA in patients with multiple types of advanced solid tumors - including endometrial carcinoma - that have progressed on standard of care therapy. (businesswire.com)
  • Whole-body MRI is feasible for the tumor staging of patients with malignant head and neck tumors and appears to be a quick, reliable and proven alternative in general and for patients with contraindications to CT. (uni-luebeck.de)
  • range 43-80 years) with advanced malignant head and neck tumors underwent whole-body MRI in addition to routinely performed imaging investigations, including sonography, chest X-ray, CT of the head, neck and thorax and endoscopy. (uni-luebeck.de)
  • However, the term secretory carcinoma has also been used to name tumors with the microscopic appearance of MSC that are localized in the salivary glands (now termed mammary analogue secretory carcinoma), thyroid gland (now termed salivary gland-type carcinoma of the thyroid), or skin (now termed secretory carcinoma of the skin or primary cutaneous mammary analog secretory carcinoma). (wikipedia.org)
  • We observed that head and neck cancer patients who reported more depressive symptoms at their initial appointment were more likely to miss scheduled treatment appointments and were more likely to have tumors that persisted after medical treatment," Dr. Elizabeth D. Cash from the University of Louisville School of Medicine, in Kentucky, told Reuters Health by email. (medscape.com)
  • What are head and neck cancers? (cancer.gov)
  • Most head and neck cancers begin in the moist, mucus membranes lining the inside of the mouth, nose and throat. (cancer.gov)
  • These membranes are made up of squamous cells and the head and neck cancers that grow in these cells are called squamous cell carcinomas. (cancer.gov)
  • 1 In 2010, about 36,000 Americans are estimated to have been diagnosed with head and neck cancers and an estimated 7,880 were expected have died of squamous cell carcinomas. (cancer.gov)
  • Known risks for developing head and neck cancers are smoking and heavy drinking. (cancer.gov)
  • What have TCGA researchers learned about head and neck cancers? (cancer.gov)
  • Head and neck cancers associated with human papillomavirus (HPV) and tobacco-smoking are molecularly distinct. (cancer.gov)
  • Head and neck cancer is the eighth most common cancer and accounts for 3% of all cancers in men in the United States. (spandidos-publications.com)
  • Head and neck cancers are also diagnosed more often among people over age 50 than they are among younger people. (advfn.com)
  • Although head and neck cancers include multiple histologies and primary sites, squamous cell carcinomas (SCC) originating in the oropharynx, oral cavity, larynx, or hypopharynx are the most common. (ascopost.com)
  • Today, we recognize different types of head and neck cancers, primarily those that are human papillomavirus (HPV)-positive and those that are HPV-negative. (ascopost.com)
  • In this preliminary investigation, we wanted to observe the effect that over-expressing NSP 5a3a may have on cell cycle and its potential application in cancer treatment in aggressive cancers such as head and neck carcinomas. (oncotarget.com)
  • Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and one of the most common cancers overall in the United States. (medscape.com)
  • In a study of the US Medicare population, the treatment of nonmelanoma skin cancers ranked fifth among the most expensive cancers to treat in the head-and-neck region. (medscape.com)
  • This article refers to a review about head and neck squamous cell carcinoma (HNSCC), which involves about 90% of all head and neck cancers, originated from the squamous lining of the upper aero digestive tract, including the oral cavity, pharynx, larynx and sinonasal tract. (bvsalud.org)
  • more than 90% of uterine body cancers occur in the endometrium, so the actual numbers for endometrial carcinoma cases and deaths are slightly lower than these estimates). (businesswire.com)
  • Merkel cell carcinoma is a complex condition to treat, but the specialists within Moffitt Cancer Center's Cutaneous Oncology Program have extensive experience in dealing with challenging cancers. (moffitt.org)
  • Mammary secretory carcinoma (MSC), also termed secretory carcinoma of the breast, is a rare form of the breast cancers. (wikipedia.org)
  • A few gene therapy trials now target head and neck cancer, which comprises only 4% of all cancers but has a dismal prognosis in advanced stages. (medscape.com)
  • La présente étude a estimé les fréquences relatives du cancer de la cavité buccale et du pharynx chez des patients yéménites atteints de cancers enregistrés en 2007 et 2008. (who.int)
  • Head and neck cancers represent 6% of all to definite diagnosis, number of physicians malignancies diagnosed annually in Saudi involved, availability of health services and Arabia and 33% of these are of nasopharyn- referral process. (who.int)
  • Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the first and second most common types of skin cancer, respectively. (medscape.com)
  • Actinic keratosis and basal cell carcinoma are easily excised and have a very good prognosis, while cSCC has a poor prognosis, especially if it invades the lymph nodes and adjacent vital structures. (medscape.com)
  • of those, approximately 80% were basal cell carcinoma (BCC) and 20% were cSCC. (medscape.com)
  • A biopsy should be performed for any lesion suspected of being a cutaneous neoplasm to rule out basal cell carcinoma and other dermal lesions. (medscape.com)
  • The American Joint Committee on Cancer (AJCC) tumor/node/metastasis (TNM) classification, prognostic staging groups, and histologic grades for cutaneous carcinoma of the head and neck are provided below. (medscape.com)
  • Head and Neck Squamous Cell Carcinoma Study was originally published by the National Cancer Institute. (cancer.gov)
  • Cancer stem cells (CSC) drive growth, therapy resistance, and recurrence in head and neck squamous cell carcinoma (HNSCC). (nih.gov)
  • SIGNIFICANCE: Inhibiting protein elongation with SVC112 reduces tumor growth in head and neck squamous cell carcinoma and increases the effects of radiation by targeting the cancer stem cell pool. (nih.gov)
  • "Marijuana use and increased risk of squamous cell carcinoma of the head and neck" Cancer Epidemiol Biomarkers Prev . (erowid.org)
  • Although the carcinogenic properties of marijuana smoke are similar to those of tobacco, no epidemiological studies of the relationship between marijuana use and head and neck cancer have been published. (erowid.org)
  • The relationship between marijuana use and head and neck cancer was investigated by a case-control study of 173 previously untreated cases with pathologically confirmed diagnoses of squamous cell carcinoma of the head and neck and 176 cancer-free controls at Memorial Sloan-Kettering Cancer Center between 1992 and 1994. (erowid.org)
  • The associations between marijuana use and head and neck cancer were analyzed by Mantel-Haenszel methods and logistic regression models. (erowid.org)
  • Our results suggest that marijuana use may increase the risk of head and neck cancer with a strong dose-response pattern. (erowid.org)
  • Our analysis indicated that marijuana use may interact with mutagen sensitivity and other risk factors to increase the risk of head and neck cancer. (erowid.org)
  • To date, the role of insulin receptor substrate 1 (IRS-1) in tumorigenesis and metastasis of head and neck cancer has not been elucidated. (spandidos-publications.com)
  • We propose that IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9. (spandidos-publications.com)
  • Despite the advances in combining chemotherapy with surgery and radiotherapy, survival rates for patients with recurrent head and neck cancer remain poor ( 2 , 3 ). (spandidos-publications.com)
  • To date, its role in head and neck cancer has not been identified. (spandidos-publications.com)
  • Head and neck squamous cell carcinoma (HNSCC) is a type of cancer that originates in the squamous cells lining the mucous membranes of the head and neck region. (advfn.com)
  • Swelling in the neck may also signify the spread of cancer to lymph nodes. (advfn.com)
  • The Head and Neck Imaging Reporting and Data System (NI-RADS) surveillance template for head and neck cancer includes a numeric assessment of suspicion for recurrence (1-4) for the primary site and neck. (ajnr.org)
  • nonetheless, previous studies pointed out that GC may reduce the efficacy of chemotherapy on cancer cells, especially in epidermal growth factor receptor (EGFR)-targeted therapy of head and neck squamous cell carcinoma (HNSCC) remaining to be elucidated. (techscience.com)
  • The most common risk factors for development of head and neck cancer (HNC) are tobacco, alcohol,microbial factors (high-risk human papillomaviruses, hrHPVs), systemic factors (immunosuppression, micronutrient deficiency) and UV-radiation. (irb.hr)
  • Genome-wide miRNA profiling reinforces the importance of miR-9 in human papillomavirus associated oral and oropharyngeal head and neck cancer. (irb.hr)
  • DNA methylome in head and neck cancer and oral lesions. (irb.hr)
  • GB-263 is under clinical development by Genor BioPharma and currently in Phase II for Head And Neck Cancer Squamous Cell Carcinoma. (pharmaceutical-technology.com)
  • According to GlobalData, Phase II drugs for Head And Neck Cancer Squamous Cell Carcinoma have a 26% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. (pharmaceutical-technology.com)
  • In the field of head and neck cancer, we strive for the next big jump in the recurrent and/or metastatic setting, like the one we achieved with anti-PD-1 monoclonal antibodies. (ascopost.com)
  • HPV infection has been reported to correlate with several cancer types, especially squamous cell carcinomas. (biochain.com)
  • The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. (escholarship.org)
  • Additionally, they are massively investing in the oncology sector, pharmaceutical giants, cancer associations, and other organizations for the research & development associated with HNSCC therapeutics, thereby generating lucrative opportunities for the various companies participating in the Global Head and Neck Squamous Cell Carcinoma (HNSCC) Market. (marknteladvisors.com)
  • Head and neck squamous cell carcinoma (HNSCC) is the 6th most prevalent cancer, resulting in 13,000 deaths annually in the United States alone [ 1 ]. (biomedcentral.com)
  • Despite the advances in diagnostic and therapeutic techniques, the outcome and survival of patients suffering from head and neck cancer has remained poor, primarily due to late detection, and the tendency of the disease to develop loco-regional metastasis. (ucl.ac.uk)
  • Photodynamic Therapy (PDT) is a novel treatment modality for a variety of malignant tumours, including head and neck cancer. (ucl.ac.uk)
  • Because of this, a sentinel lymph node biopsy (described in Tests for Merkel Cell Carcinoma ) is a very important part of determining the stage of the cancer. (cancer.org)
  • We propose NSP 5a3a as a potential therapeutic target for site directed cancer treatment in perhaps certain head and neck carcinomas by induction of apoptosis. (oncotarget.com)
  • Merkel cell carcinoma, a rare type of skin cancer, is an aggressive and fast-growing disease that has been associated with mortality rates higher than other types of skin cancer, including melanoma," said Dr. (merck.com)
  • Merkel cell carcinoma is an aggressive and rare form of skin cancer that is often caused by a Merkel cell associated polyomavirus. (merck.com)
  • Merkel cell carcinoma is more likely to spread to other parts of the body than most types of skin cancer. (merck.com)
  • Endometrial carcinoma begins in the inner lining of the uterus, which is known as the endometrium, and is the most common type of cancer in the uterus. (businesswire.com)
  • Background: Paclitaxel has been demonstrated to have significant activity in recurrent or metastatic head and neck cancer (HNC). (ucy.ac.cy)
  • The primary objective of this phase II study was to access the complete response (CR) rate to a new innovative induction regimen in patients with locally advanced head and neck cancer (LA-HNC). (ucy.ac.cy)
  • Our skin cancer specialists are widely published in scientific journals, and their contributions are often sought when developing new evidence-based pathways and best practices for the treatment of Merkel cell carcinoma . (moffitt.org)
  • MSC has sometimes been termed secretory carcinoma without reference to its breast cancer location. (wikipedia.org)
  • Daily adaptive radiotherapy can improve salivary gland sparing and lead to fewer acute toxicities for patients with squamous cell head and neck cancer, according to results from a randomized trial presented at the American Society for Radiation Oncology (ASTRO) 2023 Annual Meeting. (medscape.com)
  • Overall, the researchers concluded that for patients with head and neck cancer, DART "may improve physician- and patient-reported acute toxicity profiles, albeit with increased resource utilization. (medscape.com)
  • Cite this: DART Can Limit Toxicities in Head, Neck Cancer - Medscape - Oct 09, 2023. (medscape.com)
  • [ 1 ] Identifying candidate precursors or enabling genes may pave the way for cancer screening, as with the ret proto-oncogene and medullary thyroid carcinoma . (medscape.com)
  • In other parts of the world, head and neck cancer is much more prevalent. (medscape.com)
  • The male-to-female ratio in head and neck cancer is 2:1. (medscape.com)
  • In head and neck cancer, the histologic progression of severity from hyperplasia, dysplasia, and carcinoma in situ to invasion provides a framework to understand the genetic progression of cancer. (medscape.com)
  • RÉSUMÉ Des études en milieu hospitalier ont révélé des fréquences relatives très élevées du cancer oropharyngé au Yémen. (who.int)
  • Head and neck cancer develops in almost 65,000 people in the United States each year. (msdmanuals.com)
  • NEW YORK (Reuters Health) - Patients with head and neck cancer who report depressive symptoms have poorer treatment responses and significantly shorter survival, compared with other patients, researchers report. (medscape.com)
  • Patients with head and neck cancer have depression rates that are among the highest of all cancer patients, and growing evidence supports the relation between depression and early mortality. (medscape.com)
  • Dr. Cash's team evaluated the association between depressive symptoms and mortality, as well as possible behavioral (interruptions of scheduled treatment) and biological (tumor response to treatment) mediators, in their study of 134 patients with head and neck cancer. (medscape.com)
  • This means that even mild symptoms of depression may interfere with head and neck cancer treatment outcomes. (medscape.com)
  • Our findings may point to the need for careful assessment of depressive symptoms among patients with head and neck cancer preparing to undergo treatment," she said. (medscape.com)
  • Dr. Cash added, "Our observations need to be replicated in a larger population, but they are intriguing because they suggest that depressive symptoms may play a unique role in the head and neck cancer survivorship that coincides with, but is not fully explained by, the activities of the tumor. (medscape.com)
  • Workers with low professional qualification are at greater risk ranked the sixth most prevalent cancer in various countries in for developing squamous cell carcinoma (SCC) of the orophar- the world1. (bvsalud.org)
  • Anaplastic carcinoma of the thyroid (ATC) generally occurs in people in iodine-deficient areas and in a setting of previous thyroid pathology (eg, preexisting goiter, follicular thyroid cancer, papillary thyroid cancer). (medscape.com)
  • Surgery is the main treatment for most Merkel cell carcinomas (MCCs). (cancer.org)
  • License Application (sBLA) seeking accelerated approval for KEYTRUDA, Merck's anti-PD-1 therapy, for the treatment of adult and pediatric patients with recurrent locally advanced or metastatic Merkel cell carcinoma (MCC). (merck.com)
  • KEYNOTE-017 represents the longest observation to date of patients with advanced Merkel cell carcinoma receiving anti-PD-1 therapy in the first-line setting, and demonstrated durable tumor control in these patients. (merck.com)
  • We look forward to working closely with the FDA throughout the review process and to bringing KEYTRUDA to patients with Merkel cell carcinoma. (merck.com)
  • There are numerous advantages to working with the Moffitt team of Merkel cell carcinoma specialists as compared to just one medical professional. (moffitt.org)
  • If you'd like to schedule an appointment with one of our Merkel cell carcinoma specialists, call 1-888-663-3488 or submit a new patient registration form online. (moffitt.org)
  • Meet the surgeons who specialize in the treatment of Merkel cell carcinoma. (moffitt.org)
  • 3 Department of Otolaryngology-Head and Neck Surgery and. (nih.gov)
  • Head and neck squamous cell carcinoma (HNSCC) is a type of tumor that originates from the squamous epithelium of the head and neck areas, including the mucous membranes of the lips, tongue, pharynx, larynx, and others ( 1 ). (frontiersin.org)
  • Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells. (bepress.com)
  • Plasma tumor necrosis factor-α and C-reactive protein as biomarker for survival in head and neck squamous cell carcinoma. (diva-portal.org)
  • Tumor TNM staging is the main basis for prognosis and treatment decision for head and neck squamous cell carcinoma (HNSCC) despite significant heterogeneity in terms of outcome among patients with the same clinical stage. (diva-portal.org)
  • Hence, we hypothesize that the immune suppressed tumor microenvironment that characterizes oral, head and neck squamous cell carcinoma (OHNSCC) can be overcome by strategies that favor anti-tumor inflammatory T cell responses and may be an ideal tumor site for immune modulation. (bmj.com)
  • KEYTRUDA monotherapy is already playing a role for the treatment of certain patients with advanced endometrial carcinoma through the tumor-agnostic MSI-H indication which received accelerated approval four years ago. (businesswire.com)
  • However, four patients were classified as having carcinoma of unknown primary, as the primary tumor was not found with any imaging modality. (uni-luebeck.de)
  • Overall, daily adaptive radiotherapy with 1-mm planning tumor volumes reduced radiation exposure and was associated with less dermatitis and improved salivary outcomes, said lead investigator David Sher, MD , chief of head and neck radiation oncology at the University of Texas Southwestern Medical Center, Dallas. (medscape.com)
  • Population differences influence human papillomavirus associated head and neck squamous cell carcinoma outcomes: a case of non-Western population. (irb.hr)
  • Additionally, there is recurrent and/or metastatic head and neck SCC (HNSCC), where all systemic therapy is palliative, regardless of HPV status, and there continues to be a great need for improvement in outcomes for all patients. (ascopost.com)
  • Benchmarking Survival Outcomes Following Surgical Management of pT3 and pT4 Cutaneous Squamous Cell Carcinoma of the Head and Neck. (melanoma.org.au)
  • pT3/4 head and neck cutaneous squamous cell carcinomas (HNcSCCs) are associated with poor outcomes, including local recurrence, metastasis and death. (melanoma.org.au)
  • Is total thyroidectomy with bilateral central neck dissection the only surgery for papillary thyroid carcinoma patients with clinically involved central nodes? (springer.com)
  • KEYTRUDA was also granted accelerated approval in September 2019, and received full approval in July 2021, in combination with LENVIMA ® (lenvatinib) for the treatment of patients with advanced endometrial carcinoma that is not MSI-H or dMMR, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation. (businesswire.com)
  • Early Surgery and Survival of Patients with Anaplastic Thyroid Carcinoma: Analysis of a Case Series Referred to a Single Institution Between 1999 and 2012. (medscape.com)
  • Successful treatment of anaplastic thyroid carcinoma with a combination of oral valproic acid, chemotherapy, radiation and surgery. (medscape.com)
  • Docetaxel (DTX) combined with cisplatin and 5-fluorouracil has been used as induction chemotherapy for head and neck squamous cell carcinoma (HNSCC). (nih.gov)
  • To construct a prognostic signature composed of DNA repair genes to effectively predict the prognosis of patients with head and neck squamous cell carcinoma (HNSCC). (frontiersin.org)
  • Here we describe the results from a phase Ib clinical trial (NCT02274155) in which 17 patients with locally advanced head and neck squamous cell carcinoma (HNSCC) received a murine anti-human OX40 agonist antibody (MEDI6469) prior to definitive surgical resection. (bepress.com)
  • Lymph node metastasis is responsible for the high morbidity of head and neck squamous cell carcinoma (HNSCC). (spandidos-publications.com)
  • The purpose of this work was to evaluate the potential of functional imaging with 18 F-FDG PET, 18 F-fluoromisonidazole PET, diffusion-weighted MRI, and dynamic contrast-enhanced MRI to provide an appropriate and reliable biologic target for dose painting in radiotherapy for head and neck squamous cell carcinoma (HNSCC). (snmjournals.org)
  • Since its introduction in the previous decade, intensity-modulated radiotherapy has been widely applied in head and neck squamous cell carcinoma (HNSCC). (snmjournals.org)
  • Advanced head and neck squamous cell carcinoma (HNSCC) is treated with radiotherapy, chemotherapy, targeted therapy or a combination of these treatments. (researchsquare.com)
  • Background: Biomarkers that facilitate the prediction of disease recurrence in head and neck squamous cell carcinoma (HNSCC) may enable physicians to personalize treatment. (uni-koeln.de)
  • Many patients suffering from head and neck squamous cell carcinoma (HNSCC) do not benefit from cetuximab added to radiotherapy. (eurekaselect.com)
  • Distant metastases arise in 20-30% of patients with squamous cell carcinoma of the head and neck (HNSCC) in the 2 years following treatment. (cipsm.de)
  • A recent increase in the number of young patients (often nonsmokers) developing head and neck squamous cell carcinoma (HNSCC) has been documented, however, there remains no clear evidence to support the significance of any single determinant. (tcd.ie)
  • This study aims to construct a new prognostic gene signature in survival prediction and risk stratification for patients with Head and neck squamous cell carcinoma (HNSCC). (biomedcentral.com)
  • The Global Head and Neck Squamous Cell Carcinoma (HNSCC) Market is projected to grow at around 9.5% CAGR during the forecast period, i.e., 2022-27. (marknteladvisors.com)
  • Optimizing the therapeutic ratio for radiation therapy (RT) in head and neck squamous cell carcinoma (HNSCC) is uniquely challenging owing to high rates of early and late toxicity involving nearby organs at risk. (biomedcentral.com)
  • Locoregional recurrence is the most common failure pattern in patients with head and neck squamous cell carcinoma (HNSCC). (ucy.ac.cy)
  • Mutations in the CDKN2A gene are found in up to one-quarter of head and neck squamous cell carcinomas (HNSCC). (medlineplus.gov)
  • Molecular characteristics may help clinicians improve the specificity of the diagnosis and treatment of head and neck squamous cell carcinomas. (cancer.gov)
  • Preoperative imaging for high-risk cutaneous squamous cell carcinoma (HRcSCC) of the head and neck lacks robust diagnosis-specific data regarding utility and lacks established guidelines regarding indications. (ahns.info)
  • ABSTRACT Nasopharyngeal carcinoma is commonly advanced at diagnosis. (who.int)
  • For lymph node metastasis assessment, the majority of studies that evaluate the utility and accuracy of head and neck imaging are in patients with mucosal SCC, not cutaneous SCC. (ahns.info)
  • Clinically involved lymph node disease (cN1a) was defined as lymph node metastases in the central neck compartment on preoperative US. (springer.com)
  • This thesis has demonstrated that, PDT and its related optical system together are able to detect, treat and reduce invasion and metastasis of head and neck carcinoma. (ucl.ac.uk)
  • Regional metastasis of head and neck cSCC may result in enlarged and palpable submandibular or cervical lymph nodes. (medscape.com)
  • CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins. (bvsalud.org)
  • In 1980, Tavaosoli and Norris renamed juvenile breast carcinoma as "secretory carcinoma of the breast" based on its characteristic microscopic appearance of having eosinophilic (i.e. red or pink) extracellular secretions when its tissues were stained with the H&E stain. (wikipedia.org)
  • Mammary secretory carcinoma is used here to distinguish it from these formerly termed secretory carcinomas. (wikipedia.org)
  • Anaplastic carcinoma of the thyroid (ATC) is the most aggressive thyroid gland malignancy. (medscape.com)
  • The aim of this study was to compare diffusion-weighted magnetic resonance imaging (DWI) with computed tomography perfusion (CTP) for preoperative detection of metastases to lymph nodes (LNs) in head and neck squamous cell carcinoma (SCC). (hindawi.com)
  • However, one can extrapolate the imaging characteristics of suspicious lymph nodes from head and neck mucosal SCC to cSCC of the head and neck. (ahns.info)
  • 8 A review of 17 studies that each compared imaging assessments of neck lymph nodes to histopathologic findings in patients with head and neck aerodigestive SCC found that CT, MRI, and US all had fairly similar sensitivities, ranging from 80-87%, with US having the highest sensitivity. (ahns.info)
  • Photodynamic therapy in head and neck carcinomas: clinical and in vitro studies. (ucl.ac.uk)
  • In this study we evaluat- ed the clinical presentation, diagnostic delay and factors affecting delay in nasopharyngeal carcinoma. (who.int)
  • Sabol I, Smahelova J, Klozar J, Mravak-Stipetic M, Gheit T, Tommasino M, Grce M, Tachezy R. Beta-HPV types in patients with head and neck pathology and in healthy subjects. (irb.hr)
  • More than 60% of patients treated surgically for pT3/4 head and neck cSCC were alive and free of disease at 5 years posttreatment. (melanoma.org.au)
  • The detection of cervical node metastases provides very important prognostic information and often helps decide the treatment of head and neck SCC. (hindawi.com)
  • Ultimately, physicians can exercise their own preferences for imaging of patients with HRcSCC in order to evaluate 1) the extent of local invasion, 2) the possibility of regional metastases to the parotid and/or neck, and 3) the presence of distant metastases. (ahns.info)
  • For the assessment of extent of local invasion, computed tomography (CT) head/neck with contrast can be performed when bone invasion is suspected while magnetic resonance imaging (MRI) head and neck with gadolinium can be performed when deep soft tissue and/or nerve invasion are suspected. (ahns.info)
  • In the head and neck region, where malignant growth often lies near critical normal tissues, intensity-modulated radiotherapy has the potential to ensure sufficient target coverage while significantly reducing toxicity. (snmjournals.org)
  • No significant differences were found in the survival from tumours largely refractive to therapy, e.g., carcinomas of the pancreas, lung and liver. (who.int)
  • Multimodality treatment for anaplastic thyroid carcinoma--treatment outcome in 75 patients. (medscape.com)
  • Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment. (medscape.com)
  • Between May 2010 and April 2012, 30 patients with head and neck SCC underwent preoperative DWI and CTP. (hindawi.com)
  • The following text outlines the definition of HRcSCC and some possible strategies for the choice of preoperative imaging for patients with HRcSCC of the head and neck. (ahns.info)
  • According to the 2015 American Thyroid Association (ATA) guidelines, total thyroidectomy with therapeutic central-compartment neck dissection (CND) is recommended for papillary thyroid carcinoma (PTC) patients with suspicious central lymph node metastasis (CLNM) on preoperative imaging [ 1 ]. (springer.com)
  • Anaplastic carcinoma of the thyroid (ATC) typically has a rapidly progressive course. (medscape.com)
  • Le retard au diagnostic a été classé en trois catégories : lié au patient, lié au professionnel et global. (who.int)
  • We look forward to sharing the latest results from KEYNOTE-158, including updated data for KEYTRUDA in certain types of MSI-H/dMMR advanced endometrial carcinoma, at the ESMO Congress in September. (businesswire.com)
  • Cohort K enrolled 79 patients with MSI-H endometrial carcinoma and Cohort D enrolled 11 patients with MSI-H endometrial carcinoma for a total of 90 pooled patients who received KEYTRUDA as monotherapy (200 mg fixed dose every three weeks). (businesswire.com)
  • p53 mutation and cyclin D1 amplification correlate with cisplatin sensitivity in xenografted human squamous cell carcinomas from head and neck. (lu.se)
  • It was found that, using a series of human oral squamous cell carcinoma cell lines, a marked decrease of tumour invasion and migration is evident after PDT this was associated with the downregulation of MMP-9, -2 and -13, uPA and VEGF. (ucl.ac.uk)
  • The tion and oral squamous cell carcinoma (OSCC) in a Brazilian variables marital status, occupation, alcoholism and smoking population. (bvsalud.org)
  • Advancing Education, Research, and Quality of Care for the Head and Neck oncology patient. (ahns.info)
  • The mission of AHNS is to advance education, research, quality of care, and equity for the head and neck oncology patient and care team. (ahns.info)
  • Neck lump and nasal obstruction were the commonest presenting symptoms. (who.int)
  • With advancements in imaging methods, several noninvasive imaging techniques have arisen, with the potential for identifying benign and metastatic LNs in head and neck SCC, thus avoiding the complications due to biopsy sampling [ 6 ]. (hindawi.com)
  • Scholars@Duke publication: Human papillomavirus type 16 infection and squamous cell carcinoma of the head and neck in never-smokers: a matched pair analysis. (duke.edu)
  • PURPOSE: Infection with human papillomavirus (HPV) type 16 has been suggested to be a risk factor for squamous cell carcinoma of the head and neck (SCCHN) and to be more commonly associated with SCCHN occurring in the oropharynx and in never-smokers. (duke.edu)