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  • guanine
  • dubious - discuss]Its structure is similar to that of the guanine nucleobase, the only difference being that nucleotides like GTP have a ribose sugar and three phosphates, with the nucleobase attached to the 1' and the triphosphate moiety attached to the 5' carbons of the ribose. (wikipedia.org)
  • gene
  • RPMI-8226R was subjected to microarray gene expression profiling, and guanosine triphosphate (GTP) level was determined with the objective of comparing these biomarkers to the same markers in patient samples from the Phase I clinical trial. (thefreedictionary.com)
  • concentrations
  • Four triphosphates, XTP, ITP, 7-methyl-GTP and 2′-O-methyl-GTP, gave 50% inhibition of both the poly(C)- and poly(U2,C)-dependent reactions at concentrations from 0.1 to 5 mM. (biochemj.org)
  • cyclohydrolase
  • Other underlying causes of tetrahydrobiopterin deficiency are: 6-Pyruvoyl tetrahydropterin synthase (PTPS) deficiency Autosomal recessive guanosine triphosphate cyclohydrolase I (GTPCH) deficiency Pterin-4alpha-carbinolamine dehydratase (PCD) deficiency Treatment of THB deficiencies consists of THB supplementation (2-20 mg/kg per day) or diet to control blood phenylalanine concentration and replacement therapy with neurotransmitters precursors (L-DOPA and 5-HTP) and supplements of folinic acid in DHPR deficiency. (wikipedia.org)
  • Other names in common use include guanosine triphosphate cyclohydrolase II, and GTP-8-formylhydrolase. (wikipedia.org)
  • form
  • Second messenger systems are complexes of regulatory (eg, G-proteins) and catalytic (eg, adenylate cyclase, phospholipase C) proteins, which are activated by NTs (first messengers) to form specific chemicals or second messengers (eg, cAMP, inositol triphosphate or IP3, diacylglycerol or DAG). (brainstrom.org)