• phenotypes
  • Individuals with IAIA or IAi have type A blood, and individuals with IBIB or IBi have type B. IAIB people have both phenotypes, because A and B express a special dominance relationship: codominance, which means that type A and B parents can have an AB child. (wikipedia.org)
  • protein
  • 6-8 The Kidd protein is a major transporter of urea across the RBC membrane and this rapid process helps maintain the osmotic stability of the cell. (rbhh.org)
  • Most blood group polymorphisms result from single nucleotide polymorphisms (SNPs) encoding amino acid substitutions in either a glycosyltransferase or extracellular domain of a red cell membrane protein. (isbtweb.org)
  • RBCs
  • Unlike group O uncrossmatched red blood cells (RBCs), group O WB contains a substantial amount of plasma, which is incompatible with the RBCs of all non-group O recipients. (readbyqxmd.com)
  • Red blood cells (RBCs), also called erythrocytes, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues-via blood flow through the circulatory system. (wikipedia.org)
  • Red blood cells are also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage). (wikipedia.org)
  • amino
  • In this case, an amino acid chain is the functional group transferred by a peptidyl transferase. (wikipedia.org)
  • Transamination, or the transfer of an amine (or NH2) group from an amino acid to a keto acid by an aminotransferase (also known as a "transaminase"), was first noted in 1930 by D. M. Needham, after observing the disappearance of glutamic acid added to pigeon breast muscle. (wikipedia.org)
  • consist
  • Vertebrate red blood cells consist mainly of hemoglobin, a complex metalloprotein containing heme groups whose iron atoms temporarily bind to oxygen molecules (O2) in the lungs or gills and release them throughout the body. (wikipedia.org)
  • glycosyl
  • Later, Yamamoto's group showed the precise glycosyl transferase set that confers the A, B and O epitopes. (wikipedia.org)
  • A transferase is any one of a class of enzymes that enact the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). (wikipedia.org)
  • molecular
  • This comprehensive report is designed to help current suppliers and potential market entrants identify and evaluate emerging opportunities in the German molecular blood banking market during the next five years, and assist industry executives in developing effective business, new product development and marketing strategies. (pitchengine.com)
  • practice
  • In 2000 the informal International Coordinating Group for Occupational Health Psychology (ICGOHP) was founded for the purpose of facilitating OHP-related research, education, and practice as well as coordinating international conference scheduling. (wikipedia.org)
  • represents
  • This selfcertifiable group reportedly represents about 80% of all IVDs on the EU market, with only the other 20% of IVDs requiring notified body intervention. (lexology.com)
  • tissues
  • ABO was a favorite system for investigating blood group and disease associations probably because it was the first system discovered and because ABH carbohydrates are expressed on many human tissues, including red cells, platelets, vascular endothelium, and epithelium. (blogspot.ca)
  • Having oxygen-carrying proteins inside specialized cells (as opposed to oxygen carriers being dissolved in body fluid) was an important step in the evolution of vertebrates as it allows for less viscous blood, higher concentrations of oxygen, and better diffusion of oxygen from the blood to the tissues. (wikipedia.org)
  • red blood cell width is on average about 25% larger than capillary diameter, and it has been hypothesized that this improves the oxygen transfer from red blood cells to tissues. (wikipedia.org)
  • Hematology
  • Two-hundred and fifty-four clinically healthy Holstein calves (1-9days old, from 30 farms) and 82 healthy Holstein cows (between 30 and 150days in milk, from 10 farms) were blood sampled once for a complete blood count evaluation, using the ADVIA 120 hematology analyzer. (readbyqxmd.com)
  • leukocyte
  • The no-reflow phenomenon has been ascribed to leukocyte plugging and blood vessel constriction in the microcirculation. (readbyqxmd.com)
  • Leukocyte reduction is the removal of white blood cells by filtration. (wikipedia.org)
  • cells
  • The resulting red blood cells do not usually express A or B antigen at the same level that would be expected on common group A1 or B red blood cells, which can help solve the problem of an apparently genetically impossible blood group. (wikipedia.org)
  • In humans, mature red blood cells are flexible and oval biconcave disks. (wikipedia.org)
  • Approximately a quarter of the cells in the human body are red blood cells. (wikipedia.org)
  • Nearly half of the blood's volume (40% to 45%) is red blood cells. (wikipedia.org)
  • Packed red blood cells (pRBC) are red blood cells that have been donated, processed, and stored in a blood bank for blood transfusion. (wikipedia.org)
  • Almost all vertebrates, including all mammals and humans, have red blood cells. (wikipedia.org)
  • Red blood cells are cells present in blood in order to transport oxygen. (wikipedia.org)
  • The color of red blood cells is due to the heme group of hemoglobin. (wikipedia.org)
  • The blood plasma alone is straw-colored, but the red blood cells change color depending on the state of the hemoglobin: when combined with oxygen the resulting oxyhemoglobin is scarlet, and when oxygen has been released the resulting deoxyhemoglobin is of a dark red burgundy color. (wikipedia.org)
  • The red blood cells of mammals are typically shaped as biconcave disks: flattened and depressed in the center, with a dumbbell-shaped cross section, and a torus-shaped rim on the edge of the disk. (wikipedia.org)
  • However, there are some exceptions concerning shape in the artiodactyl order (even-toed ungulates including cattle, deer, and their relatives), which displays a wide variety of bizarre red blood cell morphologies: small and highly ovaloid cells in llamas and camels (family Camelidae), tiny spherical cells in mouse deer (family Tragulidae), and cells which assume fusiform, lanceolate, crescentic, and irregularly polygonal and other angular forms in red deer and wapiti (family Cervidae). (wikipedia.org)
  • carries
  • Because each unit of blood given carries risks, a trigger level lower than that at 70 to 80 g/L is now usually used as it has been shown to have better patient outcomes. (wikipedia.org)
  • vessels
  • This distinctive biconcave shape optimises the flow properties of blood in the large vessels, such as maximization of laminar flow and minimization of platelet scatter, which suppresses their atherogenic activity in those large vessels. (wikipedia.org)
  • Laboratories
  • The European Commission designates EU Reference Laboratories to help assess specific devices, a category or group of devices or specific hazards related to a category or group of devices. (lexology.com)
  • This is an excellent reference book for those of us who work in the world of blood groups, whether in research or in reference laboratories. (wiley.com)
  • enzymes
  • Prior to the realization that individual enzymes were capable of such a task, it was believed that two or more enzymes enacted functional group transfers. (wikipedia.org)
  • Plasmodium
  • These include HIV, Hepatitis B, Hepatitis C, Treponema pallidum (syphilis) and, where relevant, other infections that pose a risk to the safety of the blood supply, such as Trypanosoma cruzi (Chagas disease) and Plasmodium species (malaria). (wikipedia.org)
  • patients
  • We prospectively collected data on 8,412 consecutive patients undergoing PCI for STEMI between 2005 and 2016 in the multicenter Melbourne Interventional Group registry. (readbyqxmd.com)
  • It is often difficult for standard blood banks in Korea to supply adequate amounts of blood for patients with rare phenotype. (readbyqxmd.com)
  • WB efficiently provides treatment for shock and coagulopathy, as well as platelet hemostatic function, to patients losing large volumes of blood. (readbyqxmd.com)
  • platelet
  • Leukoreduced blood products are less likely to cause HLA alloimmunization (development of antibodies against specific blood types), febrile non-hemolytic transfusion reaction, cytomegalovirus infection, and platelet-transfusion refractoriness. (wikipedia.org)
  • distribution
  • Some associations made sense, e.g., the worldwide distribution of ABO blood groups being influenced by pandemics. (blogspot.ca)
  • These disorders include dwarfism, Angelman Syndrome, and various metabolic disorders, as well as an unusual distribution of blood types. (wikipedia.org)
  • category
  • One of the topics in the latter category was whether blood groups served biological functions. (blogspot.ca)
  • For example, methylamine:L-glutamate N-methyltransferase would be the standard naming convention for the transferase methylamine-glutamate N-methyltransferase, where methylamine is the donor, L-glutamate is the acceptor, and methyltransferase is the EC category grouping. (wikipedia.org)
  • functions
  • 12 UT-B isoforms are also important in several cellular functions, including urea nitrogen salvage in the colon, nitric oxide pathway modulation in the hippocampus, and normalization of the cardiac conduction system. (rbhh.org)
  • Specifically
  • Specifically, group A, B, and AB people have demonstrated an increased incidence of thrombotic disease compared to group O individuals, presumably because ABO influences plasma levels of von Willebrand factor (vWF). (blogspot.ca)
  • The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiological cell function such as deformability and stability while traversing the circulatory system and specifically the capillary network. (wikipedia.org)
  • specific
  • In 2012, a national blood policy was in place in 70% of countries and 62% of countries had specific legislation that covers the safety and quality of blood transfusion. (wikipedia.org)
  • Donated blood is usually subjected to processing after it is collected, to make it suitable for use in specific patient populations. (wikipedia.org)
  • practices
  • The lifestyles of the two groups are similar except for farming practices, where Hutterites use industrialized farming whereas Amish do not. (wikipedia.org)
  • hemoglobin
  • The administration of a single unit of blood is the standard for hospitalized people who are not bleeding, with this treatment then followed with re-assessment and consideration of symptoms and hemoglobin concentration. (wikipedia.org)
  • known
  • Building on the successful military experience, interest has been rekindled in transfusing whole blood (WB) early in the resuscitation of traumatically injured civilians, often before their ABO group is known. (readbyqxmd.com)
  • bank
  • In developed countries, donations are usually anonymous to the recipient, but products in a blood bank are always individually traceable through the whole cycle of donation, testing, separation into components, storage, and administration to the recipient. (wikipedia.org)
  • plasma
  • vWF levels are 25% higher in non-O compared to group O individuals, but the mechanism by which ABO group determines plasma vWF levels has not been determined. (blogspot.ca)
  • most waste carbon dioxide, however, is transported back to the pulmonary capillaries of the lungs as bicarbonate (HCO3−) dissolved in the blood plasma. (wikipedia.org)