Benztropine mesylate tablets USPFenoldopam mesylate injectionInjectionTabletTyrosineAnticholinergicChemicallyAminoCumulative actionMmolAgonistMagnesiumPharmaceuticalCompoundSolubleUrinarySaltAttached to nitrogenSymptomsFunctionalPresenceDrugPatientsErgoloid mesylatesNucleophilic substitution reactionsMesilateBenztropine mesylateImatinibDihydroergocristineMethanesulfonic acidSaltsHydergineMolecular weightReactionsTabletsAlcoholProteinSide EffectsShareAgent
Benztropine mesylate tablets USP7
- Benztropine mesylate tablets USP are indicated for use as an adjunct in the therapy of all forms of parkinsonism. (nih.gov)
- BENZTROPINE MESYLATE TABLETS USP are white coloured, circular, biconvex tablets with break line on one side and "SGP" embossed on the other side. (sgpharma.com)
- BENZTROPINE MESYLATE TABLETS USP is recommended for all forms of parkinsonism including arteriosclerotic, postencephalitic, idiopathic, as well as medicine-induced extrapyramidal disorders (except tardive dyskinesia). (sgpharma.com)
- BENZTROPINE MESYLATE TABLETS USP often is helpful in patients who have become unresponsive to other agents. (sgpharma.com)
- BENZTROPINE MESYLATE TABLETS USP is a powerful anticholinergic agent which is mainly effective in relieving tremor and rigidity. (sgpharma.com)
- Because of cumulative action of BENZTROPINE MESYLATE TABLETS USP, therapy should be initiated with a low dose which is increased gradually at five or six-day intervals to the smallest amount necessary for optimal relief. (sgpharma.com)
- When BENZTROPINE MESYLATE TABLETS USP is started, do not terminate therapy with other antiparkinsonian agents abruptly. (sgpharma.com)
Fenoldopam mesylate injection3
- Corlopam (fenoldopam mesylate) Injection is a dopamine receptor agonist (vasodilator) used for in-hospital, short-term (up to 48 hours) management of severe high blood pressure ( hypertension ) when rapid, but quickly reversible, emergency reduction of blood pressure is indicated. (rxlist.com)
- Our Corlopam (fenoldopam mesylate) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
- Corlopam (fenoldopam mesylate) injection, USP is a dopamine D1-like receptor agonist . (rxlist.com)
Injection1
- Anesthetic techniques were evaluated between four experimental groups: (A) immersion in buffered MS-222 (50 mg/L), (B) immersion in buffered MS-222 (150 mg/L) (C) immersion in Propofol (65 mg/L) and (D) Propofol injection (100 mg/kg) into VCHCZ. (researchsquare.com)
Tablet2
Tyrosine1
- Imatinib mesylate is the mesylate salt of imatinib, a tyrosine kinase inhibitor with antineoplastic activity. (medkoo.com)
Anticholinergic3
- Benztropine mesylate possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism. (nih.gov)
- When benztropine mesylate is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, patients should be advised to report gastrointestinal complaints, fever or heat intolerance promptly. (nih.gov)
- Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants. (nih.gov)
Chemically1
- It is designated chemically as 3α-(Diphenylmethoxy)-1αH, 5αH-tropane methanesulfonate. (nih.gov)
Amino2
- The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate. (nih.gov)
- Quinolines substituted in any position by one or more amino groups. (lookformedical.com)
Cumulative action1
- Since benztropine mesylate has cumulative action, continued supervision is advisable. (nih.gov)
Mmol1
- A mixture of (S)-4-benzyloxy-2-hydroxybutyl methanesulfonate (the reference compound 1-1, 12.3 g, 44.8 mmol), potassium carbonate (12.3 g, 89.0 mmol) and methanol (100 mL) was stirred at room temperature for 75 minutes. (ambeed.com)
Agonist1
- In the human prostate, doxazosin mesylate antagonizes phenylephrine (alpha 1 agonist)-induced contractions, in vitro , and binds with high affinity to the alpha 1c adrenoceptor. (nih.gov)
Magnesium1
- citation needed] Ice core samples from a single spot in Antarctica were found to have tiny inclusions of magnesium methanesulfonate dodecahydrate. (wikipedia.org)
Pharmaceutical1
- When modifying the international nonproprietary name of a pharmaceutical substance containing the group or anion, the spelling used is sometimes mesilate (as in imatinib mesilate, the mesylate salt of imatinib). (wikipedia.org)
Compound3
- Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha 1 subtype of alpha adrenergic receptors. (nih.gov)
- Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine. (nih.gov)
- This lead compound was then tested and modified by the introduction of methyl and benzamide groups to give it enhanced binding properties, resulting in imatinib Gleevec received FDA approval in May 2001. (medkoo.com)
Soluble2
- Doxazosin mesylate is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (0.8% at 25°C), and very slightly soluble in acetone and methylene chloride. (nih.gov)
- Benztropine mesylate is a crystalline white powder, very soluble in water, and has a molecular weight of 403.54. (nih.gov)
Urinary4
- Doxazosin mesylate acts within 1 to 2 weeks to decrease the severity of BPH symptoms and improve urinary flow rate. (nih.gov)
- Since alpha 1 adrenoceptors are of low density in the urinary bladder (apart from the bladder neck), doxazosin mesylate should maintain bladder contractility. (nih.gov)
- Doxazosin mesylate treatment was superior to placebo in improving patient symptoms and urinary flow rate. (nih.gov)
- Urinary retention has been reported with benztropine mesylate. (nih.gov)
Salt3
- In organosulfur chemistry, a mesylate is any salt or ester of methanesulfonic acid (CH3SO3H). (wikipedia.org)
- Related: 1218779-75-9 (Apatinib mesylate salt) 811803-05-1 (Apatinib free base). (medkoo.com)
- Used (in the form of its methanesulfonate salt) as an anaesthetic for fish. (chemspider.com)
Attached to nitrogen1
- Whereas mesylates are often hydrolytically labile, mesyl groups, when attached to nitrogen, are resistant to hydrolysis. (wikipedia.org)
Symptoms1
- In all three studies, doxazosin mesylate resulted in statistically significant relief of obstructive and irritative symptoms compared to placebo. (nih.gov)
Functional3
- Mesylate esters are a group of organic compounds that share a common functional group with the general structure CH3SO2O−R, abbreviated MsO−R, where R is an organic substituent. (wikipedia.org)
- Related to mesylate is the mesyl (Ms) or methanesulfonyl (CH3SO2) functional group. (wikipedia.org)
- This functional group appears in a variety of medications, particularly cardiac (antiarrhythmic) drugs, as a sulfonamide moiety. (wikipedia.org)
Presence2
- Mesylates are generally prepared by treating an alcohol and methanesulfonyl chloride in the presence of a base, such as triethylamine. (wikipedia.org)
- From similar titrations of acetohydroxamic acid in the absence and presence of methanesulfonate (mesylate), it was determined that Mg and Ca binding to this common DFOB counter-ion is not strong enough to interfere with the DFOB titrations. (frontiersin.org)
Drug1
- The drug may cause complaints of weakness and inability to move particular muscle groups, especially in large doses. (nih.gov)
Patients3
- The efficacy of doxazosin mesylate was evaluated extensively in over 900 patients with BPH in double-blind, placebo-controlled trials. (nih.gov)
- 36 patients received a dose of 8 mg doxazosin mesylate. (nih.gov)
- Benztropine mesylate is not recommended for use in patients with tardive dyskinesia. (nih.gov)
Ergoloid mesylates1
Nucleophilic substitution reactions1
- Mesylate is considered a leaving group in nucleophilic substitution reactions. (wikipedia.org)
Mesilate1
- When modifying the international nonproprietary name of a pharmaceutical substance containing the group or anion, the spelling used is sometimes mesilate (as in imatinib mesilate, the mesylate salt of imatinib). (wikipedia.org)
Benztropine mesylate11
- Benztropine mesylate is a synthetic compound containing structural features found in atropine and diphenhydramine. (nih.gov)
- Each tablet, for oral administration, contains 0.5 mg, 1 mg or 2 mg of benztropine mesylate. (nih.gov)
- Benztropine mesylate possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism. (nih.gov)
- Hypersensitivity to benztropine mesylate tablets. (nih.gov)
- Benztropine mesylate may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle. (nih.gov)
- When benztropine mesylate is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, patients should be advised to report gastrointestinal complaints, fever or heat intolerance promptly. (nih.gov)
- Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants. (nih.gov)
- Since benztropine mesylate contains structural features of atropine, it may produce anhidrosis. (nih.gov)
- Since benztropine mesylate has cumulative action, continued supervision is advisable. (nih.gov)
- Urinary retention has been reported with benztropine mesylate. (nih.gov)
- Benztropine mesylate is not recommended for use in patients with tardive dyskinesia. (nih.gov)
Imatinib1
- Gleevec (imatinib mesylate, STI-571) is the first targeted anti-cancer agent which was developed by Norvartis and released in 2002. (justia.com)
Dihydroergocristine2
Methanesulfonic acid1
- In organosulfur chemistry, a mesylate is any salt or ester of methanesulfonic acid (CH3SO3H). (wikipedia.org)
Salts1
- In salts, the mesylate is present as the CH3SO−3 anion. (wikipedia.org)
Hydergine1
- Technical Products and Impurities: The USP grade of hydergine contains not less than 97% and not more than 103% of the alkaloid methanesulfonate mixture, calculated on the anhydrous basis, and not less than 30.3% and not more than 36.3% of the methanesulfonate salt of each of the individual alkaloids. (nih.gov)
Molecular weight1
- The empirical formula of rasagiline mesylate is (C 12 H 13 N)CH 4 SO 3 and its molecular weight is 267.34. (recallguide.org)
Reactions2
- WebNotice, though, that unlike the halogenation reactions above, conversion of an alcohol to a tosylate or mesylate proceeds with retention of configuration at the electrophilic carbon. (urlbacklinks.com)
- Adverse reactions occurring more than once in any dosing group (once if potentially important or plausibly drug-related) in the fixed-dose constant-infusion studies are presented in Table 3 . (pfizermedicalinformation.com)
Tablets1
- AZILECT® tablets contain rasagiline (as the mesylate), a propargylamine-based drug indicated for the treatment of idiopathic Parkinson's disease. (recallguide.org)
Alcohol2
- Mesylates are generally prepared by treating an alcohol and methanesulfonyl chloride in the presence of a base, such as triethylamine. (wikipedia.org)
- WebHow to convert an alcohol into a mesylate or tosylate, making it a good leaving group. (urlbacklinks.com)
Protein2
- WebImatinib mesylate is a small molecule protein tyrosine kinase inhibitor that inhibits the Bcr-Abl tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myeloid leukemia (CML). (urlbacklinks.com)
- Protein kinases are a group of enzymes for phosphorylation of hydroxyl groups in serine, threonine, and tyrosine moieties of protein. (justia.com)
Side Effects1
- WebDoxazosin MESYLATE - Uses, Side Effects, and More Common Brand (S): Cardura Uses Doxazosin is used alone or with other drugs to treat high blood pressure (hypertension). (urlbacklinks.com)
Share1
- Mesylate esters are a group of organic compounds that share a common functional group with the general structure CH3SO2O−R, abbreviated MsO−R, where R is an organic substituent. (wikipedia.org)
Agent1
- acétoxy-17-(3-pyridyl)androsta-5,16-diène), en association avec au moins un agent thérapeutique supplémentaire tel qu'un agent anticancéreux ou un stéroïde. (gc.ca)