• Dr Hussain presented Helminth Infections: A migrant health guide. (penninegplearning.co.uk)
  • More than half of the world's population is at risk of infections through parasitic worms (helminths). (swisstph.ch)
  • Many people suffer from multiple species of helminth infections. (swisstph.ch)
  • Acknowledging this contribution in 2014, the World Health Organization (WHO) has nominated Swiss TPH as a WHO Collaborating Centre for Epidemiology and Control of Helminth Infections. (swisstph.ch)
  • Helminth infections induce strong type 2 cell-mediated immune responses, characterized among other things by production of high levels of interleukin- (IL-) 4 and IL-13. (hindawi.com)
  • Such evolution may be explained by different phenomena, the most evident being that many helminths undertake specific multiorgan migratory trajectories before reaching their final destination such as the lung, intestine, liver, or blood vessels where they can persist and cause chronic infections. (hindawi.com)
  • Studies on mouse models of helminth infections have provided essential findings towards understanding type 2 immunity induction as well as its effector functions [ 12 ]. (hindawi.com)
  • Worm infections caused by soil-transmitted helminths like roundworms (Ascaris lumbricoides) pose an enormous health burden. (unibas.ch)
  • The aim is to control infections with parasitic worms that are transmitted through the soil, so-called helminths. (unibas.ch)
  • Soil-transmitted helminth infections are caused by different species of parasitic worms, including whipworms, hookworms and roundworms. (unibas.ch)
  • Whipworms are common soil-transmitted helminths that cause debilitating chronic infections in man. (nature.com)
  • Our group works on the immunology, pathogenesis, and epidemiology of helminth infections (particularly filariasis, strongyloidiasis, and hookworms), TB, and coexistent infectious diseases (helminths/ viruses and TB). (nih.gov)
  • In 2003, he was appointed as a staff scientist in the NIAID ICER program in India to continue helminth infections research work in collaboration with the Indian Council of Medical Research (ICMR). (nih.gov)
  • Since 2006, he has served as the scientific director of NIAID ICER India and works on the epidemiology and immunology of infectious diseases prevalent in India, including helminth infections, TB, HIV, and COVID-19. (nih.gov)
  • Here I applied multidisciplinary techniques to investigate the immunoepidemiology of helminth infections such as schistosomiasis and hookworm in East Africa, including how these parasitic worms may protect against asthma and allergy. (imperial.ac.uk)
  • Over 20 million preschool-age children (PSAC) in Nigeria require periodic chemotherapy (PC) for soil-transmitted helminth (STH) infections. (biomedcentral.com)
  • Persistently low coverage for this age group threatens the World Health Organization (WHO) 2030 target for eliminating STH infections. (biomedcentral.com)
  • Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study. (bvsalud.org)
  • The aim of this study was to investigate the co-occurrence of helminth infections and diabetes mellitus in adults in Lao People's Democratic Republic (Lao PDR). (bvsalud.org)
  • Stool samples for helminth diagnosis were examined with formalin - ether concentration technique for intestinal parasitic infections . (bvsalud.org)
  • This guideline provides global, evidence-informed recommendations on preventive chemotherapy (deworming), as a public health intervention in areas endemic for soil-transmitted helminths, to decrease the worm burden of soil-transmitted helminth infections in children, adolescent girls, women of reproducti. (bvsalud.org)
  • Soil-transmitted helminth (STH) infections and diarrheal illness affect billions of people yearly. (cdc.gov)
  • Food handlers plays a primary role in the transmission of pathogenically important protozoans and helminth parasites. (scielo.br)
  • This study was aimed to evaluate the prevalence of intestinal pathogenic protozoans and helminth parasites among food handlers in and around University of Malakand, Lower Dir, Pakistan. (scielo.br)
  • Seventy two cases (11.2%) of the cases presented mixed infection with both intestinal protozoan and helminth parasites. (scielo.br)
  • There are three main classes of parasites that can cause disease in humans: protozoa, helminths, and ectoparasites. (cdc.gov)
  • The Disease Ecology and Veterinary Epidemiology Shared Interest Group (SIG) brings together researchers from across the University of Glasgow that are interested in the distribution and impacts of pathogens and parasites in host populations. (gla.ac.uk)
  • Our research covers pathogens (viruses, bacteria, protozoa) and parasites (helminths, nematodes) and ranges from fundamental to applied. (gla.ac.uk)
  • Parasites - helminths live everywhere: in the earth, water, human and animal organisms. (parazitiintestinali.com)
  • Usually, helminths multiply very quickly, and the depletion of the body is a consequence of the vital activity of parasites. (parazitiintestinali.com)
  • The Parasite Genomics group uses comparative and functional genomics approaches to investigate the biology of helminths and protozoan parasites. (sanger.ac.uk)
  • Helminth parasites have a remarkable ability to persist within their mammalian hosts, which is largely due to their secretion of molecules with immunomodulatory properties. (conicet.gov.ar)
  • A year round field investigations were conducted with the aim to examine the seasonal variation in population dynamics of helminth parasites in Clarias batrachus from different natural aquatic habitat of north-eastern region of Bangladesh, Sylhet. (banglajol.info)
  • This article summarizes the percentage of prevalence, mean intensity, abundance and index of infestation of helminth parasites in the C. batrachus during different months and seasons of the year in accordance with temperature, humidity and rainfall. (banglajol.info)
  • A total 180 C. batrachus host individuals were examined and among them 139 (67.87%) specimens were found to be infested with 2205 individuals of parasites of three different groups namely trematode, cestode and nematode. (banglajol.info)
  • Amongst these parasites, soil-transmitted helminths (STHs), including Ancylostoma duodenale and Necator americanus (hookworms), Ascaris sp. (biomedcentral.com)
  • Helminths are parasites we often refer to as intestinal worms. (diabetesdaily.com)
  • The first edition of Parasitic Diseases of Wild Mammals , published in 1971, contained information on only 17 different parasites or related groups. (vin.com)
  • The parasites of homo sapiens : an annotated checklist of the protozoa, helminths and arthropods for which we are home / R. W. Ashford and W. Crewe. (who.int)
  • Parasitic helminths infect the majority of vertebrates [ 1 ]. (hindawi.com)
  • Although parasitic helminths are near to absent in northwestern countries in humans, they are still responsible for infecting more than a quarter of the human population, essentially afflicting people who live in areas of poverty in the developing world [ 2 ], and they are also heavily present in domestic animals of veterinary importance [ 3 ]. (hindawi.com)
  • Parasitic helminths generally induce strong type 2 immunity that normally controls parasite infection and is characterized by production of type 2 cytokines like interleukin- (IL-) 4, IL-5, and IL-13 by innate cells (group 2 innate lymphoid cells (ILC2s), basophils, eosinophils, neutrophils, and macrophages) and CD4 + T helper 2 (Th2) lymphocytes. (hindawi.com)
  • An important aspect about type 2 cell-mediated responses against parasitic helminths is that they are induced for controlling parasite infection but they also mediate the tolerance of parasite persistence [ 1 ]. (hindawi.com)
  • In parasitic helminths, such as hookworms, TIMPs have been proposed to play key roles in the host-parasite interplay, including invasion of and establishment in the vertebrate animal hosts. (biomedcentral.com)
  • Currently, knowledge of helminth TIMPs is limited to a small number of studies on canine hookworms, whereas no information is available on the occurrence of TIMPs in other parasitic helminths causing neglected diseases. (biomedcentral.com)
  • A total of 15 protein sequences with high homology to known eukaryotic TIMPs were predicted from the complement of sequence data available for parasitic helminths and subjected to in-depth bioinformatic analyses. (biomedcentral.com)
  • Given the limited knowledge of the molecular mechanisms linked to the development of drug resistance in parasitic helminths [ 16 ], as well as the unavailability of effective vaccines, much attention is now directed towards the identification of novel targets for intervention [ 7 , 17 ]. (biomedcentral.com)
  • A detailed understanding of the molecular biology of parasitic helminths, and in particular of the structure and function of key genes and gene products playing essential roles in host-parasite interactions, could provide a basis for the design of novel therapeutics. (biomedcentral.com)
  • To fill the anthelminthic drug pipeline, Swiss TPH researchers have now tested the drug emodepside for the first time in humans infected with soil-transmitted helminths. (unibas.ch)
  • Based on the promising results in the laboratory, we saw the potential for treating patients infected with soil-transmitted helminths," says Keiser. (unibas.ch)
  • The main messages of the guidance were to consider the possibility of helminth infection in patients who have unexplained symptoms, especially gastrointestinal symptoms or persistent unexplained eosinophilia. (penninegplearning.co.uk)
  • We can take advantage of a variety of helminth models available, each of which have their own feature including life cycle, site of infection, or pathological mechanisms influencing macrophage biology. (hindawi.com)
  • Here, we reviewed the recent advances from the laboratory mouse about macrophage origin, polarization, activation, and effector functions during parasitic helminth infection. (hindawi.com)
  • Type 2 cell-mediated immunity is a general feature of helminth infection regardless of the multivariate sites of colonization of the numerous helminth species [ 11 ] and is conserved from jawed fish to mammals [ 7 ]. (hindawi.com)
  • Effect of host selenoproteins in helminth infection. (psu.edu)
  • STH infection risk in this age group is heightened when this is coupled with low socioeconomic status, low educational status of parents, and poor WASH facilities. (biomedcentral.com)
  • METHODOLOGY/PRINCIPAL FINDINGS: An observational, cross-sectional, and analytical study was carried out comparing four groups of patients: those with concomitant diagnosis of leprosy and HIV infection without a leprosy reaction, those with leprosy and HIV co-infection patients with a reverse reaction (RR), those with leprosy without HIV and without reaction, and those with leprosywithout HIV and with RR. (bvsalud.org)
  • Ascariasis, the most common intestinal helminth infection in the world, occurs worldwide but is concentrated in tropical and subtropical areas with poor sanitation. (msdmanuals.com)
  • Persons from racial and ethnic minority groups are disproportionately affected by COVID-19, including experiencing increased risk for infection (1), hospitalization (2,3), and death (4,5). (cdc.gov)
  • The helminths identified in the influent of Tehran included Ascaris lumbricoides, hookworms, Enterobius vermicularis, Trichostrongylus spp. (who.int)
  • They are one of three major groups of soil-transmitted helminths (STHs), the others being Ascaris and hookworms, that impede the socioeconomic development of entire populations. (nature.com)
  • Season and the kind of land use favored some helminths species in this rodent, especially in the plantation area, although diversity was not largely influenced by the land use. (allenpress.com)
  • Pfam analysis revealed that although there is no universal EV marker for all helminth species, the EF-hand protein family was present in all EV datasets from cestodes and trematodes, and could serve as a platyhelminth EV biomarker. (conicet.gov.ar)
  • But truly, no group of species is a better choice for evolution's finest. (discovermagazine.com)
  • They, more than any other group out there, both exhibit extreme evolutionary adaptations and spur them onward in other species. (discovermagazine.com)
  • An updated literature survey identified 1,407 recog- these differ between the major pathogen groups or between nized species of human pathogen, 58% of which are zoonotic and nonzoonotic pathogens. (cdc.gov)
  • Each group was further divided into subgroups (families) to test whether biases existed in numbers of emerging and reemerging species at this level. (cdc.gov)
  • Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths. (bvsalud.org)
  • Before starting at Imperial I was a postdoc in Professor Anne-Marie Nybo Andersen's Perinatal, Obstetric & Paediatric Epidemiology research group at the University of Copenhagen where I held a Lundbeck Foundation fellowship to investigate the influence of early-life animal exposure on the gut microbiome and the risk of asthma. (imperial.ac.uk)
  • We investigated invasive group A Streptococcus epidemiology in Idaho, USA, during 2008-2019 using surveillance data, medical record review, and emm (M protein gene) typing results. (cdc.gov)
  • Almost (100%) prevalence of helminth infestation were recorded from both male and female C. batrachus during the winter (Nov-Jan), followed by (Feb-April) pre-monsoon (66.67-86.67%) and (Aug-Sep) post-monsoon (66.67-80.00%) while lowest (53.33-60.00%) in monsoon or rainy season (May-July). (banglajol.info)
  • Untreated entry wastewater in Tehran WTPs contained a larger variety of helminth eggs than those of Isfahan, as well as higher total egg counts. (who.int)
  • These are divided into two categories: protozoa and helminths. (spokesman.com)
  • The nature and classification of micro-organisms including bacteria, fungi, viruses, protozoa and helminths will be covered. (edu.au)
  • National Centre for Biotechnology Information, the CAB ferences between the major pathogen groups--viruses, International Bioscience database of fungal names, and bacteria, fungi, protozoa, and helminths. (cdc.gov)
  • Host Range and Emerging and Reemerging Pathogens (including microsporidia), protozoa, and helminths. (cdc.gov)
  • We examined 3 aspects of host range, both for all pathogens combined and separately for each of the virus- es, bacteria, fungi, protozoa, and helminths. (cdc.gov)
  • Soil-transmitted helminths (STHs) are a group of parasitic worms infecting both humans and animals living in resource-limited settings ( 1 ). (cdc.gov)
  • The main interest of our group is in clarifying how host and environmental factors influence the early phases of the immune response to bacteria that reside within or infect via the gastrointestinal tract. (massgeneral.org)
  • They are caused by a variety of pathogens, such as viruses, bacteria, protozoa and parasitic worms (helminths). (who.int)
  • Our group also works on the immunological and clinical outcomes of the interaction between diabetes mellitus (and other metabolic disorders) and TB, helminths (and other infectious diseases). (nih.gov)
  • Helminths are large, multicellular organisms that are generally visible to the naked eye in their adult stages. (cdc.gov)
  • In their adult form, helminths cannot multiply in humans. (cdc.gov)
  • While adult helminths do not proliferate in the intestines, they can produce eggs that are excreted in the host's feces. (spokesman.com)
  • G. lamblia is more common presence of any adult helminths. (who.int)
  • ABSTRACT To assess the type and load of helminths in wastewater and the quality of treatment, we examined the raw and treated wastewater of 8 wastewater treatment plants (WTP) in Tehran and 2 in Isfahan for the presence of helminth eggs during 2002-2003. (who.int)
  • The are a group not known to suffer from IBD and they tend to have a high number of intestinal worms. (diabetesdaily.com)
  • Helminths are multi-celled organisms that fall into three main groups: tapeworms, roundworms and thorny-headed worms. (spokesman.com)
  • Soil-transmitted helminths are highly prevalent in the Asia-Pacific region. (cdc.gov)
  • A lumbricoides is one of the soil-transmitted helminths (STH), a group that includes 16 worms. (medscape.com)
  • In this study, emodepside showed high cure rates for all three soil-transmitted helminths. (unibas.ch)
  • Overall, 442 study participants that were infected with one or more of the three main soil-transmitted helminths were enrolled. (unibas.ch)
  • Although soil-transmitted helminths (STH) are endemic in Solomon Islands, there are few recent reports on their prevalence. (who.int)
  • Soil-transmitted helminths (STH) are endemic in Pacific island countries and territories, yet there is little recent published data on country-specific prevalence. (who.int)
  • It is characteristic of flatworms including the broad groups of tapeworms and flukes. (wikipedia.org)
  • Although health aspects of guidelines in such an application are necessary, there are few data on the diversity and concentration of helminth eggs in reused wastewater in the Islamic Republic of Iran. (who.int)
  • Helminth eggs can attach to produce and can be ingested in contaminated water. (spokesman.com)
  • Despite the efforts of many research groups around the world, there is still no adequate serological test for diagnosis in endemic areas, hindering the eradication of leprosy in these regions. (bvsalud.org)
  • The group is part of the Mucosal Immunology and Biology Research Center within the Division of Pediatric Gastroenterology , and is also affiliated with the Massachusetts General Hospital Center for the Study of Inflammatory Bowel Disease. (massgeneral.org)
  • My interest in asthma and allergic disease developed during my PhD and early postdoc in Professor David Dunne's Schistosomiasis Research Group at the University of Cambridge. (imperial.ac.uk)
  • Little is known about the mutual influence of these two disease groups. (bvsalud.org)
  • Whilst several studies have begun to characterise the molecules carried by helminth EVs, work aimed at investigating their biological functions has been hindered by a lack of helminth-specific EV markers. (conicet.gov.ar)
  • Among several groups of helminth molecules involved in the host-parasite interplay, protease inhibitors have been the subject of intense investigations due to their roles in a range of fundamental molecular processes, including regulation of host proteases and modulation of the host's immune response [ 18 ]. (biomedcentral.com)
  • If I ask you what group of organisms is an exhibition of evolution at its finest, what would you say? (discovermagazine.com)
  • Although the soluble components of helminth secretions have been extensively studied, the discovery that helminths release extracellular vesicles (EVs) has added further complexity to the host-parasite interaction. (conicet.gov.ar)
  • Our analysis has identified novel markers that may be used in studies aimed at characterising helminth EVs and interrogating their function at the host-parasite interface. (conicet.gov.ar)
  • Helminths have evolved to adapt to the host they infect and developed immune evasion strategies that have in return shaped the immune system of the infected host. (hindawi.com)
  • Helminths must also ensure that their offspring will find their way out without being stopped by the host immune system [ 7 ]. (hindawi.com)
  • These often-complex life cycles have lead helminths to develop mechanisms to invade and migrate through the host while modulating the immune system and ensure their long-lasting persistence in their host [ 8 ]. (hindawi.com)
  • Few studies have been carried out concerning the structure and variation of the helminth communities of wild rodents in Brazil. (allenpress.com)
  • In another study in Thailand, groups treated with mebendazole or thiabendazole had 100% resolution of myalgias reported at 4 months. (medscape.com)
  • The exchange or transmission of health ideas, attitudes, or beliefs between individuals or groups. (bvsalud.org)
  • Results indicated that invasive group A Streptococcus is increasing among the general population of Idaho. (cdc.gov)
  • Supported by the availability of gene manipulation technologies such as RNA interference and/or transgenesis, this work provides a basis for future functional explorations of helminth TIMPs and, in particular, of their role/s in fundamental biological pathways linked to long-term establishment in the vertebrate hosts, with a view towards the development of novel approaches for the control of neglected helminthiases. (biomedcentral.com)