IMMUNOMODULATING AGENTSDrugsCytotoxicCyclophosphamideAnticancerAlkylatingAntibioticEpidermal growth fMedicinesChemotherapeutic agentsIMMUNOSUPPRESSANTSHumansComprisesInhibitorAdultChemicalNursesPharmacologyImmunosuppressiveOncologyMustardTreatmentDisease2023Chemotherapy agentsAnti-neoplasticCombinationsSearchPatientsDrugCompoundsImmuneCancerExperimental groupCellMedianTreatDiseasesClinicalVariesMetabolicControlCountries
IMMUNOMODULATING AGENTS1
- This group comprises preparations used in the treatment of neoplastic diseases, and immunomodulating agents. (whocc.no)
Drugs12
- Prepregnancy handling of antineoplastic drugs and risk of miscarriage in female nurses. (cdc.gov)
- Objective: To examine the association between handling of antineoplastic drugs (AD), use of exposure control s, and risk of miscarriage. (cdc.gov)
- In popular usage, it usually refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a standardized treatment regimen . (wikidoc.org)
- Pharmaceutical drugs / this publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans which met in Lyon, 17-24 October 1989. (who.int)
- Drugs that exert their influence during a specific phase(s) of the cell cycle are called Cell cycle -specific (CCS) drugs and include antimetabolites, some alkylating agents and vinca alkaloids. (studylib.net)
- 7. Drugs that exert their influence during any phase of the cell cycle are called Cell cycle nonspecific (CCNS) drugs and include Alkylating agents, hormones and anti-tumor antibiotics. (studylib.net)
- In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. (pharmacycode.com)
- Denileukin diftitox belongs to a group of drugs called cytotoxic proteins. (rxwiki.com)
- Hazardous drugs can include those used for cancer therapy, some antiviral drugs, hormone agents, and bioengineered drugs. (cdc.gov)
- Despite the prevention efforts to date, workplace contamination has been well documented by research on a small percentage of antineoplastic, or cancer-killing drugs. (cdc.gov)
- Some classes of drugs are more hazardous than others and, as a group, antineoplastic drugs have been shown in animal studies to be some of the most potent teratogenic agents known, at doses typically used in cancer treatment. (cdc.gov)
- Therapy-related AML (t-AML) is a subtype of AML caused by prior treatment with certain antineoplastic drugs (eg, alkylating agents, hydroxyurea , and topoisomerase II inhibitors). (msdmanuals.com)
Cytotoxic2
- DBL Cisplatin Injection belongs to a group of medicines known as antineoplastic or cytotoxic agents. (news-medical.net)
- 4. Pharmaceuticals used to destroy cancer cells are called anticancer, chemotherapeutic, antineoplastic, or cytotoxic 5. (studylib.net)
Cyclophosphamide2
- Cyclophosphamide, together with its active metabolites, aldophosphamide, acrolein and nitrogenated mustard, is an antineoplastic from the group of nitrogen mustards with very marked immunosuppressive properties. (e-lactancia.org)
- Cyclophosphamide/Alkylating Agent Concept/Action/Use Assessment Immunity CCNS Damage cell's DNA preventing reproduction of cancer cells. (studylib.net)
Anticancer3
- Anticancer agents based on natural product models / edited by John M. Cassady, John D. Douros. (who.int)
- from any individual except oneself and solar radiation, and most of the leukaemia by a genotoxic mech- or an identical twin will provoke an chemical alkylating agents used in anism after its use in anticancer immune reaction against the graft- anticancer chemotherapy. (who.int)
- The lifetime when appropriate levels of its application in anticancer chemo- Group 1 agents that act by immuno- immunosuppression are maintained. (who.int)
Alkylating15
- This is a prodrug that activates in the liver and acts as an alkylating agent. (e-lactancia.org)
- Prior therapy with alkylating agents either alone or in combination. (pocketdrugguide.com)
- Prior therapy with alkylating agents and fludarabine. (pocketdrugguide.com)
- Patients relapsed after or were refractory to alkylating agents and failed to achieve a PR with their last fludarabine-based therapy. (pocketdrugguide.com)
- Procarbazine belongs to a group of medicines called antineoplastic alkylating agents. (ourmedilife.com)
- Treosulfan is an alkylating agent that has centralized marketing authorization by the European Medicines Agency (EMA) for use in the European Union (EU) for the treatment of ovarian cancer. (affygility.com)
- Treosulfan is a bifunctional alkylating agent with antineoplastic activity derived from its nonenzymatic conversion to epoxide compounds that react with nucleophilic centers of DNA. (affygility.com)
- in contrast to busulfan, treosulfan is metabolized in vivo to active epoxides, dL-diepoxybutane, which serve as bifunctional alkylating agents. (affygility.com)
- Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. (pharmacycode.com)
- Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. (pharmacycode.com)
- Alkylating agents are cell cycle-nonspecific. (pharmacycode.com)
- Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death. (pharmacycode.com)
- ed tissues, the intensity of which and chemical alkylating agents are varies with the degree of antigenic considered to cause cancer primar- Immunosuppressive difference between graft and host. (who.int)
- An uncommon but potential y lized to act as an alkylating agent, Infection with HIV-1 is the cause of dangerous side effect of immuno- causes acute myeloid leukaemia and the acquired immune deficiency syn- suppression to support organ trans- carcinoma of the urinary bladder in drome (AIDS). (who.int)
- Most t-AMLs occur 3 to 10 years after initial therapy, with a longer latency for alkylating agents and hydroxyurea (mean latency 5 to 7 years) than for topoisomerase II inhibitors (mean latency 6 months to 3 years). (msdmanuals.com)
Antibiotic1
- Some chemotherapeutic agents with an antibiotic effect can alter the composition of the microbiota (bacterial set or bacterial flora) of the milk and the concentration of some of its components (Urbaniak 2014). (e-lactancia.org)
Epidermal growth f1
- This agent is pharmacologically classified as a human epidermal growth factor receptor type 1/epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor. (medscape.com)
Medicines1
- Vincristine belongs to the group of medicines known as antineoplastic agents. (drugs.com)
Chemotherapeutic agents2
- With succeeding generations of tumor cells, differentiation is typically lost, growth becomes less regulated, and tumors become less responsive to most chemotherapeutic agents. (wikidoc.org)
- Patients with A allele of ABCG2 had complete response to chemotherapeutic agents. (ac.ir)
IMMUNOSUPPRESSANTS3
- Immunosuppressants are defined as agents that completely or partly suppress one or more factors in the immunosystem. (whocc.no)
- This group comprises immunosuppressants excl. (whocc.no)
- Some immunosuppressants are also FDA-approved as antineoplastic agents. (medscape.com)
Humans1
- IARC Monographs act entirely or largely by immuno- heart, liver, or lung) can be trans- carcinogenic to humans (Group 1). (who.int)
Comprises1
- This group comprises antineoplastic preparations which cannot be classified in the preceding groups. (whocc.no)
Inhibitor1
- Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and colon cancer.The agent is classified as a multikinase inhibitor because ofits action on numerous kinase enzymes including thePDGF-R, VEGF-R, Kit, and Raf. (guidechem.com)
Adult1
- Methodology: A total of 28 adult BALB/c mice were randomly assigned into a control and an experimental group. (bvsalud.org)
Chemical1
- Mustard gas was used as a chemical warfare agent during World War I and was studied further during World War II. (wikidoc.org)
Nurses2
- The main goal was to investigate the potential of a probabilistic approach for exposure assessment and use this information to evaluate the impact of a complex of policy actions/interventions on dermal exposure to antineoplastic agents among oncology nurses. (bmj.com)
- The results show that the identified changes in the past decade in Dutch non-academic hospitals resulted in changes in the exposure distribution of antineoplastic agents among oncology nurses. (bmj.com)
Pharmacology3
- 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key 1 Define the following terms: 1. (studylib.net)
- 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key excretion of cellular breakdown products and to reduce the risk of hemorrhagic cystitis. (studylib.net)
- 12287987 NMNC 1230 Pharmacology Antineoplastic and Biological Response Modifiers Answer Key 3 greater, brimmed hats, and lightweight, long-sleeved shirts). (studylib.net)
Immunosuppressive1
- Risk of additive immune system effects with etrasimod has not been studied in combination with antineoplastic, immune-modulating, or noncorticosteroid immunosuppressive therapies. (medscape.com)
Oncology2
- Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma. (jamanetwork.com)
- Metastatic melanoma from intraocular primary tumors: the Southwest Oncology Group experience in phase II advanced melanoma clinical trials. (jamanetwork.com)
Mustard1
- During a military operation in World War II, a group of people were accidentally exposed to mustard gas and were later found to have very low white blood cell counts. (wikidoc.org)
Treatment6
- These agents have been shown to be beneficial in the treatment of linear IgA dermatosis. (medscape.com)
- Other uses of cytostatic chemotherapy agents (including the ones mentioned below) are the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and the suppression of transplant rejections (see immunosuppression and DMARDs ). (wikidoc.org)
- Detoxifying agents used in connection with high dose treatment of antineoplastic agents are classified in V03AF (e.g. calcium folinate). (whocc.no)
- Low strength products of ofatumumab used in the treatment of relapsing multiple sclerosis (RMS) are classified in this group, while high strength products for treatment of chronic lymphocytic leukaemia (CLL) are classified in L01FA. (whocc.no)
- p53 staining status was not associated with response to treatment in either group. (lu.se)
- Previous first-line treatment for intermediate, high, very high risk myelodysplastic syndromes (based on IPSS-R) or CMML with any antineoplastic agents including for example chemotherapy, lenalidomide and hypomethylating agents (HMAs) such as decitibine and azacitidine. (who.int)
Disease2
- Drug-induced disease may be treated merely by withdrawal of the offending agent. (medscape.com)
- These agents are used to improve the clinical and immunologic aspects of the disease. (medscape.com)
20231
- The 2023 Global Forecast for Anti-neoplastic agents, including radioactive isotopes, and specific anti-neoplastic agents (2023-2028 Outlook)-Manufacturing & Markets Report , published by Barnes Reports, contains timely and accurate market statistics and forecasts on the market for over 40 countries. (marketresearch.com)
Chemotherapy agents1
- The use of two or more chemotherapy agents is referred to as combination therapy 6. (studylib.net)
Anti-neoplastic1
- anti-neoplastic properties, which make it a potentially beneficial agent for use in cancer prevention. (natmedtalk.com)
Combinations3
- Combination products are classified in L01XY - Combinations of antineoplastic agents. (whocc.no)
- All combinations of antineoplastic agents in L01 - Antineoplastic agents are classified in this group. (whocc.no)
- Combinations of antineoplastic agents with hyaluronidase are classified at the same 5th level as the combinations of antineoplastic agents without hyaluronidase. (whocc.no)
Search1
- Spirituality and search for meaning represent pivotal coping strategies in this group, which has an excellent prognosis. (ons.org)
Patients6
- Within this group, 60% of patients achieved CR and 40% achieved PR status. (pocketdrugguide.com)
- The median survival was 35 months (median survival in the untreated group had not yet been reached versus 20 months in treated patients). (pocketdrugguide.com)
- In this randomised, controlled study patients undergoing chemotherapy were included consecutively and randomised to an experimental group receiving propolis mouthwash (n = 20) and a control group receiving diluted water (n=20). (nih.gov)
- However, it was interesting that 65% of the patients in the propolis group were completely healed at day 7 of the trial. (nih.gov)
- The severe immune plants is that suppression of the patients in whom it has been used deficiency that is characteristic of immune response can allow occult as an antineoplastic agent ( IARC, AIDS results from a deficiency in tumours or metastatic tumour cel s 2012b ). (who.int)
- Randomized pilot clinical study, with 35 patients assigned to two groups. (bvsalud.org)
Drug1
- suppression, often in concert with planted with maintenance of func- This drug has very marked immuno- other Group 1 agents, especial y tion that may continue for a normal suppressive properties. (who.int)
Compounds1
- Binds to protein and other compounds containing SH group. (medscape.com)
Immune2
- In addition, these agents modify the body's immune response to diverse stimuli. (medscape.com)
- CTCL is a group of cancers of the immune system that first appear as skin rashes. (rxwiki.com)
Cancer7
- The most active agents for pancreatic cancer have been 5-fluorouracil (5-FU) and gemcitabine. (medscape.com)
- It was reasoned that an agent that damaged the rapidly growing white blood cells might have a similar effect on cancer. (wikidoc.org)
- Oral formulations of cladribine used in multiple sclerosis are classified in this group, while parenteral formulations for cancer are classified in L01BB. (whocc.no)
- Cancer (CA): group of diseases in which abnormal cells grow out of control and can spread to other areas of the body 2. (studylib.net)
- When you join MASCC, you become eligible to join up to three study groups devoted to specific topic areas in supportive care in cancer. (mascc.org)
- la prise en charge du cancer col métastatique s'est enrichie depuis 2017 par la disponibilité des thérapies ciblées dans notre pays. (bvsalud.org)
- Cette étude avait pour objectifs de déterminer les caractéristiques épidémiologiques, cliniques et thérapeutiques des patientes prises en charge pour cancer du col métastatique dans notre structure. (bvsalud.org)
Experimental group1
- Mice in the experimental group were immunosuppressed with 2.5 mg/kg of methotrexate for three consecutive days. (bvsalud.org)
Cell3
- These agents inhibit cell growth and proliferation. (medscape.com)
- These agents alkylate DNA bases, thereby producing "cross-links" that covalently link the two DNA strands and prevent cell replication. (pocketdrugguide.com)
- Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. (lookformedical.com)
Median1
- APL is a particularly important subtype, representing 10 to 15% of all cases of AML, striking a younger age group (median age 31 years) and particular ethnicity (Hispanics). (msdmanuals.com)
Treat1
- In that sense, the first modern chemotherapeutic agent was Paul Ehrlich 's arsphenamine , an arsenic compound discovered in 1909 and used to treat syphilis . (wikidoc.org)
Diseases1
- Oral formulations of sirolimus used in organ transplantation are classified in this group, while parenteral formulations used for neoplastic diseases are classified in L01EG. (whocc.no)
Clinical1
- Evidence-based clinical practice guidelines created by the MASCC study groups. (mascc.org)
Varies1
- [ 2 ] No sex preponderance is seen for follicular lymphomas, but the incidence increases with age and varies across racial groups. (medscape.com)
Metabolic1
- These agents have anti-inflammatory properties and cause profound and varied metabolic effects. (medscape.com)
Control3
- The distribution of different genotypes between patient and control groups was only significant for ABCG2 C421A. (ac.ir)
- The case-group underwent oral hygiene control associated with the use of chamomile tea before starting the first cycle of chemotherapy, while the control group, there were no previous guidelines and prescriptions. (bvsalud.org)
- Foram quimioterapia, mientras que en el grupo de control, no había pautas ni recetas coletados dados referentes às características sociodemográficas, à neoplasia previas. (bvsalud.org)
Countries1
- The consumption of the antineoplastic agents is in some countries measured in grams. (whocc.no)