Granulomatosis granuloma respiratory tract. Medical search. Frequent questions

Objectives Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are autoimmune vasculitides associated with antineutrophil cytoplasm antibodies that target proteinase 3 (PR3) or myeloperoxidase (MPO) found within neutrophils and monocytes. (bmj.com)
Although the structure of the granulomas and multinucleated giant cells in granulomatosis with polyangiitis (GPA) is known, little is established about what drove granuloma formation and why it is infrequently found in patients with myeloperoxidase-antineutrophil cytoplasm antibodies. (bmj.com)
Granulomatosis with polyangiitis (GPA) is a condition that causes inflammation that primarily affects the respiratory tract (including the lungs and airways) and the kidneys. (medlineplus.gov)
If you or a loved one has been diagnosed with Wegener's Granulomatosis or Granulomatosis with Polyangiitis (GPA), it's important to learn as much as possible about this chronic autoimmune disease in order to better manage your symptoms and treatment plan. (articleinsider.com)
Wegener's Granulomatosis and Granulomatosis with Polyangiitis are two different names for the same disease, which is an autoimmune disorder that primarily affects the blood vessels in the lungs, kidneys, and upper respiratory tract. (articleinsider.com)
Wegener's Granulomatosis and Granulomatosis with Polyangiitis are essentially the same disease, with the latter being the more modern name for the condition. (articleinsider.com)
Granulomatosis with polyangiitis is characterized by necrotizing granulomatous inflammation, small- and medium-sized vessel vasculitis, and focal necrotizing glomerulonephritis, often with crescent formation. (merckmanuals.com)
INTRODUCTION - "Classic" granulomatosis with polyangiitis (GPA) is a form of systemic vasculitis (polyangiitis) with necrotizing granulomatous inflammation of the upper and lower respiratory tracts, systemic necrotizing vasculitis, and necrotizing glomerulonephritis [ 1,2 ]. (medilib.ir)
See "Granulomatosis with polyangiitis and microscopic polyangiitis: Clinical manifestations and diagnosis" . (medilib.ir)
See "Granulomatosis with polyangiitis and microscopic polyangiitis: Induction and maintenance therapy" . (medilib.ir)
CLINICAL FEATURES - Patients with granulomatosis with polyangiitis (GPA) typically have both upper airway and pulmonary involvement, although a minority may have just one or the other [ 1 ]. (medilib.ir)
Microscopic polyangiitis (MPA) affecting the respiratory tract is most often associated with alveolar hemorrhage [ 6,7 ]. (medilib.ir)
Wegener's Granulomatosis, also known as Granulomatosis with Polyangiitis (GPA), is a rare autoimmune ailment characterized by inflammation of blood vessels and the formation of granulomas, leading to organ damage, particularly affecting the respiratory tract and kidneys. (lagrangenews.com)
Wegener's granulomatosis also called granulomatosis with polyangiitis is a chronic, inflammatory disease of the blood vessels with small, knot-like thickening of the skin (granulomas). (healthtwentyfour.com)
Read everything you need to know about granulomatosis with polyangiitis here. (healthtwentyfour.com)
Granulomatosis with polyangiitis is a systemic disease. (healthtwentyfour.com)
Until 2011, granulomatosis with polyangiitis was known as Morbus Wegener (also known as Wegener's granulomatosis or Wegener's granulomatosis). (healthtwentyfour.com)
wegener's granulomatosis symptoms - Granulomatosis with polyangiitis can affect different organ systems. (healthtwentyfour.com)
Starting from the nose, granulomatosis with polyangiitis (Wegener's disease) can spread further into the paranasal sinuses and cause inflammation there (inflammation of the paranasal sinuses, sinusitis). (healthtwentyfour.com)
In extreme cases, granulomatosis with polyangiitis can even lead to deafness. (healthtwentyfour.com)
Throat: Hoarseness, dysphagia or a dry cough appear when the granulomatosis with polyangiitis spreads in the throat and pharynx. (healthtwentyfour.com)
Eyes: Around 50 percent of those affected suffer from eye pain, burning eyes, eye inflammation or visual disturbances (loss of vision) during the course of granulomatosis with polyangiitis (Wegener's disease). (healthtwentyfour.com)
Granulomatosis with Polyangiitis is nearly equally distributed between the sexes, with a slight male predominance. (hopkinsvasculitis.org)
Granulomatosis with Polyangiitis typically occurs in middle age, but is found in people of all ages. (hopkinsvasculitis.org)
Although it is unusual for Granulomatosis with Polyangiitis to occur in childhood, it is not unusual for a Granulomatosis with Polyangiitis patient to be in his/her 70s or even 80s at the time of diagnosis. (hopkinsvasculitis.org)
Pictured below is a chest x-ray showing bilateral lung nodules in a 27 year old Indian man with Granulomatosis with Polyangiitis. (hopkinsvasculitis.org)
Granulomatosis with Polyangiitis can affect virtually any site in the body, but it has a predisposition for certain organs. (hopkinsvasculitis.org)
The classic organs involved in Granulomatosis with Polyangiitis are the upper respiratory tract (sinuses, nose, ears, and trachea [the "windpipe"]), the lungs, and the kidneys. (hopkinsvasculitis.org)
Listed below are the organs commonly involved in Granulomatosis with Polyangiitis and the specific disease manifestation(s) in each organ. (hopkinsvasculitis.org)
An orbital pseudotumor such as those caused by Granulomatosis with Polyangiitis can cause "proptosis", or protrusion of one eye. (hopkinsvasculitis.org)
Pictured below is a computed tomography (CAT) scan of the eyes in a patient with a retro-orbital mass (a mass behind the eye) in a man with Granulomatosis with Polyangiitis. (hopkinsvasculitis.org)
This patient has Granulomatosis with Polyangiitis, but an identical lesion may occur in Relapsing Polychondritis. (hopkinsvasculitis.org)
When Granulomatosis with Polyangiitis is active, red blood cells will form a clump or "cast" (bracketed in white) within the tubules of inflamed kidneys. (hopkinsvasculitis.org)
Granulomatosis with Polyangiitis can cause many kinds of skin rashes. (hopkinsvasculitis.org)
Granulomatosis with Polyangiitis involvement of nearly all organs has been described, including the meninges (the layers of protective tissue around the brain and spinal cord), the prostate gland, and the genito-urinary tract. (hopkinsvasculitis.org)
Granulomatosis with polyangiitis (GPA, Wegener s granulomatosis) is one of the antineutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis involving various organs such as nasal septum, sinuses, upper respiratory tract, lungs, and kidneys. (bibliomed.org)
Renal involvement of Granulomatosis with Polyangiitis is characterized morphologically by extensive crescent formation (extracapillary proliferation in Bowman's space), and clinically by crescentic or rapidly progressive glomerulonephritis that causes hematuria, erythrocyte casts, and proteinuria with progressive loss of renal function. (bibliomed.org)
The diagnosis of Granulomatosis with Polyangiitis is established most securely by biopsy specimens showing the triad of vasculitis, granulomata, and large areas of necrosis (known as geographic necrosis) admitted with acute and chronic inflammatory cells. (bibliomed.org)
The diagnosis of idiopathic hypereosinophilic syndrome poses a dilemma because clinical manifestation and serum biomarkers are similar to those of eosinophilic granulomatosis with polyangiitis. (biomedcentral.com)
Only a few cases have been reported where coronavirus disease 2019 may have caused the new onset or exacerbation of eosinophilic granulomatosis with polyangiitis or idiopathic hypereosinophilic syndrome. (biomedcentral.com)
Although the patient tested negative for anti-neutrophilic cytoplasmic antibodies and skin biopsy was negative for vasculitis, eosinophilic granulomatosis with polyangiitis could not be excluded. (biomedcentral.com)
Since glucocorticoids are a standard therapy for both idiopathic hypereosinophilic syndrome and eosinophilic granulomatosis with polyangiitis, we initiated glucocorticoids following a multidisciplinary discussion. (biomedcentral.com)
Many trials include data on pooled groups of people with wegener's granulomatosis and microscopic polyangiitis. (checkorphan.org)
Wegener's Granulomatosis, also known as Granulomatosis with Polyangiitis (GPA), is an autoimmune disease that comes along with a range of symptoms, including glomerulonephritis and associated vasculitis. (drmaggieyu.com)
When your immune system goes rogue and starts attacking your own body in granulomatosis with polyangiitis (GPA), it results in inflammation similar to arthritis rheum, manifesting as a disease. (drmaggieyu.com)
This inflammation, often seen in granulomatosis with polyangiitis and arthritis, leads to granulomas (or small nodules) forming in various organs which can cause all those different symptoms we talked about earlier related to these diseases. (drmaggieyu.com)
Essentially, it's not just about the strauss syndrome, but how it triggers an inflammatory response causing multiple side effects, including arthritis, polyangiitis, granulomatosis, and associated vasculitis. (drmaggieyu.com)
Diagnosing Wegener's granulomatosis, also known as polyangiitis, can be a tricky business, given the wide range of associated vasculitis symptoms including disease manifestations like arthritis, and their variability. (drmaggieyu.com)
They'll examine for signs of systemic vasculitis, polyangiitis, arthritis and other symptoms linked to Wegener's granulomatosis, a blood disease. (drmaggieyu.com)
Granulomatosis with polyangiitis (GPA) is a chronic and systematic autoimmune condition characterized by granuloma formation and necrotizing vasculitis of small to medium-sized vessels. (ejao.org)
Granulomatosis with polyangiitis (GPA, previously called Wegener's granulomatosis) is a rare, systemic, antineutrophil cytoplasmic antibody (ANCA)-associated form of vasculitis whose lesions usually affect the respiratory tract and kidneys [ 1 ]. (ejao.org)
Manifestations are similar to granulomatosis with polyangiitis . (amboss.com)
Clinical features are very similar to those of granulomatosis with polyangiitis ( GPA ), but MPA spares the vessels in the upper respiratory tract (no sinusitis or rhinitis ). (amboss.com)
This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and GRANULOMATOSIS WITH POLYANGIITIS . (nih.gov)
Granulomatosis with polyangiitis (GPA) is a type of vasculitis associated with neutrophil anti-cytoplasm antibodies (ANCA) which may affect small and medium calibre vessels. (reumatologiaclinica.org)

Wegener granulomatosis is an autoimmune small vessel vasculitis highly associated with anti-neutrophil cytoplasmic antibodies and characterized by necrotizing granuloma of respiratory tract, disseminated vasculitis and glomerulonephritis. (issr-journals.org)
Kidneys: The kidney vessels also become inflamed in around 50 percent of those affected by granulomatosis (glomerulonephritis). (healthtwentyfour.com)
The condition impacts various demographics worldwide, commonly presenting ocular manifestations and pulmonary infiltrates in the respiratory tracts, as well as glomerulonephritis in organ systems like the kidneys. (drmaggieyu.com)
By delving deeper into Wegener's Granulomatosis, an associated vasculitis and autoimmune disease often studied in rheumatology, we can arm ourselves with knowledge about this form of glomerulonephritis and contribute to a future where this illness is less daunting. (drmaggieyu.com)
1 It is characterised by granulomatose lesions and/or necrosing vasculitis in the upper and/or lower respiratory tract, glomerulonephritis and, less often, mucocutaneous, orbital and neurological involvement, among others. (reumatologiaclinica.org)

Wegener's granulomatosis is a rare inflammation of the blood vessels ( vasculitis ) accompanied by the formation of small tissue nodules in the affected areas. (healthtwentyfour.com)
Also known as Churg-Strauss syndrome, this is another type of vasculitis that may cause granulomas to form in the lungs. (healthline.com)
Wegener's granulomatosis is a form of vasculitis that affects the lungs, kidneys and other organs. (checkorphan.org)
Wegener's Granulomatosis (GPA ), a form of systemic vasculitis , is not a battle we fight alone, but one that requires awareness and understanding. (drmaggieyu.com)
Computed tomography (CT) of the paranasal sinuses showed thickening of the mucosa and bone erosion, and high resolution CT of the thorax revealed centrolobulillar nodules and a paravertebral pseudotumour lesion ( Fig. 1 A). CT guided biopsy was performed and showed findings that could be associated with vasculitis without granulomatosis ( Fig. 1 B and C). (reumatologiaclinica.org)

Because the HLA-DPB1 gene is involved in the immune system, changes in it might be related to the autoimmune response and inflammation in the respiratory tract and kidneys characteristic of GPA. (medlineplus.gov)
Typically, the upper and lower respiratory tract and the kidneys are affected, but any organ may be. (merckmanuals.com)
If not treated aggressively, Granulomatosis with Polyangiitis's involvement of the kidneys can lead to kidney failure. (hopkinsvasculitis.org)

The "Global Wegener's Granulomatosis Treatment Market Report and Forecast 2023-2031" report has been added to ResearchAndMarkets.com's offering. (lagrangenews.com)
DUBLIN , Sept. 18, 2023 /PRNewswire/ -- The global Wegener's Granulomatosis Treatment Market is poised to witness robust growth with a Compound Annual Growth Rate (CAGR) of 5.9% during the forecast period from 2023 to 2031. (lagrangenews.com)
This growth is primarily attributed to the increasing prevalence of Wegener's Granulomatosis and heightened awareness of this rare autoimmune disease. (lagrangenews.com)
The rising prevalence of Wegener's Granulomatosis, coupled with advancements in diagnostic techniques and treatment options, is driving the demand for treatment. (lagrangenews.com)
The Wegener's Granulomatosis Treatment Market can be segmented based on various factors, including diagnosis method, drug class, route of administration, therapeutic channel, distribution channel, and region. (lagrangenews.com)
The Wegener's Granulomatosis Treatment Market has witnessed significant growth in recent years, driven by factors such as the increasing prevalence of the disease, growing awareness of rare diseases, and the demand for innovative treatment options. (lagrangenews.com)
Notably, the rise in the prevalence of Wegener's Granulomatosis is a key driver of market growth. (lagrangenews.com)
North America currently holds the largest market share in the Wegener's Granulomatosis Treatment Market, driven by factors such as a higher prevalence of the disease, a well-established healthcare infrastructure, and substantial investments in research and development. (lagrangenews.com)
Europe also plays a significant role in the Wegener's Granulomatosis Treatment Market, with countries like the UK, Germany , and France leading the way. (lagrangenews.com)
Such as symptoms, causes, diagnosis and treatment of wegener's granulomatosis. (healthtwentyfour.com)
As a rule, wegener's disease initially affects the upper respiratory tract and, in later stages, also internal organs. (healthtwentyfour.com)
Wegener's granulomatosis is part of a larger group of vasculitic syndromes, all of which feature the presence of an abnormal type of circulating antibody termed ANCAs (antineutrophil cytoplasmic antibodies) and affect small and medium-size blood vessels. (checkorphan.org)
Although Wegener's granulomatosis affects small and medium-sized vessels, it is formally classified as one of the small vessel vasculitides in the Chapel Hill system. (checkorphan.org)
Wegener's granulomatosis is usually only suspected when a patient has had unexplained symptoms for a long period of time. (checkorphan.org)
These granulomas are the main reason for the appellation of "Wegener's granulomatosis," although it is not an essential feature. (checkorphan.org)
The standard treatment for Wegener's granulomatosis is cyclophosphamide and high dose corticosteroids for remission induction and less toxic immunosuppressants like azathioprine, leflunomide, methotrexate or mycophenolate mofetil. (checkorphan.org)
A systematic review of 84 trials examined the evidence for various treatments in Wegener's granulomatosis. (checkorphan.org)

The granulomas usually occur in the lungs or airways of people with this condition, although they can occur in the eyes or other organs. (medlineplus.gov)
In the past, the term "limited" GPA was used to describe patients with clinical findings isolated to the upper respiratory tract or lungs, which occurs in approximately one-fourth of cases. (medilib.ir)
Many patients with disease limited to upper respiratory tract or lungs subsequently develop systemic involvement [ 9 ]. (medilib.ir)
According to a 2019 study , up to 36 percent of people with IBD had granulomas in their lungs or organs other than their gastrointestinal tracts. (healthline.com)
Hypereosinophilic syndrome is a rare disease presenting with idiopathic eosinophilia and multiple organ involvement, including the skin, lungs, gastrointestinal tract, heart, and nervous system. (biomedcentral.com)

This condition causes inflammation and the development of granulomas, or small nodules of tissue, which can damage organs and tissues if left untreated. (articleinsider.com)
If left untreated, granulomatosis later spreads to other organs, some of which are vital. (healthtwentyfour.com)

The term "granulomatosis" refers to the formed tissue nodules (= granulomas). (healthtwentyfour.com)
When lung tissue becomes inflamed from an infection or other cause, cells called histiocytes cluster to form nodules called granulomas. (healthline.com)
Lung granulomas, also referred to as rheumatoid or lung nodules, occur in 20 percent of people with RA, a condition that causes joint pain and inflammation. (healthline.com)

With publication in 1952 of the Armed Forces Institute of Pathology (AFIP) fascicle, Tumors of the Lower Respiratory Tract, Liebow became widely recognized as an authority on surgical lesions of the lung. (wikipedia.org)
Vasculitic lesions and disseminated granulomas occur only occasionally. (merckmanuals.com)
The pattern of swelling, inflammation, ulcers, and fissures is similar to that of the lesions occurring in the intestinal tract. (medscape.com)

Almost associating with urinary tract anomalies such as horseshoe or pelvic kidney, renal agenesis, duplication of the collecting system, or ectopic uterus. (issr-journals.org)
GPA initially presents itself as respiratory and renal symptoms. (ejao.org)

Patients may present with upper and lower respiratory tract symptoms (eg, recurrent nasal discharge or epistaxis, cough), followed by hypertension and edema, or with symptoms reflecting multiorgan involvement. (merckmanuals.com)
The major features of respiratory tract involvement in GPA and MPA will be reviewed here. (medilib.ir)
Airway and lung involvement - The most common respiratory symptoms in GPA and MPA are cough, hemoptysis (due to alveolar hemorrhage and/or tracheobronchial disease), dyspnea, and pleuritic pain. (medilib.ir)
Oral granulomas may occur without characteristic alimentary involvement (orofacial granulomatoses). (medscape.com)

Among the 3 types of granulomatosis, pulmonary granulomatosis appears most likely to have a very poor response to systemic treatment. (medicalexaminationhelp.com)

The clinical manifestations of GPA and MPA outside the respiratory tract are discussed separately. (medilib.ir)

Another characteristic feature of GPA is the formation of granulomas, which are small areas of inflammation composed of immune cells that aid in the inflammatory reaction. (medlineplus.gov)

The drug is rapidly absorbed from the gastrointestinal tract and metabolized in the liver and possibly the intestinal wall. (firedrug.com)

Chest infections in patients with underlying lung granulomatous and sarcomatous upper and middle respiratory tract diseases (GLUTEN-GVHD) significantly affect the patients themselves, and in particular, site here their chances of survival. (medicalexaminationhelp.com)

In most people with GPA, inflammation begins in the vessels of the respiratory tract, leading to nasal congestion, frequent nosebleeds, shortness of breath, or coughing. (medlineplus.gov)

Infections, inflammatory diseases, and other factors such as the following are associated with lung granulomas. (healthline.com)
Lung granulomas are associated with some common variable immunodeficiency disorders (CVID) that prevent your body from fighting infections and diseases. (healthline.com)
Because TNF- is addition to lung infections, NTM cause skin and soft tissue integral to granuloma generation and maintenance ( 5 , 6 ), infections, lymphadenitis (predominantly in young chil- patients using these agents are at increased risk for granu- lomatous infections, including activation of latent TB in- Author affiliations: Oregon Health and Sciences University, Port- fection ( 7 , 8 ). (cdc.gov)
Co-trimoxazole is used for the treatment of urinary tract infections (UTIs) caused by susceptible strains of E. coli, Proteus (indole-positive or -negative), Klebsiella, Morganella morganii, or Enterobacter. (antiinfectivemeds.com)
CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
The most common sources are urinary tract infections and the transient bacteremia caused by genitourinary procedures. (wheelessonline.com)

The severity of symptoms and signs varies considerably from asymptomatic (one-third of patients) to acute and fulminant alveolar hemorrhage with respiratory failure. (medilib.ir)

Systemic diseases such as sarcoidosis Sarcoidosis Sarcoidosis is a multisystem inflammatory disease that causes noncaseating granulomas. (lecturio.com)
It is one of the most common and longest described respiratory diseases, but remains elusive and poorly defined. (ersjournals.com)

Noncaseating granulomas are characteristic of orofacial Crohn disease. (medscape.com)

How does chest medicine help manage tuberculosis in patients with underlying lung granuloma? (medicalexaminationhelp.com)
Home - Hire Someone To Do Tuberculosis & Chest Medicine Exam - How does chest medicine help manage tuberculosis in patients with underlying lung granuloma? (medicalexaminationhelp.com)
cardiovascular LeukoplakiaHairy portion is a proper tuberculosis, medical granulomatosis consumed on the neoplasm of the logic. (lakesinclair.org)

Lung granulomas may occur with this condition that mostly affects the salivary and lacrimal glands, preventing your body from producing enough saliva and tears. (healthline.com)

Noncaseating granulomas are present in biopsy samples in a number of cases. (medscape.com)

Chest imaging is required for all patients with lower respiratory symptoms. (amboss.com)

The etiology of Wegener granulomatosis is linked to environmental and infectious triggers inciting onset of disease in genetically predisposed individuals. (issr-journals.org)

histopathology findings include fibrinoid necrosis without granulomas . (amboss.com)

If it is difficult to determine the response of a patient to chest medicine, early and aggressive care may help identify patients with lung granulomatosis. (medicalexaminationhelp.com)
Most patients with lung granulomatosis who do not receive, or do not receive, chest radiography appear to be resistant to the therapies typically recommended by the American Thoracic Society. (medicalexaminationhelp.com)
Until now, no chest radiograph has been shown to help determine the response of patients with lung granulomatosis who have underlying lung granuloma. (medicalexaminationhelp.com)
Lung Granulomas: What Do You Need to Know? (healthline.com)
The calcium deposits make these kinds of lung granulomas more easily seen on imaging tests, such as chest X-rays or CT scans . (healthline.com)
On a chest X-ray, some lung granulomas can potentially look like cancerous growths. (healthline.com)
While lung granulomas usually have no symptoms, their underlying cause may present symptoms. (healthline.com)
There are seldom symptoms associated with lung granulomas themselves. (healthline.com)
Lung granulomas with no abnormal symptoms may not need to be treated. (healthline.com)
Lung granulomas may form in response to respiratory conditions such as the following. (healthline.com)
People with leukemia may develop lung granulomas due to lymphomatoid granulmatosis, a rare condition caused by the overproduction of lymphocytes, or white blood cells. (healthline.com)

Bronchocentric granulomatosis often occurs, which is characterized by necrotizing granulomatous inflammation that destroys the walls of small bronchi and bronchioles. (radiopaedia.org)

She had a positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 5 weeks before her visit, which was detected because she was in close contact with her husband who had COVID-19. (biomedcentral.com)

UTIs associated with abnormalities of the urinary tract or neurogenic bladder), but other anti-infectives are preferred by most clinicians. (antiinfectivemeds.com)

The common underlying chronic granulomatosis may result from drug therapy, and a standardized treatment plan may require broad-range and thorough clinical assessment to address the degree of treatment helpful resources Most patients do not respond adequately to previous, more aggressive treatment regimens, and relapse may be imminent since many patients present with recurrent disease. (medicalexaminationhelp.com)

Increased dental caries and nutritional deficiencies may be related to decreased saliva production and malabsorption in the intestinal tract. (medscape.com)

As granulomas grow, they can invade surrounding areas, causing tissue damage. (medlineplus.gov)

Crohn disease is an idiopathic disorder that can involve the entire GI tract with transmural inflammation, noncaseating granulomas, and fissures. (medscape.com)

Anatomy11

Organisms8

Diseases61

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Phenomena and Processes1

Anthropology, Education, Sociology and Social Phenomena1

Information Science1

Health Care3

Polyangiitis55

Glomerulonephritis5

Vasculitis5

Kidneys3

Wegener's17

Lungs5

Organs2

Nodules3

Lesions3

Renal2

Involvement4

Pulmonary1

Manifestations1

Formation of granulomas1

Gastrointestinal1

Upper1

Vessels1

Infections6

Hemorrhage1

Diseases2

Characteristic1

Tuberculosis3

Affects1

Biopsy1

Lower respiratory1

Onset1

Findings1

Lung11

Granulomatous inflammation1

Acute1

Urinary tract1

Chronic1

Intestinal1

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Disease1