• Figure 10 shows the proportions of gonococci fully sensitive (MIC ≤ 0.03 mg/L), less sensitive (MIC 0.06 - 0.5 mg/L), relatively resistant (MIC ≥ 1 mg/L) or else penicillinase producing (PPNG) aggregated for Australia and by State or Territory. (health.gov.au)
  • Figure 5 shows the proportion of isolates fully sensitive, less sensitive or relatively resistant to the penicillins by chromosomal mechanisms (CMRNG) and the proportion of penicillinase-producing gonococci (PPNG) in different regions and as aggregated data for Australia. (health.gov.au)
  • Each month, N. gonorrhoeae isolates are collected from up to the first 25 men with gonococcal urethritis attending each of the participating sexually transmitted disease (STD) clinics at 27 sites. (cdc.gov)
  • Isolates of N gonorrhoeae from male urethritis patients attending four urological clinics in Hyogo and Osaka prefectures in Japan were collected during 2002. (bmj.com)
  • penicillinase-producing gonococci and relatively resistant isolates usually fail to respond to therapy with the penicillins. (health.gov.au)
  • The susceptibility of N. gonorrhoeae to ciprofloxacin is used to assess susceptibility to all equivalent fluoroquinolone antimicrobials. (cdc.gov)
  • Despite the MIC decrease (i.e., trend of improved cefixime susceptibility) during 2012-2013, the increase in the number of strains with Cfx-RS in 2014 underscores the potential threat of cephalosporin-resistant N. gonorrhoeae . (cdc.gov)
  • Staphylococcus aureus (penicillinase and nonpenicillinase-producing), H. influenzae, and Group A beta-hemolytic Streptococci. (nih.gov)
  • Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains). (com.bd)
  • Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains). (medeasy.health)
  • influenzae (beta-lactamase +ve and -ve strains), M.catarrhalis (most of which are beta-lactamase +ve), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by S.pneumoniae and H. influenzae (beta-lactamase +ve and -ve strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused byN.gonorrhoeae (penicillinase- and non-penicillinase-producing strains). (globelapharma.com)
  • Ceftriaxone and spectinomycin demonstrated lower MICs and so are recommended for N gonorrhoeae . (bmj.com)
  • Over the past decade, strains of N gonorrhoeae have been reported to develop high levels of resistance against several antimicrobial agents previously used for treatment of gonorrhoea. (bmj.com)
  • Her cervical smear test revealed N. gonorrhoeae as well as other bacteria. (termpapertutors.com)
  • The efficacy of cefpodoxime in treating male patients with rectal infections caused by N. gonorrhoeae has not been established. (globalrph.com)
  • TRNG, TetR N. gonorrhoeae (high-level plasmid mediated). (cdc.gov)
  • The Gonococcal Isolate Surveillance Project (GISP) was established in 1986 as a sentinel surveillance system to monitor trends in antimicrobial susceptibilities of N. gonorrhoeae strains in the United States. (cdc.gov)
  • Knowledge of local N gonorrhoeae susceptibilities to various antimicrobials is important for establishing a rational treatment strategy in each region. (bmj.com)
  • Susceptibilities of N gonorrhoeae should be monitored periodically by region. (bmj.com)
  • It is used in the treatment of infections caused by penicillinase-producing staphylococci. (medscape.com)
  • We investigated MICs of N gonorrhoeae isolated from men with urethritis in an urban area of Japan to establish a rational treatment strategy appropriate to the area. (bmj.com)
  • N eisseria gonorrhoeae remains one of the most common sexually transmitted pathogens in developing and developed countries. (bmj.com)
  • Rescreening for C trachomatis and N gonorrhoeae is recommended 3 months after treatment. (medscape.com)
  • Data do not support the use of cefpodoxime proxetil in the treatment of pharyngeal infections due to N. gonorrhoeae in men or women. (globalrph.com)
  • Uncomplicated skin and skin structure infections caused by Staphylococcus aureus (including penicillinase-producing strains) or Streptococcus pyogenes . (druglib.com)
  • with the exception of strains producing penicillinase), Streptococcus spp. (sdrugs.com)
  • Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains). (medeasy.health)
  • Gonorrhea caused by penicillinase-producing gonococci]. (nih.gov)
  • Isolates of N gonorrhoeae from male urethritis patients attending four urological clinics in Hyogo and Osaka prefectures in Japan were collected during 2002. (bmj.com)
  • The efficacy of cefpodoxime in treating male patients with rectal infections caused by N. gonorrhoeae has not been established. (druglib.com)
  • It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci. (medlibrary.org)
  • Majority of Staphylococci and some strains of gonococci, B. subtilis, E. coli, H. influenzae and few other bacteria produce penicillinase. (pharmacy180.com)
  • The gram-positive penicillinase producers elaborate large quantities of the enzyme which diffuses into the surroundings and can protect other inherently sensitive bacteria. (pharmacy180.com)
  • In gram-negative bacteria, penicillinase is found in small quantity, but is strategically located in-between the lipoprotein and peptidoglycan layers of the cell wall. (pharmacy180.com)
  • Penicillinase was the first β-lactamase to be identified: it was first isolated by Abraham and Chain in 1940 from gram-negative E. coli even before penicillin entered clinical use [1] but penicillinase production quickly spread to bacteria that previously did not produce it or only produced it rarely. (wikidoc.org)
  • Group 2 are penicillinases, cephalosporinases, or both inhibited by clavulanic acid, corresponding to the molecular classes A and D reflecting the original TEM and SHV genes. (wikidoc.org)
  • However, these proportions are not appreciably different from patients with penicillin-sensitive N. gonorrhoeae and may represent the patient population seen in public health clinics. (cdc.gov)
  • Penicillin G is the choice for penicillin-susceptible N gonorrhoeae infection. (medscape.com)
  • 3994 sterile beta lactamase i concentrate ( each vial contains 20 ml of 20, 000 levy units per ml of penicillinase that can inactivate 10, 000, 000 iu / ml of penicillin g ) media as specified in fd268 3995 sterile beta lactamase i supplement ( ready to use ) ( each vial contains 20ml solution. (chhattisgarhtenders.net)
  • TRNG, TetR N. gonorrhoeae (high-level plasmid mediated). (cdc.gov)
  • Both these appear to have acquired the penicillinase plasmid by conjugation or transduction and then propagated by selection. (pharmacy180.com)
  • Penicillinase is a specific type of β lactamase, showing specificity for penicillins , again by hydrolysing the beta-lactam ring. (wikidoc.org)
  • N. gonorrhoeae infection was diagnosed by the Aptima Combo 2 nucleic acid amplification test kit (Hologic Inc., https://www.hologic.com ). (cdc.gov)
  • Knowledge of local N gonorrhoeae susceptibilities to various antimicrobials is important for establishing a rational treatment strategy in each region. (bmj.com)
  • Penicillinase production should have no effect on norfloxacin activity. (drkruschinski.com)
  • Molecular weights of the various penicillinases tend to cluster near 50,000. (wikidoc.org)
  • N eisseria gonorrhoeae remains one of the most common sexually transmitted pathogens in developing and developed countries. (bmj.com)