• Digestion
  • Unmodified trypsin has its highest activity between 35 °C and 45 °C. After the modification, the optimal temperature is changed to the range of 50 °C to 55 °C. Other enzymes used for in-gel digestion are the endoproteases Lys-C, Glu-C, Asp-N and Lys-N. These proteases cut specifically at only one amino acid e.g. (wikipedia.org)
  • sodium
  • One study found that both salt and sour taste mechanisms detect, in different ways, the presence of sodium chloride (salt) in the mouth, however, acids are also detected and perceived as sour. (wikipedia.org)
  • compounds
  • The basic sensory function of MSG is attributed to its ability to enhance savory taste-active compounds when added in the proper concentration. (wikipedia.org)
  • proton
  • The amino acids (with acidic side chains) aspartic and glutamic acid: are they proton donors or proton acceptors? (scribd.com)
  • Proton donors and acceptors, i.e. acids and base may donate and accept protons in order to stabilize developing charges in the transition state.This typically has the effect of activating nucleophile and electrophile groups, or stabilizing leaving groups. (wikipedia.org)
  • When glutamic acid is dissolved in water, the amino group (-NH 2) may gain a proton (H+ ), and/or the carboxyl groups may lose protons, depending on the acidity of the medium. (wikipedia.org)
  • In sufficiently acidic environments, the amino group gains a proton and the molecule becomes a cation with a single positive charge, HOOC-CH(NH+ 3)-(CH 2)2-COOH. (wikipedia.org)
  • the carboxylic acid closer to the amine generally loses a proton, and the acid becomes the neutral zwitterion −OOC-CH(NH+ 3)-(CH 2)2-COOH. (wikipedia.org)
  • neutral
  • The diagram also shows that there is a point in the curve where the amino acid behaves as a 'neutral' salt. (coursehero.com)
  • However, in the solid state and mildly acid water solutions, the molecule assumes an electrically neutral zwitterion structure −OOC-CH(NH+ 3)-(CH 2)2-COOH. (wikipedia.org)
  • salts
  • The present invention relates to novel 7-acylaminocephalosporanic acid derivatives and pharmaceutically acceptable salts thereof. (patentgenius.com)
  • Accordingly, one object of the present invention, is to provide novel 7-acylaminocephalosporanic acid derivatives and pharmaceutically acceptable salts thereof, which are highly active against a number of pathogenic microorganisms and are usefulas antimicrobial agents. (patentgenius.com)
  • Another object of the present invention is to provide processes for the preparation of novel 7-acylaminocephalosporanic acid derivatives and salts thereof. (patentgenius.com)
  • crystals
  • In 1907 Japanese researcher Kikunae Ikeda of the Tokyo Imperial University identified brown crystals left behind after the evaporation of a large amount of kombu broth as glutamic acid. (wikipedia.org)
  • sequences
  • Polypeptides encoded by ART are also disclosed, as are methods for preparing ART DNA and amino acid sequences. (google.es)
  • In FAM63A, there are several amino acids that are conserved in all vertebrates for which sequences are available. (wikipedia.org)
  • Gly239 is the only amino acid that is conserved in all vertebrates, invertebrates, and plants for which sequences are available. (wikipedia.org)
  • The 25 amino acid sequence ranging from Val313 to Gly338 is the most highly conserved in all vertebrates, invertebrates, and plants for which sequences are available. (wikipedia.org)
  • thereof
  • More particularly, it relates to novel 7-acylaminocephalosporanic acid derivatives and pharmaceutically acceptable salt thereof, which have antimicrobial activity, to processes for the preparation thereof, to a pharmaceutical compositioncomprising the same, and to a method of using the same therapeutically in the treatment of infectious diseases in human being and animals. (patentgenius.com)
  • carbon
  • An organic acid in which one of the hydrogen atoms on a carbon atom has been replaced by NH 2 . (thefreedictionary.com)
  • Amino acids that have an asymmetric center at the α-carbon can exist in two forms, designated D and L, that are mirror images of each other. (scribd.com)
  • The alpha carbon of each amino acid is attached to four different chemical groups and is therefore considered to be what type of carbon atom? (scribd.com)
  • The alpha carbon of each amino acid is attached to four different chemical groups and is therefore considered to be a chiral carbon or optically active carbon.its alpha carbon has 2 hydrogens attached 27. (scribd.com)
  • This binding matrix traps the carbon dioxide generated by yeast or acid-base reactions, which causes the dough to rise. (quickanddirtytips.com)
  • somewhat
  • If you are starting to conclude that amino acids are somewhat like a jigsaw puzzle with many pieces that can be difficult to fit together into a coherent picture, then you are arriving at the same conclusion as many nutrition researchers! (whfoods.org)
  • comprises
  • The composition comprises an effective amount of the pharmaceutically active substance, glycyrrhetinic acid, in an amount effective for enhancing permeation of the active substance. (google.com.au)
  • The composition comprises an effective amount of the pharmaceutically active substance, glycyrrhetinic acid, in an amount effective for enhancing permeation of the active substance across the nasal membrane, and a basic salt of an amino acid as an adjuvant. (google.com.au)
  • conjugate
  • A buffer can be created by mixing a weak acid (HA) with its conjugate base (A). If an acid such as HCl is added to such a solution, A- can neutralize it, in the process being converted to HA. (scribd.com)
  • If a base is added, HA can neutralize it, in the process being converted to A-. Maximum buffering capacity occurs at a pH equal to the pKa but a conjugate acid/base pair can still serve as an effective buffer when the pH of a solution is what? (scribd.com)
  • form
  • Note: At pH values less than the pKa the protonated acid form (CH3-COOH) is the predominant species. (scribd.com)