• This pathway occurs in the liver, beginning with cholesterol being converted to 7a-hydroxycholesterol through the enzyme cholesterol-7-alpha-monooxygenase, after being transported into the liver cell. (smpdb.ca)
  • The first, continuing in the liver, uses the enzyme 3-oxo-5-beta-steroid-4-deydrogenase to become 7a-hydroxy-5b-cholestan-3-one. (smpdb.ca)
  • Mitochondrial health must be monitored carefully, because mi-tochondria are hardwired to the major metabolic pathways of the cell, and, due to their exceptional origin[1], are prone to cause cell death and a variety of other problems. (1library.net)
  • After that, aldo-keto reductase family 1 member C4 is used to create 3a,7a-dihydroxy-5b-cholestane. (smpdb.ca)
  • Anactive phosphorylase was found in mouse-liver homogenates (1.53 "¢moles phosphate released/mg protein/1o min). (nih.gov)
  • Type I glycogen storage diseases: disorders of the glucose - 6 -phosphatase/ glucose - 6 - phosphate transporter complexes. (nih.gov)
  • These data describe a unique type of glycogen storage disease, since the tumors possess the phosphorylase-activating enzymes, vet lack a functional dephosphophosphorvlase. (nih.gov)