• Hemodiafiltration (HDF) - Hemodiafiltration (HDF) is the state-of-the-art treatment for patients with chronic kidney disease and is the preferred modality of treatment in advanced countries worldwide. (apollohospitals.com)
  • Describe factors associated with higher risk for HEV seroconversion and development of chronic disease among liver and kidney transplant patients. (cdc.gov)
  • A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease. (nephcure.org)
  • Soluble urokinase plasminogen activator receptor (suPAR) independently predicts chronic kidney disease (CKD) incidence and progression. (nephcure.org)
  • Steroid-resistant nephrotic syndrome (SRNS) is an important cause of chronic kidney disease (CKD) in children that often progresses to end-stage renal disease (ESRD). (nephcure.org)
  • Membranoproliferative glomerulonephritis (MPGN) is an uncommon cause of chronic nephritis that occurs primarily in children and young adults. (medscape.com)
  • AIM: To estimate the lifetime benefit of a combination treatment of sodium-glucose co-transporter 2 (SGLT2) inhibitors and mineralocorticoid-receptor antagonists (MRA) in patients with type 2 diabetes and chronic kidney disease (CKD). (bvsalud.org)
  • In IgAN, the glomeruli are impaired by deposits of IgA-complexes in the kidney, which leads to the progression of chronic kidney disease, often resulting in end-stage renal disease requiring dialysis or kidney transplantation. (bvsalud.org)
  • Our team is skilled in diagnosing a wide range of kidney disorders, from chronic kidney disease to kidney stones. (ghchospitals.com)
  • I particularly specialise in looking after patients with kidney conditions at all stages of chronic kidney disease and acute kidney injury. (spirehealthcare.com)
  • I spent my first 5 years as a Consultant at the Renal Unit, King's College Hospital where I looked after a satellite unit cohort of haemodialysis patients, managed renal ward inpatients and provided a weekly consult service for patients with acute kidney injury and chronic kidney disease at the Trust's Princess Royal University Hospital campus. (bupa.co.uk)
  • My outpatient work focuses on his specialist interest of autoimmune renal disease as well as general nephrology outpatients including chronic kidney disease, diabetic nephropathy and hypertension. (bupa.co.uk)
  • In my private practice I am able to consult on all areas of adult nephrology including acute and chronic kidney disease, proteinuria, nephrological causes of non visible haematuria, hypertension, diabetic kidney disease, renovascular disease, polycystic kidney disease and glomerulonephritis including nephrotic syndrome (minimal change disease, FSGS and membranous nephropathy), lupus nephritis and ANCA vasculitis as well as queries related to haemodialysis. (bupa.co.uk)
  • As a renal specialist I am also able to offer advice to patients with early stages of chronic kidney disease and give advice on how to prevent progression to more advanced stages of the condition. (bupa.co.uk)
  • Systemic lupus erythematosus is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. (merckmanuals.com)
  • Rheumatoid Arthritis (RA) Rheumatoid arthritis is a chronic systemic autoimmune disease that primarily involves the joints. (merckmanuals.com)
  • Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. (lookformedical.com)
  • H-single and H/L-double transgenic mice displayed comparable high amounts of IgG3 cryoglobulins, but only H/L-double transgenic mice having 10-fold higher levels of IgG3 anti-IgG2a RF progressively developed chronic, lethal glomerulonephritis. (unige.ch)
  • Chronic kidney disease is a condition that occurs when the kidneys are damaged and cannot filter waste from the blood properly. (blimpt.com)
  • Is Chronic Kidney Failure Curable? (blimpt.com)
  • Chronic kidney failure is a problem that can be treated. (blimpt.com)
  • Chronic kidney failure, which can also be called chronic kidney disease, is characterized by the loss of kidney function for a period longer than 3 months. (blimpt.com)
  • But the main question is whether chronic kidney failure can be cured. (blimpt.com)
  • What Causes Chronic Kidney Failure? (blimpt.com)
  • Chronic kidney disease is a condition in which the kidneys lose their ability to filter blood properly. (blimpt.com)
  • Welcome to Medscape's InDiscussion series on chronic kidney disease . (medscape.com)
  • The kidney doctors in Ludhiana state that kidney failure can be acute (sudden onset) or chronic (gradual and progressive). (aasthakidneyhospital.com)
  • Underlying conditions such as diabetes, high blood pressure (hypertension), polycystic kidney disease, and glomerulonephritis can lead to chronic kidney disease, which may eventually progress to kidney failure. (aasthakidneyhospital.com)
  • Chronic kidney disease (CKD) is a long-term condition in Singapore that develops over time due to declining kidney function. (aareurology.sg)
  • There are five stages of chronic kidney disease based on the level of kidney function. (aareurology.sg)
  • The five stages of chronic kidney disease are identified based on a person's age, gender, and serum creatinine level. (aareurology.sg)
  • What are the common causes of Chronic Kidney Disease in Singapore? (aareurology.sg)
  • Chronic or recurrent inflammation can eventually lead to chronic kidney disease. (aareurology.sg)
  • Over time, if left untreated, these cysts can grow and impact kidney function, eventually leading to chronic kidney disease. (aareurology.sg)
  • repeated or severe kidney infections can cause scarring and damage to the kidney tissue, which may lead to chronic kidney disease for some people. (aareurology.sg)
  • Over time, it may lead to chronic kidney disease. (aareurology.sg)
  • Polycystic kidney disease can lead to chronic kidney disease. (aareurology.sg)
  • What are the symptoms of Chronic Kidney Disease? (aareurology.sg)
  • Chronic kidney disease may not cause many symptoms in the early stages as it is slow-progressing. (aareurology.sg)
  • The paper further underestimates chronic kidney disease because their endpoint was restricted to the absence of chronic dialysis or need for renal transplantation. (abdominalkey.com)
  • The Nephrology department at Apollo Hospitals, located on Bannerghatta Road in Bangalore, offers state-of-the-art facilities and provides care for patients with kidney diseases and a wide range of kidney problems. (apollohospitals.com)
  • Glomerulonephritis is a collection of glomerular diseases mediated by different immunologic pathogenic mechanisms, resulting in varied clinical presentation and therapeutic outcomes. (basicmedicalkey.com)
  • This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. (lookformedical.com)
  • Doctors and practitioners associated with ASN have special training and skill in diagnosing and treating diseases of the kidney. (vitadox.com)
  • Significant diseases and conditions treated by many ASN members include acid-base disturbances, glomerular diseases (such as glomerulonephritis or the nephrotic syndrome), tubulointerstitial kidney diseases, tubular defects, vasculitis, autoimmune disease, and the effects of toxins on the kidney. (vitadox.com)
  • One emerging treatment option for several antibody-mediated autoimmune diseases is the anti-CD38 antibody daratumumab, which depletes autoantibody-secreting plasma cells. (bmj.com)
  • Notably, aHUS may be classified as a primary condition or may occur secondary to bone marrow transplantation, the use of specific drugs, pneumococcal or viral infections, and autoimmune diseases [ 1 ]. (chikd.org)
  • a group of diseases that cause inflammation in the glomeruli, which are the small filters in the kidneys. (aareurology.sg)
  • conditions like lupus and other autoimmune diseases cause kidney inflammation. (aareurology.sg)
  • Glomerulopathies can further be classified as primary or secondary, with primary diseases directly affecting the kidneys and secondary diseases caused by another disease or process. (shiken.ai)
  • Plasma exchange or double filtration plasmapheresis for rapidly progressive glomerulonephritis, and low-density lipoprotein (LDL) apheresis or leukocytapheresis for nephritic syndrome are two major apheresis therapies for kidney diseases. (adacyte.com)
  • Although several possibilities of apheresis for kidney diseases were speculated in animal experiments or human studies, clinical applications have thus far been limited. (adacyte.com)
  • Moreover, these therapies would have a great potential for kidney diseases. (adacyte.com)
  • Further studies are needed to establish the effectiveness of apheresis in kidney diseases in more depth. (adacyte.com)
  • Here, the authors provide an overview of the most important pathogenic aspects indicating that TA can be a supportive therapy in systemic autoimmune diseases such as renal and neurological disorders. (adacyte.com)
  • Hemodialysis - Hemodialysis is the standard treatment for patients with kidney failure, and we have a well-maintained 27-station dialysis unit for this purpose. (apollohospitals.com)
  • People with ESRD who receive a kidney transplant generally live longer than people with ESRD who are on dialysis and may have a better quality of life. (wikipedia.org)
  • A kidney transplant can help restore function and is considered a better treatment compared with dialysis, said Dr Hersharan, who is also the centre's Medical Director for the adult kidney transplantation programme. (nuhsplus.edu.sg)
  • Our department specializes in hemodialysis and peritoneal dialysis, providing life-sustaining treatments for individuals with end-stage kidney disease. (ghchospitals.com)
  • My clinical research interests are focused on patients with the autoimmune renal disease and I am an established investigator for clinical studies in IgA nephropathy, primary FSGS and lupus nephritis alongside renal anaemia and dialysis studies. (bupa.co.uk)
  • Early detection and intervention can help prevent the progression of kidney disease and the need for dialysis or transplant. (blimpt.com)
  • The second patient with proteinase 3-ANCA-positive granulomatosis with polyangiitis, diffuse alveolar haemorrhage necessitating extracorporeal membrane oxygenation (ECMO) and acute kidney failure, requiring kidney replacement therapy, was weaned off ECMO, mechanical ventilation and dialysis and discharged home after daratumumab. (bmj.com)
  • For advanced kidney failure, dialysis may be necessary to remove waste products and excess fluids from the blood artificially. (aasthakidneyhospital.com)
  • In the absence of specific and effective therapy for many types of glomerulonephritis, supportive treatments for edema, hypertension, hyperlipidemia, and intravascular thrombosis play important roles in reducing the complications associated with the disease. (basicmedicalkey.com)
  • Medications may be prescribed to manage symptoms and underlying conditions contributing to kidney failure, such as hypertension, diabetes, or autoimmune disorders. (aasthakidneyhospital.com)
  • uncontrolled hypertension/high blood pressure can also damage the blood vessels in the kidneys and lead to CKD. (aareurology.sg)
  • Nephritic syndrome is less commonly used and typically refers to severe and acute presentations of glomerulonephritis with hypertension and reduced urine output. (shiken.ai)
  • Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). (wikipedia.org)
  • It was not until 17 June 1950, when a successful transplant was performed on Ruth Tucker, a 44-year-old woman with polycystic kidney disease, by Dr. Richard Lawler at Little Company of Mary Hospital in Evergreen Park, Illinois. (wikipedia.org)
  • Anti-glomerular basement membrane (anti-GBM) antibody disease is a rare autoimmune disorder in which circulating antibodies are directed against an antigen normally present in the GBM and alveolar basement membrane, specifically the alpha-3 chain of type IV collagen. (medscape.com)
  • In this article, Goodpasture disease and anti-GBM disease are used synonymously and refer to the presence of anti-GBM antibodies in tissues (eg, kidney, lungs, or both), independent of clinical manifestations. (medscape.com)
  • Goodpasture syndrome refers to clinically evident glomerulonephritis, pulmonary hemorrhage, or both in a patient with Goodpasture disease. (medscape.com)
  • Orange County Renal and Nephrology Medical Group had been providing care to all types of patients with kidney disease for over 40 years. (socalkidneyonline.org)
  • Southern California Kidney Consultants is dedicated to providing the highest quality and compassionate care for patients with kidney disease. (socalkidneyonline.org)
  • The primary outcome was a composite endpoint of doubling of serum creatinine, end-stage kidney disease or death because of kidney failure. (bvsalud.org)
  • CONCLUSIONS: Combined disease-modifying treatment with an SGLT2 inhibitor and MRA in patients with type 2 diabetes and CKD may substantially increase the number of years free from kidney failure and mortality. (bvsalud.org)
  • AIM: To identify the mediators between canagliflozin and renoprotection in patients with type 2 diabetes at a high risk of end-stage kidney disease (ESKD). (bvsalud.org)
  • Our team focuses on educating patients about kidney disease risk factors and preventive measures. (ghchospitals.com)
  • Epidemic proportions have been reached in Kidney disease due to an increase in diabetes , hypertensive disease, and obesity. (insightconferences.com)
  • It's a progressive disease that can cause deposits of uric acid in tissues in the entire body, especially in areas across the joints in addition to a decrease within the functioning of the kidneys. (llclinic.com)
  • By adopting a healthy lifestyle and adhering to medical advice, individuals can reduce the risk of kidney disease and promote optimal kidney function, safeguarding their overall health and well-being. (aasthakidneyhospital.com)
  • Phase 2/3 Study of VX 147 in Patients With APOL1-mediated Kidney Disease. (who.int)
  • The stage of kidney disease is determined using the glomerular filtration rate (GFR) , a formula that considers a person's age, gender, and serum creatinine level. (aareurology.sg)
  • Genetic factors such as APOL-L1 mutations are associated with an increased risk of FSGS and progression to end-stage kidney disease. (shiken.ai)
  • From the pathology standpoint, it is important to determine whether the membranous glomerulopathy may be due to a secondary cause such as an autoimmune disease, neoplasia, infection, or drugs. (abdominalkey.com)
  • incidence and predictors of post-transplant lymphoproliferative disease after kidney transplantation during adulthood and childhood: a registry study. (liverpool.ac.uk)
  • differences in the epidemiology of post-transplant lymphoproliferative disease (ptld) between adult and paediatric kidney transplant recipients remain unclear. (liverpool.ac.uk)
  • Pulmonary-Renal Syndrome Pulmonary-renal syndrome combines both diffuse alveolar hemorrhage (recurrent or persistent bleeding into the lungs) and glomerulonephritis (damage to the microscopic blood vessels in the kidneys. (msdmanuals.com)
  • This is because, over time, high blood sugar levels damage the small blood vessels in the kidneys, reducing their ability to function correctly. (aareurology.sg)
  • Islets prepared for transplantation into type 1 diabetes patients are exposed to compromising intrinsic and extrinsic factors that contribute to early graft failure, necessitating repeated islet infusions for clinical insulin independence. (researchgate.net)
  • Intrahepatic islet transplantation for type 1 diabetes is limited by the need for multiple infusions and poor islet viability posttransplantation. (researchgate.net)
  • We investigated the protective potential of PD-L1 on autoimmune diabetes by transgenically overexpressing PD-L1 in pancreatic β-cells in nonobese diabetic (NOD) mice. (diabetesjournals.org)
  • RESEARCH DESIGN AND METHODS -We established an insulin promoter-driven murine PD-L1 transgenic NOD mouse model to directly evaluate the protective effect of an organ-specific PD-L1 transgene against autoimmune diabetes. (diabetesjournals.org)
  • CONCLUSIONS -Our results demonstrate the protective potential of transgenic PD-L1 in autoimmune diabetes and illustrate its role in downregulating diabetogenic T-cells in NOD mice. (diabetesjournals.org)
  • [ 1 ] The clinical syndrome encompasses a spectrum ranging from mild or no renal involvement to rapidly progressive glomerulonephritis. (medscape.com)
  • Kidney stones are small, hard deposits that form in the kidneys and can cause severe pain and discomfort. (blimpt.com)
  • PKD is a genetic disorder where cysts filled with fluid form in the kidneys. (aareurology.sg)
  • However, kidney transplant recipients must remain on immunosuppressants (medications to suppress the immune system) for as long as the new kidney is working to prevent their body from rejecting it. (wikipedia.org)
  • Clinical presentations are similar for the three types of MPGN, but they manifest somewhat different mechanisms of complement activation and predisposition to recur in kidney transplants. (medscape.com)
  • Our team includes renowned specialists with extensive experience in kidney and urinary tract disorders. (ghchospitals.com)
  • Urinary tract infections are infections that occur in any part of the urinary system, including the bladder, urethra, or kidneys. (blimpt.com)
  • Blockages in the urinary tract, such as kidney stones or tumors, can impede urine flow, leading to kidney damage and potential failure. (aasthakidneyhospital.com)
  • when the urinary tract gets blocked due to enlarged prostate or kidney stones , it may cause damage to the kidney over time and develop into CKD. (aareurology.sg)
  • However, with antibodies against HEV at the fi rst annual checkup or the incidence of de novo HEV infections after transplantation by measuring liver enzyme activities and HEV RNA. (cdc.gov)
  • Due to trauma, surgery, or other medical conditions, sudden and severe kidney damage can be caused by infections, dehydration, kidney stones, drug toxicity, or reduced blood flow to the kidneys. (aasthakidneyhospital.com)
  • A urologist in Noida can diagnose kidney stones using imaging tests, such as X-rays or ultrasounds, and provide treatment options such as medication, surgery, or shockwave lithotripsy. (blimpt.com)
  • Pulmonary and/or renal manifestations can be encountered in various conditions, such as antineutrophilic cytoplasmic antibody (ANCA)-positive vasculitis and other autoimmune disorders. (medscape.com)
  • He started his private practice at Gleneagles Medical Centre and Mount Elizabeth Novena Specialist Centre in 2012, specialising in the evaluation and treatment of various kidney disorders. (kidneydoctor.sg)
  • Our dedicated team of nephrologists, urologists, and healthcare professionals is committed to providing comprehensive and advanced solutions for kidney-related disorders. (ghchospitals.com)
  • Autoimmune Disorders An autoimmune disorder is a malfunction of the body's immune system that causes the body to attack its own tissues. (msdmanuals.com)
  • In autoimmune disorders that involve the lungs, the immune system attacks and damages lung tissue. (msdmanuals.com)
  • Autoimmune disorders that affect the lungs also often affect other organs, particularly the kidneys. (msdmanuals.com)
  • Mice implanted with hybridoma secreting 6-19 IgG3 anti-IgG2a rheumatoid factor (RF) with cryoglobulin activity develop acute glomerulonephritis and cutaneous leukocytoclastic vasculitis. (unige.ch)
  • and T-cell proliferation, adoptive transfer, and islet transplantation were performed to evaluate the PD-L1 transgene-mediated immune-protective mechanisms. (diabetesjournals.org)
  • These antibodies usually damage the tiny air sacs (alveoli) and the capillaries of the lungs and the filtering apparatus of the kidneys. (msdmanuals.com)
  • A total of 808 adult patients underwent transplantation major genotypes of HEV have been recognized. (cdc.gov)
  • All adult patients for whom demics in developing countries, and genotypes 3 and 4 are a blood sample obtained on the day of transplantation was zoonotic and infect humans and several other animals in available were included in the study (n = 700, 529 kidney developing and industrialized countries ( 3 ). (cdc.gov)
  • Most people are born with two kidneys, each about the size of an adult fist. (kidneydoctor.sg)
  • A/Prof Tiong is the Surgical Director for the adult kidney transplantation programme at NUCOT. (nuhsplus.edu.sg)
  • Waste products are removed by the kidneys in the urine. (kidneydoctor.sg)
  • A kidney specialist in Delhi can diagnose CKD through blood and urine tests and provide appropriate treatment to manage the condition. (blimpt.com)
  • They use advanced diagnostic techniques, such as blood and urine tests, imaging studies, and kidney biopsies, to evaluate kidney function and identify any abnormalities. (blimpt.com)
  • Reduced urine production and changes in urine color (dark or foamy urine) may indicate kidney problems. (aasthakidneyhospital.com)
  • The initial presentation of the patient met the classical clinical triad of thrombotic microangiopathy (microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury) without preceding diarrheal illness. (chikd.org)
  • Hemolytic uremic syndrome (HUS) is a prototype of thrombotic microangiopathy (TMA) and is characterized by the clinical triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI) [ 1 ]. (chikd.org)
  • Thrombotic microangiopathy is not a rare complication of kidney transplantation and is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury with extensive thrombosis of the arterioles and capillaries. (ekjt.org)
  • Various factors can cause thrombotic microangiopathy after kidney transplantation, including surgery, warm and cold ischemia-reperfusion injury, exposure to immunosuppressants, infection, and rejection. (ekjt.org)
  • Numerous factors can lead to thrombotic microangiopathy (TMA) after kidney transplantation. (ekjt.org)
  • Look for a kidney specialist in Delhi who has a track record of successful outcomes, is highly recommended by other healthcare professionals, and has a patient-centered approach to care. (blimpt.com)
  • Dr Hersharan Kaur Sran , a Senior Consultant at the same department in NUCOT, shared that common symptoms of kidney failure include weakness, fatigue, nausea, and water retention. (nuhsplus.edu.sg)
  • This article explores the causes, symptoms, and treatment options for kidney failure. (aasthakidneyhospital.com)
  • In the early stages, kidney failure may not present noticeable symptoms. (aasthakidneyhospital.com)
  • I am a Consultant Kidney Doctor or Nephrologist at the Renal and Transplantation Unit, St George's University Hospitals NHS Foundation Trust. (bupa.co.uk)
  • A nephrologist in Delhi can evaluate the patient's suitability for a kidney transplant and provide pre- and post-transplant care to manage the patient's health. (blimpt.com)
  • The Renal Science Department is a center of excellence dedicated to offering comprehensive kidney care, from prevention and diagnosis to treatment and management. (ghchospitals.com)
  • Kidney failure is a serious condition that requires prompt diagnosis and appropriate management. (aasthakidneyhospital.com)
  • One of the earliest mentions about the possibility of a kidney transplant was by American medical researcher Simon Flexner, who declared in a reading of his paper on "Tendencies in Pathology" in the University of Chicago in 1907 that it would be possible in the then-future for diseased human organs substitution for healthy ones by surgery, including arteries, stomach, kidneys and heart. (wikipedia.org)
  • are capable of detoxifying the body owing to their antioxidant properties thereby protecting the essential organs like the liver, kidney, heart, etc. (researchwap.com)
  • This can deposit in multiple organs including the kidney. (shiken.ai)
  • The protective effects of V. amygdalina was further evident through decreased histopathological alteration of the urinary bladder, kidney and liver tissues unlike the CP and O. gratissimum treated groups. (researchwap.com)
  • If they are deemed a good candidate, they can be placed on a waiting list to receive a kidney from a deceased donor. (wikipedia.org)
  • The first successful kidney transplant was performed in 1954 by a team including Joseph Murray, the recipient's surgeon, and Hartwell Harrison, surgeon for the donor. (wikipedia.org)
  • In 1933 surgeon Yuriy Vorony from Kherson in Ukraine attempted the first human kidney transplant, using a kidney removed six hours earlier from a deceased donor to be reimplanted into the thigh. (wikipedia.org)
  • The recipient, Richard Herrick, died eight years after the transplantation due to complications with the donor kidney that were unrelated to the transplant. (wikipedia.org)
  • A kidney transplant involves a healthy donated kidney from a living or deceased donor. (nuhsplus.edu.sg)
  • Studies also show that living kidney donation does not change the life expectancy of the donor. (nuhsplus.edu.sg)
  • A kidney transplant is a surgical procedure that involves transplanting a healthy kidney from a donor into a patient with kidney failure. (blimpt.com)
  • What triggers an autoimmune disorder is not known. (msdmanuals.com)
  • Diffuse Alveolar Hemorrhage Diffuse alveolar hemorrhage is a syndrome of recurrent or persistent bleeding into the lungs, caused most often by an autoimmune disorder. (msdmanuals.com)
  • Early apheresis treatments in the anhepatic phase and over the following 4 days after transplantation produced low viral loads in 4 patients, negative viral loads in 2 patients, and increased viremia in 1 patient. (adacyte.com)