• Proteinuria
  • Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). (bioportfolio.com)
  • It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). (bioportfolio.com)
  • Laboratory tests may also reveal low levels of platelets (cells in the blood that aid in clotting), elevated lactate dehydrogenase (LDH, a chemical released from damaged cells, and which is therefore a marker of cellular damage), decreased haptoglobin (indicative of the breakdown of red blood cells), anemia (low red blood cell count)/schistocytes (damaged red blood cells), elevated creatinine (indicative of kidney dysfunction), and proteinuria (indicative of kidney injury). (wikipedia.org)
  • For example, approximately 1 in 6 patients with aHUS initially will present with proteinuria or hematuria without acute kidney failure. (wikipedia.org)
  • biopsy
  • The diagnosis of lupus nephritis depends on blood tests, urinalysis, X-rays, ultrasound scans of the kidneys, and a kidney biopsy. (wikipedia.org)
  • But since glomerular disease causes problems at the cellular level, the doctor will probably also recommend a kidney biopsy-a procedure in which a needle is used to extract small pieces of tissue for examination with different types of microscopes, each of which shows a different aspect of the tissue. (nih.gov)
  • disorders
  • Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. (wikipedia.org)
  • Nephritis is often caused by infections, and toxins, but is most commonly caused by autoimmune disorders that affect the major organs like kidneys. (wikipedia.org)
  • severe
  • Patients who survive the presenting signs and symptoms endure a chronic thrombotic and inflammatory state, which puts many of them at lifelong elevated risk of sudden blood clotting, kidney failure, other severe complications and premature death. (wikipedia.org)
  • urinalysis
  • Urinalysis provides information about kidney damage by indicating levels of protein and red blood cells in the urine. (nih.gov)
  • patients
  • Consequently, patients with SADS are now being enrolled in experimental protocols of immune ablation and hematopoietic stem-cell rescue (ie, bone marrow transplantation [BMT]) at several US institutions. (cancernetwork.com)
  • urine
  • Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. (bioportfolio.com)
  • Everyday, the two kidneys filter about 120 to 150 quarts of blood to produce about 1 to 2 quarts of urine, composed of wastes and extra fluid. (nih.gov)
  • Eventually, the urine drains from the kidneys into the bladder through larger tubes called ureters . (nih.gov)
  • As the kidneys inflame, they begin to excrete needed protein from the affected individual's body into the urine stream. (wikipedia.org)
  • bladder
  • A procedure in which a tiny piece of a body part, such as the kidney or bladder , is removed for examination under a microscope. (rightdiagnosis.com)
  • transplant
  • Kidney transplant outcomes from older deceased donors: A paired kidney analysis by the ERA-EDTA Registry. (uah.edu)
  • As the median age of deceased kidney donors rises, updated knowledge of transplant outcomes from older deceased donors in differing donor-recipient age groups is required. (uah.edu)
  • ultrasound
  • If these lab tests indicate kidney damage, the doctor may recommend ultrasound or an x-ray to see whether the shape or size of the kidneys is abnormal. (nih.gov)
  • fluid
  • In normal blood, albumin acts like a sponge, drawing extra fluid from the body into the bloodstream, where it remains until the kidneys remove it. (nih.gov)
  • Creatinine
  • Blood tests measure the levels of waste products such as creatinine and urea nitrogen to determine whether the filtering capacity of the kidneys is impaired. (nih.gov)
  • Outcomes
  • Using ERA-EDTA Registry data we determined survival outcomes of kidney allografts donated from the same older deceased donor (55-70 years), and transplanted into one recipient younger and one recipient of similar age to the donor. (uah.edu)