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  • Proteinuria
  • Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). (bioportfolio.com)
  • It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). (bioportfolio.com)
  • Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in adults and is found in 15 to 33% of kidney biopsies performed for heavy proteinuria. (endocrinologyadvisor.com)
  • Laboratory tests may also reveal low levels of platelets (cells in the blood that aid in clotting), elevated lactate dehydrogenase (LDH, a chemical released from damaged cells, and which is therefore a marker of cellular damage), decreased haptoglobin (indicative of the breakdown of red blood cells), anemia (low red blood cell count)/schistocytes (damaged red blood cells), elevated creatinine (indicative of kidney dysfunction), and proteinuria (indicative of kidney injury). (wikipedia.org)
  • For example, approximately 1 in 6 patients with aHUS initially will present with proteinuria or hematuria without acute kidney failure. (wikipedia.org)
  • systemic
  • The disease affects both children and adults and is characterized by systemic thrombotic microangiopathy (TMA), the formation of blood clots in small blood vessels throughout the body, which can lead to stroke, heart attack, kidney failure, and death. (wikipedia.org)
  • Patients with aHUS often present with an abrupt onset of systemic signs and symptoms such as acute kidney failure, hypertension (high blood pressure), myocardial infarction (heart attack), stroke, lung complications, pancreatitis (inflammation of the pancreas), liver necrosis (death of liver cells or tissue), encephalopathy (brain dysfunction), seizure, or coma. (wikipedia.org)
  • Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. (wikipedia.org)
  • disorders
  • In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone , dexamethasone , and hydrocortisone are used to suppress various allergic , inflammatory , and autoimmune disorders. (wikipedia.org)
  • Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. (wikipedia.org)
  • Nephritis is often caused by infections, and toxins, but is most commonly caused by autoimmune disorders that affect the major organs like kidneys. (wikipedia.org)
  • Outcomes
  • Kidney transplant outcomes from older deceased donors: A paired kidney analysis by the ERA-EDTA Registry. (uah.edu)
  • As the median age of deceased kidney donors rises, updated knowledge of transplant outcomes from older deceased donors in differing donor-recipient age groups is required. (uah.edu)
  • Using ERA-EDTA Registry data we determined survival outcomes of kidney allografts donated from the same older deceased donor (55-70 years), and transplanted into one recipient younger and one recipient of similar age to the donor. (uah.edu)
  • serum
  • Recently, children with early-onset MN were found to have circulating antibodies reactive with the cationic bovine serum albumin (BSA), which were found both in the blood and within immune deposits in the kidney. (endocrinologyadvisor.com)
  • normal
  • Conditions in which the KIDNEYS perform below the normal level for more than three months. (bioportfolio.com)
  • Kidney Transplantin India is being done successfully, and therefore nothing can stop you from leading a normal and healthy life as you get a new life along with the new kidney. (transplantcounsellor.com)
  • Class I is minimal mesangial glomerulonephritis which is histologically normal on light microscopy but with mesangial deposits on electron microscopy. (wikipedia.org)
  • organs
  • Failure of neurologic, cardiac, kidney, and gastrointestinal (GI) organs, as well as death, can occur unpredictably at any time, either very quickly or following prolonged symptomatic or asymptomatic disease progression. (wikipedia.org)
  • proteinuria
  • Laboratory tests may also reveal low levels of platelets (cells in the blood that aid in clotting), elevated lactate dehydrogenase (LDH, a chemical released from damaged cells, and which is therefore a marker of cellular damage), decreased haptoglobin (indicative of the breakdown of red blood cells), anemia (low red blood cell count)/schistocytes (damaged red blood cells), elevated creatinine (indicative of kidney dysfunction), and proteinuria (indicative of kidney injury). (wikipedia.org)
  • nephrology
  • Nephrologists may provide care to people without kidney problems and may work in general/internal medicine , transplant medicine , immunosuppression management , intensive care medicine , clinical pharmacology , perioperative medicine , or pediatric nephrology. (wikipedia.org)
  • immune
  • Stamatiades et al determined that in PSGN and other type III hypersensitivity reactions, vascular endothelial cells in the kidney actively transport circulating immune complexes from the capillaries to the peritubular interstitial space, where they are detected and scavenged by resident macrophages. (medscape.com)
  • urine
  • The donated kidney will be connected to your arteries, veins, and ureter, which is the tube that carries the urine to the bladder. (medicalcityplano.com)
  • The new kidney may start producing urine right away or within a short time. (medicalcityplano.com)
  • As the kidneys inflame, they begin to excrete needed protein from the affected individual's body into the urine stream. (wikipedia.org)
  • diagnosis
  • Evaluation of classical and novel autoantibodies for the diagnosis of Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome (PBC-AIH OS). (amedeo.com)