AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
Maternal AgeGestational AgeInfant, Small for Gestational AgePregnancyInfant, NewbornBirth WeightInfant, PrematurePregnancy OutcomeUltrasonography, PrenatalDown SyndromePremature BirthBirth OrderInfant, Low Birth WeightPaternal AgePregnancy, High-RiskPregnancy ComplicationsPregnancy Trimester, FirstPregnancy Trimester, SecondParityCrown-Rump LengthAmniocentesisFetal Growth RetardationPrenatal DiagnosisInfant, Premature, DiseasesPregnancy Trimester, ThirdInfant MortalityObstetric Labor, PrematureFetal DeathCongenital AbnormalitiesFetusRisk FactorsBirth CertificatesFetal DiseasesFetal DevelopmentCesarean SectionAbortion, SpontaneousInfant, Very Low Birth WeightTwinsStillbirthTrisomyTerm BirthPregnancy, MultipleDelivery, ObstetricApgar ScoreAmniotic FluidPrenatal CareCohort StudiesPre-EclampsiaProspective StudiesNuchal Translucency MeasurementIntensive Care Units, NeonatalMothersRetrospective StudiesPerinatal MortalityChromosome DisordersNondisjunction, GeneticAneuploidyFetal MacrosomiaChild DevelopmentChorionic Gonadotropin, beta Subunit, HumanPlacentaFetal HeartGastroschisisLive BirthPrenatal Exposure Delayed EffectsPregnancy-Associated Plasma Protein-AMaternal ExposureFetal WeightLogistic ModelsRetinopathy of PrematurityInfant, Newborn, DiseasesPregnancy, TwinHernia, UmbilicalRespiratory Distress Syndrome, NewbornCase-Control StudiesReference ValuesFetal MortalityRegression AnalysisFetal BloodTripletsHeart Rate, FetalFetal Membranes, Premature RuptureHypertension, Pregnancy-InducedDiabetes, GestationalUmbilical ArteriesBody HeightObstetric Labor ComplicationsEmbryonic and Fetal DevelopmentBronchopulmonary DysplasiaPregnancy in DiabeticsFertilization in VitroRegistriesDevelopmental DisabilitiesPerinatal CareIntensive Care, NeonatalOdds RatioLabor, InducedAbortion, InducedInfant, Extremely Low Birth WeightPregnancy Trimesters
OutcomesPretermDiabetesInfantBirthweightAverage gestational ageObesityBirthsEarlier gestationalNeonatalPregnanciesExposureEffects of maternalInfantsCesarean deliveryIntrauterineAbstractFetal growth restMethodsPrenatalNegativelyNeonatesCohortEthnicityIncidenceSerumCharacteristicsSmoking with fetalAbnormalSignificantlyRiskDepressionConcentrationsPlacentalDiagnosisRelationship between maternalEffect of maternalWeight GainPerinatal mentalPrematureNewbornWeeksGenome wideRisksTrajectoriesAnalysesHealth during prStudyInterventionsGlucose metabolismStatistically significantMothersVaginalConfoundersAnalyzePredictorsSensitivity
Outcomes40
  • Maternal prepregnancy hemoglobin concentration has rarely been explored as a risk of poor birth outcomes. (nature.com)
  • Garn SM, Ridella SA, Petzold AS, Falkner F . Maternal hematologic levels and pregnancy outcomes. (nature.com)
  • While the observed associations between DDT and such outcomes might not be causal, the studies are not so flawed that the observations can be dismissed out of hand. (cdc.gov)
  • A health statistics review uses existing health data from data sources like birth certificates and health registries to determine whether health outcomes in a particular community are occurring at a higher, lower, or about the same level compared to statewide or national levels after taking into account factors such as gender and age of individuals within the community. (cdc.gov)
  • The secondary outcomes included incidence of large for gestational age (LGA) babies as defined by birth weight greater than the 90th percentile as well as incidence of SGA and LGA in preterm and term gestations. (thieme-connect.com)
  • Our results suggest that coffee consumption during pregnancy might not itself contribute to adverse outcomes such as stillbirth, sporadic miscarriages and pre-term birth or lower gestational age or birthweight of the offspring. (ntnu.no)
  • Paternal age does not jeopardize the live birth rate and perinatal outcomes after in vitro fertilization: an analysis based on 56,113 frozen embryo transfer cycles. (amedeo.com)
  • There is limited evidence on how the classification of maternal metabolic syndrome during pregnancy affects children's developmental outcomes and the possible mediators of this association. (biomedcentral.com)
  • This study uses a cohort sample of 12,644 to 13,832 mother-child pairs from the UK Born in Bradford Study to examine the associations between maternal metabolic syndrome classification (MetS) and child development outcomes at age 5, using cord blood markers as candidate mediators. (biomedcentral.com)
  • The results support the hypothesis that maternal metabolic syndrome classification during pregnancy is associated with some child developmental outcomes at age 5. (biomedcentral.com)
  • 7 There is little evidence that low-to-moderate alcohol consumption is associated with adverse birth outcomes, 4 , 8 although studies have shown that light-to-moderate consumption (1-4 drinks/week) may be associated with behavioural and mental-health problems in children aged 4-8 years. (bmj.com)
  • As the evolving literature examining birth outcomes increasingly recognizes their multifactorial nature, Dr. Keiser seeks to understand the complex interactions between genetics, environmental context, maternal age and racial/ethnic background that drive both outcomes and disparities. (hopkinsmedicine.org)
  • Background: Maternal sensitivity, or high quality maternal caregiving, in which the mother leads and structures the infant's early experiences in a responsive way, is associated with improved child development outcomes and health, both in the immediate and long term, and thus an important area of public health research. (columbia.edu)
  • Aim: This study investigates the association of several factors: (1) maternal depressive symptomology, (2) breastfeeding, (3) concurrent maternal alcohol intake and (4) infant biological vulnerability upon outcomes of (1) Maternal Sensitivity and (2) Infant Cognitive Development, as well as their effect on the association between senstivity and cognitive development. (columbia.edu)
  • To evaluate associations between maternal anxiety or depression and adverse pregnancy outcomes, taking possible familial confounding and interaction with asthma into account, we conducted a cohort study of all singleton births in Sweden 2001-2013. (diva-portal.org)
  • Some studies have identified relationships between PFAS exposure and reproductive outcomes, although the evidence regarding the pathway and significance of associations is mixed. (biomedcentral.com)
  • Elevated levels of maternal cortisol have been hypothesized as the intermediate process between symptoms of depression and psychosocial stress during pregnancy and adverse birth outcomes. (researchsquare.com)
  • Therefore, we examined associations between cortisol levels in the second trimester of pregnancy and risks of three common birth outcomes in a nested case-control study. (researchsquare.com)
  • Multivariable linear and logistic regression was performed to assess the associations between continuous and categorized cortisol levels and the selected outcomes. (researchsquare.com)
  • The results of this study showed no suggestions of associations between maternal awakening cortisol levels in mid-pregnancy and adverse birth outcomes, except for an increased risk of SGA. (researchsquare.com)
  • Common adverse birth outcomes, including preterm birth, low birth weight, and small-for-gestational age (SGA), are associated with neonatal mortality and long-term health problems, including neurodevelopmental impairments, respiratory and gastrointestinal complications, and higher sympathetic activity, which is considered a risk factor for cardiovascular disease [1-4]. (researchsquare.com)
  • Previous research linked maternal psychosocial problems with increased risks of these birth outcomes, but the underlying mechanisms have not been fully understood yet [5]. (researchsquare.com)
  • It is possible that associations of GWG with outcomes do not result from GWG itself, but rather to underlying factors that influence both weight gain and the outcomes (e.g., maternal diet composition or physical activity level). (nationalacademies.org)
  • 1 , 3 Excess weight at the beginning of pregnancy and excess gestational weight gain (GWG) have been associated with adverse maternal and infant health outcomes such as a large for gestational age (LGA) infant, cesarean delivery, or preterm birth. (uspreventiveservicestaskforce.org)
  • The prevalence of obesity continues to rise and its direct association with multiple co-morbidities has substantial effect on disease outcomes and increased health care spending. (napcrg.org)
  • Adverse birth outcomes, such as early gestational age and low birth weight, can have lasting effects on morbidity and mortality, with impacts that persist into adulthood. (biomedcentral.com)
  • Identifying the maternal factors that contribute to adverse birth outcomes in the next generation is thus a priority. (biomedcentral.com)
  • Epigenetic clocks, which have emerged as powerful tools for quantifying biological aging and various dimensions of physiological dysregulation, hold promise for clarifying relationships between maternal biology and infant health, including the maternal factors or states that predict birth outcomes. (biomedcentral.com)
  • Nevertheless, studies exploring the relationship between maternal epigenetic age and birth outcomes remain few. (biomedcentral.com)
  • Birth outcomes like birth weight, length, and gestational age predict both short- and long-term health. (biomedcentral.com)
  • Experimental work with animal models shows that restricting prenatal nutrition, or imposing acute stress during pregnancy, replicates many of these long-term outcomes in offspring, showing that gestational conditions can have lasting effects on health in the next generation [ 7 , 8 ]. (biomedcentral.com)
  • An association between VOC-contaminated drinking water and adverse late pregnancy outcomes is plausible, but further investigation is needed. (cdc.gov)
  • Further studies are needed to investigate the association and its impact on the development of gestational diabetes, and to establish whether early-gestation or pregestational treatment of SDB would improve glucose metabolic outcomes in pregnancy," they wrote. (mdedge.com)
  • Understanding reasons for the improvements in smoking and physical activity may support the development of targeted interventions to reverse the trends and help prevent chronic disease and adverse reproductive outcomes among women in this age group. (cdc.gov)
  • Preventing and managing these risk factors and conditions in women of reproductive age may improve pregnancy outcomes and the overall health of women. (cdc.gov)
  • The surveillance of trends among women of reproductive age in indicators related to adverse birth outcomes and development of chronic disease can identify groups at increased risk and guide public health prevention and management efforts. (cdc.gov)
  • We expected the association between greenness and birth outcomes to disappear once we accounted for other environmental exposures such as air pollution and noise. (thebump.com)
  • A new paper in the Journal of the American Medical Association found that Nurse-Family Partnership (NFP), a prenatal and early child home visiting program, did not improve birth outcomes for low-income mothers in South Carolina. (scienceblog.com)
  • The randomized evaluation measured maternal and newborn health as a composite outcome indicating whether a participant experienced any of the following adverse birth outcomes: preterm birth, low birth weight, small for gestational age, or perinatal death. (scienceblog.com)
  • As part of the China-Anhui Birth Cohort study, maternal sociodemographic characteristics, food intake, lifestyle, information on vitamin D supplementation, and birth outcomes were prospectively collected. (medscape.com)
Preterm10
  • This study examined whether women with anemia before pregnancy would be at higher risk of preterm birth, low birth weight (LBW) and small-for-gestational-age (SGA) birth. (nature.com)
  • High and low hemoglobin levels during pregnancy: differential risks for preterm birth and small for gestational age. (nature.com)
  • We attempted to estimate the consequences for infant deaths if maternal DDT exposure in fact increases preterm births and decreases the duration of lactation with the strength of association seen in North America. (cdc.gov)
  • This study aimed to determine if hypothyroidism prior to, or during, pregnancy increases the risk of attention-deficit hyperactivity disorder (ADHD) in the child and how the association may be modified by preterm birth, sex of the child, and race-ethnicity. (nih.gov)
  • Stratified analyses were used to evaluate whether the association is affected by timing of first diagnosis, gestational age at birth (term vs. preterm), sex, and race-ethnicity. (nih.gov)
  • Strength of the association was strongest in preterm born infants, boys, and Hispanic children. (nih.gov)
  • No association was observed between moderate drinking and either birth outcome, or between binge drinking and preterm birth. (bmj.com)
  • She has been examining trends at the population level through analyses using a statewide database from California, focusing first on preterm birth, and with plans to extend the analyses to examine both low birth weight and small for gestational age births. (hopkinsmedicine.org)
  • We did not observe any associations between maternal cortisol levels and preterm birth and low birth weight. (researchsquare.com)
  • In this context, we aimed to measure macronutrient content of very preterm milk and to identify changes associated with time and maternal, gestational and neonatal characteristics. (nature.com)
Diabetes26
  • Title : Association of Maternal Body Mass Index, Excessive Weight Gain, and Gestational Diabetes Mellitus With Large-for-Gestational-Age Births Personal Author(s) : Kim, Shin Y.;Sharma, Andrea J.;Sappenfield, William;Wilson, Hoyt G.;Salihu, Hamisu M. (cdc.gov)
  • Gestational diabetes mellitus (GDM) is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy. (medscape.com)
  • Gestational diabetes mellitus accounts for 90% of cases of diabetes mellitus in pregnancy, while preexisting type 2 diabetes accounts for 8% of such cases. (medscape.com)
  • The US Preventive Services Task Force (USPSTF) recommends screening for gestational diabetes mellitus after 24 weeks of pregnancy. (medscape.com)
  • Women with prediabetes identified before pregnancy should be considered at extremely high risk for developing gestational diabetes mellitus during pregnancy. (medscape.com)
  • If maternal diabetes is longstanding or associated with known microvascular disease, obtain a baseline maternal electrocardiogram (ECG) and echocardiogram. (medscape.com)
  • The USPSTF has made recommendations on screening for obesity in adults, screening for gestational diabetes mellitus, and behavioral counseling interventions to promote a healthy diet and physical activity for cardiovascular disease prevention in adults with and without cardiovascular risk factors. (uspreventiveservicestaskforce.org)
  • The primary aim of this study is to investigate the relationship between birth weight for gestational age and weight gain trajectories in early childhood and long term incidence of multiple chronic conditions including cardiometabolic disease risk factors (as Types 1 & 2 diabetes mellitus, hypertension, adult obesity, and hyperlipidemia), Asthma and Polycystic ovarian Syndrom. (napcrg.org)
  • The Cumulative Incidence of different chronic diseases in this cohort by age 30 year are as follows: Hypertension 3.1%, Hyperlipidemia 4.2%, Types 1&2 Diabetes: 1.9%, Asthma 18.0%, PCOS 2.4% (among 4839 females). (napcrg.org)
  • Do Very High BMI and Gestational Diabetes Increase the Likelihood of Having a Child with Autism? (lamaze.org)
  • Are pregnant people who have a high BMI and are diagnosed with gestational diabetes more likely to have children with autism? (lamaze.org)
  • Maternal Obesity, Diabetes Associated with Higher Risk for Autism " and " Maternal Obesity and Gestational Diabetes May Raise Risk of Autism ," no doubt alarming any pregnant person with a GDM diagnosis who ran across them. (lamaze.org)
  • Pooled analysis of the population studies found that maternal diabetes increased the likelihood of having a child with autism by nearly 50% (odds ratio: 1.48). (lamaze.org)
  • That study, by the way, found that the statistically significant association with GDM disappeared after adjusting for gestational age and other factors and was weakened in women with pre-pregnancy diabetes (odds ratios: 1.87 vs. 1.65). (lamaze.org)
  • We investigated the contribution of gestational diabetes mellitus (GDM) to the historic epidemic of type 2 diabetes mellitus (T2DM) in Saskatchewan. (aphapublications.org)
  • 2 Although research has pointed to the influence of rapid environmental and behavioral changes, 2 as well as possible genetic contributors, 3 recent attention has also been directed at the possible role of diabetic pregnancies (gestational diabetes mellitus [GDM] and pre-existing maternal T2DM) in this epidemic. (aphapublications.org)
  • Severe maternal sleep-disordered breathing (SDB) is a known risk factor for gestational diabetes, which is commonly diagnosed in the second or third trimester of pregnancy. (mdedge.com)
  • Now, a new study suggests that increases in insulin resistance, a precursor for gestational diabetes, may take place as early as the first trimester of pregnancy in women with risk factors for obstructive sleep apnea (OSA), such as overweight and habitual snoring. (mdedge.com)
  • What this paper demonstrates is that the changes that predate gestational diabetes are seen much earlier in pregnancy," senior study author Ghada Bourjeily, MD, professor of medicine at Brown University, said in an interview. (mdedge.com)
  • Waiting until midpregnancy to screen for OSA "is too late to make significant changes in the care of these women," said Dr. Bourjeily, who is also director of research and training at the Women's Medicine Collaborative at The Miriam Hospital in Providence, R.I. "By the time you diagnose gestational diabetes, the cat is out of the bag. (mdedge.com)
  • This is an interesting study and one of the rare ones looking at early pregnancy and some of the mechanisms that could possibly be contributing to gestational diabetes," commented Grenye O'Malley, MD, assistant professor in the division of endocrinology, diabetes, and bone disease at the Icahn School of Medicine at Mount Sinai, New York. (mdedge.com)
  • It confirms our suspicions that there's probably a lot of things happening earlier in pregnancy before a diagnosis of gestational diabetes. (mdedge.com)
  • It also confirms that some of the mechanisms are probably very similar to those involved in the association between disordered sleep and the development of type 2 diabetes. (mdedge.com)
  • We recently reported associations between fetal imprinted genes represented as an allele score and both gestational diabetes and maternal glucose concentrations in late pregnancy [ 6 ]. (biomedcentral.com)
  • Recent studies show increases in risk factors for heart disease, diabetes, and cancer in the general population (14-16), but only identified 1 study for women of reproductive age (17). (cdc.gov)
  • Ahluwalia et al highlighted worsening estimates for obesity, smoking, high blood pressure, and diabetes in prevalence estimates from 1991-1992 to 2000-2001 among women of reproductive age (17). (cdc.gov)
Infant16
  • Does Infant Reactivity Moderate the Association Between Antenatal Maternal Depression and Infant Sleep? (bristol.ac.uk)
  • Data con- maternal (100/10 000 live births, 1991) and cerning personal and obstetric history, the infant (78.8/1000 live births, 1998) mortal- current pregnancy and pregnancy outcome ity rates have been recorded [ 8 ]. (who.int)
  • Assuming that these associations are causal, we estimated the increase in infant deaths that might result from DDT spraying. (cdc.gov)
  • If, on the other hand, the estimated increases in infant death rates are similar to or larger than the expected benefits, whether the association is causal matters a great deal, and further investigation is warranted, especially in areas where DDT is reintroduced. (cdc.gov)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. (plos.org)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight. (plos.org)
  • Using restricted National Vital Statistics System data linked birth/infant death data for 1990-2013, we analyze trends in obstetric practices, gestational age distributions, and birth weights among first-birth singletons born to U.S. non-Hispanic White, non-Hispanic Black, and Latina women. (dukeupress.edu)
  • In addition, she is using the Boston Birth Cohort to explore associations between maternal prenatal and perinatal exposures and the risk of infant necrotizing enterocolitis, and understand the extent to which these associations vary by race/ethnicity. (hopkinsmedicine.org)
  • Are maternal depression, breastfeeding, maternal alcohol intake and infant biological vulnerability effect modifiers or confounders of the maternal sensitivity and infant cognitive development association? (columbia.edu)
  • Although previous research has established that exposure to high maternal sensitivity advances the outcome of infant cognitive development, factors such as breastfeeding, which is hypothesized to confound the association, or depression, which is negatively associated with sensitivity, have not yet been examined together in a single study. (columbia.edu)
  • The majority of infant studies examining the maternal sensitivity-infant cognition association include either normal birth weight infants or LBW infant samples. (columbia.edu)
  • Univariate and multi-variable regression analyses were used to examine whether the four maternal factors were associated with Maternal Sensitivity, measured by the Nursing Child Assessment Teaching Scale (NCATS), and with Cognitive Development, measured by the Bayley Scale of Infant Development, Research Edition (BSF-R). (columbia.edu)
  • Conclusion: This research demonstrates that an independent association between maternal sensitivity and infant cognitive development remains even after adjusting for breastfeeding, and that breastfeeding is a separate means to advancing infant cognitive development. (columbia.edu)
  • Several biological mechanisms have been proposed for linking elevated maternal cortisol levels to infant birth weight. (researchsquare.com)
  • Information on the impact of maternal, gestational or neonatal characteristics on milk macronutrient composition could help identify mother-infant pairs at higher risk of extrauterine growth restriction and move towards a more individualized nutritional support [ 24 ]. (nature.com)
  • Mental developmental index (MDI) and psychomotor developmental index (PDI) values were measured using the Korean version of the Bayley Scales of Infant Development II (K-BSID-II) at 24 months of age. (biomedcentral.com)
Birthweight6
  • Objective The aim of the study is to evaluate whether pathologic severity of placenta accreta spectrum (PAS) is correlated with the incidence of small for gestational age (SGA) and neonatal birthweight. (thieme-connect.com)
  • Data including maternal history, neonatal birthweight, and placental pathology were collected and deidentified. (thieme-connect.com)
  • gestational age and pre-term birth (N = 43 568 from the 23andMe, Inc cohort) and birthweight (N = 297 356 reporting own birthweight and N = 210 248 reporting offspring's birthweight from UKBB and the Early Growth Genetics Consortium). (ntnu.no)
  • Although both analyses showed an association between increased coffee consumption and higher birthweight, the magnitude of the effect was inconsistent. (ntnu.no)
  • We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
  • The Association of Maternal Age with Birthweight and Gestational Age: A Cross-Cohort Comparison. (bvsalud.org)
Average gestational age1
Obesity4
Births5
  • [ 1 ] Maternal morbidity and mortality are also increased in pregnancies complicated by multiple gestations and multiple births. (medscape.com)
  • Birthrates of dizygotic twins vary by race (10-40 per 1000 births in blacks, 7-10 per 1000 births in whites, and approximately 3 per 1000 births in Asians) and maternal age (ie, the frequency has risen with increasing maternal age ≤40 years). (medscape.com)
  • Results show that between 1990 and 2013, the likelihood of induced labors and cesarean deliveries increased at all gestational ages, and the gestational age distribution of U.S. births significantly shifted. (dukeupress.edu)
  • Births became much less likely to occur beyond gestational week 40 and much more likely to occur during weeks 37-39. (dukeupress.edu)
  • Overall, nearly 18% of births from not-induced labor and vaginal delivery at later gestational ages were replaced with births occurring at earlier gestational ages from obstetric interventions. (dukeupress.edu)
Earlier gestational1
  • Using a suite of 15 epigenetic clocks, we only found one significant relationship: advanced age on the epigenetic clock trained on leptin predicted a significantly earlier gestational age at delivery ( β = − 0.15, p = 0.009). (biomedcentral.com)
Neonatal2
  • Ie, the neonatal mortality rate in multiple-fetus pregnancies is similar to singleton rates, increasing with decreasing gestational age. (medscape.com)
  • To assess the effect of maternal vitamin D supplementation recommended by the Institute of Medicine (IOM) during pregnancy on the neonatal vitamin D status and the risk of small for gestational age (SGA). (medscape.com)
Pregnancies7
  • Gestational choriocarcinoma can happen during and after any type of pregnancy event, though risk of the disease is higher in and after complete or partial molar pregnancies. (wikipedia.org)
  • Depending on the risk of gestational trophoblastic disease (GTD) development, such as in certain people with mole pregnancies, chemotherapy has been used in a preventative manner in the past. (wikipedia.org)
  • New pregnancies were identified prospectively, dried blood spot samples were collected during the third trimester, and information was obtained on gestational age at delivery and offspring weight after birth. (biomedcentral.com)
  • For pregnancies with medical record data on ultrasound timing, we conducted supplementary tests to model associations by trimester of exposure. (cdc.gov)
  • However, stratified regression models showed no association between increasing ultrasound counts and case status, either for pregnancies without (aOR 1.01, 95% CI 0.92, 1.11) or with ultrasound indications (aOR 1.01, 95% CI 0.95, 1.08). (cdc.gov)
  • The incidence of multiple zygotic pregnancies varies in relation to maternal age, the use of assisted reproductive technology (ART), and ethnicity. (medscape.com)
  • Multiple-gestation pregnancies are associated with a significantly higher maternal complication rate than are singleton gestations. (medscape.com)
Exposure9
  • Here, we use published data on the relationship between DDT spraying and levels in maternal serum and breast milk in Africa to estimate the increased exposure from spraying. (cdc.gov)
  • Also in males, we noted inverse associations between average triclosan exposure over pregnancy and estimated fetal weight combined with birth weight in repeated measures models. (cdc.gov)
  • In conclusion, we observed inverse associations between indicators of maternal phenol exposure during pregnancy and fetal growth, with several differences observed by sex. (cdc.gov)
  • Exposure to maternal hypothyroidism during the periconceptual period significantly increases the risk of ADHD and that the association varies with gestational age at delivery, child sex, and race-ethnicity. (nih.gov)
  • This work supports previous research showing no association between SGA and low-alcohol exposure but adds to evidence of a dose-response relationship with significant risks observed at binge drinking levels. (bmj.com)
  • The association between exposure to secondhand smoke (SHS) during pregnancy and a child's neurodevelopment has not been established yet. (biomedcentral.com)
  • We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
  • We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
  • Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
Effects of maternal2
  • The current study examined associations of mindfulness facets during pregnancy with toddler's social-emotional development and behavior problems, as well as potentially mediating effects of maternal mental health. (researchgate.net)
  • After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy was associated with children's LIT domain through direct effects of maternal metabolic health and indirect effects of cord blood markers (total effects), and COM and PSE domains via changes only in a child's cord blood markers (total indirect effects). (biomedcentral.com)
Infants11
  • A peripheral maternal blood smear was ni infants considered by their mothers to be made by finger prick. (who.int)
  • Evidence from other vaccine-preventable diseases suggests that maternal immunization can provide protection to infants, especially during the high-risk first 6 months of life, through passive transplacental antibody transfer ( 2 ). (cdc.gov)
  • however, no epidemiologic evidence currently exists for the protective benefits of maternal immunization during pregnancy against COVID-19 in infants. (cdc.gov)
  • The Overcoming COVID-19 network conducted a test-negative, case-control study at 20 pediatric hospitals in 17 states during July 1, 2021-January 17, 2022, to assess effectiveness of maternal completion of a 2-dose primary mRNA COVID-19 vaccination series during pregnancy against COVID-19 hospitalization in infants. (cdc.gov)
  • Infants ages 6 months and older are recommended to get the updated COVID-19 vaccine even if born to people who were vaccinated or had COVID-19 before or during pregnancy. (cdc.gov)
  • Society for Maternal-Fetal Medicine Statement: Clinical considerations for the prevention of respiratory syncytial virus disease in infants. (amedeo.com)
  • Using the LBW category may result in potential misclassification since this group combines at least two different phenomena and includes infants who have had either compromised gestational time as in the case of small for gestational age (SGA), or insufficient gestational time, as in the case of premature birth, or both. (columbia.edu)
  • However, none of these studies examine the association between sensitivity and cognitive outcome in infants exclusively premature or SGA. (columbia.edu)
  • It is widely accepted that maternal drug-exposed infants demonstrate excessive early weight loss, but this has not previously been quantified. (bmj.com)
  • For example, early gestational age at birth predicts the two largest causes of death in premature infants: underdevelopment of mature organs and bronchopulmonary dysplasia, a chronic lung disease that damages alveolar tissue [ 1 , 2 ]. (biomedcentral.com)
  • And fewer infants from these areas were considered small for their gestational age. (thebump.com)
Cesarean delivery2
  • We use life table techniques to analyze the joint probabilities of gestational age-specific birth and gestational age-specific obstetric intervention (i.e., induced cesarean delivery, induced vaginal delivery, not-induced cesarean delivery, and not-induced vaginal delivery) to fully document trends in obstetric practices by gestational age. (dukeupress.edu)
  • Findings strongly indicate that recent declines in U.S. birth weight were due to increases in induced labor and cesarean delivery at select gestational ages. (dukeupress.edu)
Intrauterine2
Abstract1
  • ABSTRACT To investigate the consequences of maternal malaria during late pregnancy, we conducted a preliminary study in the 2 hospitals in Al Hodeidah on 276 women who had uncomplicated vaginal deliveries. (who.int)
Fetal growth rest3
  • Maternal vitamin D insufficiency has been associated with fetal growth restriction. (medscape.com)
  • Increasing evidence from observational studies [ 10-17 ] has identified the link between maternal vitamin D deficiency or insufficiency and fetal growth restriction. (medscape.com)
  • Current evidence on maternal vitamin D status and fetal growth restriction derives largely from observational studies, but small supplementation studies. (medscape.com)
Methods3
  • Methods: Using data from the Early Childhood Longitudinal Study-Birth (ECLS-B) Cohort, a nationally representative sample of U.S. born children, depressive symptomology was evaluated as an effect-modifier, and breastfeeding was evaluated as a confounder of the sensitivity-cognitive development association. (columbia.edu)
  • METHODS: This total-population register-based cohort study consisted of 628 312 singleton women born in Sweden between 1973 and 1987, who were followed for diagnosed endometriosis from age 15 years until the end of 2012. (lu.se)
  • METHODS: We used data from the Study to Explore Early Development, a multisite case-control study of preschool-aged children with ASD implemented during 2007-2012. (cdc.gov)
Prenatal3
  • Nurses tailored activities to clients' strengths, risks, and preferences using motivational interviews, educational tools, health assessments, and goal-setting related to prenatal health, child health and development, and maternal life course. (scienceblog.com)
  • BACKGROUND: Studies evaluating the association between prenatal ultrasounds and autism spectrum disorder (ASD) have largely produced negative results. (cdc.gov)
  • OBJECTIVE: To evaluate the association between prenatal ultrasound use and ASD. (cdc.gov)
Negatively2
Neonates2
  • Incidence of Group B Streptococcus early onset sepsis in term neonates with second-line prophylaxis maternal intrapartum antibiotics: A multicenter retrospective study. (amedeo.com)
  • Cord blood levels of 25-hydroxyvitamin D [25(OH)D], calcium, and phosphorus were measured in 1491 neonates who were divided into three groups based on the duration of maternal vitamin D supplementation during pregnancy. (medscape.com)
Cohort1
  • Northstone K. Emmett P. The associations between feeding difficulties and behaviours and dietary patterns at 2 years of age: The ALSPAC cohort . (bristol.ac.uk)
Ethnicity3
  • The association between continuous measures of SDB as a respiratory-event index as well as oxygen-desaturation index and glucose metabolism parameters such as insulin resistance (HOMA-IR) were analyzed after adjusting for gestational age, maternal age, BMI, ethnicity, race, and parity. (mdedge.com)
  • We calculated prevalence ratios over time to assess trends for 4 selected risk factors and 4 chronic conditions, accounting for age, race/ethnicity, education, health care coverage, and individual states. (cdc.gov)
  • [ 7 , 21-23 ] The controversial findings may be due to variations of study designs, including the gestational weeks, dose, season, and adherence of maternal vitamin D supplementation as well as ethnicity of the study population. (medscape.com)
Incidence1
  • Incidence rate differences (IRDs), adjusted hazard ratios (aHRs), and their 95% confidence intervals (CIs) were estimated to evaluate the association of maternal hypothyroidism with childhood ADHD risk. (nih.gov)
Serum3
  • Serum IGF-I was measured in maternal serum from week 14, every fourth week until week 30, and every second week until delivery. (diabetesjournals.org)
  • During pregnancy, serum IGF-I increased with increasing gestational age until a plateau was reached in week 32. (diabetesjournals.org)
  • [ 5 , 6 ] It is noteworthy that fetal and newborn concentrations of 25(OH)D depend on and correlate with maternal serum levels. (medscape.com)
Characteristics2
  • We investigated the associations of maternal and birth characteristics with risk of endometriosis among Swedish women of reproductive age. (lu.se)
  • Multivariable Cox regression was applied to examine associations with perinatal characteristics. (lu.se)
Smoking with fetal1
  • A consistent linear dose-dependent association of maternal smoking with fetal growth was observed from the early second trimester onwards, while no major growth deficit was found in women who quit smoking early in pregnancy except for a shorter FL during late gestation. (plos.org)
Abnormal1
  • Those with gestational choriocarcinoma may experience abnormal vaginal bleeding, abdominal pain, and have high levels of human chorionic gonadotropin (hCG), in addition to history of molar pregnancy or other metastatic cancer. (wikipedia.org)
Significantly2
  • An increase of 0.3 in HOMA-IR related to maternal SDB in early pregnancy may significantly affect glucose metabolism. (mdedge.com)
  • The findings from China suggest that maternal vitamin D supplementation recommended by the IOM results in a slight but significantly higher fetal level of 25(OH)D and improves fetal growth. (medscape.com)
Risk12
  • Risk of disease may also be higher in those experiencing pregnancy at younger or older ages that average, such as below 15 years old or above 45 years old. (wikipedia.org)
  • A health statistics review can take risk factors such as age, race and sex that are commonly found on health records into account. (cdc.gov)
  • Both the two-sample MR and one-sample GRS analyses showed no change in risk of sporadic miscarriages, stillbirths, pre-term birth or effect on gestational age connected to coffee consumption. (ntnu.no)
  • In an Acta Ophthalmologica analysis of 11 relevant articles, maternal smoking during pregnancy was associated with a 46 per cent increased risk. (myvmc.com)
  • Maternal hypothyroidism increases the risk of ADHD diagnosis in the offspring. (nih.gov)
  • Recent longitudinal studies has shown that small for gestational age newborns are at a higher risk of mortality compared to normal or large for gestational age newborns. (napcrg.org)
  • Background: Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. (uib.no)
  • Background: Maternal predictors of folic acid (FA) supplementation use to reduce offspring risk of neural tube defects are well known, while paternal determinants for maternal FA use are less known. (uib.no)
  • This association was partially attenuated by adjusting for maternal glucose concentrations (β = 50 (4-95) g/risk allele, β′ = 0.089, p = 0.03, n = 405). (biomedcentral.com)
  • This study describes recent trends of modifiable risk factors and controllable chronic conditions among reproductive-aged women. (cdc.gov)
  • Data from the 2001 to 2009 Behavioral Risk Factor Surveillance System, a representative state-based telephone survey of health behavior in US adults, was analyzed for 327,917 women of reproductive age, 18 to 44 years. (cdc.gov)
  • A meta-analysis of an observational study reinforced the association between vitamin D deficiency and the risk of small for gestational age (SGA). (medscape.com)
Depression4
  • 2017). The association between non-reacting and child social-emotional behavior in the current study was, against expectation, not mediated by pregnancy distress or postnatal symptoms of anxiety or depression. (researchgate.net)
  • Maternal alcohol use, associated with both breastfeeding and depression, has not been examined in any study investigating the sensitivity-cognitive development association. (columbia.edu)
  • 001), after adjusting for maternal depression and breastfeeding. (columbia.edu)
  • Maybe it's because green spaces lessen depression, boosting maternal health. (thebump.com)
Concentrations10
  • In this study, we sought to assess the association between maternal urinary phenol concentrations in pregnancy and fetal growth. (cdc.gov)
  • Inverse associations were observed between average 2,4- and 2,5-DCP concentrations and birth weight z-scores in males. (cdc.gov)
  • Throughout pregnancy, maternal cortisol levels increase twofold, and cortisol crosses the placenta, accounting for 30-40% of the variability in fetal concentrations [10]. (researchsquare.com)
  • Previously we found that certain fetal imprinted genes represented as an allele score are associated with maternal pregnancy glucose concentrations. (biomedcentral.com)
  • Recently it was reported that fetal polymorphisms with strong associations with birth weight tend to mediate these independently of increases in maternal pregnancy glucose concentrations. (biomedcentral.com)
  • We therefore investigated whether potential associations between the fetal allele score and birth weight were related to maternal glucose concentrations in the Cambridge Baby Growth Study. (biomedcentral.com)
  • The large for gestational age at birth association was also partially attenuated by maternal glucose concentrations. (biomedcentral.com)
  • Genetics can have roles in regulating both maternal glucose concentrations in pregnancy and fetal growth expressed as offspring birth weight. (biomedcentral.com)
  • However none of the fetal variants used to construct the gene score in this study were independently associated with maternal glucose concentrations. (biomedcentral.com)
  • In the current study we therefore examined relationships between our fetal imprinted gene allele score and measures of size at birth, in particular investigating whether any allele score associations with size at birth appear to be attenuated by maternal glucose concentrations in pregnancy. (biomedcentral.com)
Placental2
Diagnosis2
  • It is useful not only for diagnosis but also for monitoring disease progression, treatment response, and potential of recurring gestational choriocarcinoma. (wikipedia.org)
  • The association of maternal hypothyroidism with childhood ADHD was influenced by timing of diagnosis. (nih.gov)
Relationship between maternal1
  • A general linear model was used to assess the relationship between maternal urinary cotinine level and neurodevelopment. (biomedcentral.com)
Effect of maternal1
  • However, the effect of maternal vitamin D supplementation on fetal growth has not been confirmed. (medscape.com)
Weight Gain2
Perinatal mental2
  • Cordero M. Scerif G. Mahedy L. Evans J. Abioye A. Stein A. Maternal perinatal mental health and offspring academic achievement at age 16: the mediating role of childhood executive function . (bristol.ac.uk)
  • Results There was a positive association between maternal non-reacting mindfulness skills and child social-emotional development at 2 years of age, regardless of mothers' perinatal mental health, whereas other mindfulness facets were unrelated. (researchgate.net)
Premature2
  • No association was found between any level of alcohol consumption and premature birth. (bmj.com)
  • Univariate regression analyses showed that of the measures of biological vulnerability, premature birth had the greatest association with both sensitivity and cognitive development in comparison to the LBW or SGA. (columbia.edu)
Newborn1
  • 3. Maternal-Newborn Nursing: A Family-Centered Approach Fifth Ed. Olds, Sally B., et al, 1996. (americanpregnancy.org)
Weeks4
  • If gestational age is 34 weeks or greater, health care providers may recommend being induced for early delivery. (americanpregnancy.org)
  • If gestational age is less than 34 weeks, health care providers will continue monitoring until 34 weeks or beyond. (americanpregnancy.org)
  • Associations with trajectories of estimated fetal weight (EFW) and individual fetal parameters (head circumference, femur length [FL], and abdominal circumference [AC]) from 12-16 to 40 weeks' gestation were analysed using multilevel fractional polynomial models. (plos.org)
  • A total of 192 study participants underwent in-home sleep study (HSAT) and homeostatic model assessment (HOMA) between 11 and 15 gestational weeks, respectively. (mdedge.com)
Genome wide2
  • In a birth weight-related genome wide association study (GWAS) Beaumont et al. (biomedcentral.com)
  • Using genotyping data (564 ASD cases and 715 controls) and external genome-wide association study summary statistics, we computed GI polygenic scores for ulcerative colitis (UC-PGS), inflammatory bowel disease (IDB-PGS), and Crohn's disease (CD-PGS). (cdc.gov)
Risks1
  • World Health Organization (WHO) has recently reported that environmental risks including SHS take lives of 1.7 million children under 5 years of age every year [ 2 ]. (biomedcentral.com)
Trajectories2
  • Background: Research has revealed group-level differences in maternal blood pressure trajectories across pregnancy. (researchgate.net)
  • Growth trajectories will be determined for those with a minimum of 3 measures between ages 0 and 5.5 years. (napcrg.org)
Analyses5
  • We compared results from (1) confounder-adjusted multivariable analyses, (2) a Mendelian randomization (MR) analysis using maternal rs1051730 genotype as an instrument for smoking quantity and ease of quitting, and (3) a negative control analysis comparing maternal and mother's partner's smoking associations. (plos.org)
  • Study limitations include measurement error due to maternal self-report of smoking and the modest sample size for MR analyses resulting in unconfounded estimates being less precise. (plos.org)
  • Here, we attempt to replicate a series of analyses previously reported in a US-based sample, using a larger similarly aged sample ( n = 296) of participants of a long-running study in the Philippines. (biomedcentral.com)
  • We stratified analyses by pre-existing maternal medical conditions and pregnancy complications associated with increased ultrasound use (ultrasound indications) and used logistic regression to model case status by increasing ultrasound counts. (cdc.gov)
  • Trimester-specific analyses using medical record data showed no association in any individual trimester. (cdc.gov)
Health during pr1
  • There is limited evidence from human studies on how maternal cardiometabolic health during pregnancy affects a child's cognitive and behavioural development. (biomedcentral.com)
Study6
  • Chaturvedi N. Callaway M. Day C. Sattar N. Fraser A. The association of nonalcoholic fatty liver disease with central and peripheral blood pressure in adolescence: findings from a cross-sectional study . (bristol.ac.uk)
  • We analysed data from 8,621 European liveborn singletons in 2 population-based pregnancy cohorts (the Generation R Study, the Netherlands 2002-2006 [ n = 4,682]) and the Born in Bradford study, United Kingdom 2007-2010 [ n = 3,939]) with fetal ultrasound and birth anthropometric measures, parental smoking during pregnancy, and maternal genetic data. (plos.org)
  • A two-sample MR study was performed using summary results data from a genome-wide association meta-analysis of coffee consumption (N = 91 462) from the Coffee and Caffeine Genetics Consortium. (ntnu.no)
  • The authors of this study concluded that for any level of maternal glucose concentration fetal genetics has a major impact on growth but acts predominantly through mechanisms independent of maternal glucose. (biomedcentral.com)
  • Ultrasound-derived fat fraction (UDFF) is based on a combination of backscatter coefficient and attenuation parameter.The objectives of the study were to determine (1) agreement between UDFF/MRI proton density fat fraction (MR-PDFF) and (2) whether BMI and age are predictive for UDFF.This cross-sectional prospective study included a convenience sample of 46 children referred for clinically indicated abdominal MRI. (stanford.edu)
  • One hundred women between the ages of 20yrs and 42yrs with a mean age of 28.60±4.95 on their routine antenatal visit were used for the study. (bvsalud.org)
Interventions1
  • Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost? (sigmaaldrich.com)
Glucose metabolism2
  • More severe disturbances in glucose metabolism may have an association. (lamaze.org)
  • That may be true, but I wouldn't let medications that manipulate maternal and possibly fetal glucose metabolism off the hook so easily. (lamaze.org)
Statistically significant1
Mothers2
  • In line with the hypotheses, better non-reacting skills in mothers during pregnancy were associated with more socialemotional capacities in children at 2 years of age. (researchgate.net)
  • No association was evident in children whose mothers had cotinine levels ≤1.90 ng/ml. (biomedcentral.com)
Vaginal1
  • Vaginal bleeding is a common symptom of gestational choriocarcinoma. (wikipedia.org)
Confounders2
  • Models were adjusted for potential maternal, socioeconomic, and child confounders such as maternal education, deprivation, and gestational age. (biomedcentral.com)
  • Maternal alcohol use and biological vulnerability were also hypothesized to be confounders of the sensitivity-cognitive association. (columbia.edu)
Analyze1
  • Studies span different gestational ages, analyze single or pooled samples and use a variety of techniques to determine macronutrient content. (nature.com)
Predictors1
  • Multivariable regression was performed to assess BMI and age as predictors for UDFF.Twenty-two participants were male, 24 were female, and the mean age was 14 ± 3 (range: 7-18) years. (stanford.edu)
Sensitivity5
  • gestational age, attention capacities, and maternal sensitivity was examined in relation to receptive and expressive language functioning in toddlerhood. (uu.nl)
  • At 18 months (corrected age), attention capacities were measured using an eye-tracking procedure and maternal sensitivity was observed during mother-child interaction. (uu.nl)
  • Expressive language was related to maternal sensitivity. (uu.nl)
  • Gestational age and alerting attention capacities specifically were related to language comprehension, whereas maternal sensitivity was related to speech. (uu.nl)
  • 001). Depressive symptomology was not an effect modifier of the sensitivity-cognitive developmental association. (columbia.edu)