Von Hippel-Lindau Tumor Suppressor Proteinvon Hippel-Lindau DiseasePancreatic CystKidney NeoplasmsHypoxia-Inducible Factor 1, alpha SubunitCarcinoma, Renal CellProcollagen-Proline DioxygenaseTumor Suppressor Protein p53Nobel PrizeUbiquitin-Protein LigasesTumor Suppressor ProteinsGenes, Tumor SuppressorHemangioblastomaRho FactorTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2von Willebrand FactorMutationMolecular Sequence DataGenes, p53Nuclear ProteinsProtein BindingGene Expression Regulation, NeoplasticApoptosisGerm-Line MutationDNA-Binding ProteinsNeurofibromin 2Adenomatous Polyposis Coli ProteinTranscription FactorsTransfectionCell LineCell CycleBase SequenceCyclin-Dependent Kinase Inhibitor p16PTEN PhosphohydrolaseProto-Oncogene ProteinsAmino Acid SequenceTumor Cells, CulturedGenes, SuppressorPromoter Regions, GeneticSignal TransductionCell Cycle ProteinsCyclin-Dependent Kinase Inhibitor p21Cell Transformation, NeoplasticCell ProliferationLigasesNeoplasm ProteinsDNA DamageTranscription, GeneticNeoplasmsCell DivisionPhosphorylationCyclinsRNA, MessengerRepressor ProteinsProteinsE2F Transcription Factorsvon Willebrand DiseasesProtein Structure, TertiaryDown-RegulationTranscriptional ActivationBlotting, WesternGerm CellsTumor Markers, BiologicalGene SilencingLoss of HeterozygosityDNA MethylationRNA InterferenceBinding SitesCarrier ProteinsProtein-Serine-Threonine KinasesE2F1 Transcription FactorCell HypoxiaGene Expression RegulationRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionSuppressor of Cytokine Signaling ProteinsSuppression, GeneticRecombinant Fusion ProteinsCells, CulturedFibroblastsTranscription Factor DP1HeLa CellsOncogene Proteins, ViralCell NucleusPapillomavirus E7 ProteinsDNA, NeoplasmWT1 ProteinsDrosophila ProteinsTumor BurdenGene DeletionBreast NeoplasmsDNA PrimersImmunohistochemistryRetinoblastoma-Binding Protein 1Trans-ActivatorsRetinoblastoma-Like Protein p107