• Moreover, although the abundance of most protein groups reflected that of related bacterial populations, we found a specific independent regulation of bacteria-derived cell envelope proteins. (bmj.com)
  • Given the high number of virulence factors present in these bacteria, and the niche-specific role many of them play during different stages of the infectious process, gene expression must be finely tuned in order to efficiently coordinate their expression, and also continue to preserve energy pools. (biomedcentral.com)
  • IMPORTANCE Marine bacteria are part of the healthy microbiota associated with seaweeds, but some species, such as Vibrio spp. (asm.org)
  • Streamlining Regulon Identification in Bacteria Regulons are a group of genes that can be turned on or off by the same regulatory protein. (doe.gov)
  • There are several compounds produced by these bacteria, such as proteins, peptides and components of cell wall that are potential mediators between bacteria and their hosts. (nature.com)
  • The aim of this study is to understand if the production of GABA in bifidobacteria is a strain-specific feature, analyzing the genomic sequence of 1,022 bifidobacterial strains belonging to the currently known 77 Bifidobacterium taxa, representing 70 species and seven subspecies, coupling the in silico information with an in vitro measurements of GABA levels generated by these bacteria. (nature.com)
  • Paenibacillus is a genus of facultative anaerobic , endospore -forming bacteria , originally included within the genus Bacillus and then reclassified as a separate genus in 1993. (wikipedia.org)
  • [8] Bacteria belonging to this genus have been detected in a variety of environments, such as: soil, water, rhizosphere , vegetable matter, forage and insect larvae, as well as clinical samples. (wikipedia.org)
  • bacteria: The colony diameter is 5 cm and the colors indicate the bacterial density (bright yellow for high density). (wikipedia.org)
  • More specifically, several Paenibacillus species serve as efficient plant growth-promoting rhizobacteria (PGPR), which competitively colonize plant roots and can simultaneously act as biofertilizers and as antagonists ( biopesticides ) of recognized root pathogens, such as bacteria, fungi, and nematodes. (wikipedia.org)
  • More extensive genome sequencing could provide fundamental insights into pathways involved in complex social behavior of bacteria, and can discover a source of genes with biotechnological potential. (wikipedia.org)
  • Bacteria are able to compete effectively for iron bound to host proteins because of the secretion of high-affinity, low molecular weight iron chelators known as siderophores. (medscape.com)
  • In order to deprive bacteria of iron, the host also secretes iron-binding proteins. (medscape.com)
  • Borrelia belongs to a genus of bacteria of the spirochete phylum. (prospecbio.com)
  • In Chapter 3, metatranscriptomic sequencing was used to examine the gene expression response of a SO diatom community and their associated bacteria to Fe-amendment incubations during the 2016 WAP cruise. (uri.edu)
  • A genus of gram-negative, aerobic, rod-shaped bacteria usually containing granules of poly-beta-hydroxybutyrate. (lookformedical.com)
  • A genus of gram-negative, aerobic, rod-shaped bacteria that activate PLANT ROOT NODULATION in leguminous plants. (lookformedical.com)
  • Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria. (lookformedical.com)
  • The aim of the present study was to identify the culturable bacteria collected together with isolates of the PLSC from seagrass (Thalassia testudinum) and macroalgae along tropical Atlantic coasts of Mexico, and to explore potential species interactions with selected isolates. (awi.de)
  • A positive correlation was found between the bacterial genera associated with two Prorocentrum clones and the esterified toxin analog DTX1a-D8, but there was no apparent correlation between the other PLSC clones and their associated bacteria with the other five DSP toxins detected. (awi.de)
  • Benthic Prorocentrum and associated bacterial communities comprise highly diverse and characteristic microbiomes upon substrates, and among compartments in culture, but this study provides little evidence that allelochemical interactions among Prorocentrum cells and associated bacteria originating from epibenthic substrates play a definable role in growth and toxigenicity. (awi.de)
  • These can be done on a large scale, such as the tree of life, or on a smaller scale, such as showing all the species of Mycobacterium bacteria. (news-medical.net)
  • For pathogenic bacteria sequences of genes, 16S rRNA, or entire genomes are popular choices of organizational structure. (news-medical.net)
  • Because microorganisms such as bacteria can undergo horizontal gene transfer, genes that are universally conserved across all bacteria are used as markers to ensure accuracy in the alignment. (news-medical.net)
  • Genomic islands are areas of the genome that have been acquired through horizontal gene transfer, and as such, contain genes that are advantageous for bacteria. (news-medical.net)
  • For example, phylogenetic studies on Enterobacteriaceae pathogens have found how antibiotic-resistant genes spread through the family, and that the origin of virulent genomic islands was in phytopathogenic bacteria, meaning pathogens that target plants. (news-medical.net)
  • Bacteria of the genus Brucella are the causative agents of brucellosis, a worldwide zoonosis that affects a broad range of mammals, including livestock and humans. (mgc.ac.cn)
  • The genus Lactobacillus is a phylogenetically diverse group of Gram-positive bacteria. (nature.com)
  • Description and significance== Like most species from the Clostridium genus, ''C. thermocellum'' is a bacteria that has a rod-like shape for its cell body. (kenyon.edu)
  • Heimdallaechaeal mobile elements have garnered various genes from bacteria and bacteriophages, likely playing a role in shuffling functions across domains. (darkenergybiosphere.org)
  • The number of archaea- and bacteria-related genes follow strikingly different scaling laws in Asgard archaea, exhibiting a genome size-dependent ratio and a functional division resembling the bacteria- and archaea-derived gene repertoire across eukaryotes. (darkenergybiosphere.org)
  • In a piece of work carried out by the Carbohydrate Metabolism Research Team of the Institute of Agrobiotechnology, the discovery has been made of the way in which the glgS gene (now renamed as the "surface composition regulator", scoR) acts in bacteria and how the mechanisms involved in bacterial infection can be altered by manipulating this gene, which indirectly affects glycogen production. (europa.eu)
  • As Javier Pozueta, director of the Carbohydrate Metabolism Research Team that carried out the work, explained, "We can say that we may have found an additional way of combating bacterial infections and contamination by encouraging the formation of glycogen in bacteria. (europa.eu)
  • This researcher, who is of Iranian origin, has studied the mechanism of the action of the glgS gene in bacteria and in various Salmonella species, which in certain cases can cause diseases and acute symptoms in humans. (europa.eu)
  • To understand the way in which the glgS gene acts, you have to bear in mind the structure of bacteria. (europa.eu)
  • Is this resistance the result of bacteria evolving new genes in response to the presence of antibiotics, or are antibiotic-resistant bacteria selected for in the environment by possessing antibiotic resistance genes beforehand? (icr.org)
  • To answer these questions a discussion of several factors involved in antibiotic resistance will show that resistance is a designed feature of pre-existing genes enabling bacteria to compete with the antibiotic producers in their environment. (icr.org)
  • A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. (lookformedical.com)
  • The type species of gram negative bacteria in the genus ALCALIGENES, found in soil. (lookformedical.com)
  • This sigma factor is found in a subset of Gram-positive bacteria and has been identified in species as well as in other genera in the order (e.g. and (22). (biotech2012.org)
  • The genus Microbacterium is part of the Phylum Actinobacteria , a group of Gram-positive bacteria present in high concentrations in soils and aquatic sediments. (sdewes.org)
  • Bacteria are ubiquitous in soils, some of them are species of economic value due to their production of compounds such as enzymes, antibiotics and surfactants used for various industrial purposes. (sdewes.org)
  • biodegradable enzymes present in the genes of some bacteria degrade HCH in soil. (ispub.com)
  • Bioinformatics strategies were used to find other homologous genes and proteins, which can also degrade HCH present in various bacteria for controlling of pollution and offer clue to prevent its entry in the food chain. (ispub.com)
  • PCR using the new primer pair on a set of template DNAs of different bacterial genera showed that the method was selective for bacteria belonging to the family Sphingomonadaceae . (ispub.com)
  • In 2014, the MetaHIT consortium by bacteria of the genera Lacto- alytical method used: 66 from 16S published an integrated catalogue bacillus , Prevotella , and Sneathia , rDNA sequencing [11] or 57 from of 10 million bacterial genes de- whereas for infants delivered by whole-metagenome sequencing [5]. (who.int)
  • Microorganisms capable of catabolizing lignin-derived ar- carbohydrate and protein components of the organic matter omatics are essentially fungi and bacteria (Bugg et al. (lu.se)
  • This study determined the prevalence of bacterial contamination of mobile phones of health workers and the predisposing factors, in order to ascertain the risk of transmission of pathogenic bacteria through mobile phones. (bvsalud.org)
  • A total of 112 bacteria belonging to 12 genera were isolated, with predominance of Staphylococcus aureus (31.3%, n=35), Micrococcus spp (30.4%, n=34), coagulase negative staphylococci (10.7%, n=12) and Pseudomonas spp (5.4%, n=6). (bvsalud.org)
  • Bacterial DNA gyrase, a type II DNA topoisomerase found in all bacteria is a proven target for antibacterial chemotherapy. (bvsalud.org)
  • They correspond to functions allowing opportunistic pathogens to colonise the mucus layers, breach the host barriers and invade the mucosae, which could still be aggravated by decreased host-derived pancreatic zymogen granule membrane protein GP2 in CD patients. (bmj.com)
  • New DNA sequencing technologies have enabled detailed comparative genomic analyses of entire genera of bacterial pathogens. (biomedcentral.com)
  • All three human pathogens carry a 70-kb pYV virulence plasmid (also known as pCD), which carries the Ysc type III secretion system and Yops effectors [ 18 - 20 ], that is not detected in non-pathogenic species. (biomedcentral.com)
  • Actinobacteria in the Clavibacter genus are composed of diverse crop pathogens which cause a variety of wilt and cankering diseases. (biorxiv.org)
  • These molecular tools are essential advancements for investigating Gram-positive actinobacteria, particularly for important pathogens in the Clavibacter genus. (biorxiv.org)
  • In other bacterial pathogens, genes important for pathogenicity and host range include secreted protein effectors that suppress host immunity, alter host metabolism, and enable colonization, providing a fitness advantage. (biorxiv.org)
  • Detailed studies of Leptospira proteins and genes that influence pathogenicity make more sense when placed in a phylogenetic context, such as one study showing how genes gained and lost by pathogenic and intermediately pathogenic species since their split from non-infectious species provide increased understanding of how bacterial pathogens change and adapt in response to their hosts. (news-medical.net)
  • Identification of acid-fast bacterial pathogens by acid fast stain / differential stain. (tamu.edu)
  • Importantly all three genera include environmentally transmitted and foodborne pathogens which require the ability to adapt survive and grow in diverse and rapidly changing environments for successful transmission to and from their animal hosts. (biotech2012.org)
  • Each individ- cluding immune cells, but also the was previously cal ed the gastroin- ual harbours hundreds of different metabolic and nervous systems), testinal flora or microflora, the more species, most of which have not and protecting against pathogens pragmatic term "microbiota" is now yet been cultured. (who.int)
  • A comparison of the TF repertoire of S. aureus against 1209 sequenced bacterial genomes was carried out allowing us to identify a core set of orthologous TFs for the Staphylococacceae , and also allowing us to assign potential functions to previously uncharacterized TFs. (biomedcentral.com)
  • We have evaluated the orthologous distribution of these elements in other sequenced bacterial genomes using the repertoire of TFs identified in USA300, and identified a core set of regulators for both the Firmicutes phylum, and the Staphylococacceae group. (biomedcentral.com)
  • The fact that the genus Bacteroides and proteins involved in iron acquisition and metabolism, cell wall, capsule, virulence and mucin degradation were enriched at the end of HBR suggest that both constipation and EC decreased intestinal metal availability leading to modified expression of co-regulated genes in Bacteroides genomes. (frontiersin.org)
  • The deepest branching species in the genus, Y. ruckeri , causative agent of red mouth disease in fish, has the smallest genome (3.7 Mb), although it shares the same core set of approximately 2,500 genes as the other members of the species, whose genomes range in size from 4.3 to 4.8 Mb. (biomedcentral.com)
  • Yersinia genomes had a similar global partition of protein functions, as measured by the distribution of Cluster of Orthologous Groups families. (biomedcentral.com)
  • Here we describe the deployment of new sequencing technology to extensively sample eight genomes from the Yersinia genus of the family Enterobacteriaceae. (biomedcentral.com)
  • The similarities and differences in the genes or genomes are then used to infer how closely related species are based on whether regions have changed, as well as how likely specific regions are to change. (news-medical.net)
  • Pangenome can be classified into conserved core genome (genes/proteins present in all the genomes), a dispensable genome (set of genes shared by multiple genomes, but not all) and unique genes (genes confined to individual organism/genomes) [ 5 ]. (biomedcentral.com)
  • Eukaryotic genomes are known to have garnered innovations from both archaeal and bacterial domains but the sequence of events that led to the complex gene repertoire of eukaryotes is largely unresolved. (darkenergybiosphere.org)
  • Here, through the enrichment of hydrothermal vent microorganisms, we recovered two circularized genomes of Heimdallarchaeum species that belong to an Asgard archaea clade phylogenetically closest to eukaryotes. (darkenergybiosphere.org)
  • These genomes reveal diverse mobile elements, including an integrative viral genome that bidirectionally replicates in a circular form and aloposons, transposons that encode the 5,000 amino acid-sized proteins Otus and Ephialtes. (darkenergybiosphere.org)
  • Moreover, genetic and simple obesity share similar structural and functional features of dysbiosis, such as higher production of toxins with known potential to induce metabolic deteriorations (e.g. trimethylamine-N-oxide and indoxyl sulphate), higher abundance of genomes containing genes coding enzymes involved in the production of these toxic co-metabolites and higher abundance of pathways for biosynthesis of bacterial antigens (such as endotoxin) [13-15]. (deepdyve.com)
  • A catalogue of 178 reference bacterial birth, and the delivery type is the first core of species has been identified genomes distributed among different factor that has an impact. (who.int)
  • Even though diverse strains of S. aureus have been extensively studied, and subjected to genome sequencing, the function of a large proportion of their genes remains unidentified. (biomedcentral.com)
  • Finally, we examine the conservation of 135 USA300 TFs amongst 11 other S. aureus strains, identifying a key group of regulators that display a high degree of conservation, including many that have previously been demonstrated to play a role in virulence gene regulation. (biomedcentral.com)
  • A 3.3-kilobase PvuII fragment carrying the PHR1 gene of Saccharomyces cerevisiae has been cloned into an Escherichia coli expression vector and introduced into E. coli strains deficient in DNA photolyase. (shengsci.com)
  • In this study, 159 bacteriophage strains which had 200 or more orthologous proteins in their genome were examined using the Gene Content Method. (creationresearch.org)
  • Recently, the term "psychobiotic" has been introduced to designate live bacterial strains, including lactobacilli and bifidobacteria, which are able to influence the CNS function 8 . (nature.com)
  • To decipher the molecular basis for the variation in expression and protein production among strains, different regulation levels were analyzed in representative clinical isolates and reference strains. (cnrs.fr)
  • With those exceptions, strains within this genus ferment lactose, most produce highly mucoid colonies on plates because of the production of a luxuriant polysaccharide capsule, and all are nonmotile. (medscape.com)
  • Thus, pangenome analysis is a suitable approach for estimating the diversity in strains of the same species and in rarely in Genera [ 4 ]. (biomedcentral.com)
  • The bacterial pangenome concept was introduced in 2005 for analyzing pathogenic bacterial species and can be defined as the entire set of genes in a group of representative strains of the same genus/species. (biomedcentral.com)
  • 2008. Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes. (mgc.ac.cn)
  • Strains belonging to the same species had identical DGGE fingerprints, and in most cases, these fingerprints were typical for one species. (ispub.com)
  • Some of the enzymes which generate aromatic radicals that break down most prominent bacterial strains found were isolated and tax- the complex linkages present in lignin to compounds of lower onomically identified using 16S ribosomal RNA (rRNA) se- molecular weight. (lu.se)
  • The emergence of certain bacterial strains resistant to antibiotics has become a major public health problem, hence the need to develop new antibiotic molecules. (bvsalud.org)
  • The qac genes of Staphylococcus species encode multidrug efflux pumps: membrane proteins that export toxic molecules and thus increase tolerance to a variety of compounds such as disinfecting agents, including quaternary ammonium compounds (for which they are named), intercalating dyes and some antibiotics. (akjournals.com)
  • RS_01910 may encode a protein related to creatine transport. (frontiersin.org)
  • Because ''C. thermocellum'' is known as a degrader of cellulose, its DNA contains specific nucleotide sequences that make up the genes that encode for the system of enzymes that are necessary for cellulose degradation. (kenyon.edu)
  • Many possess genes that encode proteins to neutralize the affects of antibiotics and prevent attacks on their cell machinery. (icr.org)
  • Mainly, two genes linA and linB encode dehydrochlorinase and dehalogenase enzymes involved in degradation of HCH. (ispub.com)
  • Several genes isolated from resistant enterococci ( agg, gelE, ace, cylLLS, esp, cpd, fsrB ) encode virulence factors such as the production of gelatinase and hemolysin, adherence to caco-2 and hep-2 cells, and capacity for biofilm formation. (medscape.com)
  • Lipopolysaccharides (LPS) are another bacterial pathogenicity factor. (medscape.com)
  • In short, the research team has discovered that there is an inverse correlation between glycogen production and the production of structures involved in bacterial pathogenicity. (europa.eu)
  • In our case we found that the alteration in the expression of glgS, which is only present in the group of enterobacteria ( , species of the Salmonella genus, Yersinia pestis, etc.), has an effect on the production of structures involved in bacterial pathogenicity which, indirectly, affects the capacity to produce glycol gen. (europa.eu)
  • The normal human gut microbiota consists primarily of organisms from two bacterial phyla, Firmicutes and Bacteroidetes, representing 65% and 23% of organisms, respectively [ 3 ]. (springer.com)
  • Nevertheless, these qacA and qacB genes are quite dissimilar to their closest homologues in other organisms. (akjournals.com)
  • The genus Klebsiella belongs to the tribe Klebsiellae, a member of the family Enterobacteriaceae.The organisms are named after Edwin Klebs, a 19th century German microbiologist. (medscape.com)
  • each gains benefits from the other or a relationship between different species where both of the organisms in question benefit from the presence of the other. (lookformedical.com)
  • Most recently, the potential for plant breeding has advanced significantly, with the advent of methods for the incorporation of genes from other organisms into plants via recombinant DNA-techniques. (jrank.org)
  • The increase in resistance among these organisms clearly indicates a change in the frequency of antibiotic resistance genes. (icr.org)
  • With the advances in molecular biology, a new classification era of these organisms arises, with the development of sequencing of specific genes based initially on a small sequence of the 18 s gene, or SSU-rDNA [ 10 ]. (hindawi.com)
  • Enterococcus species are facultative anaerobic organisms that can survive temperatures of 60°C for short periods and that grow in high salt concentrations. (medscape.com)
  • Many carbapenemases are encoded on plasmids, facilitating the spread of resistance genes among organisms of the same species or even different bacterial species. (msdmanuals.com)
  • The effects on physiological markers associated with brush border membrane morphology, intestinal bacterial populations, and duodenal gene expression of key proteins were investigated. (bvsalud.org)
  • It appears that God may have created several kinds of bacteriophages to keep various bacterial populations under control. (creationresearch.org)
  • The discovery of qac genes and their presence in various staphylococcal populations is briefly reviewed. (akjournals.com)
  • Moreover, it is well recognized that the excessive use of broad-spectrum antibiotics can affect the relative proportions of gut microbial populations and foster bacterial resistance [24]. (deepdyve.com)
  • Therefore, it plays an essential biological role in the control of bacterial populations. (hindawi.com)
  • Soil Virus Offers Insight into Maintaining Microorganisms Through a collaborative effort, researchers have identified a protein in soil viruses that may promote soil health. (doe.gov)
  • Colonization of the gut starts just after birth when pioneering species interact, through surface receptors, with gut cells to promote the expression of a specific set of host genes and favour the colonization of commensal microorganisms [6]. (deepdyve.com)
  • Amoebas are unicellular protist microorganisms belonging to the genus amoeba of the family Amoebidae that contains five described genera. (hindawi.com)
  • 11 ] determined that the group of Actinobacteria was one of the most abundant microorganisms in the bacterial community structure in anaerobic digesters of a full-scale municipal wastewater treatment plant. (sdewes.org)
  • By contrast, Bacillus genus microorganisms are large-sized bacilli (4 - 10 μm), Gram-positive, strict aerobic or encapsulated facultative anaerobes. (sdewes.org)
  • The latter served as reference genomic sequences - 3000 such sequences of individual bacterial isolates are currently planned - for comparison purposes during subsequent metagenomic analysis. (wikipedia.org)
  • The project also financed deep sequencing of bacterial 16S rRNA sequences amplified by polymerase chain reaction from human subjects. (wikipedia.org)
  • The plasmids are atypical, as compared to most bacterial plasmids, since they contain many paralogous sequences, a large number of pseudogenes and, in some cases, essential genes. (prospecbio.com)
  • The first steps usually involve aligning the sequences of the various species, helping to identify sequences that are conserved or have remained the same, and sequences that have changed. (news-medical.net)
  • Almost at the same time, reverse vaccinology (RV) emerges as one of the applied approaches to assess the genomic sequences for prediction of novel candidate proteins and their immunogenic epitopes which may elicit protective immune responses [ 7 , 8 ]. (biomedcentral.com)
  • The slightly higher variability of the hsp60 gene sequences with respect to the 16S rRNA sequences offers better opportunities to design or develop molecular assays, allowing identification and differentiation of closely related species. (biomedcentral.com)
  • Total 38 nucleotides and 36 proteins sequences of linA and linB were used for constructing the phylogeny. (ispub.com)
  • Enterococcus faecalis and Enterococcus faecium are the most prevalent species cultured from humans, accounting for more than 90% of clinical isolates. (medscape.com)
  • Bacterial metabolism selected lignin model compounds (vanillin, vanillate, 4- hydroxybenzoate, p-coumarate, benzoate, and ferulate) was carried out with three of the Pseudomonas isolates and in addition with the strain Pseudomonas putida KT2440 from a Introduction culture collection. (lu.se)
  • Fe addition elicited varying responses by different diatom genera, with more prevalent diatoms experiencing more differential regulation of Fe-responsive pathways and proteins. (uri.edu)
  • The multiple degrees of regulation permit the bacterial cell to quickly AMD 070 induce σB activity in response to different environmental circumstances. (biotech2012.org)
  • Twenty-one bacterial genera belonging to Proteobacteria, Actinobacteria, and Bacteroidetes were identified by amplification of the 16S rRNA gene marker from nine clonal Prorocentrum cultures, with g-proteobacteria comprising the dominant class. (awi.de)
  • Bifidobacterium represents one of the largest genus within the Actinobacteria , and includes at present 32 species. (biomedcentral.com)
  • The intergenic DNA segments that are between the ribosomal RNA genes (internal transcribed spacers) and between the tandemly repeated units of rDNA (external transcribed spacers and nontranscribed spacers). (lookformedical.com)
  • These species share a high sequence homology of 16S rDNA and several molecular techniques already applied to discriminate among them give ambiguous results. (biomedcentral.com)
  • The ribosomal operons mainly 16S rDNA has proven to be a stable and specific molecular marker for bacterial identification. (ispub.com)
  • Sequencing of 16S rDNA, sodB, and groEL genes indicated that the bacterium is most likely a novel Ehrlichia species. (cdc.gov)
  • 0.05) decrease in Clostridium genera and E. coli species density with catechin and its synthetic derivative exposure. (bvsalud.org)
  • Important components of the HMP were culture-independent methods of microbial community characterization, such as metagenomics (which provides a broad genetic perspective on a single microbial community), as well as extensive whole genome sequencing (which provides a "deep" genetic perspective on certain aspects of a given microbial community, i.e. of individual bacterial species). (wikipedia.org)
  • Some propose that retroviruses and the associated mobile genetic elements found in various animal species originated from within the host genome and fulfilled structural and regulatory functions, and were later exogenized. (creationresearch.org)
  • P. vortex's genome, for example, [32] harbors many genes which are employed in these strategies, in particular it has the potential to produce siderophores under iron-limiting conditions. (wikipedia.org)
  • Genome to genome variation in islands with genes encoding functions such as ureases, hydrogeneases and B-12 cofactor metabolite reactions may reflect adaptations to colonizing specific host habitats. (biomedcentral.com)
  • For example, critical genes used for specific cell functions are less likely to change than unused sections of the genome, and therefore any changes in critical genes between two species are likely to indicate more distant relatedness. (news-medical.net)
  • Therefore, considering a single representative (genome) from such a species is not sufficient to estimate the exact pangenome and is unfavorable to be targeted for broad-spectrum therapeutics. (biomedcentral.com)
  • Rod-shaped cell body of ''C. thermocellum'']] ==Genome structure== The number of nucleotides present in the genome of ''C. thermocellum'' has been discovered and reported to be at 3,843,301 base pairs which makes up 3307 genes [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=genome&cmd=Retrieve&dopt=Overview&list_uids=20502]. (kenyon.edu)
  • In this study, we undertook extensive genome-wide comparative analyses of twelve species that conform the Pectobacterium genus. (mdpi.com)
  • Without doubt, the investigatory work that revealed the DNA sequence that makes up the Human Genome in 2003 has generated a lot of useful information about DNA, genes and chromosomes. (biotopics.co.uk)
  • The microbiome, the "other ge- species have no representative in nome" or "second genome" of the culture collections. (who.int)
  • Phylogenetic analysis found that the organism was distinct from other known species to a degree consistent with a novel species. (21docs.com)
  • Phylogenetic analysis of these genes identified similarity to a large number of other SMR members, found in staphylococci as well as in other genera. (akjournals.com)
  • The hsp60 gene, coding for a highly conserved 60 kDa heat-shock-protein (a chaperonin), has been evaluated for phylogenetic analysis in bifidobacteria by Jian et al. (biomedcentral.com)
  • 25 ]. The sequence comparison of this gene has been already used for species identification and phylogenetic analysis of other genera (e.g. (biomedcentral.com)
  • Here we explore the feasibility of extracting bacterial protein signals relevant to CD, by interrogating myriads of intestinal bacterial proteomes from a small number of patients and healthy controls. (bmj.com)
  • Results Our 2D-DIGE-based discovery approach revealed an imbalance of intestinal bacterial functions in CD. (bmj.com)
  • MRSA (methicillin-resistant Staphyloccus aureus ) has emerged as an antibiotic-resistant bacterial strain. (biotopics.co.uk)
  • Many of the molecular processes that play a role in the activity and dynamics of the microbiota go beyond species and genic composition and thus, their understanding requires advanced bioinformatics support. (deepdyve.com)
  • Although the precise cause remains unknown, profiling studies of the gut microbiome associate the pathogenesis of IBD, a chronic and relapsing inflammatory disorder of the gut, with the under-representation of certain species in the faecal microbiota [16-19]. (deepdyve.com)
  • The recent success gut microbial genes, obtained after has fantastic potential, it has only of faecal microbiota transplantation, sequencing whole faecal microbiota been about 10 years since the sci- especially in the context of Clostridi- metagenomes from 124 European indi- entific community first realized its im- um difficile infection, argues for such viduals [4]. (who.int)
  • For infants as being present in most individuals, body sites and including 151 repre- that are vaginally delivered, the initial but with different relative abundanc- sentative gastrointestinal species gut microbiota resembles the moth- es. (who.int)
  • We statistically evaluated if intake of added sugar (as well as with the support of the urinary sucrose and fructose biomarker as mentioned in a previous blog post ), sugar-sweetened beverages and artificially sweetened beverages associated with any of the 64 bacterial genera or with various measures of microbiota composition and diversity, such as alpa diversity, beta diversity and the Firmicutes:Bacteroidetes ratio. (lu.se)
  • PCR amplification was performed by using genus-specific primers for the rickettsial 17-kDa protein gene (5′-GCTCTTGCAACTTCTATGTT-3′ and 5′-CATTGTTCGTCAGGTTGGCG-3′) (434-bp PCR fragment) and the outer membrane protein B ( omp B) primers (5′-ATGGCTCAAAAACCAAATTTTCTAA-3′ and 5′-GCTCTACCTGCTCCATTATCTGTACC-3′) (996-bp PCR fragment). (cdc.gov)
  • Two homologs of the outer membrane protein OmpA were identified in Aeromonas salmonicida by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunoblotting, and amino-terminal sequence analyses. (shengsci.com)
  • Expression of ompAI and ompAII separately in E. coli indicated that both genes could be independently transcribed from their own promoters and that both gene products were assembled into the E. coli outer membrane. (shengsci.com)
  • This is the first report of any bacterial species possessing two genes for homologs of this major outer membrane protein. (shengsci.com)
  • They are able to activate complement, which causes selective deposition of C3b onto LPS molecules at sites distant from the bacterial cell membrane. (medscape.com)
  • This inhibits the formation of the membrane attack complex (C5b-C9), which prevents membrane damage and bacterial cell death. (medscape.com)
  • In addition, some diatom genera expressed components of a putative Fe-siderophore uptake system, including an Fe-siderophore outer membrane receptor protein and corresponding ABC transporter components. (uri.edu)
  • The 30-kDa membrane-bound c-type cytochrome protein of mitochondria that functions as an electron donor to CYTOCHROME C GROUP in the mitochondrial and bacterial RESPIRATORY CHAIN. (lookformedical.com)
  • Mycobacterium-specific primers based on 65-kDa heat shock protein (hsp) gene, and Pseudomonas-specific primers based on 16S rRNA gene were used. (cdc.gov)
  • Inactivity and hypoxia resulted in a significant increase in the genus Bacteroides in HBR, in genes coding for proteins involved in iron acquisition and metabolism, cell wall, capsule, virulence, defense and mucin degradation, such as beta-galactosidase (EC3.2.1.23), α-L-fucosidase (EC3.2.1.51), Sialidase (EC3.2.1.18), and α-N-acetylglucosaminidase (EC3.2.1.50). (frontiersin.org)
  • Genes coding for defense-related transcription activators, reactive oxygen species metabolism, terpene biosynthesis, and energy conversion pathways were upregulated in inoculated samples of L. dendroidea , indicating an integrated defensive system in seaweeds. (asm.org)
  • The aim of this work was to determine the maximum concentration of furfural that can be degraded by bacterial consortium metabolism. (sdewes.org)
  • Transcriptomic changes in L. dendroidea in the presence of V. madracius include the upregulation of genes that participate in signaling pathways described here for the first time as a response of seaweeds to microbes. (asm.org)
  • In the bacterial metatranscriptome, upregulation of Fe-siderophore uptake genes was observed, possibly indicating increased competition for Fe among the stimulated diatom-associated bacterial community. (uri.edu)
  • AMD 070 InlA) (15 16 Thus σB-dependent contributions to resilience go beyond simple upregulation of a specific stress response gene. (biotech2012.org)
  • Recent data from preclinical studies suggest a role for neutrophil myeloperoxidase and lipopolysaccharide-binding protein in host defense against K pneumoniae infection. (medscape.com)
  • Investigators showed higher rates of infection in experimental mice deficient in the genes that control expression of these 2 agents. (medscape.com)
  • This article is about treatment of bacterial infection. (wikipedia.org)
  • Acute Bacterial Meningitis Acute bacterial meningitis is rapidly progressive bacterial infection of the meninges and subarachnoid space. (msdmanuals.com)
  • A genus of gram-negative, oxidase-positive, nonfermentative rods which are motile by means of a single flagellum. (lookformedical.com)
  • A genus of gram-negative, aerobic, nonsporeforming rods which usually contain granules of poly-beta-hydroxybutyrate. (lookformedical.com)
  • The Proteeae constitute at least 3 genera of gram-negative. (msdmanuals.com)
  • Chapter 4 investigated how three SO diatoms ( Fragilariopsis cylindrus , Pseudo-nitzschia arenysensis , and Thalassiosira tumida ) interact with associated bacterial communities under Fe stress. (uri.edu)
  • By expanding knowledge about seaweed-bacterium interactions and about the integrated defensive system in seaweeds, this work offers the basis for the development of tools to increase the resistance of cultured seaweeds to bacterial infections. (asm.org)
  • Agrobacterium cells with a genetically-modified plasmid, containing a gene for the desired trait and a marker gene, usually conferring antibiotic resistance, are incubated with protoplasts or small pieces of plant tissue. (jrank.org)
  • The gene encoding Bt, as well as genes conferring resistance to viral diseases, have been introduced into plants by this method. (jrank.org)
  • GM corn and cotton contain bacterial genes that kill insects and confer herbicide-resistance on the crops. (jrank.org)
  • GM squash contains viral genes that confer resistance to viruses. (jrank.org)
  • Microbial species are rapidly evolving and acquiring multi-drug resistance, making existing therapies ineffective [ 1 ]. (biomedcentral.com)
  • Several genes for antibiotic resistance have been identified on plasmids which can be passed between related species. (biotopics.co.uk)
  • To illustrate bacterial exposure to an initial stress condition (e.g. acidic pH in the stomach) not only triggers the AMD 070 expression of acid resistance functions that facilitate survival in this environment but also upregulates the transcription of genes important for survival in subsequent host compartments. (biotech2012.org)
  • However, carbapenem resistance may also be mediated by the loss or alteration of porin channels, the expression of efflux pumps, or penicillin-binding protein (PBP) modification. (msdmanuals.com)
  • Bulk cell-washing of Prorocentrum PA1, followed by growth with antibiotics, was only effective in reducing bacterial load in the initial growth stages, but did not yield axenic cultures or lower bacterial cell densities throughout the culture cycle. (awi.de)
  • Streptomyces-produced quinolone and coumarin antibiotics, such as novobiocin, interfere with a protein called gyrase that assists in the normal separation of double-stranded DNA during replication of DNA or transcription of messenger RNA. (icr.org)
  • Ribosomes, the structures where protein synthesis is catalyzed, are the targets of many other Streptomyces antibiotics such as spectinomycin, tetracycline, and streptomycin. (icr.org)
  • The slight differences between human ribosomes which are not bound by these antibiotics and bacterial ribosomes make this type of antibiotic ideal for treating many illnesses. (icr.org)
  • Other antibiotics, such as penicillin, block the assembly of the bacterial cell wall causing it to weaken and burst. (icr.org)
  • Antibiotics are used to treat or prevent bacterial infections, [29] and sometimes protozoan infections . (wikipedia.org)
  • In each species DNA has been 'added' by horizontal gene transfer in the form of plasmids and genomic islands. (biomedcentral.com)
  • The Borrelia genus members have a linear chromosome which is about 900 kbp in length as well as an excess of both linear and circular plasmids in the 5-220 kbp size range. (prospecbio.com)
  • The virulence of this bacterium results from the 32 Y pestis chromosomal genes and two Y pestis -specific plasmids, constituting the only new genetic material acquired since its evolution from its predecessor. (medscape.com)
  • Many proteins, largely derived from Bacteroides species, were over-represented, while under-represented proteins were mostly from Firmicutes and some Prevotella members. (bmj.com)
  • However, there were no genomic data on the Yersinia species with more limited virulence potential, frequently found in soil and water environments. (biomedcentral.com)
  • Members of this genus are nitrogen-fixing and common soil inhabitants. (lookformedical.com)
  • The ability of Bacillus species of forming highly resistant endospores gives them a very important competitive advantage in an environment such as soil. (sdewes.org)
  • Conclusions This study provides the first evidence that quantifiable bacterial protein signals are associated with CD, which can have a profound impact on future molecular diagnosis. (bmj.com)
  • Recombinant Borrelia Afzelii Outer Surface Protein p100 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 74,782 Dalton. (prospecbio.com)
  • It catalyzes the reduction of FERREDOXIN and other substances in the presence of molecular hydrogen and is involved in the electron transport of bacterial photosynthesis. (lookformedical.com)
  • This work illustrates a simple and cheap molecular tool for the identification of Bifidobacterium species. (biomedcentral.com)
  • Recombinant Borrelia Afzelii Decorin Binding Protein A produced in E.coli is a non-glycosylated, polypeptide chain having a calculated molecular mass of 17,475 Dalton. (assaygenie.com)
  • The protein has a molecular weight of approximately 16,000, contains a single copper atom, is intensively blue, and has a fluorescence emission band centered at 308nm. (lookformedical.com)
  • An A. salmonicida genomic DNA library was constructed by using lambda GEM-11 and recombinant phage carrying both genes ompAI and ompAII) selected by immunoscreening. (shengsci.com)
  • Due to genomic diversity in bacterial species, a large number of variable genes accumulate in species gene pool ultimately resulting in the species pangenome expansion [ 4 ]. (biomedcentral.com)
  • On the other hand, closely related bacterial species share a large number of genomic contents and hence remain less diverge. (biomedcentral.com)
  • A standard curve was developed each for the two model bacterial species Mycobacterium immunogenum and Pseudomonas fluorescens, representing two important genera frequently isolated from MWF. (cdc.gov)
  • A bacterial protein from Pseudomonas, Bordetella, or Alcaligenes which operates as an electron transfer unit associated with the cytochrome chain. (lookformedical.com)
  • Prior to this study, three species of the enterobacterial genus Yersinia that cause invasive human diseases ( Yersinia pestis , Yersinia pseudotuberculosis , and Yersinia enterocolitica ) had been sequenced. (biomedcentral.com)
  • Rapid high-quality draft sequencing was used successfully to compare pathogenic and non-pathogenic members of the Yersinia genus. (biomedcentral.com)
  • Detection of the Salmonella genus by real time PCR. (tamu.edu)
  • A number of phylogenetic trees of SMR Qac proteins are presented here, starting with genes present in S. aureus and S. epidermidis , and extending this to related genes found in other species of this genus, and finally to genes found in other genera. (akjournals.com)
  • Proteins found in any species of bacterium. (lookformedical.com)
  • The dinoflagellate genus Prorocentrum is globally represented by a wide variety of species found upon benthic and/or epiphytic substrates. (awi.de)
  • Most members of the Prorocentrum lima species complex (PLSC) commonly found in the tropics and sub-tropics are toxigenic. (awi.de)
  • It includes more than 200 species found in diverse ecosystems, including the human body and fermented dairy products 1 . (nature.com)
  • The fACCD were found 16.18-82.47 kDa proteins having 149-750 amino acid residues. (springeropen.com)
  • All proteins were found as homo-dimer except ACCNK13, a homo-tetramer. (springeropen.com)
  • 4] Failure of DNA to properly separate during these processes results in a bacterium not being able to divide normally or produce functional proteins. (icr.org)
  • Expression of a Saccharomyces cerevisiae photolyase gene in Escherichia coli. (shengsci.com)
  • Complementation of the E. coli phr-1 mutation was observed, strongly suggesting that the yeast PHR1 gene encodes a. (shengsci.com)
  • Members of the Klebsiella genus typically express 2 types of antigens on their cell surface. (medscape.com)
  • Both classic-pathway and alternate-pathway complement activation have been described, but the latter, which does not require the presence of immunoglobulins directed against bacterial antigens, appears to be the more active pathway in K pneumoniae infections. (medscape.com)
  • Bioinformatics approaches outlined a low nucleotide identity of P. parmentieri and P. wasabiae with other species, while P. carotovorum subsp. (mdpi.com)
  • Conventional identification and classification of Bifidobacterium species have been based on phenotypic and biochemical features, such as cell morphology, carbohydrate fermentation profiles, and polyacrylamide gel electrophoresis analysis of soluble cellular proteins[ 10 ]. (biomedcentral.com)
  • Classification of bacterial organism based on Gram stain characteristic. (tamu.edu)
  • however, few differences and morphological structures led to the lack of classification and differentiation between the diverse species of amoebas [ 9 ]. (hindawi.com)
  • After, universal and conserved genes were used (cytoskeleton actin and tubulin protein genes) that have brought with them greater resolution in the identification and classification of supergroups [ 11 ]. (hindawi.com)
  • Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. (lookformedical.com)
  • In the cytoplasm, a chain or cluster of ribosomes form polyribosomes which function as a continuous protein factory that translates mRNA into polypeptide chains. (kenyon.edu)
  • A species-specific quantitative PCR was designed, and detected the organism within the liver and colon of the index case. (21docs.com)
  • This work underscores the importance of the acquisition of horizontally transferred genes in the evolution of Y. pestis and points to virulence determinants that have been gained and lost on multiple occasions in the history of the genus. (biomedcentral.com)
  • In contrast, the microbial metabolomes, intestinal element and metal profiles, the diversity of bacterial, archaeal and fungal microbial communities were not significantly affected. (frontiersin.org)
  • For example, the relationship between Mycobacterium species tends to show pathogenic species sharing a close relationship with each other and non-pathogenic species clustering together distinctly from the pathogenic species. (news-medical.net)
  • This, in turn, also revealed that many genes present in the non-pathogenic species had been lost from the pathogenic species, presumably influencing their evolution. (news-medical.net)
  • Interestingly, the ACCD is also evident in some plant pathogenic species of Alternaria , Aspergillus , Colletotrichum , and Fusarium that suggests the likely role of ACCD in the ecological fitness of the fungi [ 3 ]. (springeropen.com)
  • 2011. Interactions of the human pathogenic Brucella species with their hosts. (mgc.ac.cn)
  • This review summarizes recent insights into the σB regulon in species including the complex σB-mediated regulatory network interactions that facilitate the integrated and coordinated fine-tuning of physiological functions important for bacterial resilience. (biotech2012.org)
  • It included optimization of the direct DNA isolation from the fluid matrix and the amplification conditions using genus-specific primers. (cdc.gov)
  • The observed progressive decrease in defecation frequency and concomitant increase in the electrical conductivity (EC) preceded or took place in absence of significant changes at the taxonomic, functional gene, metabolome and intestinal metal profile levels. (frontiersin.org)
  • The Pectobacterium genus comprises pectolytic enterobacteria defined as the causal agents of soft rot, blackleg, and aerial stem rot diseases of potato and economically important crops. (mdpi.com)
  • The categories of species pangenome such as core, accessory, and unique genes sets can be analyzed for the identification of vaccine candidates through reverse vaccinology. (biomedcentral.com)
  • Neorickettsia is a genus of obligate intracellular Alphaproteobacteria that are transmitted by digenean trematodes. (21docs.com)
  • This is necessary because most host iron is bound to intracellular and extracellular proteins. (medscape.com)
  • To look for broad-spectrum immunogenic targets and analysis of closely-related bacterial species, the assimilation of pangenome concept into reverse vaccinology approach is essential. (biomedcentral.com)
  • has a high similarity, ranging from 87.7 to 99.5% and bifidobacterial closely related species (e.g. (biomedcentral.com)
  • K pneumoniae and K oxytoca are the 2 members of this genus responsible for most human infections. (medscape.com)
  • It is the most important type of antibacterial agent for fighting bacterial infections , and antibiotic medications are widely used in the treatment and prevention of such infections. (wikipedia.org)
  • The genus Enterococcus includes more than 17 species, although only a few cause clinical infections in humans. (medscape.com)
  • For further characterization, primers were designed to amplify and sequence the groEL gene. (21docs.com)
  • A sequence comparison revealed that some of the PCR primers described in the literature for qac detection may miss particular qac genes due to lack of DNA conservation. (akjournals.com)
  • Three species in the genus Klebsiella are associated with illness in humans: Klebsiella pneumoniae, Klebsiella oxytoca, and Klebsiella granulomatis. (medscape.com)
  • Barrier agains t pathogen s gut bacterial genes in the MetaHIT ation when attempting to extrapolate [10], although Proteobacteria, Ver- catalogue were also well represent- results obtained in mouse models to rucomicrobia, and Fusobacteria are ed in the other metagenomes that the situation in humans. (who.int)
  • QacA and QacB are highly conserved in Staphylococcus species, while qacA was also detected in Enterococcus faecalis , suggesting that these plasmid-born genes have spread across bacterial genera. (akjournals.com)
  • In contrast, SMR-type Qac proteins display considerable sequence variation, despite their short length, even within the Staphylococcus genus. (akjournals.com)
  • Staphylococcus , Corynebacterium , by dietary habits as well as by the ed, the number of frequent genes and Propionibacterium [8]. (who.int)
  • this figure was based on estimates that the human microbiome includes around 100 trillion bacterial cells and an adult human typically has around 10 trillion human cells. (wikipedia.org)
  • The primary amino acid sequence of a protein is a translated version from its gene sequence which carries important messages and information concealed therein. (springeropen.com)
  • The encoded proteins (Mr = 33,564 and 32,536 for mature OmpAI and OmpAII, respectively) had only 64% identity with each other and otherwise had the highest level of homology to OmpA proteins from the members of the family Enterobacteriaceae. (shengsci.com)
  • Following shifts in gut bacterial composition, the immune system surpasses microbial tolerance and progresses to an inflammatory state, which can induce tissue damage throughout the body and promote disease pathogenesis. (springer.com)
  • While offshore and inshore WAP communities differed in species composition, there was little interannual variation. (uri.edu)
  • In this context, DNA-binding transcription factors (TFs) play an important regulatory role by either repressing or activating genes in response to environmental and physiological conditions. (biomedcentral.com)
  • Of the twenty MWF field samples contaminated with mixed microflora, only two samples yielded putative colonies of Mycobacteria and Pseudomonads by culturing method, while seven samples responded to the genus-specific real-time PCR detection and quantification for each genus. (cdc.gov)
  • immunofluorescent assay (IFA) and restriction fragment length polymorphism (RFLP) analyses confirmed the diagnosis and identified the Rickettsia species. (cdc.gov)
  • The assay does not use a host species-specific conjugate and can therefore be used in research to screen mammals other than dogs. (cdc.gov)
  • Most variation between the two proteins was localized to the predicted surface loops and periplasmic turns, while the transmembrane strands and C-terminals domains were highly conserved. (shengsci.com)