• SNPs
  • As most commonly used within SNPedia, genotype refers to the pair of SNPs inherited at a given chromosomal position, one inherited from Dad, one inherited from Mom. (snpedia.com)
  • The increase of interest in SNPs has been reflected by the furious development of a diverse range of SNP genotyping methods. (wikipedia.org)
  • Because DASH genotyping is measuring a quantifiable change in Tm, it is capable of measuring all types of mutations, not just SNPs. (wikipedia.org)
  • phenotypic
  • In this study, researchers were able to suggest a speculative framework for the evolutionary history underlying current-day phenotypic variation in human skin pigmentation based on the similarities and differences they found in the genotype. (wikipedia.org)
  • But the full complexity of the norm of reaction is a function, for each genotype, relating environmental factor to phenotypic trait. (wikipedia.org)
  • A widespread conception is that each genotype gives a certain range of possible phenotypic expressions. (wikipedia.org)
  • Rather, by reducing the picture from two dimensions to just one, it focuses only on discrete, non-overlapping phenotypic expressions, and hides the more common pattern of local minima and maxima in phenotypic expression, with overlapping ranges of phenotypic expression between genotypes. (wikipedia.org)
  • hepatitis C vir
  • Genotype 1b is a strain of the hepatitis C virus that causes a patient to develop hepatitis C, according to the U.S. Department of Veterans Affairs. (reference.com)
  • Hepatitis C virus (HCV) genotypes refer to the genetic variations that occurs in the hepatitis C virus. (wikipedia.org)
  • Hepatitis C virus genotype is considered more common than the Hepatitis B virus infection contributing to more than a million cases annually and is considered one of the major reason for liver transplantation in United states. (wikipedia.org)
  • There are six major genotypes of hepatitis C virus which includes many subtypes. (wikipedia.org)
  • Until recently, there were no specific vaccines available for treating hepatitis C virus genotypes. (wikipedia.org)
  • Populations
  • Traditionally genotyping is the use of DNA sequences to define biological populations by use of molecular tools. (wikipedia.org)
  • According to the hypothesis, the 'thrifty' genotype would have been advantageous for hunter-gatherer populations, especially child-bearing women, because it would allow them to fatten more quickly during times of abundance. (wikipedia.org)
  • In the decades following the publications of his first paper on the "thrifty genotype" hypothesis, Neel researched the frequency of diabetes and (increasingly) obesity in a number of other populations and sought out observations that might disprove or discount his "thrifty gene" hypothesis. (wikipedia.org)
  • affects
  • All the genotypes and its subtypes affects the liver to the same extent of damage irrespective of the HCV genotype Among the common six genotypes, genotype 1 is the most prevalent form in the United States of America, covering around 70-90% of total infections. (wikipedia.org)
  • Genotype 4 and 5 affects a large proportion of the population in undeveloped countries. (wikipedia.org)
  • He went on to advance that the thrifty genotype concept be thought of in the context of a "compromised" genotype that affects several other metabolically-related diseases. (wikipedia.org)

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  • disease
  • While it does not play a significant role in the progression of liver disease as a result of hepatitis, the diagnosis of the genotype is an important factor in determining the length and method of treatment. (reference.com)
  • abundance
  • However, in modern societies with a constant abundance of food, this genotype efficiently prepares individuals for a famine that never comes. (wikipedia.org)
  • Symptoms
  • Some of the HCV genotypes may develop in people without symptoms leading to dangerous conditions like liver cirrhosis causing a permanent damage to liver and the unnoticed HCV conditions will affect brain, joints, blood vessels, bones, and kidneys. (wikipedia.org)
  • individuals
  • It can be demonstrated mathematically that sexual reproduction virtually guarantees that each individual will have a unique genotype (except for those individuals, such as identical twins, who are derived from the same fertilized egg). (britannica.com)
  • Genotyping applies to a broad range of individuals, including microorganisms. (wikipedia.org)
  • common
  • As of 2015, genotype 1 is the most common genotype for Americans diagnosed with hepatitis C and is comprised of subtypes 1a and 1b. (reference.com)
  • The most common use of noninvasive genotyping in medicine is non-invasive prenatal diagnosis (NIPD), which provides an alternative to riskier techniques such as amniocentesis. (wikipedia.org)
  • Genotype 4 is the most common type of infections in Middle east and Africa, around 80% of total infections. (wikipedia.org)
  • People traveling around different subcontinents where several HCV genotypes are common will have the possibility of resulting in mixed infection. (wikipedia.org)
  • medications
  • Standard treatment for genotypes 1, 2 and 3 include medications such as ribavirin, interferon and an antiviral drug, according to Everyday Health. (reference.com)
  • About 15% of the people affected by HCV genotypes will get cured without medications, in which immune system plays a vital role in defeating the virus. (wikipedia.org)