• characteristic
  • One characteristic of bacillary dysentery is blood in stool, which is the result of invasion of the mucosa by the pathogen. (wikipedia.org)
  • HLA-B27 AAU has characteristic clinical features including male preponderance, unilateral alternating acute onset, a non-granulomatous appearance, and frequent recurrences, whereas HLA-B27 negative AAU has an equivalent male to female onset, bilateral chronic course, and more frequent granulomatous appearance. (wikipedia.org)
  • presence
  • Recently, I wanted to see if I could impute the presence of the HLA-B27 antigen using my raw 23andMe DNA data. (csl.name)
  • So the idea is to statistically compare your genome with others whose HLA-B27 presence or absence is known, and then infer the probability that you have it or not. (csl.name)
  • So the probability is a whooping 88.8% for the complete absence of HLA-B27 in this case (but 11.2% for the presence of at least one copy). (csl.name)
  • type
  • Any cell displaying that person's HLA type belongs to that person and, therefore, is not an invader. (wikipedia.org)
  • class
  • HLAs corresponding to MHC class II (DP, DM, DOA, DOB, DQ, and DR) present antigens from outside of the cell to T-lymphocytes. (wikipedia.org)
  • known
  • Because you can't use a service 23andMe to find out if you have HLA-B27: There is no known SNP algorithm that can accurately tell you if you have it (although rs4349859 comes close, but 23andMe doesn't sequence it). (csl.name)
  • complement
  • Among the alternatives to traditional typing by the complement‐dependent cytotoxicity assay, flow cytometric HLAB27 screening is most widely used in general diagnostic laboratories, as it is simple, rapid, and cost effective. (currentprotocols.com)
  • specific
  • When a foreign pathogen enters the body, specific cells called antigen-presenting cells (APCs) engulf the pathogen through a process called phagocytosis. (wikipedia.org)
  • References
  • Four main genotypes of gB have been identified ( 36 ), and it has been proposed that this variation can be correlated with viral tropism in vivo ( 37 ), but it is unclear whether it influences the virulence of HCMV (see reference 44 and references therein). (pubmedcentralcanada.ca)
  • result
  • Although I used a very small reference data set, I managed to get a rough result that happened to coincide with a blood test. (csl.name)
  • And, it did match up with the result of the blood test, which was fun, but could just as well have been pure luck. (csl.name)
  • conditions
  • MHC interacts with TCR and its co-receptors to optimize binding conditions for the TCR-antigen interaction, in terms of antigen binding affinity and specificity, and signal transduction effectiveness. (wikipedia.org)
  • people
  • HLA may also be related to people's perception of the odor of other people, and may be involved in mate selection, as at least one study found a lower-than-expected rate of HLA similarity between spouses in an isolated community. (wikipedia.org)
  • test
  • A blood test will always be more accurate than imputation, but is time consuming and costs money. (csl.name)
  • If a doctor could quickly see that the probability of HLA-B27 is low, and depending on the context, it may not be necessary to order a blood test at all. (csl.name)
  • tools
  • The doctor can then, based on a permission scheme, run imputation for things like HLA-B27 as one of many tools when diagnosing. (csl.name)
  • study
  • Two color analysis of HLAB27 antigen by flow cytometer: A comparative study by conventional microlymphocytotoxicity, DNA genotyping polymerase chain reaction and flow cytometric measurement. (currentprotocols.com)
  • As the study of HLA genetics has evolved and expanded, the nomenclature has been continually altered, posing challenges for those attempting to follow the science. (uptodate.com)