• viral
  • Complications of influenza may include viral pneumonia, secondary bacterial pneumonia, sinus infections, and worsening of previous health problems such as asthma or heart failure. (wikipedia.org)
  • Changes in the viral HA glycoprotein (HA190D/225D) shift receptor specificity from avian to human sialic acids, while a change at amino acid 627 of the PB2 protein to a lysine (627K) allows avian influenza viruses to efficiently replicate in mammalian cells, and at the lower temperatures of the human upper respiratory tract. (virology.ws)
  • Through transcription, the virus then creates copies of mRNA (messenger RNA) and uses them to translate new viral proteins (replication) - essentially creating new virus particles. (studymode.com)
  • The virus achieves such mutations due to the lack of enzymes that correct errors made on the viral genome during replication. (studymode.com)
  • Although we have immunizations against many viral diseases and are adept at treating the symptoms of others, the ability of virus to replicate and mutate allow them almost impossible to stop an ongoing war for centuries. (studymode.com)
  • The viral RNAs that make up the genome are shown as red coils inside the particle and bound to Ribonuclear Proteins (RNPs). (wikipedia.org)
  • Low viral doses are sufficient to infect cottontail rabbits with avian influenza A virus. (amedeo.com)
  • Different from recent cleavage site insertions, the origin of the insert here is not from the viral genome but from host 28S ribosomal RNA (rRNA) instead. (biomedcentral.com)
  • The influenza viral Hemagglutinin (HA) protein is a homo trimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. (sinobiological.com)
  • Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane.The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA0, or hemagglutinin precursor protein. (sinobiological.com)
  • infections
  • This starts with the virus mostly infecting animals, with a few cases where animals infect people, then moves through the stage where the virus begins to spread directly between people, and ends with a pandemic when infections from the new virus have spread worldwide. (wikipedia.org)
  • Until the 2013 outbreak in China, no human infections with H7N9 viruses have ever been reported. (wikipedia.org)
  • deaths
  • Influenza spreads around the world in a yearly outbreak, resulting in about three to five million cases of severe illness and about 250,000 to 500,000 deaths. (wikipedia.org)
  • According to American Medical Association (H1N1 news, n.d.), as of November 12, 2009, data from April 2009 through October 17, 2009 indicates that: there is a total of 20 million people became ill with H1N1, 98,000 hospitalized, and 3,900 deaths. (studymode.com)
  • Seasonal variation in deaths due to influenza or pneumonia in 122 U.S. cities, vs. other causes. (wikipedia.org)
  • HPAI
  • The global HPAI situation significantly improved in the first half of 2008, but the FAO reports that imperfect disease surveillance systems mean that occurrence of the virus remains underestimated and underreported. (wikipedia.org)
  • Replication
  • Type A influenza is an RNA virus that 'reproduces' through replication. (studymode.com)
  • Atkinson NJ, Witteveldt J, Evans DJ, Simmonds P . - The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication . (ed.ac.uk)
  • pneumonia
  • In more serious cases, influenza causes pneumonia, which can be fatal, particularly in young children and the elderly. (wikipedia.org)
  • Clinical evaluation of the isothermal amplification assays for the detection of four common respiratory viruses in children with pneumonia. (amedeo.com)
  • On May 20, 2013, the Taiwan Centers for Disease Control (Taiwan CDC) received a report from a hospital concerning a case of human infection with unsubtypable influenza A virus in a 20-year-old female presenting mild pneumonia who resides in central Taiwan. (blogspot.com)
  • Observational studies indicate that oseltamivir treatment reduces the likelihood of pneumonia, hospitalization and mortality, and the duration of hospitalization in those hospitalized with seasonal or pandemic 2009 H1N1 (A(H1N1)pdm09) virus infection. (infectiousdiseaseadvisor.com)
  • seasonal
  • This virus is contagious and is spreading from person to person worldwide just as seasonal flu viruses spread. (studymode.com)
  • A seasonal decline in the amount of ultraviolet radiation may reduce the likelihood of the virus being damaged or killed by direct radiation damage or indirect effects (i. e. ozone concentration) increasing the probability of infection. (wikipedia.org)
  • surveillance
  • No doubt, this case was picked up due to enhanced surveillance for the H7N9 virus after the outbreak in China, and the subsequent importation of a case to Taiwan in April. (blogspot.com)
  • protein
  • 9. The virus as claimed in the claim 8, wherein the marker gene is Enhanced Green Fluorescent Protein (EGFP) gene. (patentsencyclopedia.com)
  • Influenza viruses are classified into 3 different types (A,B,C) and influenza A is further divided into specific subtypes named after the respective combination of surface protein variants pairing 1 of 17 hemagglutinins (the "H" in HxNx) with 1 of 10 neuraminidases (the "N" in HxNx). (biomedcentral.com)