• These include simulations that can describe the role of enzymes in biological reactions, the configuration of proteins in cell membranes and the design of effective pharmaceutical. (wikipedia.org)
  • The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. (unl.edu)
  • It is found in a variety of enzymes involved in bacterial cell wall degradation. (unl.edu)
  • Xoo genes likely to be associated with pathogenesis include eight with similarity to Xanthomonas avirulence (avr) genes, a set of hypersensitive reaction and pathogenicity (hrp) genes, genes for exopolysaccharide production, and genes encoding extracellular plant cell wall-degrading enzymes. (inra.fr)
  • Many proteins are enzymes that catalyze biochemical reactions and are vital to metabolism. (transectscience.org)
  • The MEROPS database is an information resource for peptidases (also termed proteases, proteinases and proteolytic enzymes) and the proteins that inhibit them. (biokeanos.com)
  • Histone acetyltransferase 1 (Hat1) proteins are conserved enzymes that modify histones by acetylating lysine residues. (sdbonline.org)
  • For instance, many enzymes, such as protein kinase A here, form a cleft that can recognize and bind polypeptide loops of their binding partners. (jove.com)
  • Moreover, the gene products of structural genes can be either enzymes, hormones or proteins, which form structural components of the cell. (pediaa.com)
  • Circular DNA sequences are present in bacterial, mitochondrial and cancer genomes, and offer promise for the design of gene vectors. (wikipedia.org)
  • The co-chaperone Hep1 is required to prevent the aggregation of mitochondrial Hsp70 proteins. (cipsm.de)
  • Electron cryoEM structures of mitochondrial, chloroplast, and bacterial ATP synthases have revealed the architecture of the FO region, helping to explain the mechanisms of proton translocation, dimerization of the enzyme in mitochondria, and cristae formation. (tcdb.org)
  • Within the cell, HABP1 binds to molecules containing the C1q globular domain, multiple isoforms of PKC, mitochondrial Hrk, the cytoplasmic tails of adrenergic and GABA-A receptors, the mRNA splicing factor ASF/SF2, and the CBF transcription factor (10 - 16). (rndsystems.com)
  • PA-X is a nonstructural protein of influenza A virus (IAV), which is encoded by the polymerase acidic (PA) N-terminal region that contains a C-terminal +1 frameshifted sequence. (bvsalud.org)
  • The product of the recently discovered ybfF gene, which belongs to the esterase family, does not show high sequence similarity to other esterases. (inra.fr)
  • The interolog method relies on protein sequence similarity to conduct the PPI prediction. (biomedcentral.com)
  • A method for determining the sequence specificity of DNA-binding proteins. (lookformedical.com)
  • Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity. (transectscience.org)
  • The sequence of amino acid residues in a protein is defined by the sequence of a gene which is encoded in the genetic code. (transectscience.org)
  • To unravel the provenance and relationships of the MORC family, we initiated sequence profile searches using the PSI-BLAST program seeded with eukaryotic MORC proteins. (beds.ac.uk)
  • ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS -binding ParB-CTPase and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids. (biorxiv.org)
  • The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry. (pacb.com)
  • Here we report a draft genome sequence of the G-type, and re-sequencing of the P-type for comparison. (pacb.com)
  • Draft genome sequence of Micromonospora sp. (pacb.com)
  • Complete genome sequence of Kosakonia oryzae type strain Ola 51(T). (pacb.com)
  • Here we summarize the features of the strain Ola 51(T) and describe its complete genome sequence. (pacb.com)
  • AtPNP-A has distant sequence homology with human ANP, a protein that forms amyloid fibrils in vivo . (encyclopedia.pub)
  • Amyloid forming proteins do not share any similarity in sequence or native structure, albeit amyloid fibrils are characterized by a common structure, known as "cross-β" structure. (encyclopedia.pub)
  • Near-Complete Genome Sequence of Lötschberg Virus (Mononegavirales: Filoviridae) Identified in European Perch (Perca fluviatilis Linnaeus, 1758). (unibe.ch)
  • The genome includes 4637 open reading frames (ORFs) of which 3340 (72.0%) could be assigned putative function. (inra.fr)
  • Using shotgun metagenomics from skin swabs of healthy individuals and patients with AD, we found 13,586 potential viral contiguous DNA sequences, which could be combined into 164 putative viral genomes including 133 putative phages. (microbial-ecology.net)
  • ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. (unl.edu)
  • Short polypeptides, containing less than 20-30 residues, are rarely considered to be proteins and are commonly called peptides, or sometimes oligopeptides. (transectscience.org)
  • Amyloid fibrils are formed by proteins or peptides, that under certain conditions self-assemble into characteristic fibrillar structures [ 1 ] . (encyclopedia.pub)
  • The Database of Protein Disorder (DisProt) is a curated database that provides information about intrinsically disordered proteins that lack fixed 3D structure in their putatively native states, either in their entirety or in part. (biokeanos.com)
  • While antioxidative stress proteins, antiapoptotic pathways and tardigrade-specific intrinsically disordered proteins have been implicated in the anhydrobiotic machinery, conservation of these mechanisms is not universal within the phylum Tardigrada, suggesting the existence of overlooked components. (biomedcentral.com)
  • The eukaryotic proteins are more complicated than the bacterial enzyme complexes. (tcdb.org)
  • Proteins can also work together to achieve a particular function, and they often associate to form stable protein complexes. (transectscience.org)
  • The common ancestor of these GHKL proteins, MutL and topoisomerase ATPase modules appears to have catalyzed structural reorganization of protein complexes and concomitant DNA-superstructure manipulations along with fused or standalone nuclease domains. (beds.ac.uk)
  • In fact, a large number of proteins need to form protein complexes or oligomers to carry out their functions. (jove.com)
  • Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. (jove.com)
  • Nucleic acid sequences involved in regulating the expression of genes. (lookformedical.com)
  • Cis-acting DNA sequences which can increase transcription of genes. (lookformedical.com)
  • The SWISS-MODEL Repository is a database of annotated 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline for protein sequences of selected model organisms. (biokeanos.com)
  • The database gives access to protein sequences, nucleic acid sequences and structural information on conopeptides. (biokeanos.com)
  • Through time-series transcriptome analysis of Ramazzottius varieornatus specimens exposed to ultraviolet light and comparison with anhydrobiosis entry, we first identified several novel gene families without similarity to existing sequences that are induced rapidly after stress exposure. (biomedcentral.com)
  • Computer programs can predict PPIs based on similar interactions found in other proteins by comparing protein sequences and three-dimensional structures. (jove.com)
  • Plastid-specific ribosomal proteins (PSRPs) have been proposed to play roles in the light-dependent regulation of chloroplast translation. (cipsm.de)
  • We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)
  • The provenance and biochemical roles of eukaryotic MORC proteins have remained poorly understood since the discovery of their prototype MORC1, which is required for meiotic nuclear division in animals. (beds.ac.uk)
  • Consistent with a chromatin-associated role, the MORCs display fusions to several DNA- and peptide-binding domains, which are commonly found other eukaryotic chromatin proteins [ 5 ]. (beds.ac.uk)
  • The prokaryotic and eukaryotic MORC homologs were unified to the exclusion of the other GHKL proteins by a specific GhXhhpXXRhl motif (h: hydrophobic, p: polar, X: any) in the S5-fold domain (Fig. 1 ). (beds.ac.uk)
  • This interface is observed frequently in proteins that contain leucine zipper domains such as eukaryotic transcription factors. (jove.com)
  • In response, cells produce the interferon inducible RNA-dependent protein kinase (PKR) that, when bound to viral dsRNA, phosphorylates eukaryotic initiation factor 2αand attenuates viral protein translation. (uleth.ca)
  • Protein conformation is critically linked to function and often controlled by interactions with regulatory factors. (cipsm.de)
  • Further, biophysical experiments suggested that HomA and HomB are dimeric and most likely the cysteine residues present on surface-exposed loops participate in protein-protein interactions. (nature.com)
  • The presence of these genes provides insights into the interactions of this pathogen with its gramineous host. (inra.fr)
  • Protein-protein interactions (PPIs) play a critical role in initiating pathogenesis and maintaining infection. (biomedcentral.com)
  • In this study, we used two computational approaches, the interolog and the domain-based to predict the interactions between Arabidopsis and PstDC3000 in genome scale. (biomedcentral.com)
  • PDBsum provides an overview of every macromolecular structure deposited in the Protein Data Bank (PDB), giving schematic diagrams of the molecules in each structure and of the interactions between them. (biokeanos.com)
  • Many biological processes depend on protein-protein interactions. (jove.com)
  • Similar to ligand binding sites, interactions at a protein-protein interface may involve non-covalent bonds and hydrophobic forces. (jove.com)
  • Laboratory methods, such as affinity purification, mass spectrometry, and protein microarrays, can be used to identify new interactions. (jove.com)
  • Cellular function is based on protein-protein interactions. (sciencegate.app)
  • A large proportion of these interactions involves the binding of short linear motifs (SLiMs) by folded globular domains. (sciencegate.app)
  • We provide examples of SLiM-based interactions that are turned on/off, or are tuned by serine/threonine phosphorylation and exemplify how this affects SLiM-based protein complex formation. (sciencegate.app)
  • PRRSV employs −1 PRF directed by RNA secondary and tertiary structures within its viral genome (canonical PRF), as well as a noncanonical −1 and −2 PRF that are stimulated by the interactions of PRRSV nonstructural protein 1β (nsp1β) and host protein poly(C)-binding protein (PCBP) 1 or 2 with the viral genome. (uleth.ca)
  • Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. (unl.edu)
  • A Pseudomonas protein and an Arabidopsis protein are predicted to interact with each other if an experimentally verified interaction exists between their respective homologous proteins in another organism. (biomedcentral.com)
  • Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins. (shengsci.com)
  • Harris was involved with the development of Fluctuating Finite Element Analysis, a mesoscale modelling tool that makes use of contiuum mechanics used to predict bimolecular dynamics in globular macromolecules and proteins. (wikipedia.org)
  • Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. (transectscience.org)
  • Like other biological macromolecules such as polysaccharides and nucleic acids, proteins are essential parts of organisms and participate in virtually every process within cells. (transectscience.org)
  • The Protein Data Bank (PDB) is an archive of experimentally determined three-dimensional structures of biological macromolecules that serves a global community of researchers, educators, and students. (biokeanos.com)
  • The Protein Data Bank is the single worldwide archive of structural data of biological macromolecules. (biokeanos.com)
  • Various interior dynamics including self organization of macromolecules, protein conformation, movement of human thoracic diaphragm, formation of logarithmic spiral in nature were discussed in the light of potential energy of self gravity and kinetic energy of metabolic energy. (webmedcentral.com)
  • See how the University of Washington used HiFi sequencing to uncover a key finding about ALS and the human genome. (pacb.com)
  • Three transketolase genes have been identified in the human genome to date: transketolase (TKT), transketolase-like 1 (TKTL1) and transketolase-like 2 (TKTL2). (biomedcentral.com)
  • Abstract ARAP2 is an Arf GAP that has previously been reported to affect focal adhesions (FAs) by regulating Arf6 and integrin trafficking and to bind to the adaptor proteins APPL1. (bio2009.org)
  • VCP identifies ubiquitylated substrates through numerous dedicated adaptor proteins and unfolds substrates by threading them through a central pore in the hexamer ( Figure 1 ). (portlandpress.com)
  • VCP interacts with adaptor proteins to identify ubiquitylated substrates for degradation by the proteasome. (portlandpress.com)
  • The AAA-ATPase (ATPases associated with diverse cellular activities) valosin-containing protein (VCP), is essential for many cellular pathways including but not limited to endoplasmic reticulum-associated degradation (ERAD), DNA damage responses, and cell cycle regulation. (portlandpress.com)
  • VCP primarily identifies ubiquitylated proteins in these pathways and mediates their unfolding and degradation by the 26S proteasome. (portlandpress.com)
  • Valosin-containing protein (VCP, also p97, or Cdc48p in yeast) is an evolutionarily conserved, homo-hexameric, ubiquitin-selective, AAA-ATPase that functions in numerous ubiquitin-dependent protein quality control pathways. (portlandpress.com)
  • Our study provides essential structural information of unexplored proteins of the Hom family that can help in a better understanding of H. pylori pathogenesis. (nature.com)
  • Outer membrane proteins (OMPs) of H. pylori play a crucial role in the host-pathogen interaction, virulence and pathogenesis. (nature.com)
  • investigated pathogenesis and immunological response caused by HomB protein in clinical patients and 190 H. pylori strain isolated from patients with peptic ulcer disease (PUD) or gastritis were evaluated for the clinical importance of homB . (nature.com)
  • It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. (unl.edu)
  • Basically, Pseudomonas syringae pathogenesis is dependent on effector proteins and to date, nearly 60 different type III effector proteins encoded by hop genes have been identified [ http://www.pseudomonas-syringae.org/ ]. (biomedcentral.com)
  • The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. (cipsm.de)
  • Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. (lookformedical.com)
  • In mice, rapamycin treatment increases expression of histone proteins and Wdfy3 transcription, and alters chromatin organisation in the small intestine, suggesting the mTORC1-histone axis is at least partially conserved in mammals and may offer new targets for anti-ageing interventions. (sdbonline.org)
  • The transcription of the beta-globin genes in mouse erythroleukemia cells has been examined by hybridizing labeled RNA obtained from isolated nuclei after chain elongation in the presence of [alpha-32P]UTP. (shengsci.com)
  • Moreover, the expression of a particular structural gene is regulated by a specific regulatory gene, while these regulatory genes mainly occur 5′ to the transcription start site of the structural gene. (pediaa.com)
  • Moreover, the gene products of the regulatory genes can be either protein, which serves as transcription factors, or regulatory RNAs. (pediaa.com)
  • Here, transcription factors bind to the promoter or operator region of the structural gene. (pediaa.com)
  • The idea has caught on, and now many scientists are exploring how such physical processes can drive the formation of the cell's structures and play key roles in cellular division and gene expression. (princeton.edu)
  • IAV PA-X protein modulates virus-induced host innate immune responses and viral pathogenicity via suppression of host gene expression or cellular shutoff, through cellular mRNA cleavage. (bvsalud.org)
  • In the present study, we describe a novel bacterium-based approach to identify amino acid residues in the PA-X protein of the HPAIV A/Viet Nam/1203/2004 H5N1 that are important for its ability to inhibit host protein expression or cellular shutoff activity. (bvsalud.org)
  • ybfF protein from Escherichia coli (Ec_ybfF) belongs to the esterase family for the large substrates, palmitoyl coenzyme A and malonyl coenzyme A, which are important cellular intermediates for energy conversion and biomolecular synthesis. (inra.fr)
  • Finally, US11 has been recently shown to also counteract the activity of the 2'-5' oligoadenylate synthetase (OAS), a cellular protein critical for host cell defense [ 15 ]. (biomedcentral.com)
  • Highly structured RNA derived from viral genomes is a key cellular indicator of viral infection. (uleth.ca)
  • This special polyclonal antibody provides a good tool for further studying structural and functional characterization of HSV-1 US11 protein. (biomedcentral.com)
  • Characterization of the comparison between each group with the photoconvertible fluorescent protein to allow merozoite egress voltaren online purchase. (itwontfailbecauseofme.com)
  • Here we demonstrate that PSRP1 is not a bona fide ribosomal protein, but rather a functional homologue of the Escherichia coli cold-shock protein pY. (cipsm.de)
  • DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)
  • Analysis of the ~7.1-Mb genome provides insight into this strain's biosynthetic potential, means of regulation, and response to coculturing conditions. (pacb.com)
  • Post-translational modifications of histone proteins play a pivotal role in DNA packaging and regulation of genome functions. (sdbonline.org)
  • LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. (unl.edu)
  • Phyletic analysis showed that the MORC proteins are widely distributed in eukaryotes, being present in most major crown group lineages (except fungi), apicomplexans and heteroloboseans, suggesting a relatively early origin in eukaryotes [ 5 ]. (beds.ac.uk)
  • Generally, structural genes occur in both prokaryotes and eukaryotes. (pediaa.com)
  • Therefore, structural genes in eukaryotes are large in size. (pediaa.com)
  • Structural and regulatory genes are the two types of genes in the genome of both prokaryotes and eukaryotes. (pediaa.com)
  • VCP assembles primarily as a homo-hexamer comprised of six monomers, each of which contains a globular N-domain and two ATPase domains (D1 and D2). (portlandpress.com)
  • SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes. (biokeanos.com)
  • In other cases, different proteins or polypeptides come together to form a functional unit. (jove.com)
  • Besides, gene products of structural genes have either structural or functional importance, while regulatory genes regulate the expression of structural genes. (pediaa.com)
  • Nucleic acid having higher density finds place as 'core', medium denser protein in intermediate and least dense fat in the periphery. (webmedcentral.com)
  • Explanation: Nitrogen is required by plants in a great amount as its constituent amino acids, nucleic acid, amides, proteins, nucleotides, and coenzymes. (sanfoundry.com)
  • RNA-seq analysis of embryos indicate that in Hat1 mutants over 2000 genes are dysregulated and the observed transcriptional changes imply a delay in the developmental program of gene expression (Varga, 2019). (sdbonline.org)
  • We identify the prokaryotic MORCs and establish that the MORC family belongs to a larger radiation of several families of GHKL proteins (paraMORCs) in prokaryotes. (beds.ac.uk)
  • This is suggestive of extensive lateral transfer of these genes between diverse prokaryotes. (beds.ac.uk)
  • On the other hand, functionally-related structural genes in prokaryotes occur in clusters called operons. (pediaa.com)
  • To date, the function of US11 protein in cell culture and animal models is poorly understood. (biomedcentral.com)
  • Moreover, PRIN2 and CSP41b form a distinct protein complex in vitro that binds DNA. (frontiersin.org)
  • Crystallographic study of this protein suggested Zn or Mn binding at the active site, and we further confirmed that this protein has Mn-dependent peroxidase activity in vitro. (biomedcentral.com)
  • Co-immunoprecipitation of proteins and yeast two-hybrid screening are widely used to provide evidence on whether two proteins interact in vitro . (jove.com)
  • The PEP enzyme recognizes the -10 and -35 cis -elements, similar to those found in bacterial promoters whereas the NEP enzyme recognizes the YRTA-motif, which can also be found upstream of several genes with PEP promoters indicating that these genes can be transcribed by both polymerases ( Pfannschmidt and Liere, 2005 ). (frontiersin.org)
  • These regulatory factors control the expression of one or several genes. (pediaa.com)
  • Additionally, in a phylogenetic tree versions from the same bacterial lineage (e.g. proteobacteria) often do not group together. (beds.ac.uk)
  • Hom (Helicobacter outer membrane) family of OMPs in H. pylori consists of four members (HomA, B, C and D). In the H. pylori genome jhp 0870 open-reading frame (ORF) that codes for HomB outer membrane protein is associated with many stomach diseases and is a novel co-marker for peptic ulcer disease (PUD) 9 , 10 . (nature.com)
  • There are currently 20 retinal genes whose mutations cause the phenotype of LCA, accounting for about 70% of the cases, while the genes underlying the remaining 30% of patients await discovery. (aao.org)
  • Visual acuity (VA) in children with LCA varies significantly among patients with differing gene mutations and can be as low as no light perception (NLP). (aao.org)
  • We find that phage populations with single target mutations depend on location of enriched phage mutations in early autophagy protein EPG-9 also result in abnormal accumulation of ATG-9 and the pre-autophagosomal structure. (itwontfailbecauseofme.com)
  • The SARS-CoV-2 variants (including alpha, beta, delta, and omicron) that have driven the COVID-19 pandemic all stem from mutations in the virus's genome which changed the virus's structure, making the virus more difficult for our immune systems to recognize and defend against. (learn-biology.com)
  • During productive infection, the 152-kb double-stranded HSV-1 genome is rapidly translocated to the nucleus where at least 80 viral genes are transcribed by the host cell RNA polymerase II (Pol II) [ 1 ]. (biomedcentral.com)
  • Here we report the selection of camelid-derived single-domain antibodies (nanobodies) that modulate the conformation and spectral properties of the green fluorescent protein (GFP). (cipsm.de)
  • These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. (unl.edu)
  • FAs are structures composed of clustered transmembrane proteins called integrins that bind to the extracellular matrix and link to the actin cytoskeleton and control cell migration, proliferation, survival and differentiation (Gardel et al. (bio2009.org)
  • Cell surface HABP1 binds a wide range of extracellular molecules, including hyaluronan, vitronectin, complement component C1q, HMW kininogen, and bacterial and viral proteins (2, 6 - 9). (rndsystems.com)
  • On the other hand, regulatory mRNAs, including siRNA and miRNA , act on the RNA transcribed from the structural gene. (pediaa.com)
  • Moreover, our results demonstrate the feasibility of using this bacterium-based approach to identify amino acid residues important for the activity of viral proteins to inhibit host gene expression. (bvsalud.org)
  • view conditions 3 and 4 to effect the quick efficiency in the ethylene analyzed in direction This will have in the time uptake incorporated in contamination plant of protein( trait4 The comprising of the nuclear network inspection, strategy, is chosen in ultra- In intercept, it gives highly the New low produced by the hazard to generate addition model transfer 3, expression. (scoutconnection.com)
  • The US11 gene was cloned into the prokaryotic expression vector pET-32a (+) to express His-tagged US11 protein in Escherichia coli. (biomedcentral.com)
  • In the present study, we obtained a high-level expression of the recombinant US11 protein as well as high titers of rabbit polyclonal antibody specially against US11 protein in HSV-1 infected cells. (biomedcentral.com)
  • Also, their binding either induce or repress the expression of the structural gene. (pediaa.com)
  • Structural genes refer to a gene that codes for any RNA or protein product other than a regulatory factor, while regulatory genes refer to a gene involved in controlling the expression of one or more other genes. (pediaa.com)
  • But for more left been view Ду slopes, there are available subjects to using the reduction of genomes only longitudinal. (scoutconnection.com)
  • In the ebook работа пианиста с нотными примерами of valuable decades of traditional activators of chemical results commenting non-genotyped oils and points( which proves a longitudinal biglycan in a native stationary methods), intensive events contain a so abdominal decomposition to model longitudinal proteins that can require impeccably chosen from the non-normal abundance of disappearance. (naturheilpraxis-gisbert-fussek.de)
  • ARAP2 associates with adaptor protein with PH domain, PTB domain and leucine zipper motifs 1 (APPL1) in endosomes (Chen et al. (bio2009.org)
  • The domain-based method uses domain interaction information, which is derived from known protein 3D structures, to infer the potential PPIs. (biomedcentral.com)
  • The Protein Data Bank in Europe (PDBe) is the European resource for the collection, organisation and dissemination of data on biological macromolecular structures. (biokeanos.com)
  • a plastid-encoded bacterial-type RNA polymerase (PEP) and a nuclear-encoded phage-type RNA polymerase (NEP), which recognize distinct types of promoters. (frontiersin.org)
  • Genes corresponding to a B-family type polymerase ('polB') and an HNH nuclease ('HNH') are marked. (elifesciences.org)
  • In the blood vascular system, human serum albumin (HSA) is a vital globular transport protein with potential multiple ligand binding sites. (researchgate.net)
  • Such a peculiar arrangement of phenylalanyl residues at the distal ligand binding site has not been observed before in the globin family, and is unique to HbI, a protein functionally devoted to sulfide transport. (shengsci.com)
  • Pseudomonas syringae is a major bacterial leaf pathogen that causes diseases in a wide range of plant species. (biomedcentral.com)
  • Proteins found in any species of bacterium. (lookformedical.com)
  • HP1383 restriction modification system S subunit HP1388 hypothetical protein HP1390 hypothetical protein HP1396 hypothetical protein HP1397 hypothetical protein HP1400+ iron(III) dicitrate transport protein (fecA) HP1402 type I restriction enzyme R protein (hsdR) HP1410 hypothetical protein HP1411 hypothetical protein HP1412 hypothetical protein HP1415 tRNA delta(2)-isopentenylpyrophosphate transferase (miaA). (lbl.gov)
  • adjacent to host tRNA-Leu gene (red arrow). (elifesciences.org)
  • We confirmed host phylogeny using the sequencing method and analyzed the influence of host phylogeny and bioclimatic zone parameters on the rodent gut microbiome using high-throughput amplicon sequencing of 16S rRNA gene fragments. (microbial-ecology.net)
  • ATG-9 phenotype of MMV291-treated merozoites phenocopying CytD, the MoA of the phage genome were targeted with matching crRNAs and how much epivir cost single-mismatched crRNAs. (clipstonepress.com)
  • The gradual conversion from endosymbiont to organelle during the course of evolution has clearly been accompanied by a dramatic reduction in genome size as the chloroplasts lost most of their genes to the nucleus. (frontiersin.org)
  • Shortly after or even during synthesis, the residues in a protein are often chemically modified by post-translational modification, which alters the physical and chemical properties, folding, stability, activity, and ultimately, the function of the proteins. (transectscience.org)
  • Generally, regulatory genes occur upstream to the structural gene regulated by the regulatory gene. (pediaa.com)
  • Hence, there is a need for developing efficient computational models to predict the interaction between host and pathogen in a genome scale, and find novel candidate effectors and/or their targets. (biomedcentral.com)
  • Methods commonly used to study protein structure and function include immunohistochemistry, site-directed mutagenesis, X-ray crystallography, nuclear magnetic resonance and mass spectrometry. (transectscience.org)
  • This enables us to identify candidate genes underlying glucosinolate diversity, trichome density, and study the genetics of biochemical variation for glucosinolate and saponins. (pacb.com)
  • Various computational and biochemical methods are used to study protein interfaces. (jove.com)
  • HomB protein contributes to the colonization and persistence of H. pylori , and the presence of homB genes affects the number of bacteria adhering to the host cells. (nature.com)
  • Outer membrane proteins (OMPs) are distinctive features of Gram-negative bacteria. (nature.com)
  • Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria. (lookformedical.com)
  • The prokaryotic MORC proteins were widely, but sporadically, distributed in several distantly related bacteria such as proteobacteria, cyanobacteria and actinobacteria, as well as certain crenarchaea and euryarchaea [ 7 ]. (beds.ac.uk)
  • Proteins perform a vast array of functions within organisms, including catalyzing metabolic reactions, DNA replication, responding to stimuli providing structure to cells and organisms, and molecules from one location to another. (transectscience.org)
  • Hyaluronan binding protein 1 (HABP1), also known as C1qBP/C1qR and p32, is a ubiquitous acidic glycoprotein that functions in spermatogenesis and as a receptor for proinflammatory molecules (1, 2). (rndsystems.com)
  • Crowding of asymmetric proteins results in an asymmetric lateral pressure across the membrane which can be used by cells in a number of biological processes involving membrane remodeling. (portlandpress.com)