• Table 1 lists the major structural proteins coded for by the HIV genome. (cdc.gov)
  • gag gene codes for structural proteins which forms the 'body' of the viral particle, among other proteins. (proteopedia.org)
  • Pol gene on the other hand codes for three essential enzymes which are Reverse Transcriptase (RT), Integrase (IN) and Protease (PR), among other proteins. (proteopedia.org)
  • env gene codes for viral envelop proteins. (proteopedia.org)
  • Infection leads to injection of the virus nucleoprotein core (consisting of many gag-derived proteins, full-length genomic RNA, and the reverse transcriptase protein). (ukessays.com)
  • Unspliced full-length mRNA can give rise to gag-pol proteins. (ukessays.com)
  • Full-length genomic unspliced mRNA is bound by gag-derived proteins and incorporated into the budding particle. (ukessays.com)
  • The specificity towards RNA packaging requires higher order interactions of the retroviral gRNA with the structural Gag proteins. (uaeu.ac.ae)
  • This review will compare the determinants of gRNA encapsidation among different retroviruses, followed by an examination of our current understanding of the interaction between diverse viral genomes and heterologous proteins, leading to their cross-/co-packaging. (uaeu.ac.ae)
  • Celecoxib structure A comparative genomic evaluation involving the genome of phage eiAU and that of phage SSL 2009a unveiled that genome regions encoding many putative structural and replica tion proteins are shared by both phages. (hivprotease-signal.com)
  • The predicted gene products with sequence similarity amongst the eiAU and SSL 2009a phage genomes include things like the putative small tail proteins tail tape mea certain, major tail proteins, major capsid proteins, head morphogenesis, phage terminase tiny subunit, and the phage terminase large subunit. (hivprotease-signal.com)
  • Interestingly, other struc tural proteins which includes the host specificity proteins, the tail assembly proteins, and specifically the tail fiber baseplate protein which has become suggested for exclusion in any sequence based mostly phage taxonomy scheme are certainly not shared in between the 2 genomes. (hivprotease-signal.com)
  • The inner nucleocapsid is formed by four proteins (p24, p15, p12, p10) encoded by the gag (group specific antigen) gene. (anipedia.org)
  • Proteins coded by the retroviral gag gene. (uams.edu)
  • A novel cross-phylum family of proteins comprises a KRR1 (YCL059c) gene which is essential for viability of Saccharomyces cerevisiae cells. (nih.gov)
  • Several small genes encode regulatory proteins that enhance virion production or combat host defenses. (mhmedical.com)
  • The full-length mRNA is used for expression of Gag and Gag-Pro-Pol proteins. (peerj.com)
  • Lentiviral gene delivery systems consist of packaging (or helper) plasmids that code for viral structural and regulatory proteins, and a gene transfer vector that contains the transgene expression cassette ( Srinivasakumar, 2001 ). (peerj.com)
  • Antibodies to the HIV-1 major group-specific antigen (GAG) protein p24, and its precursor p55, are the earliest detected after infection by Western blot and tend to decrease or become undetectable with onset or progression of clinical symptoms (4-9). (cdc.gov)
  • gag is short for group-specific antigen. (uams.edu)
  • Initially, piRNAs were described as repeat-associated siRNAs (rasiRNAs) because of their origin from the repetitive elements such as transposable sequences of the genome. (wikipedia.org)
  • The viral gene sequences identified in CFS patients clustered with sequences from PC and both sequences were virtually identical. (phoenixrising.me)
  • ERVs and related sequences are estimated at ~400,000 copies or 4.6% of the human genome, including genomic proviruses like 5' long terminal repeat (LTR)-gag-pol-env-3' LTR ( 1 ). (frontiersin.org)
  • These solo-LTRs contain functional sequences like promoters, enhancers, polyadenylation signals and are frequently located near cellular genes. (frontiersin.org)
  • In order to gain insight into the chromosomal distribution of LTR-retrotransposons in the rice genome, a detailed examination of LTR-retrotransposon sequences on Chromosome 10 was carried out. (biomedcentral.com)
  • Approximately 20% of LTR retrotransposon sequences lie within putative genes. (biomedcentral.com)
  • Based on the results of phylogenetic similarity of 16SrDNA gene sequences, strain DB17 was identified to be Pseudomonas putida. (omicsonline.org)
  • Despite the gene's repetitive and GC-rich sequences, 13% of RPGR gene copies showed mutation correction and conversion to the wild-type allele. (nature.com)
  • Although HIV-1 based gene transfer vectors lack most of the viral coding sequences, it retains a small portion of the gag sequence, and also contains a 5′ splice donor site upstream of gag and frequently a 3′ splice acceptor site further downstream. (peerj.com)
  • All gene transfer vectors also contain cis -sequences for encapsidation, reverse-transcription, and integration. (peerj.com)
  • During an in vitro comparison of HIV-1 and Ty3 nucleoprotein function in RNA dimerization and cDNA synthesis, we discovered a bipartite primer-binding site (PBS) for Ty3 composed of sequences located at opposite ends of the genome. (cnrs.fr)
  • In the current report, a systematic approach is implemented to catalogue regulatory elements within HERVs, as a roadmap to potential functions of HERV sequences in gene networks. (mdpi.com)
  • In the human genome there are six known genes coding for hyaluronidase-like sequences, all having a high degree of homology, but with different tissue distribution, namely hHyal-1 through -4, PH-20/Spam-1 and pseudogene Phyal1, that is transcribed in the human genome but not translated. (biomedcentral.com)
  • Your gene sequences and cells may be patented and sold on the open market without your ever knowing about it. (i-sis.org.uk)
  • Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy. (cdc.gov)
  • Due to their replicative nature, retrotransposons can increase eukaryotic genome size quickly and survive in eukaryotic genomes permanently. (wikipedia.org)
  • It is thought that staying in eukaryotic genomes for such long periods gave rise to special insertion methods that do not affect eukaryotic gene function drastically. (wikipedia.org)
  • When the retroviral DNA is integrated into the host genome they evolve into endogenous retroviruses that influence eukaryotic genomes. (wikipedia.org)
  • So many endogenous retroviruses have inserted themselves into eukaryotic genomes that they allow insight into biology between viral-host interactions and the role of retrotransposons in evolution and disease. (wikipedia.org)
  • LTR Retrotransposons transpose through reverse transcription of an RNA intermediate and are ubiquitous components of all eukaryotic genomes thus far examined. (biomedcentral.com)
  • Both LINEs and SINEs elements, despite the differences in structure and transposition mechanisms ( [44] ), are ubiquitous components of eukaryotic genomes, playing a major role in their evolution. (sisef.it)
  • It is therefore clear that retrotransposable elements build large parts of eukaryotic genomes ( [40] ). (sisef.it)
  • Between the long terminal repeats there are genes that can be transcribed equivalent to retrovirus genes gag and pol. (wikipedia.org)
  • An endogenous retrovirus is a retrovirus without virus pathogenic effects that has been integrated into the host genome by inserting their inheritable genetic information into cells that can be passed onto the next generation like a retrotransposon. (wikipedia.org)
  • XMRV is a simple retrovirus with gag, pol and env genes and unlike HIV or HTLV, has no accessory or regulatory genes. (phoenixrising.me)
  • The identities of these genes provide insights into the mechanism of virus resistance and will help to define new pathways used during retrovirus infection. (biomedcentral.com)
  • It is becoming increasingly apparent that mammalian cells harbor numerous genes that induce intracellular blocks to retrovirus infection [ 1 , 2 ]. (biomedcentral.com)
  • We have been involved in the development of screens and selections for virus resistance genes, and have isolated mutant cell lines after chemical mutagenesis that are profoundly resistant to retrovirus infection. (biomedcentral.com)
  • Retrotransposable elements are important and peculiar genetic components derived from ancient retrovirus insertion inside plants genome. (sisef.it)
  • Further support to this similarity has been provided by the ability of the env-like gene of DmeGypV (the Gypsy endogenous retrovirus of Drosophila melanogaster) to promote infection of Drosophila cells by a pseudotyped vertebrate retrovirus vector. (lookformedical.com)
  • HIV is a typical retrovirus with a small RNA genome of 9300 base pairs. (mhmedical.com)
  • In addition to having a role in the suppression of genomic transposons, various roles of piRNAs have been recently reported like regulation of 3' UTR of protein-coding genes via RNAi, transgenerational epigenetic inheritance to convey a memory of past transposon activity, and RNA-induced epigenetic silencing. (wikipedia.org)
  • DNA transposons encode a transposase which, when translated, catalyses the excision of the transposase gene and its flanking region and its insertion into a different genomic location: a 'jumping' DNA element. (wikipedia.org)
  • Because the retrotransposon contains eukaryotic genome information it can insert copies of itself into other genomic locations within a eukaryotic cell. (wikipedia.org)
  • Taxonomic classification of those E. ictaluri specific phages must rely on a synthesis of morphological and genomic details, taking into consideration that phage evolution continues to be profoundly directed by lateral gene transfer, and that a rational hierarchical technique of phage classification really should be based within the degree of DNA and protein sequence identity for several genetic loci. (hivprotease-signal.com)
  • For example, based on the screening of genomic libraries with a conserved retrotransposon probe, Hirochika and his colleagues [ 24 ] made an estimate of ~1000 retrotransposons totally in the rice genome, which fall into 32 families. (biomedcentral.com)
  • It is best to be aware of these definitions while sticking with the recommendations of the Human Genome Variation Society and to use ' sequence variant ' , ' alteration ' or ' allelic variant ' for any genomic change regardless of their frequency or phenotypic effects. (tripod.com)
  • Genomic DNA from test cells was amplified by PCR using primers for the RPGR region and the PCR products were analyzed by the SURVEYOR® assay (Transgenomic, Omaha, NE) for DNA cleavage activity. (nature.com)
  • Because the phenotype of GRIN1-related neurodevelopmental disorder is often nonspecific and indistinguishable from many other inherited disorders, it is most likely to be diagnosed by either gene-targeted testing (i.e., a multigene panel) (see Option 1) or genomic testing (which does not require the clinician to determine which gene is likely involved) (see Option 2). (rsv-nellingen.de)
  • The array contained 570 unique probes designed against specific regions of more than 40 viral genomes (E. Engel et al. (apsnet.org)
  • At the beginning of the life cycle the retroviral genome is a DNA element integrated into and covalently attached to the DNA of the host cell. (ukessays.com)
  • Pol gene products include enzymes reverse transcriptase, integrase and ribonuclease H domains. (wikipedia.org)
  • Once inside the cell, the nucleoprotein complex accesses intracellular DNA nucleotide triphosphate pools, where the reverse transcriptase protein initiates and creation of a double-stranded DNA copy of the genome of the virus is prepared for integration into the host cell chromosome. (ukessays.com)
  • Reverse transcriptase is the essential enzyme that carries out the reverse transcription process that take the RNA genome to a double-stranded DNA preintegrate form. (ukessays.com)
  • Gag is a polyprotein and is an acronym for Group Antigens (ag). (ukessays.com)
  • Those containing three open reading frames (ORFs), including an env-like gene, may well be considered as endogenous retroviruses. (lookformedical.com)
  • RESULTS: To gain insights into their evolutionary story, a sample of thirteen insect endogenous retroviruses, which represents the largest sample analysed until now, was studied by computer-assisted comparison of the translated products of their gag, pol and env genes, as well as their LTR structural features. (lookformedical.com)
  • Human endogenous retroviruses (HERVs) are a family of endogenous retroviruses that comprise the ~8.93% of the human genome sequence, with a high proportion being human specific. (mdpi.com)
  • Most retrotransposons in the maize genome are LTR, whereas in humans they are mostly non-LTR. (wikipedia.org)
  • On the other hand, LTR-retrotransposons, so called mammalian apparent LTR retrotransposons (MaLRs) represent 3.6% of the genome and lack primer binding sites and gag-pol genes ( 1 ). (frontiersin.org)
  • Plant genomes, in particular, have been found to be comprised of a remarkably high number of LTR retrotransposons. (biomedcentral.com)
  • There is a significant body of direct and indirect evidence that LTR retrotransposons have contributed to gene and genome evolution in plants. (biomedcentral.com)
  • To explore the evolutionary history of long terminal repeat (LTR) retrotransposons and their impact on the genome of Oryza sativa , we have extended an earlier computer-based survey to include all identifiable full-length, fragmented and solo LTR elements in the rice genome database as of April 2002. (biomedcentral.com)
  • LTR-retrotransposons present in the rice genome range in age from those just recently inserted up to nearly 10 million years old. (biomedcentral.com)
  • The cloning and sequencing of amplification products and a Cleaved Amplified Polymorphisms (CAPs) approach on the identified retrotransposons, showed a high level of diversity among the multiple copies of both elements. (sisef.it)
  • Retrotransposons (RNA mediated Class I TEs) are the most widespread class of eukaryotic TE, particularly relevant in shaping plant genomes ( [10] , [44] ). (sisef.it)
  • The observed differences in genome size in plants are accompanied by variations in the content of LTR retrotransposons, demonstrating that such elements might be important players in the evolution of plant genomes, along with polyploidy ( [11] ). (sisef.it)
  • 19 Further analysis of the BLV genome reveals a striking homology to HTLV-I in the gene arrangement, although their nucleotide sequence homology is limited. (anipedia.org)
  • In addition, HIV-1 and HIV-2 genomes exhibit about 60% homology in conserved genes such as gag and pol. (rapidtest.com)
  • These genes have presumably evolved and been maintained in the genome in response to the pathogenic and lethal consequences of infection, and are now thought to constitute an important part of the host defense against these viruses. (biomedcentral.com)
  • We tested whether CRISPR could precisely edit the pathogenic mutation and produce gene-corrected iPSCs for eventual use in autologous transplantation. (nature.com)
  • A multigene panel that includes GRIN1 and other genes of interest (see Differential Diagnosis) is most likely to identify the genetic cause of the condition while limiting identification of variants of uncertain significance and pathogenic variants in genes that do not explain the underlying phenotype. (rsv-nellingen.de)
  • These genes overlap so they encode a protease that processes the resulting transcript into functional gene products. (wikipedia.org)
  • The genome products (red circle) that require protease to process. (proteopedia.org)
  • Crystal Structures of Highly Constrained Substrate and Hydrolysis Products Bound to HIV-1 Protease. (proteopedia.org)
  • Comparative genetic maps within the grass family indicate extensive regions of conserved gene content and orders [ 16 ]. (biomedcentral.com)
  • Transposable elements (TEs) are ancient (retro)-virus insertions inside a host genome and are peculiar mobile genetic elements accounting for a large proportion of repetitive DNA regions ( [29] ). (sisef.it)
  • In this study, we used both genome mining and PCR-based screening to explore the genetic diversity of CylC homologs and their distribution in bacteria. (biomedcentral.com)
  • A combination of genetic and biochemical assays revealed that BtCDH localizes to the cell surface of B. thetaiotaomicron where it enables extracellular GAG degradation. (hal.science)
  • Genetic structure, transforming sequence, and gene product of avian sarcoma virus UR1. (wikidata.org)
  • To prevent companies and governments from stealing genes, invading genetic privacy and undermining human rights and dignity, we urgently need a Genetic Bill of Rights and a Global Ethics Council, Mae-Wan Ho warns of the fall-outs from the human genome project. (i-sis.org.uk)
  • Computer based sequence similarity searches of the nucleic acid databases are considered to be a more accurate method to identify retrotransposon families and estimate TE content and distribution in rice genome [ 28 - 31 ]. (biomedcentral.com)
  • 3566\2946\AAC82569.1\Abelson murine leukemia virus\Abelson murine leukemia virus, complete genome. (or.jp)
  • 3903\2757\CAA24781.1\Abelson murine leukemia virus\Abelson murine leukemia virus genome with v-abl oncogene. (or.jp)
  • The virusis shown as integrated in the murine genome. (or.jp)
  • 4724\492\CAA24782.1\Abelson murine leukemia virus\Abelson murine leukemia virus genome with v-abl oncogene. (or.jp)
  • 3662\492\CAB56205.1\Abelson murine leukemia virus\Abelson (P160) murine leukemia virus (Ab-MLV) abl gene. (or.jp)
  • Mutant line R3-2 exhibited a nearly 1000-fold resistance to infection by genetically marked Moloney murine leukemia virus genomes, and was resistant to pseudotyped viruses utilizing the ecotropic envelope, the amphotropic envelope, or even the VSV G envelope protein. (biomedcentral.com)
  • Many of the final products are associated with the nucleoprotein core of the virion. (uams.edu)
  • gag gene encodes a capsid like protein. (sisef.it)
  • NMR and UV spectroscopic assays revealed that it encodes a novel polysaccharide lyase (PL), hereafter referred to as BtCDH, reflecting its source (B. thetaiotaomicron (Bt)) and its ability to degrade the GAGs CS, dermatan sulfate (DS), and hyaluronic acid (HA). (hal.science)
  • This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. (nih.gov)
  • A comparison of phage eiAU to Enterobacteria phage SSL 2009a was carried out due to the substantial variety of considerable BLAST hits concerning ORFs within the E. ictaluri phage genomes and those respective ORFs within the genome of phage SSL 2009a, which are on normal 34. (hivprotease-signal.com)
  • The retroviral promoter can direct high-level, efficient expression of genes encoded within the viral capsid of its genome using chromatin. (ukessays.com)
  • We have devised a method for the selection of genes from cDNA libraries that suppress the block to virus infection, and so restore virus susceptibility. (biomedcentral.com)
  • The protocol involves the transformation of pools of resistant cells by cDNA expression libraries, followed by the selection for rare virus-sensitive cells, using multiple rounds of selection after infection by marked viral vector genomes. (biomedcentral.com)
  • Gag gene products associate with other retrotransposon transcripts to form virus-like particles. (wikipedia.org)
  • The analysis demonstrated the presence of multiple copies of retrotransposable elements inside the genome of beech, in accordance with the viral quasi-species theory of retrotransposon evolution. (sisef.it)
  • Two copies of the genome are contained in a nucleocapsid core surrounded by a lipid bilayer, or envelope, that is derived from the host cell plasma membrane ( Figure 59-1 ). (mhmedical.com)
  • Luminex has led the field of end-point multiplex amplification and detection technologies with its many FDA-cleared products. (clpmag.com)
  • We conducted a PCR amplification of the Gag-RFP insert using the VF2 and VR primers on the ligation product (pSB1C3 ligated to the Gag + RFP). (igem.org)
  • While we found non-cyanobacterial homologs of these enzymes to be rare, we identified a large number of genes encoding CylC-like enzymes in publicly available cyanobacterial genomes and in our in-house culture collection of cyanobacteria. (biomedcentral.com)
  • The remarkable diversity of natural products (NPs) results from a similarly diverse pool of biosynthetic enzymes [ 2 ]. (biomedcentral.com)
  • Glycosaminoglycans (GAGs) and GAG-degrading enzymes have wide-ranging applications in the medical and biotechnological industries. (hal.science)
  • Nevertheless, it presents a potential opportunity for the discovery of additional GAG-degrading enzymes. (hal.science)
  • Should you wish to have children, your health insurance provider may require prenatal screening of the foetus, or pre-implantation screening of embryos in order to eliminate the 'bad' gene(s). (i-sis.org.uk)
  • DEFINITION Mus musculus 129SVJ mNB-3 gene for neural recognition molecule NB-3, exon 1 and promoter region. (nig.ac.jp)
  • Homologs of CylC are also found in other characterized cyanobacterial secondary metabolite biosynthetic gene clusters. (biomedcentral.com)
  • Genes encoding CylC homologs are widely distributed throughout the cyanobacterial tree of life, within biosynthetic gene clusters of distinct architectures (combination of unique gene groups). (biomedcentral.com)
  • The presumed gene count of 100,000 for human genome drastically went down to around 20,000 after the completion of Human Genome Project. (tripod.com)
  • At the same time, however, an enhanced understanding of the molecular mechanisms involved in these specific interactions makes retroviruses an attractive target for anti-viral drugs, vaccines, and vectors for human gene therapy. (uaeu.ac.ae)
  • How GAGs are metabolized by the HGM is therefore of interest and has been extensively investigated in the model human gut microbe Bacteroides thetaiotaomicron. (hal.science)
  • 100.000 cCREs in total), dispersed within the genome and present in cis-regulatory regions of ~81% of human genes, as calculated following gene enrichment analysis. (mdpi.com)
  • Human Hyal-1 and Hyal-2 are the two major Hyals for the degradation of HA in somatic tissues, hHyal-2 degrades high molecular mass HA to an approximately 20 kDa product, whereas Hyal-1 can degrade high molecular mass HA to small oligomers, primarily to tetrasaccharides [ 12 ]. (biomedcentral.com)
  • These are some of the fall-outs from the Human Genome Project (see Human Genome: The Biggest Sellout in Human History, this issue). (i-sis.org.uk)
  • An intronic mutation may well result in a non-functional gene (like the splicing site mutation in CYP21A2 ). (tripod.com)
  • Deletion of the RRE during reverse-transcription lead to the reconstitution of a functional hygromycin phosphotransferase gene in the target cell. (peerj.com)
  • Comparative genomics of Salmonella enterica serovar Montevideo reveals lineage-specific gene differences that may influence ecological niche association. (cdc.gov)
  • Highly polymorphic regions (such as HLA genes) are not represented either due to difficulty with designing primers because of the lack of constant regions flanking the variants. (tripod.com)
  • Sequence-based analysis enabled by Life Technologies' 3500 Dx system coupled with SeCore kits is the only available technique that identifies more than 5,500 gene variants at the nucleotide level. (clpmag.com)
  • Transcription proceeds through the genome and mRNA is polyadenylated and processed using signals in transcribed regions from the 3′ LTR at the end of the transcribed R (repeat). (ukessays.com)
  • All the spliced forms originate from a single genome-length mRNA transcript. (peerj.com)
  • It includes the tail end of the LacI gene coding region, but no promoter region for that partial gene. (igem.org)
  • Phylogenetic ana lysis of several phage gene merchandise suggests that these phages are similar to these that infect other Enterobacteria hosts. (hivprotease-signal.com)
  • We found that the three phylogenetic trees based respectively on Gag, Pol and Env common motifs are congruent, which suggest a monophyletic origin for these elements. (lookformedical.com)
  • It is becoming clear that vectors based upon adeno-associated virus (AAV) are the vectors of choice for certain gene therapy applications such as muscle delivery. (justia.com)
  • Both should have displayed the end of the RFP, but the VR primer revealed the end of the Gag. (igem.org)
  • Analysis of the VR primer on the Gag-RFP sequence revealed several sites where the VR primer could have annealed with ~9 - 12 bp of complementarity. (igem.org)
  • 295 "Gene escape model: transfer of heavy metal resis -tance genes from E.coli":App. (globalchange.com)
  • This is a direct copy of bases 0365739 through 0365540 of the E. coli K-12 MG1655 genome, Genbank NC_000913 in reverse complement form. (igem.org)
  • The other one is that mutation is any variation in the gene that causes an obvious change in phenotype whereas polymorphisms do not cause any obvious phenotypic variation. (tripod.com)
  • three different genes may cause the same phenotype). (tripod.com)
  • 3) In some laboratories, panel options may include a custom laboratory-designed panel and/or custom phenotype-focused exome analysis that includes genes specified by the clinician. (rsv-nellingen.de)
  • Gag and Pol are made as either Gag protein or a Gag-Pol precursor. (ukessays.com)
  • The bioinformatic examination on the genomes of these 3 E. ictaluri specific bacteriophages corroborate pre viously published data that signifies that these bacterio phages are lytic, and lack any mechanism for lysogenic conversion of their host. (hivprotease-signal.com)
  • Black Seedless) showing a microarray hybridization pattern compatible with a mixed infection of GLRaV-7 and GLRaV-1 was analyzed by ELISA using GLRaV-7 specific antibodies (Agritest, Valenzano, Italy) and reverse transcription (RT)-PCR using virus-specific primers LR7-F: 5′- TAT ATC CCA ACG GAG ATG GC -3′ and LR7-R: 5′- ATG TTC CTC CAC CAA AAT CG -3′ (based on GenBank Accession No. Y15987). (apsnet.org)
  • Antibodies to the polymerase (POL) gene products (p31, p51, and p66) are also commonly detected if these antigens are present on the Western blot strips. (cdc.gov)
  • The RT-PCR product of 393 bp corresponding to a fragment of the HSP70h gene was cloned and sequenced (GenBank Accession No. EU334663), showing 94% nucleotide and 95% amino acid identity when compared with a corresponding region of another GLRaV-9 isolate from the United States (GenBank Accession No. AY297819). (apsnet.org)
  • The 301-bp product was cloned and sequenced (GenBank Accession No. EU588989) showing 93.7% nucleotide and 98% amino acid identity when compared with a corresponding region of another GLRaV-9 isolate (GenBank Accession No. AY297819). (apsnet.org)
  • To identify such genes, we have developed methodologies that allow for the selection of rare virus-sensitive clones arising after transfer of gene libraries into populations of virus-resistant parents. (biomedcentral.com)
  • The presence of as-yet uncharacterized GAG-inducible genes in its genome and of related species, however, is testament to our incomplete understanding of this process. (hal.science)
  • However, unlike other oncogenic retroviruses, deltaretroviruses have an additional region, tax (trans-activating region of the X gene), which has regulatory functions and is oncogenic to host cells. (cdc.gov)
  • Retroviruses are the only animal viruses that integrate into the host cell's genome during the normal growth cycle. (ukessays.com)