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  • liver
  • The Alcohol Research Center unifies investigators from major academic institutions in Southern California to pursue a common mission of being a leader in research, training, and outreach for alcoholic liver and pancreatic diseases (ALPD). (nih.gov)
  • citation needed] Alcohol stimulates the kidneys' excretion of magnesium, which is also increased because of alcoholic and diabetic ketoacidosis, low blood phosphate levels, and hyperaldosteronism resulting from liver disease. (wikipedia.org)
  • The negative effects include increased risk of liver diseases, oropharyngeal cancer, esophageal cancer and pancreatitis. (wikipedia.org)
  • Alcohol abuse by Native Americans has been shown to be associated with development of disease, including sprains and muscle strains, hearing and vision problems, kidney and bladder problems, head injuries, pneumonia, tuberculosis, dental problems, liver problems, and pancreatitis. (wikipedia.org)
  • beverages
  • Beverage-specific effects of additives or by-products such as congeners in alcoholic beverages also play an important role. (wikipedia.org)
  • Some complex organic molecules found in alcoholic beverages known as congeners may play an important role in producing hangover effects because some, such as methanol, are metabolized to the notably toxic substances formaldehyde and formic acid. (wikipedia.org)
  • By causing an imbalance of the NAD+/NADH redox system, alcoholic beverages make normal bodily functions more difficult. (wikipedia.org)
  • Alcoholic beverages are classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen (carcinogenic to humans). (wikipedia.org)
  • Its evaluation states, "There is sufficient evidence for the carcinogenicity of alcoholic beverages in humans. (wikipedia.org)
  • Alcoholic beverages at any quantity are carcinogenic to humans (Group 1). (wikipedia.org)
  • It is well known that ethanol causes cell death at the concentrations present in alcoholic beverages. (wikipedia.org)
  • It was well documented that Mexican Native Americans prepared over forty different alcoholic beverages from a variety of plant substances, such as honey, palm sap, wild plum, and pineapple. (wikipedia.org)
  • The Coahuiltecan in Texas combined mountain laurel with the Agave plant to create an alcoholic drink, and the Pueblos and Zunis were believed to have made fermented beverages from aloe, maguey, corn, prickly pear, pitahaya and even grapes. (wikipedia.org)
  • To the east, the Creek of Georgia and Cherokee of the Carolinas used berries and other fruits to make alcoholic beverages, and in the Northeast, there is some evidence that the Huron made a mild beer made from corn. (wikipedia.org)
  • The majority of aboriginal production and use of alcoholic beverages was in this region. (wikipedia.org)
  • hepatitis
  • The TREAT consortium conducts ground breaking studies in the natural history, pathophysiology, and management of alcoholic hepatitis. (nih.gov)
  • In the United States, NASH affects about 11 million people and alcoholic hepatitis affects about 5 million people. (wikipedia.org)
  • medications
  • There are seven classes of medications associated with acute pancreatitis: statins, ACE inhibitors, oral contraceptives/hormone replacement therapy (HRT), diuretics, antiretroviral therapy, valproic acid, and oral hypoglycemic agents. (wikipedia.org)
  • environmental
  • Our study showing the differential role of p.R122H mutation in various etiologies of CP indicates that this complex disorder is likely influenced by multiple genetic factors as well as environmental factors. (hindawi.com)
  • certain genetic
  • Certain genetic diseases, such as sickle cell anemia, spherocytosis, thalassemia, pyruvate kinase deficiency, and glucose 6-phosphate dehydrogenase deficiency can lead to increased red cell lysis and therefore hemolytic jaundice. (wikipedia.org)
  • In addition, certain genetic factors can amplify the negative effects of acetaldehyde. (wikipedia.org)
  • disease
  • had a more favourable cardiovascular profile and a reduced risk of coronary heart disease than those without the genetic variant. (wikipedia.org)
  • environmental
  • It has been suggested that these associations among CD and other AD may be explained by the sharing of a common pathogenic basis involving genetic susceptibility, similar environmental triggers, and the loss of intestinal barrier secondary to dysfunction of intercellular tight junctions with increased intestinal permeability, and possibly by other undiscovered mechanisms [ 7 , 11 - 16 ]. (hindawi.com)
  • blood
  • High unconjugated bilirubin may be due to excess red blood cell breakdown, large bruises, genetic conditions such as Gilbert's syndrome, not eating for a prolonged period of time, newborn jaundice, or thyroid problems. (wikipedia.org)
  • risk
  • had a more favourable cardiovascular profile and a reduced risk of coronary heart disease than those without the genetic variant. (wikipedia.org)