• Genomic
  • Raza has also used genomic technology to further research the pathology of myelodysplastic syndrome, as well as RNA Sequence and global methylation studies, and was a part of US President Barack Obama's "cancer moonshot" program, reporting to Vice-President Joe Biden. (wikipedia.org)
  • exposure
  • It can be difficult to prove a connection between a suspected exposure and the development of MDS, but the presence of genetic abnormalities may provide some supportive information. (wikipedia.org)
  • cancers
  • Loss of heterozygosity can be identified in cancers by noting the presence of heterozygosity at a genetic locus in an organism's germline DNA, and the absence of heterozygosity at that locus in the cancer cells. (wikipedia.org)
  • complexity
  • The complexity of the biologic, clinical, morphologic, and genetic features of MDSs has led to evolving classification systems, including the French-American-British (FAB) classification, which was introduced in 1982, and the subsequent World Health Organization (WHO) classification (1999), which was most recently updated in 2008. (springer.com)
  • study
  • The study of copper's genetic diseases, which are the focus of intense international research activity, has shed insight into how human bodies use copper, and why it is important as an essential micronutrient. (wikipedia.org)
  • features
  • This region includes more than 20 genes, and researchers believe that the characteristic features of Williams syndrome are probably related to the loss of multiple genes in this region. (wikipedia.org)
  • specific
  • While a few of the specific genes related to Williams syndrome have been identified, the relationship between most of the genes in the deleted region and the signs and symptoms of Williams syndrome is unknown. (wikipedia.org)
  • Therefore
  • They thereby continuously stimulate cell growth and proliferation and lead to the development of leukemias, lymphomas, and myelodysplastic syndromes that are commonly associated with hypereosinophilia and therefore regarded as a sub-type of clonal eosinophilia. (wikipedia.org)