Genetic humans abnormalities drug induced. Medical search. Frequent questions

Novel culture and cryopreservation systems for human pluripotent stem cells and neural stem cells will be presented and their advantages and applicability in the production of high quality advanced therapeutic products or functional screening tools for preclinical research discussed. (selectbiosciences.com)
This presentation will describe the current status of strategies to generate induced pluripotent stem (iPS) cells from mouse and human somatic cells for patient-specific disease modeling and cell therapeutic applications. (selectbiosciences.com)
The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and recapitulation of disease pathologies. (nature.com)
Feric, N. T. & Radisic, M. Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. (nature.com)
To do this, we use a combination of patient-derived and CRISPR-engineered induced pluripotent stem cells (iPSCs). (virginia.edu)
What are Induced Pluripotent Stem Cells? (nationalstemcelltherapy.com)
The creation of induced pluripotent stem cells (iPSCs) is a process that involves taking adult cells and reprogramming them into a state where they can develop into any type of cell in the body. (nationalstemcelltherapy.com)
The potential applications of induced pluripotent stem cells (iPSCs) for neurological disorders are numerous and promising. (nationalstemcelltherapy.com)
Induced pluripotent stem cells (iPSCs) have the potential to revolutionize the treatment of cardiovascular diseases, which are conditions that affect the heart and blood vessels. (nationalstemcelltherapy.com)
Developed in the second decade of the 2000s by researchers including BBRF Scientific Council members Ronald McKay, Ph.D. , Stewart Anderson, M.D. , Fred Gage, Ph.D. and Kristen Brennand, Ph.D. , "human induced pluripotent stem cell" (hiPSC) technology involves harmlessly sampling cells (usually skin cells) from an individual and then genetically reprograming these cells to re-develop as other cell types. (bbrfoundation.org)

MDS was found to be related to genetic mutations or epigenetic modifications, which lead to abnormal autophagy, apoptosis of mature cells, chromosomal abnormalities, and a high level of inflammation in the bone marrow microenvironment ( 4 - 8 ). (frontiersin.org)
Exploring the genetic, molecular and biological features of neural differentiation process from embryonic and patient-specific stem cells may offer an unprecedented chance to understand normal and abnormal human brain development and diseases, with implications for drug development and potential cellular replacement therapy. (yale.edu)
Patterns of hair growth can be abnormal, serving as external markers of underlying structural brain and central nervous system abnormalities. (medscape.com)

A number of scientific papers have been published indicating that LSD might cause structural changes in the chromosomes, genetic mutations, disturbances of embryonic development, and malignant degeneration of cells. (druglibrary.net)
Strande, J. L. Haploinsufficiency MYBPC3 mutations: another stress induced cardiomyopathy? (nature.com)
Genetic diseases that are linked to gene mutations on the X CHROMOSOME in humans (X CHROMOSOME, HUMAN) or the X CHROMOSOME in other species. (bvsalud.org)

The induced mRNAs include both novel and previously described genes, with diverse time courses of expression. (jneurosci.org)
Some of the induced genes, such as CREM, CHOP, and MAP kinase phosphatase-1, may be components of a homeostatic response to excessive stimulation. (jneurosci.org)
A very similar set of genes is induced in unlesioned animals by administration of the psychostimulant cocaine or the antipsychotic eticlopride, although in distinct striatal cell populations. (jneurosci.org)
In contrast to some previously described early genes, most of the novel genes are not induced in cortex by apomorphine, indicating specificity of induction. (jneurosci.org)
They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes. (neurodegenerationresearch.eu)
My research interest focuses on how genes and genetic mechanisms contribute to childhood developmental or late-onset disorders of the human nervous system. (yale.edu)
This is accomplished by introducing specific genes that induce pluripotency into the adult cells. (nationalstemcelltherapy.com)
TP53 protein can induce cell growth arrest, apoptosis, differentiation and DNA repair, and activate or inhibit the expression of downstream genes such as Bax and CDKN1A ( 5 ). (spandidos-publications.com)
Chromosomes are the cellular storage units for genes contained within the nucleus (which is the genetic center) of the cell and are analogous to a spool with the DNA or genetic message being the thread on the spool. (sarcomahelp.org)
Humans have a duplicate set of 23 chromosomes (or a total of 46 chromosomes) in any given cell that carries all of the human genes. (sarcomahelp.org)
The genetic study showed promising results in "silencing" the genes that translate into tau protein, the primary component behind dementia. (medicaldaily.com)
Enfermedades genéticas que estan ligadas a mutaciones en genes del CROMOSOMA X de los seres humanos (CROMOSOMA X HUMANO) o al CROMOSOMA X de otras especies. (bvsalud.org)

Presence of iron is a double-edged sword, it is extremely indispensable to carry various important metabolic processes at the same time its slight excess induces oxidative stress due to production of free radicals, especially the hydroxyl radical which is highly reactive and provoke critical and even irreversible cell injury. (biomedres.us)
A number of genetic, metabolic, and neurologic disorders are associated with recognizable scalp hair abnormalities. (medscape.com)
Clinical inspection of scalp hair characteristics can provide important clues to aid the early identification of genetic, metabolic, and neurologic disorders. (medscape.com)

Aortic stenosis and hypertension result in pressure overload of the left ventricle where the increased wall stress induces hypertrophy and interstitial fibrosis (2-4). (onteenstoday.com)

Phosphorylation of PINK1 is not only required for the PINK1-mediated mitochondrial recruitment of Parkin but also induces its kinase activity toward Parkin. (sdbonline.org)
Resveratrol also down-regulated the increased expressions of vascular endothelial growth factor (VEGF) and kinase insert domain receptor (KDR, or VEGF receptor-2) induced by high glucose. (springer.com)

One example is dynorphin gene expression, which is progressively induced in dorsal striatum by cocaine. (jneurosci.org)
Huntington's is one of the few diseases with a straightforward genetic culprit: One hundred percent of people with a mutated form of the Huntingtin (HTT) gene develop the disease. (neurodegenerationresearch.eu)
To define better cellular events that are specifically vulnerable to WRN deficiency, I used RNA interference (RNAi) to silence the expression of Wrn gene and other RecQ helicases, linked to different clinical phenotypes, in primary human fibroblasts. (yale.edu)
[ 1 3 ] A number of autosomal dominant, autosomal recessive, and X-linked single gene disorders are characterized by hair abnormalities. (medscape.com)

The first group includes papers describing structural changes of the chromosomes produced by LSD in vitro , ** in these experiments various concentrations of LSD are added to cultures of cells from human, animal, or plant tissues in a test-tube. (druglibrary.net)
The possibility of inducing structural changes in the chromosomes by exogenous agents such as radiation, viruses, and a variety of chemicals, has been a subject of great scientific interest for a long time. (druglibrary.net)
The genetic controversy about LSD started in 1967 when Cohen, Marinello and Back (22) published a paper suggesting that LSD should be added to the list of substances capable of causing abnormalities in the chromosomes. (druglibrary.net)

Metronidazole appears in cerebrospinal fluid, saliva, and human milk in concentrations similar to those found in plasma. (nih.gov)

Although operations may improve some abnormalities, many are not surgically treatable due to the lack of nerves and other related structures. (wikipedia.org)

Pazopanib is susceptible to drug-drug interactions with agents that inhibit or induce hepatic CYP 3A4 activity. (nih.gov)
No studies were located in humans or animals regarding the effects on the respiratory, hematological, musculoskeletal, hepatic, renal, and dermal/ocular systems after inhalation exposure to thallium. (cdc.gov)

In mice with surgically induced transmural myocardial infarction, relaxin therapy inhibited scar density. (onteenstoday.com)

Inhibition of VEGF/KDR pathway by using SU5416, a selective inhibitor of KDR, alleviated the hyperpermeability and the cav-1 overexpression induced by high glucose. (springer.com)

The fourth group consists of publications describing the consequences of LSD administration on the growth, development and differentiation of human and animal embryos. (druglibrary.net)

In the present study, we analyzed the proliferation and apoptosis of trophoblasts and human decidual cells in patients with recurrent spontaneous abortion and the related cellular pathway mechanism. (spandidos-publications.com)
The mechanism of recurrent abortion is considered to be related to the proliferation and apoptosis of human decidual cells and cytotrophoblasts ( 4 ). (spandidos-publications.com)

The use of dopamine antagonists as antipsychotics can result in tardive dyskinesia, while drugs such as cocaine that increase striatal dopamine release can cause dependency and addiction (for review, see Hyman, 1996 ). (jneurosci.org)
DESCRIPTION (provided by applicant): The objective of this project is to develop a genetic test, involving the protein, RGS9, to identify patients that are at risk for developing tardive dyskinesia (TD) or L-DOPA induced dyskinesia (LID). (sbir.gov)

In large clinical trials, abnormalities in routine liver tests were common in patients treated with pazopanib, with serum aminotransferase elevations occurring in up to half of patients and total serum bilirubin in approximately one-third. (nih.gov)
Neuropathological studies on post-mortem samples from ASD patients also showed a number of cellular and cytoarchitectural abnormalities at the level of the cerebral cortex, cerebellum, amygdala and forebrain limbic structures. (biomedcentral.com)
We produce iPSCs from easily accessible cells, such as blood or skin, that are acquired from both healthy control individuals and patients with genetic disorders. (virginia.edu)
The ultimate goal of our research is to discover new therapies for patients with currently incurable brain disorders such as autism and drug-resistant pediatric epilepsy. (virginia.edu)
Does Transplantation Induce Aging In Patients? (medicaldaily.com)
Not only does stem-cell technology enable researchers to generate virtually limitless quantities of live human neurons, overcoming the problem of having to rely on postmortem brain tissue to study brain tissue from psychiatric patients. (bbrfoundation.org)
It is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in patients weighing at least 35 kg. (who.int)

DESCRIPTION (provided by applicant): The central goal of this application is to develop a combination product comprising two fully human monoclonal antibodies (mAbs) produced in plants for the prevention of serious disease caused by respiratory syncytial virus (RSV). (sbir.gov)
In a report published in Development , they describe early abnormalities in the way Huntington's neurons look, and how these cells form larger structures that had not previously been associated with the disease. (neurodegenerationresearch.eu)
Suspecting that the disease works differently in humans, the researchers developed a cell-based human system for their research. (neurodegenerationresearch.eu)
Mitochondrial dysfunction has been linked to the pathogenesis of a large number of inherited diseases in humans, including Parkinson's disease, the second most common neurodegenerative disorder. (sdbonline.org)
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
In IBD, the Crohn's and Colitis Canada Genetic, Environmental, Microbial Project research consortium has been studying individuals at increased risk for Crohn's disease because of a first-degree family member with Crohn's disease. (medscape.com)
Huntington's disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. (hdsa.org)
While much study has been devoted to genetic "triggers" of CNS neurodegeneration-notably mutant Htt in Huntington's disease (HD)-such inherited triggers are typically expressed from early fetal development and are fundamentally inaccessible to timely clinical intervention. (hdsa.org)
The realization, that dynamic alteration of genetic programs may also play a fundamental role in pathological processes, led to my focus on how various layers of genomic architecture are influencing a phenotype in health and disease. (yale.edu)
1. Exploitation of rare genetic disorders with Mendelian trait may provide novel insights into mechanisms of common disorders and complex biological processes, such as dementia, diabetes or aging, and recognized disease pathways can offer strategies for prevention, diagnosis, and therapy. (yale.edu)
This project aims to achieve a paradigm shift in antimicrobial drug discovery by finding next generation anti-infectives that prevent disease by blocking pathogen adaptation to host physiology. (nih.gov)
Rather than simply preventing bacteria from growing, these new sophisticated drugs will prevent disease by interfering with a microbe's ability to interact with the human body. (nih.gov)
The Role of Telomeres in Human Disease. (cdc.gov)

Arizona Gov. Doug Ducey, who has signed a law barring abortions based on non-fatal genetic disorders, speaks at an awards luncheon in Scottsdale, Ariz., June 17, 2019. (catholicnewsagency.com)
Among the simple Mendelian disorders of humans, Werner syndrome most closely resembles an acceleration of normal aging. (yale.edu)
There are a number reasons for the medical condition including genetic defects, reproductive system abnormalities, endocrine disorders, immune disorders, infection, thrombosis and environmental factors ( 2 ). (spandidos-publications.com)
Despite claims to the contrary, these psychiatric disorders have no proven genetic, chemical, or biological basis. (bangqu.com)
Of course, genuine diseases or disorders of the brain, such as endocrine disorders or dementia, can change and disrupt human behavior. (bangqu.com)
In this book and in Medication Madness (in press), I describe how psychiatric drugs cause brain disorders that lead to mayhem, murder, and suicide. (bangqu.com)
Mood disorders may also be substance induced, or occur in response to a medical condition . (wikipedia.org)

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. (nih.gov)
Liver test abnormalities are frequent during pazopanib therapy and routine monitoring is recommended at 3 to 4 week intervals. (nih.gov)
Our study demonstrates that pre-treatment of hesperidin for five days reduced the iron induced oxidative stress indicated by the reduction in lipid peroxidation, lactate dehydrogenase, aspartic acid transaminase, and alanine aminotransaminase activities and a rise in the glutathione-s-transferase, catalase, and superoxide dismutase and glutathione contents in the mice liver. (biomedres.us)

Phenotypic features include primary hypogonadism, renal abnormalities, and profound short stature. (sbir.gov)
Clinical trials of pazopanib in malignant diseases in humans have shown activity against renal cell carcinoma and soft tissue sarcoma and promising effects in ovarian and thyroid cancer. (nih.gov)

Structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. (medicaldaily.com)

Thus we have identified novel components of a complex, coordinated genetic program that is induced in striatal cells in response to various dopaminergic manipulations. (jneurosci.org)
Reprogramming of differentiated cells can be efficiently induced in oocytes. (selectbiosciences.com)
Clinical use of human embryonic stem (hES) cells is already being explored in a several phase1 safety trials. (selectbiosciences.com)
The researchers are now using patient-derived motor nerve cells to test potential drugs-with a focus on those that affect lysosomes. (neurodegenerationresearch.eu)
A team has developed a system to model Huntington's in human embryonic stem cells for the first time. (neurodegenerationresearch.eu)
The cells studied were in most cases human white blood cells (lymphocytes). (druglibrary.net)
Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
Various cells and molecules are involved in this process, providing targets for potential drug therapies. (onteenstoday.com)
The approaches that inhibit myofibroblast formation have been demonstrated to prevent cardiac fibrosis, including systemic delivery of antifibrotic drugs, localized delivery of biomaterials, localized delivery of biomaterials and antifibrotic drugs, and localized delivery of cells using biomaterials. (onteenstoday.com)
Free" iron produces hydroxyl radicals from superoxide and hydrogen peroxide via Fenton chemistry inducing oxidative stress in the cells [4]. (biomedres.us)
They can be derived from adult somatic cells, such as skin or blood cells, and reprogrammed using a variety of techniques to change their genetic makeup and revert to an embryonic-like state, supporting them in their growth as they develop into any cell type the body requires and making them one of the top stem cell based therapies to consider. (nationalstemcelltherapy.com)
iPSCs have become a popular area of stem cell research because they offer the potential for regenerative therapies and drug development, as well as provide an alternative to embryonic stem cells. (nationalstemcelltherapy.com)
A deoxyribonucleotide polymer that is the primary genetic material of all cells. (lookformedical.com)
They will take this work one step further and create new model systems to determine the 3-D relationships and functions of different epithelial cell types as the basal cells detect and respond to various drugs, hormones, chemicals and pathogens that appear in the cavity of the organ. (nih.gov)
The team, which included BBRF Scientific Council members Dr. Brennand (who is 2018 BBRF Maltz Prize winner, 2016 Independent Investigator and 2012 Young Investigator) and 2011 BBRF Lieber Prize winner and 2010 and 1998 BBRF Distinguished Investigator Carol A. Tamminga, M.D. , induced skin cells sampled from individuals with schizophrenia to re-develop as neurons of the type found in the forebrain. (bbrfoundation.org)
Many antineoplastic drugs, such as antimetabolites, are most effective when cells are actively dividing. (msdmanuals.com)
Some drugs work only during a specific phase of the cell cycle, requiring prolonged administration to catch dividing cells during the phase of maximal sensitivity. (msdmanuals.com)

Adding to the interest of the finding, there is a known drug that can inhibit the protein in question, suggesting a potential future approach to treat or even prevent schizophrenia in some instances. (bbrfoundation.org)

Others may be part of a genetic program involved in cellular and synaptic plasticity. (jneurosci.org)
The use of mouse models, as well as human diseases resulting from deficiencies in the methylation machinery, have been integral parts of understanding the role of these proteins in development and cellular homeostasis. (caister.com)
In the Shcheglovitov lab, our research is focused on understanding the cellular and molecular mechanisms of human cortical development under both normal and pathological conditions. (virginia.edu)
The cellular kinetics of particular cancers is an important consideration in the design of antineoplastic drug regimens and may influence the dosing schedules and timing intervals of treatment. (msdmanuals.com)

As a clinical psychopharma-cologist, he provides consultations and is active as a medical expert in criminal, malpractice, and product liability lawsuits, often involving the harmful effects of psychiatric drugs. (fdocuments.net)
Increasing epidemiologic, clinical, laboratory, and pathologic evidence supports a link between Zika virus infection during pregnancy and adverse pregnancy and birth outcomes, including pregnancy loss, microcephaly, and brain and eye abnormalities ( 12 - 16 ). (cdc.gov)
Instead, I want to establish from the beginning that I am using these diagnostic terms only for the purpose of consistency with current usage in the various sources on which I am drawing, such as clinical studies, research reports, and Food and Drug Administration (FDA)-approved drug labels. (bangqu.com)
1. History of any illness or any clinical condition that, in the opinion of the investigator, might confound the results of the study or pose an additional risk in administering study drug(s) to the subject. (who.int)

This study established an in vivo PINK1 / Parkin -induced photoreceptor neuron degeneration model in Drosophila with the aim of dissecting the PINK1/Parkin pathway in detail. (sdbonline.org)
The parabrachial to central amygdala pathway is critical to injury-induced pain sensitization in mice. (iasp-pain.org)
The above results demonstrate that RSV ameliorates caveolae-mediated hyperpermeability induced by high glucose via VEGF/KDR pathway. (springer.com)
In line with this, the levels of activated EGFR signaling drop at 48 hours and are comparable in knockout and wild-type mice, suggesting that the EGFR is inactivated through a mig-6-independent mechanism and, that other pathways, like the MET receptor pathway are induced and drive hepatocyte proliferation. (jnksignaling.com)

Transcriptome analysis has been used in autism spectrum disorder (ASD) to unravel common pathogenic pathways based on the assumption that distinct rare genetic variants or epigenetic modifications affect common biological pathways. (biomedcentral.com)
In recent months, two teams of researchers in the UK and the US published complementary findings about the epigenetic origins of schizophrenia that have scientific communities who indulge in 'genetic conspiracy theories' abuzz. (madinamerica.com)

Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved. (lookformedical.com)

We then differentiate iPSCs into cortical neurons or three-dimensional human brain structures called 'organoids' in order to probe genetic abnormalities and the underlying molecular mechanisms. (virginia.edu)
My early studies focused on how conserved genetic programs can change in mature neurons in response to specific, transmitter-receptor mediated signals. (yale.edu)

Endothelial hyperpermeability induced by hyperglycemia is the initial step in the development of atherosclerosis, one of the most serious cardiovascular complications in diabetes. (springer.com)

OBJECTIVE: The mechanisms by which antiepileptic drugs (AEDs) cause birth defects (BDs) are unknown. (ox.ac.uk)
As a second method of analysis, an inner comparability is made between the chance of start defects amongst ladies with first trimester exposures to antiretroviral drugs and the danger of birth defects amongst women with second or third trimester exposures to antiretroviral medicines. (ehd.org)

Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. (lookformedical.com)

these genetic changes alter single protein building blocks (amino acids) in the KCNQ1 protein. (medlineplus.gov)

Here we used two-electrode voltage clamp electrophysiology to compare the actions of CBD with those of the major central endocannabinoid, 2-arachidonoyl glycerol (2-AG) on human recombinant GABAA receptors (synaptic α1-6βg2 and extrasynaptic α4β2δ) expressed on Xenopus oocytes. (researchgate.net)

Peter R. Breggin, MD, has been called "the conscience of psychiatry" for his efforts to reform the mental health fi eld, including his promotion of caring psychotherapeutic approaches and his opposition to the escalat-ing overuse of psychiatric medications, the oppressive diagnosing and drugging of children, electroshock, lobotomy, involuntary treatment, and false biological theories. (fdocuments.net)

Phocomelia is a congenital condition that involves malformations of human arms and legs which results in a flipper-like appendage. (wikipedia.org)

In addition, BCG should not be given to persons who are immunocompromised, including those with human immunodeficiency virus (HIV) infection. (cdc.gov)

Using a combination of molecular biology, biochemistry, imaging, and electrophysiology techniques, we work to better understand the mechanisms underlying human-specific features of cortex development and neurodevelopmental pathologies. (virginia.edu)

The present study was undertaken to understand the modulation of iron induce oxidative stress in mice by hesperidin. (biomedres.us)

As a result, nutrition affects the incidence, natural progression and therapeutic response of malignant diseases, both in humans and in preclinical animal models. (nature.com)

Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. (lookformedical.com)

however, various abnormalities can occur to the limbs and bones. (wikipedia.org)

In the in vitro studies, the blood samples were drawn from normal, healthy persons with no history of prior drug injection, radiation exposure, or recent viral infection. (druglibrary.net)

however, we cannot rule out that other proteins are induced and act together with the EGFR in driving GSK1120212 manufacturer hepatocyte proliferation. (jnksignaling.com)

The gut contains the human body's largest interface between a person and their external environment. (medscape.com)

What Drugs, Substances, or Supplements Interact with Lithostat? (rxlist.com)
Substances that increase the risk of NEOPLASMS in humans or animals. (lookformedical.com)

By the early 1980's, ES and PNET were found to not only have similar features when examined under a microscope, but in greater than 95% of cases they also had an identical genetic abnormality called a translocation (Aurias 1984, Whang-Peng 1984, Burchill 2003). (sarcomahelp.org)

Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load. (ox.ac.uk)
The difference is whether genetic variation is random or directed by the environment and life choices of the parents. (scienceblog.com)

Cardiac fibrosis is a process of pathological extracellular matrix (ECM) remodeling, leading to abnormalities in matrix composition and quality, as well as an impaired heart muscle function [4]. (onteenstoday.com)

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. (nature.com)

The exact embryological and genetic mechanisms underpinning this peculiar anatomical structure are still a matter of debate, but biologists agree that the evolution of the turtle shell lies in the embryonic development of the turtle. (asu.edu)

No human limits were applied for systematic reviews. (cadth.ca)

They are also less susceptible to injury by drugs or irradiation. (msdmanuals.com)

Fig. 6: Calcium transient abnormalities on MYBPC3 -/- cardiac microtissues. (nature.com)
Human iPSC-based cardiac microphysiological system for drug screening applications. (nature.com)

Salistick detects pregnancy by identifying a hormone called human chorionic gonadotropin (hCG), which is present in the body of a pregnant person. (medicaldaily.com)

Data suggest that AED-induced BDs may result from a genome-wide increase of de novo variants in the embryo, a mechanism that we investigated. (ox.ac.uk)
INTERPRETATION: Our study indicates that prenatal AED exposure does not increase the burden of de novo variants, and that this mechanism is not a major contributor to AED-induced BDs. (ox.ac.uk)
Because there is no known single cause, we tested the hypothesis that some cases of myocardial fibrosis in the absence of identifiable causes (primary myocardial fibrosis [PMF]) are associated with genetic variants. (onteenstoday.com)

R torques are mucin degraders that induce an increase in other mucin-using bacteria, which can contribute to gut-barrier compromise. (medscape.com)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Metronidazole Injection USP and other antibacterial drugs, Metronidazole Injection USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)

There are few data in humans on the cardiovascular effects of thallium following inhalation. (cdc.gov)

SB 1457, signed into law April 27 by Gov. Doug Ducey, most notably prohibits abortions done solely because of a nonlethal genetic abnormality, such as Down syndrome. (catholicnewsagency.com)

Anatomy45

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