• Stroke
  • The main objective of this study is to examine empathy in patients suffering from stroke (various locations with an emphasis on frontal stroke), Fronto-temporal dementia, Alzheimer and Parkinson diseases. (clinicaltrials.gov)
  • Side effects of moyamoya disease are most likely to first appear with an ischemic stroke, hemorrhagic stroke, or a mini-stroke, also known as a transient ischemic attack (TIA). (naturalpedia.com)
  • Moyamoya disease causes an ischemic stroke, hemorrhagic stroke, or a mini-stroke, which in turn causes weakness or numbness in an arm or leg, difficulty speaking, or paralysis affecting one side of the body. (naturalpedia.com)
  • In children, the first symptom of Moyamoya disease is often stroke, or recurrent transient ischemic attacks (TIA, commonly referred to as "mini-strokes"), frequently accompanied by muscular weakness or paralysis affecting one side of the body, or seizures. (uic.edu)
  • 9-11 The prevalence of Fabry disease in young patients with cryptogenic stroke was reported to be as high as 4.9% in men and 2.4% in women. (ahajournals.org)
  • The aim of the Belgian Fabry Study (BeFaS) was to prospectively assess the frequency of Fabry disease in young Belgian patients with neurologic hallmarks of this disease, namely, stroke, unexplained white matter lesions, and vertebrobasilar dolichoectasia. (ahajournals.org)
  • Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL), is an inherited disease with symptoms of stroke, hair loss, and low back pain. (wikipedia.org)
  • Brain injuries can also be the result of a stroke as the resulting lack of oxygen can cause damage to the location of the cerebrovascular accident (CVA). (wikipedia.org)
  • encephalitis
  • Diffuse Lewy body disease Drug-induced parkinsonism ("pseudoparkinsonism") due to drugs such as antipsychotics, metoclopramide, sertraline, fluoxetine or the toxin MPTP Encephalitis lethargica Essential tremor, an illness which has some diagnostic overlap with Parkinson's disease Orthostatic tremor MDMA addiction and frequent use has been linked to Parkonsonism. (wikipedia.org)
  • arteries
  • Currently, there are no available medications that can reverse the narrowing of the arteries in moyamoya disease. (naturalpedia.com)
  • Without surgery, the majority of individuals with Moyamoya disease will experience mental decline and multiple strokes because of the progressive narrowing of arteries. (neurologycolorado.com)
  • Like the blood vessels around which they form, perivascular spaces are found in both the subarachnoid space and the subpial space.Perivascular spaces surrounding arteries in the cerebral cortex and the basal ganglia are separated from the subpial space by one or two layers of leptomeninges, respectively, as well as the pia mater. (wikipedia.org)
  • abnormalities
  • The specific causes of neurological problems vary, but can include genetic disorders, congenital abnormalities or disorders, infections, lifestyle or environmental health problems including malnutrition, and brain injury, spinal cord injury or nerve injury. (wikipedia.org)
  • These conditions are listed below: Perinatal (during birth) cerebral injury Kernicterus Cerebrovascular diseases Drug induced Central nervous system tumor Peripheral or central trauma Infectious or post infectious encephalopathies Toxins Metabolic Paraneoplastic syndromes Central pontine myelinolysis Secondary spasmodic torticollis is diagnosed when any of the following are present: history of exogenous insult or exposure, neurological abnormalities other than dystonia, abnormalities on brain imaging, particularly in the basal ganglia. (wikipedia.org)
  • autosomal
  • This includes: autosomal dominant polycystic kidney disease, neurofibromatosis type I, Marfan syndrome, multiple endocrine neoplasia type I, pseudoxanthoma elasticum, hereditary hemorrhagic telangiectasia and Ehlers-Danlos syndrome types II and IV. (wikipedia.org)
  • stenosis
  • The service manages the full range of neurovascular diseases including aneurysms, arterio-venous malformations, cavernous malformations, carotid stenosis, and intracranial occlusive disease requiring endovascular stenting or extracranial-intracranial bypass. (uic.edu)
  • nervous system
  • Fundamental pathologic, translational, and clinical processes and genetic predispositions that afflict the nervous system. (rochester.edu)
  • The body systems harmed by moyamoya disease include the nervous system and the cardiovascular system. (naturalpedia.com)
  • acute pandysautonomia is one form of an autonomic neuropathy, which is a collection of various syndromes and diseases which affect the autonomic neurons of the autonomic nervous system (ANS). (wikipedia.org)
  • movement
  • Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. (stanford.edu)
  • Excessive levels of their intermediate breakdown products (glutaric acid, glutaryl-CoA, 3-hydroxyglutaric acid, glutaconic acid) can accumulate and cause damage to the brain (and also other organs), but particularly the basal ganglia, which are regions that help regulate movement. (wikipedia.org)
  • gene
  • Three years previously, he had been diagnosed with CADASIL by genetic testing for mutation in the Notch 3 gene. (springeropen.com)
  • PETDEImaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET. (clinicaltrials.gov)
  • The aim of this study is to measure the availability of the PDE10A enzyme in Huntington disease gene expansion carriers (HDGECs) using the recently developed radioligand [18F]MNI-659. (clinicaltrials.gov)
  • Signs
  • The most common clinical manifestations are migraine headaches and transient ischemic attacks or strokes, which usually occur between 40 and 50 years of age, although MRI is able to detect signs of the disease years prior to clinical manifestation of disease. (wikipedia.org)
  • progression
  • Male hemizygotes are generally more severely affected than are heterozygous females, but disabling clinical features and disease progression often also occur in female patients. (ahajournals.org)
  • If so, does the severity of loss of heart nerves affect disease progression and survival? (clinicaltrials.gov)
  • Patients
  • Conclusion- α-GAL A deficiency may play a role in up to 1% of young patients presenting with cerebrovascular disease. (ahajournals.org)
  • 15 Epidemiologic studies have reported the condition in 0.2% to 1.2% of patients with end-stage renal disease 4-8 and in 1% to 6.3% of patients with unexplained hypertrophic cardiomyopathy. (ahajournals.org)
  • The disease is rare and has only been diagnosed in about 50 patients, mostly of Japanese descent but few of Chinese and Spanish descent. (wikipedia.org)
  • particularly
  • Bilateral striopallidodentate calcinosis (BSPDC, also erroneously called Fahr disease) is characterized by the accumulation of calcium deposits in different brain regions, particularly the basal ganglia and dentate nucleus, and is often associated with neurodegeneration. (orpha.net)
  • methods
  • The Illinois Brain Aneurysm Center offers the most comprehensive care from a highly experienced team dedicated to developing and implementing the best methods for treating this disease. (uic.edu)
  • white
  • Initial hypodensity or loss of grey-white differentiation after 3-6hrs (grey becomes isodense to white esp cortical ribbon sign, loss of basal ganglia) due to reduced CBV, hence the earlier this occurs the worse the prognosis (profound perfusion defect). (radnotes.co.nz)
  • Studies
  • These studies, which range from clinical trials to investigations of basic biological mechanisms, are aimed at discovering how and why diseases develop in the brain, and focus on finding ways to prevent, treat, or cure them. (neurologycolorado.com)
  • While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. (wikipedia.org)
  • centers
  • The Centers for Disease Control (CDC) issued a cautionary statement (MMWR 54;125) regarding the use of several commercial tests. (wikipedia.org)
  • factors
  • It is unknown what causes a brain aneurysm, however, research in the field suggests there are both genetic and environmental factors that contribute to their appearance and possible growth and possible rupture. (uic.edu)
  • With the exception of increasing age, none of the evidence for non-genetic risk factors is universally accepted. (rcpsych.org)
  • DNA Banking (this is optional): Subjects will have whole blood drawn sample for DNA banking to support genetic research of human disease and human genetic factors. (clinicaltrials.gov)