• Symptoms
  • The National Institutes of Health recommend considering the evaluation of an underlying celiac disease in people with unexplained neurological symptoms, particularly peripheral neuropathy or ataxia. (wikipedia.org)
  • Although changes in motor symptoms were not hypothesized, the Unified Huntington Disease Rating Scale motor examination was administered at every visit. (clinicaltrials.gov)
  • Parkinson's disease has been reported to affect approximately 1 percent of Americans over 50 years of age, 1 but unrecognized early symptoms of the disease may be present in as many as 10 percent of those over 60 years of age. (aafp.org)
  • 2 Patients with the classic phenotype of Fabry disease usually present in childhood with pain crises, acroparesthesia, hypohidrosis, gastrointestinal symptoms, angiokeratoma, and corneal abnormalities. (ahajournals.org)
  • 14 Given the nonspecific presenting symptoms and delayed presentation, atypical variants of Fabry disease might be underdiagnosed. (ahajournals.org)
  • It is thought that the calcifications observed are a marker of the disease rather than a cause of the clinical symptoms. (orpha.net)
  • This research aims to help us better understand the patterns and timing of nerve degeneration relatively early in the disease, and how this affects symptoms and progression. (clinicaltrials.gov)
  • Parkinsonism is found in Parkinson's disease (after which it is named), however a wide range of other causes may lead to this set of symptoms, including some toxins, a few metabolic diseases, and a handful of neurological conditions other than Parkinson's disease. (wikipedia.org)
  • Differentiating some kinds of atypical Parkinson: Northwest Parkinson Foundation Before Parkinson's disease is diagnosed, the differential diagnoses include: AIDS can sometimes lead to the symptoms of secondary parkinsonism, due to commonly causing dopaminergic dysfunction. (wikipedia.org)
  • Paraneoplastic syndrome: neurological symptoms caused by antibodies associated with cancers Genetic Rapid onset dystonia parkinsonism Parkin mutation X-linked dystonia parkinsonism Autosomal recessive juvenile parkinsonism Aminoff MJ, Greenberg DA, Simon RP (2005). (wikipedia.org)
  • These intermediate breakdown products are particularly prone to affect the basal ganglia, causing many of the signs and symptoms of glutaric acidemia type 1. (wikipedia.org)
  • Addison's disease, even in subclinical form, may mimic many of the symptoms of anorexia nervosa. (wikipedia.org)
  • neurodegenerative
  • While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. (wikipedia.org)
  • While many normal brains will show a few dilated spaces, an increase in these has been shown to correlate with the incidence of several neurodegenerative diseases, making the spaces a popular topic of research. (wikipedia.org)
  • arteries
  • Without surgery, the majority of individuals with Moyamoya disease will experience mental decline and multiple strokes because of the progressive narrowing of arteries. (neurologycolorado.com)
  • Like the blood vessels around which they form, perivascular spaces are found in both the subarachnoid space and the subpial space.Perivascular spaces surrounding arteries in the cerebral cortex and the basal ganglia are separated from the subpial space by one or two layers of leptomeninges, respectively, as well as the pia mater. (wikipedia.org)
  • Signs
  • The most common clinical manifestations are migraine headaches and transient ischemic attacks or strokes, which usually occur between 40 and 50 years of age, although MRI is able to detect signs of the disease years prior to clinical manifestation of disease. (wikipedia.org)
  • abnormalities
  • Because it tends to run in families, researchers think that Moyamoya disease is the result of inherited genetic abnormalities. (neurologycolorado.com)
  • These conditions are listed below: Perinatal (during birth) cerebral injury Kernicterus Cerebrovascular diseases Drug induced Central nervous system tumor Peripheral or central trauma Infectious or post infectious encephalopathies Toxins Metabolic Paraneoplastic syndromes Central pontine myelinolysis Secondary spasmodic torticollis is diagnosed when any of the following are present: history of exogenous insult or exposure, neurological abnormalities other than dystonia, abnormalities on brain imaging, particularly in the basal ganglia. (wikipedia.org)
  • brain
  • These studies, which range from clinical trials to investigations of basic biological mechanisms, are aimed at discovering how and why diseases develop in the brain, and focus on finding ways to prevent, treat, or cure them. (neurologycolorado.com)
  • A neurological examination can to some extent assess the impact of neurological damage and disease on brain function in terms of behavior, memory or cognition. (wikipedia.org)
  • Dr Appelboom is focused on advancing minimally invasive surgical techniques for diseases of the brain and spine. (stanford.edu)
  • Bilateral striopallidodentate calcinosis (BSPDC, also erroneously called Fahr disease) is characterized by the accumulation of calcium deposits in different brain regions, particularly the basal ganglia and dentate nucleus, and is often associated with neurodegeneration. (orpha.net)
  • A variety of conditions can cause brain injury, from external factors to diseases. (wikipedia.org)
  • Lifestyle diseases including hypertension, smoking, excessive alcoholism, and obesity are associated with the development of brain aneurysms. (wikipedia.org)
  • Excessive levels of their intermediate breakdown products (glutaric acid, glutaryl-CoA, 3-hydroxyglutaric acid, glutaconic acid) can accumulate and cause damage to the brain (and also other organs), but particularly the basal ganglia, which are regions that help regulate movement. (wikipedia.org)
  • nervous system
  • acute pandysautonomia is one form of an autonomic neuropathy, which is a collection of various syndromes and diseases which affect the autonomic neurons of the autonomic nervous system (ANS). (wikipedia.org)
  • Patients
  • Additional adjunctive therapies include physical therapy, nutritional counseling and techniques to help patients manage emotional and cognitive changes related to the disease. (aafp.org)
  • Conclusion- α-GAL A deficiency may play a role in up to 1% of young patients presenting with cerebrovascular disease. (ahajournals.org)
  • Male hemizygotes are generally more severely affected than are heterozygous females, but disabling clinical features and disease progression often also occur in female patients. (ahajournals.org)
  • 15 Epidemiologic studies have reported the condition in 0.2% to 1.2% of patients with end-stage renal disease 4-8 and in 1% to 6.3% of patients with unexplained hypertrophic cardiomyopathy. (ahajournals.org)
  • The disease is rare and has only been diagnosed in about 50 patients, mostly of Japanese descent but few of Chinese and Spanish descent. (wikipedia.org)
  • commonly
  • However, it is more commonly prescribed for nausea and vomiting due to motion sickness or other sources such as chemotherapy, vertigo, or Ménière's disease. (wikipedia.org)
  • chronic
  • In fact, it is one of only a select few drugs that has shown a beneficial effect in the chronic treatment of the vertigo and tinnitus, associated with Meniere's disease. (wikipedia.org)
  • result
  • Without treatment, Moyamoya disease can be fatal as the result of intracerebral hemorrhage. (neurologycolorado.com)
  • Intracranial aneurysms may result from diseases acquired during life, or from genetic conditions. (wikipedia.org)
  • Autonomic neuropathies may be the result of an inherited condition or they may be acquired due to various premorbid conditions such as diabetes and alcoholism, bacterial infection such as Lyme disease or a viral illness. (wikipedia.org)
  • white
  • Initial hypodensity or loss of grey-white differentiation after 3-6hrs (grey becomes isodense to white esp cortical ribbon sign, loss of basal ganglia) due to reduced CBV, hence the earlier this occurs the worse the prognosis (profound perfusion defect). (radnotes.co.nz)
  • centers
  • The Centers for Disease Control (CDC) issued a cautionary statement (MMWR 54;125) regarding the use of several commercial tests. (wikipedia.org)
  • Infectious
  • Cardiology -- Dermatology -- Endocrinology -- Epidemiology and Preventive Medicine -- Ethics and Legal Issues -- Gastrointestinal -- Hematology/Oncology -- Infectious Disease -- Musculoskeletal and Connective Tissue -- Neurology -- Obstetrics -- Gynecology -- Pediatrics -- Psychiatry -- Pulmonary -- Renal/Genitourinary -- Selected Topics in Emergency Medicine. (stanford.edu)
  • conditions
  • Genetic conditions associated with connective tissue disease may also be associated with the development of aneurysms. (wikipedia.org)
  • Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). (wikipedia.org)
  • While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. (wikipedia.org)