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  • encodes
  • This gene encodes a component of 25-hydroxyvitamin D3-1-alpha-hydroxylase, the enzyme responsible for the hydroxylation of 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3, the most active form of vitamin D. Children with vitamin D-dependent rickets have typical findings associated with the malabsorption of calcium. (ctgt.net)
  • This gene encodes two proteins, p16 and p14ARF, which are transcribed from the same second and third exons but alternative first exons: p16 from exon 1α and ARF from exon 1β. (wikipedia.org)
  • bacteria
  • Pathogenic bacteria carry virulence genes, but sometimes pathogens and non-pathogens are closely related, behave the same way and live in the same environments. (reference.com)
  • For example, the bacteria that cause cholera only differ from harmless strains by carrying a few genes that allow the bacteria to produce a dangerous toxin. (reference.com)
  • variation
  • For example, one person may be carrying several variations of the gene for eye color (i.e., brown, green, blue) , but someone else may be carrying only one variation of the gene for eye color (i.e., brown). (66.228.45)
  • Humans
  • Dogs with dominant genes for hairlessness can pass their attributes to their offspring in natural conditions, that is, not under the control of humans. (wikipedia.org)
  • coat
  • Expression of the panda gene is exhibited openly on any coat that is not already white. (wikipedia.org)
  • A dilute black (BB or Bb) dog is generally known as blue, but a dog with a merle coat does not test BB or Bb but still is a blue dilute from the "merle" gene The merle gene creates mottled patches of color in a solid or piebald coat, blue or odd-colored eyes, and can affect skin pigment as well. (wikipedia.org)
  • carries
  • The coloration is present from birth and does not change throughout the horse's lifetime, unless the horse also carries the gray gene. (wikipedia.org)
  • disorder
  • Aims Autosomal-dominant hypercholesterolaemia (ADH) is a heterogeneous common disorder, and uncovering the molecular determinants that underlie ADH is a major focus of cardiovascular research. (bmj.com)
  • This disorder has been linked to the PHEX gene. (ctgt.net)
  • In many cases people are not aware that they carry a relevant gene until they have children who begin to show signs of having the disorder. (wikipedia.org)
  • expression
  • The present study was carried out to investigate the possible etiology and pathology of cystic ovarian follicles by determining the expression levels of mRNA for LH-r gene in follicular cells of dominant follicles in comparison with cystic ovarian follicles in Iraqi cows. (medcraveonline.com)
  • The up-regulation of expression of genes for LH-r in granulose cells and down-regulation of expression of genes for FSH-r were associated with Growth of follicles until become of graafian follicles . (medcraveonline.com)
  • There are many studies like Ginzinger DG and Barber RD used this technique to explained the gene expression levels and measured the mRNA transcript levels in a quantitative fashion by combining the two technologies real-time PCR with reveres transcription (real time -PCR). (medcraveonline.com)
  • One theory holds that such horses carry the frame gene, but so minimal in expression that they appear solid. (wikipedia.org)
  • Vitamin
  • John's Wort with Ginkgo Biloba is an effective natural treatment for mild depression LifeTek St John's St. Color Blindness Dominant Gene Liver Damage Vitamin you may have pain and increased sensitivity to light. (kojoti.eu)
  • creates
  • The sabino pattern is one of the most complex, as there has been one gene identified, SB-1, that creates one type of sabino patterning, but not all sabino-patterned horses carry it. (wikipedia.org)
  • carry
  • Just as some individuals today carry genes to produce descendants with different color hair and eyes, our first parents, Black Africans, possessed genes to produce all the varieties and races of men. (66.228.45)
  • different
  • Certain "modifying genes" work in tandem (co-dominate expressive) with the merle gene to create a completely different look to the pattern. (wikipedia.org)
  • protein
  • The RPS6KA3 gene makes a protein that is involved with signaling within cells. (wikipedia.org)
  • Researchers believe that this protein helps control the activity of other genes and plays an important role in the brain. (wikipedia.org)
  • The protein RSK2 which is encoded by the RPS6KA3 gene is a kinase which phosphorylates some substrates like CREB and histone H3. (wikipedia.org)
  • clinical
  • Thanks to success in preclinical studies funded in part by the Foundation Fighting Blindness, the Irish biopharmaceutical company Genable Technologies has received a €5 million (equivalent to about $6.8 million) venture capital investment to advance its gene therapy for autosomal dominant retinitis pigmentosa (adRP) into a clinical trial. (blindness.org)
  • target
  • The rhodopsin gene is an important target for treatment, because it can affect so many members of so many families," says Dr. Rose. (blindness.org)
  • growth
  • These two are the "dominant genes": Decision rights and information correlate most strongly with execution ability and agility, which, in turn, correlate strongly with superior profitability and growth. (pwc.com)
  • body
  • These 31 data sets - collectively representing 26,743 observations - form the basis of the "dominant gene" analysis (although the full body of research has informed and confirmed our point of view). (pwc.com)